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InventoryRef 9722221/10/2019

GINSENOSIDE RE

Ginsenoside B2,\b-D-Glucopyranoside, (3.\b.,6.\a.,12.\b.)-20-(.\b.-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-(6-deoxy-.\a.-L-mannopyranosyl)-

GINSENOSIDE RE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Chemical identity and properties

PubChem 2D chemical structure for CAS 52286-59-6
CAS 52286-59-6PubChem CID 441921

Ginsenoside Re

Ginsenoside Re is a ginsenoside found in Panax ginseng that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 6 and 20 have been converted to the corresponding alpha-L-rhamnopyranosyl-(12)-beta-D-glucopyranoside and beta-D-glucopyranoside respectively, and in which a double bond has been introduced at the 24-25 position. It has a role as an antioxidant, an antineoplastic agent, a neuroprotective agent, an anti-inflammatory agent, a nephroprotective agent and a plant metabolite. It is a 3beta-hydroxy-4,4-dimethylsteroid, a beta-D-glucoside, a tetracyclic triterpenoid, a 3beta-hydroxy steroid, a 12beta-hydroxy steroid, a disaccharide derivative and a ginsenoside. It derives from a hydride of a dammarane. ChEBI

IUPAC name
(2S,3R,4R,5R,6S)-2-[(2R,3R,4S,5S,6R)-2-[[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-dihydroxy-4,4,8,10,14-pentamethyl-17-[(2S)-6-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhept-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6-yl]oxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-6-methyloxane-3,4,5-triol
Molecular formula
C48H82O18
Molecular weight
947.2 g/mol
Exact mass
946.55011576 Da
XLogP3
1.6
Topological polar surface area
298.0 Ų
Hydrogen-bond donors
12
Hydrogen-bond acceptors
18
Covalent units
1
Defined stereocentres
26

Also known as

Ginsenoside B2Panaxoside REginsenoside-ReSanchinoside ReNSC 308877NSC-30887746F3R0BL3ICHEBI:77148
16 more reported names
RefChem:37695Chikusetsusaponin IVcGinsenoside Re (Standard)b-D-Glucopyranoside,(3b,6a,12b)-20-(b-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-(6-deoxy-a-L-mannopyranosyl)-beta-D-Glucopyranoside, (3beta,6alpha,12beta)-20-(beta-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-GinsenosideReUNII-46F3R0BL3Ipanaxsaponin Reinsenoside REEINECS 257-814-6Ginsenoside B2; Panaxoside Re; Sanchinoside Re(20S)-ginsenoside Re20(S)-ginsenoside ReGinsenoside B2(Standard)HY-N0044RWLZ4722
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for GINSENOSIDE RE

INCI name

GINSENOSIDE RE

Description

Ginsenoside B2,\b-D-Glucopyranoside, (3.\b.,6.\a.,12.\b.)-20-(.\b.-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-(6-deoxy-.\a.-L-mannopyranosyl)-

Record provenance

Inventory reference
97222
Imported identity
GINSENOSIDE RE
Source update
21/10/2019
European Commission CosIng source notes

Key data

EC
Restriction
Function
ANTIOXIDANT
Inhibiting reactions promoted by oxygen, thus avoiding oxidation and rancidity.
HUMECTANT
Retaining and/or preserving the moisture in a product during use.
SKIN CONDITIONING
Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How GINSENOSIDE RE appears in the CosIng inventory

The CosIng inventory lists GINSENOSIDE RE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

GINSENOSIDE RE is also tagged with 3 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

GINSENOSIDE RE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, GINSENOSIDE RE carries the following function designation(s):

CAS 52286-59-6 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for GINSENOSIDE RE

This page reproduces the CosIng inventory entry for GINSENOSIDE RE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research GINSENOSIDE RE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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