Official EU label nameGlossary entry 10959

GINSENOSIDE RE

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

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Resolved identifiers

Resolved substance identity

CAS:52286-59-6

Ingredient index records:

GINSENOSIDE RE

Cosmetic functions: ANTIOXIDANT, HUMECTANT, SKIN CONDITIONING

Ginsenoside B2,\b-D-Glucopyranoside, (3.\b.,6.\a.,12.\b.)-20-(.\b.-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-(6-deoxy-.\a.-L-mannopyranosyl)-

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1 matched or reported name

GINSENOSIDE RE

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name GINSENOSIDE RE.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 52286-59-6

CAS 52286-59-6PubChem CID 441921

Ginsenoside Re

Ginsenoside Re is a ginsenoside found in Panax ginseng that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 6 and 20 have been converted to the corresponding alpha-L-rhamnopyranosyl-(12)-beta-D-glucopyranoside and beta-D-glucopyranoside respectively, and in which a double bond has been introduced at the 24-25 position. It has a role as an antioxidant, an antineoplastic agent, a neuroprotective agent, an anti-inflammatory agent, a nephroprotective agent and a plant metabolite. It is a 3beta-hydroxy-4,4-dimethylsteroid, a beta-D-glucoside, a tetracyclic triterpenoid, a 3beta-hydroxy steroid, a 12beta-hydroxy steroid, a disaccharide derivative and a ginsenoside. It derives from a hydride of a dammarane. — ChEBI

IUPAC name: (2S,3R,4R,5R,6S)-2-[(2R,3R,4S,5S,6R)-2-[[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-dihydroxy-4,4,8,10,14-pentamethyl-17-[(2S)-6-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhept-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6-yl]oxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-6-methyloxane-3,4,5-triol

Molecular formula: C48H82O18
Molecular weight: 947.2 g/mol
Exact mass: 946.55011576 Da
XLogP3: 1.6
Topological polar surface area: 298.0 Å²
Hydrogen-bond donors: 12
Hydrogen-bond acceptors: 18
Covalent units: 1
Defined stereocentres: 26

Also known as

Ginsenoside B2Panaxoside REginsenoside-ReSanchinoside ReNSC 308877NSC-30887746F3R0BL3ICHEBI:77148

16 more reported names

RefChem:37695Chikusetsusaponin IVcGinsenoside Re (Standard)b-D-Glucopyranoside,(3b,6a,12b)-20-(b-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-(6-deoxy-a-L-mannopyranosyl)-beta-D-Glucopyranoside, (3beta,6alpha,12beta)-20-(beta-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-GinsenosideReUNII-46F3R0BL3Ipanaxsaponin Reinsenoside REEINECS 257-814-6Ginsenoside B2; Panaxoside Re; Sanchinoside Re(20S)-ginsenoside Re20(S)-ginsenoside ReGinsenoside B2(Standard)HY-N0044RWLZ4722

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External database identifiers

ChEBI:CHEBI:77148
ChEMBL:CHEMBL510095
EPA DTXSID:DTXSID801317298
PubMed:39798073
PubMed:37308051
PubMed:36682417
PubMed:29467000
PubMed:29037473
PubMed:25523949
PubMed:25297453
PubMed:24781185
PubMed:24709919
PubMed:24658813
PubMed:24615935
PubMed:24599032

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

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Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal US EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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