Official EU label nameGlossary entry 28157

SYNEPHRINE HCl

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

0 markets with evidence

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Evidence gaps

Resolved identifiers

Resolved substance identity

CAS:5985-28-4

EC:227-804-6

Ingredient index records:

SYNEPHRINE HCL

Cosmetic functions: ANTIOXIDANT, HAIR CONDITIONING, SKIN CONDITIONING

Benzenemethanol, 4-hydroxy-\a-[(methylamino)methyl]-, hydrochloride (1:1)

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1 matched or reported name

SYNEPHRINE HCL

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name SYNEPHRINE HCl.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 5985-28-4

CAS 5985-28-4PubChem CID 42609626

Synephrine hydrochloride

IUPAC name: 4-[1-hydroxy-2-(methylamino)ethyl]phenol;hydrochloride

Molecular formula: C9H14ClNO2
Molecular weight: 203.66 g/mol
Exact mass: 203.0713064 Da
Topological polar surface area: 52.5 Å²
Hydrogen-bond donors: 4
Hydrogen-bond acceptors: 3
Covalent units: 2
Defined stereocentres: 0

Also known as

Synephrine HClOxedrine hydrochlorideoxedrine HClOcuton (TN)EN5D1IH09SUNII-EN5D1IH09SSYNEPHRINE HYDROCHLORIDE [MI]OXEDRINE HYDROCHLORIDE [MART.]

16 more reported names

OXEDRINE HYDROCHLORIDE [WHO-DD]EINECS 227-804-6p-Methylaminoaethanolphenol hydrochloridp-Methylaminoethanol phenol hydrochloridep-Methylaminoaethanolphenol hydrochlorid [German](RS)-1-(4-HYDROXYPHENYL)-2-(METHYLAMINO)ETHANOL HYDROCHLORIDEOXEDRINE HYDROCHLORIDE (MART.)l-1-p-Hydroxyphenyl-2-methylamino-1-ethanol hydrochloridep-Hydroxy-alpha-(methylaminomethyl)benzyl alcohol hydrochlorideBenzenemethanol, 4-hydroxy-alpha-((methylamino)methyl)-, hydrochlorideOcutonBENZYL ALCOHOL, p-HYDROXY-alpha-((METHYLAMINO)METHYL)-, HYDROCHLORIDERefChem:186992227-804-64-[1-hydroxy-2-(methylamino)ethyl]phenol hydrochloride4-(1-Hydroxy-2-(methylamino)ethyl)phenol hydrochloride

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External database identifiers

EPA DTXSID:DTXSID70975251
PubMed:1392

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal US EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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