Official EU label nameGlossary entry 7866

CYCLOHYDROXYPROLYL SERINE

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

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Resolved identifiers

Resolved substance identity

CAS:211868-63-2

Ingredient index records:

CYCLOHYDROXYPROLYL SERINE

Cosmetic functions: HUMECTANT, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-7-hydroxy-3-(hydroxymethyl)-, (3S,7R,8aS)-,(3S,7R,8aS)-Hexahydro-7-hydroxy-3-(hydroxymethyl)pyrrolo[1,2-a]pyrazine-1,4-dione

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1 matched or reported name

CYCLOHYDROXYPROLYL SERINE

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name CYCLOHYDROXYPROLYL SERINE.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 211868-63-2

CAS 211868-63-2PubChem CID 9815587

Cyclo-trans-4-L-Hydroxyprolyl-L-serine

IUPAC name: (3S,7R,8aS)-7-hydroxy-3-(hydroxymethyl)-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione

Molecular formula: C8H12N2O4
Molecular weight: 200.19 g/mol
Exact mass: 200.07970687 Da
XLogP3: -1.7
Topological polar surface area: 89.9 Å²
Hydrogen-bond donors: 3
Hydrogen-bond acceptors: 4
Covalent units: 1
Defined stereocentres: 3

Also known as

JBP485JBP 485(3S,7R,8aS)-Hexahydro-7-hydroxy-3-(hydroxymethyl)-pyrrolo[1,2-a]pyrazine-1,4-dione(3S,7R,8aS)-7-hydroxy-3-(hydroxymethyl)-octahydropyrrolo[1,2-a]piperazine-1,4-dioneGLXC-15336HY-135627CS-0113644

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External database identifiers

ChEMBL:CHEMBL2229108
EPA DTXSID:DTXSID701043599
PubMed:29964132
PubMed:23707770
PubMed:22992436
PubMed:21712612

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal US EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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