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Official EU label nameGlossary entry 28156

SYNEPHRINE

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

0 markets with evidence
Markets checked
13
Markets with evidence
0
Evidence gaps
13
Resolved identifiers
1

Resolved substance identity

CAS:94-07-5
Ingredient index records:
SYNEPHRINE
Cosmetic functions: SKIN PROTECTING

4-[1-hydroxy-2-(methylamino)ethyl]phenol

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1 matched or reported name
SYNEPHRINE

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name SYNEPHRINE.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 94-07-5
CAS 94-07-5PubChem CID 7172

Synephrine

Synephrine is a phenethylamine alkaloid that is 4-(2-aminoethyl)phenol substituted by a hydroxy group at position 1 and a methyl group at the amino nitrogen. It has a role as an alpha-adrenergic agonist and a plant metabolite. It is a member of ethanolamines, a member of phenols and a phenethylamine alkaloid. It is a conjugate base of a synephrinium. — ChEBI

IUPAC name
4-[1-hydroxy-2-(methylamino)ethyl]phenol
Molecular formula
C9H13NO2
Molecular weight
167.20 g/mol
Exact mass
167.094628657 Da
XLogP3
-0.6
Topological polar surface area
52.5 Ų
Hydrogen-bond donors
3
Hydrogen-bond acceptors
3
Covalent units
1
Defined stereocentres
0

Also known as

Oxedrinep-SynephrineParasympatolAnaleptinSimpalonSympatolSynthenateSympathol
16 more reported names
EthapheneDL-SYNEPHRINE4-(1-Hydroxy-2-(methylamino)ethyl)phenolAdvantra z1-(4-Hydroxyphenyl)-2-methylaminoethanolNSC-166285NSC-170956PEG5DP7434CHEBI:29081beta-Methylamino-alpha-(4-hydroxyphenyl)ethyl alcohol1-(4-Hydroxyphenyl)-2-(methylamino)ethanolBenzenemethanol, 4-hydroxy-alpha-((methylamino)methyl)-4-Hydroxy-alpha-((methylamino)methyl)benzenemethanolp-Hydroxy-alpha-((methylamino)methyl)benzyl alcoholS-38537-9p-Hydroxy-alpha-[(methylamino)methyl]benzyl alcohol
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External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

Each link searches that source for this identity. A link is a research route, not a claim that the source holds an exact record. What each source is, and its legal weight

Cosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortalUS EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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