Chloramine-T
Tosylchloramide sodium (INN)
Chloramine-T is listed in Annex III and may only be used under the conditions shown in this record. Maximum concentration in this record: 0.2%.
Chemical identity and properties
Chloramine-T
Chloramine T is an organic sodium salt derivative of toluene-4-sulfonamide with a chloro substituent in place of an amino hydrogen. It has a role as a disinfectant, an allergen and an antifouling biocide. It contains a chloro(p-tolylsulfonyl)azanide. — ChEBI
- IUPAC name
- sodium chloro-(4-methylphenyl)sulfonylazanide
- Molecular formula
- C7H7ClNNaO2S
- Molecular weight
- 227.64 g/mol
- Exact mass
- 226.9783716 Da
- Topological polar surface area
- 43.5 Ų
- Hydrogen-bond donors
- 0
- Hydrogen-bond acceptors
- 3
- Covalent units
- 2
- Defined stereocentres
- 0
Also known as
16 more reported names
External database identifiers
- ChEBI:CHEBI:53767
- ChEMBL:CHEMBL1697734
- EPA DTXSID:DTXSID6040321
Evidence from additional scientific databases
NIH PubChem PUG-View
Attributed physical-property, hazard, environmental and use annotations.
- Color/Form: White or slightly yellow crystals or crystalline powder Source: Hazardous Substances Data Bank (HSDB)
- Density: Density (trihydrate): 1.4 g/cm³ Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Flash Point: 192 °C c.c. (trihydrate) Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- LogP: log Kow = 0.84 /Estimated/ Source: Hazardous Substances Data Bank (HSDB)
- LogP: 0.84 (estimated) Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Melting Point: 170-177 °C decomposes Source: Hazardous Substances Data Bank (HSDB)
- Odor: Slight odor of chlorine Source: Hazardous Substances Data Bank (HSDB)
- Physical Description: CBI Source: EPA Chemical Data Reporting (CDR)
- Physical Description: White or slightly yellow crystals or crystalline powder; [HSDB] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Physical Description: WHITE SOLID IN VARIOUS FORMS WITH CHARACTERISTIC ODOUR. Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Solubility: Insoluble in benzene, chloroform, and ether; decomposed by alcohol Source: Hazardous Substances Data Bank (HSDB)
- Solubility: Soluble in water. Source: Hazardous Substances Data Bank (HSDB)
- Solubility: Solubility in water, g/100ml at 25 °C: (good, trihydrate) Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Exposure Routes: The substance can be absorbed into the body by inhalation of its aerosol and by ingestion. Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Signal: Danger Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
- GHS Hazard Statements: H302: Harmful if swallowed [Warning Acute toxicity, oral]; H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]; H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory] Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
- Precautionary Statement Codes: P233, P260, P264, P270, P271, P280, P284, P301+P317, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P321, P330, P342+P316, P363, P403, P405, and P501 (click each P-code to see the statement) Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
- Signal: Danger Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]; H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]; H317 (34.9%): May cause an allergic skin reaction [Warning Sensitization, Skin]; H318 (34.9%): Causes serious eye damage [Danger Serious eye damage/eye irritation]; H334 (100%): May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P233, P260, P261, P264, P264+P265, P270, P271, P272, P280, P284, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P330, P333+P317, P342+P316, P362+P364, P363, P403, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 298 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- Signal: Danger Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
- GHS Hazard Statements: H302: Harmful if swallowed [Warning Acute toxicity, oral]; H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]; H317: May cause an allergic skin reaction [Warning Sensitization, Skin]; H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory] Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
- Precautionary Statement Codes: P233, P260, P261, P264, P270, P271, P272, P280, P284, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P321, P330, P333+P317, P342+P316, P362+P364, P363, P403, P405, and P501 (click each P-code to see the statement) Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
- Consumer Uses: Other Source: EPA Chemical Data Reporting (CDR)
- Industry Uses: Preservative Source: EPA Chemical Data Reporting (CDR)
- Sources/Uses: Occupational asthma reported in janitors, brewery workers, and chemical workers; [Malo] Allergic contact dermatitis in housekeeping workers; [Marks] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Industrial Processes with risk of exposure: Using Disinfectants or Biocides [Category: Clean] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Uses: For chloramine t (USEPA/OPP Pesticide Code: 076502) there are 0 labels match. /SRP: Not registered for current use in the U.S., but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses./ Source: Hazardous Substances Data Bank (HSDB)
- Uses: Detection of bromate and halogens; antibacterial; VET: antiseptic (topical). Source: Hazardous Substances Data Bank (HSDB)
- Uses: Antiseptic /Trihydrate/ Source: Hazardous Substances Data Bank (HSDB)
- Uses: Chloramines are no longer employed for irrigation of wounds... but are used in the emergency sterilization of drinking water and for sanitization. /Chloramines/ Source: Hazardous Substances Data Bank (HSDB)
- Uses: Tosylchloramide sodium is an organic chlorine compound with an available chlorine content of 28-30% and is intended for use in fish farming for prevention and control of bacterial gill disease. Source: Hazardous Substances Data Bank (HSDB)
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Record details
Maximum concentration
0.2%
INCI glossary name
Chloramine-T
Chemical name
Tosylchloramide sodium (INN)
Chemical / IUPAC name
Benzenesulfonamide, N-chloro-4-methyl-, sodium salt (1:1)
Regulatory information
Identified ingredients
Key data
Inventory links for Chloramine-T
Related records for Chloramine-T
Direct matches are limited for this record, so nearby entries from Annex III are shown as well.
AMMONIA
POTASSIUM CHLORATE / SODIUM CHLORATE
p-Phenylenediamine and its salts
p-Phenylenediamine; p-Phenylenediamine HCl; p-Phenylenediamine Sulphate
N,N'-BIS(2-HYDROXYETHYL)-2-NITRO-P-PHENYLENEDIAMINE
N-substituted derivatives of p- Phenylenediamine and their salts; N- substituted derivatives of o-P…
Toluene-2,5-diamine Toluene-2,5-diamine sulphate
2,6-Dihydroxyethylaminotoluene
Methylphenylenediamines, their N-substituted derivatives and their salts (1) with the exception of …
What Annex III means for Chloramine-T
Chloramine-T is a restricted substance under Annex III of EU Cosmetics Regulation 1223/2009. Its use in cosmetics is only permitted under the specific conditions set out in the entry above, including applicable concentration limits, product type restrictions and required warning statements.
When including this substance in a formulation, all conditions — maximum concentration, product scope and warning labels — must be met simultaneously. Compliance with one condition does not override the others.
This record is linked to 1 CosIng inventory ingredient for name and identifier cross-reference. The page also surfaces 12 related annex records with overlapping identifiers, annex logic or naming patterns.
Compliance checklist
- Ensure formulation concentration does not exceed: 0.2%
- Document conditions of use in the Product Information File (PIF).
Frequently asked questions
Source note for Annex III record Chloramine-T
This page summarizes one Annex III record for Chloramine-T from public European Commission cosmetic materials and adds linked inventory or identifier matches when available.
Use this record page to review Annex III conditions for Chloramine-T, but confirm any final regulatory decision against the current official annex wording and source files.
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