Official EU label nameGlossary entry 10958

GINSENOSIDE RD

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

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Resolved identifiers

Resolved substance identity

CAS:52705-93-8

EC:258-118-5

Ingredient index records:

GINSENOSIDE RD

Cosmetic functions: ANTIOXIDANT

\b-D-Glucopyranoside, (3.b\b.,12.\b)-20-(\b-D-glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl 2-O-\b- D-glucopyranosyl-

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1 matched or reported name

GINSENOSIDE RD

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name GINSENOSIDE RD.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 52705-93-8

CAS 52705-93-8PubChem CID 11679800

Ginsenoside Rd

Ginsenoside Rd is a ginsenoside found in Panax ginseng and Panax japonicus var. major that is (20S)-ginsenoside Rg3 in which the hydroxy group at position 20 has been converted to its beta-D-glucopyranoside. It has a role as an anti-inflammatory drug, an immunosuppressive agent, a neuroprotective agent, an apoptosis inducer, a vulnerary and a plant metabolite. It is a beta-D-glucoside, a tetracyclic triterpenoid and a ginsenoside. It is functionally related to a (20S)-ginsenoside Rg3. — ChEBI

IUPAC name: (2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-4,4,8,10,14-pentamethyl-17-[(2S)-6-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhept-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol

Molecular formula: C48H82O18
Molecular weight: 947.2 g/mol
Exact mass: 946.55011576 Da
XLogP3: 2.4
Topological polar surface area: 298.0 Å²
Hydrogen-bond donors: 12
Hydrogen-bond acceptors: 18
Covalent units: 1
Defined stereocentres: 25

Also known as

Gypenoside VIIIChikusetsusaponin fk7WB232T95AVCHEBI:679882-O-beta-D-Glucopyranosyl-(3beta,12beta)-20-(beta-D-glucopyranosyloxy)-12-hydroxydammara-24-en-3-yl-beta-D-glucopyranosidebeta-D-Glucopyranoside, (3beta,12beta)-20-(beta-D-glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl 2-O-beta-D-glucopyranosyl-(3beta,12beta)-20-(beta-D-glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranosideRefChem:37442

16 more reported names

UNII-WB232T95AVGINSENOSIDE RD (CONSTITUENT OF AMERICAN GINSENG, ASIAN GINSENG, AND TIENCHI GINSENG)258-118-5ginsenoside-RdNSC-308876GS-RdG-Rd(20S)-ginsenoside Rd20(S)-ginsenoside RdGinsenoside Rd (Standard)(GS)-RdGypenoside VIII (Standard)HMS3885A14HY-N0043EINECS 258-118-5CCG-270588

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External database identifiers

ChEBI:CHEBI:67988
ChEMBL:CHEMBL473659
EPA DTXSID:DTXSID301031221
PubMed:30545933
PubMed:26111763
PubMed:25297453
PubMed:24781185
PubMed:24599032
PubMed:10571242
PubMed:9933756
PubMed:8988629

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

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Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal US EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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