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Annex II Entry 1461 CMR30/07/2020

Nickel(II) sulfite [1]; Nickel tellurium trioxide [2]; Nickel tellurium tetraoxide [3]; Molybdenum nickel hydroxide oxide phosphate [4]

Nickel(II) sulfite [1]; Nickel tellurium trioxide [2]; Nickel tellurium tetraoxide [3]; Molybdenum nickel hydroxide oxide phosphate [4] is listed in Annex II as a prohibited substance for cosmetic products placed on the EU market.

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Prohibited substance— Annex II, EU Regulation 1223/2009
Entry: 1461
CMR

Chemical identity and properties

PubChem 2D chemical structure for CAS 15851-52-2
CAS 15851-52-2PubChem CID 167478

Telluric acid (H2TeO3), nickel(2+) salt (1:1)

IUPAC name
nickel(2+) tellurite
Molecular formula
NiO3Te
Molecular weight
234.3 g/mol
Exact mass
235.826308 Da
Topological polar surface area
63.2 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
3
Covalent units
2
Defined stereocentres
0

Also known as

Nickel telluriteEINECS 239-967-0RefChem:187761Nickel tellurium trioxideCMLGVHIYOLIDTE-UHFFFAOYSA-L
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External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 15852-21-8
CAS 15852-21-8PubChem CID 167483

Telluric acid (H2TeO4), nickel(2+) salt (1:1)

IUPAC name
nickel(2+) tellurate
Molecular formula
NiO4Te
Molecular weight
250.3 g/mol
Exact mass
251.821223 Da
Topological polar surface area
80.3 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
4
Covalent units
2
Defined stereocentres
0

Also known as

Nickel tellurateEINECS 239-974-9RefChem:187765Nickel tellurium tetraoxideJWTUERYYWTZBJA-UHFFFAOYSA-L
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 68130-36-9
CAS 68130-36-9PubChem CID 176236

Molybdenum nickel hydroxide oxide phosphate

IUPAC name
molybdenum;nickel(2+);oxygen(2-);hydroxide;phosphate
Molecular formula
HMoNiO6P-4
Molecular weight
282.62 g/mol
Exact mass
283.791820 Da
Topological polar surface area
88.3 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
6
Covalent units
5
Defined stereocentres
0

Also known as

EINECS 268-585-7RefChem:819151268-585-7KNQDGGOTQNRXGB-UHFFFAOYSA-J
Open full PubChem recordPubChem annotations3D structure image

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 7757-95-1
CAS 7757-95-1PubChem CID 14029754

Nickel sulfite

IUPAC name
nickel(2+) sulfite
Molecular formula
NiO3S
Molecular weight
138.76 g/mol
Exact mass
137.892157 Da
Topological polar surface area
82.4 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
4
Covalent units
2
Defined stereocentres
0

Also known as

8Q3P3VGJ6TRefChem:165684231-827-7nickel(II) sulfitenickel(2+);sulfiteNickel(2+) sulphiteEINECS 231-827-7Nickel sulfite (NiSO3)
1 more reported name
LONQOCRNVIZRSA-UHFFFAOYSA-L
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Record details

Chemical name

Nickel(II) sulfite [1]; Nickel tellurium trioxide [2]; Nickel tellurium tetraoxide [3]; Molybdenum nickel hydroxide oxide phosphate [4]

Chemical / IUPAC name

Nickel(II) sulfite [1]; Nickel tellurium trioxide [2]; Nickel tellurium tetraoxide [3]; Molybdenum nickel hydroxide oxide phosphate [4]

Regulatory information

Regulation

(EU) 2019/831

See every entry this act set

CMR

CategoryCarcinogenicMutagenicReprotoxic
Cat. 1A✓——

Key data

CAS
7757-95-1 [1] / 15851-52-2 [2] / 15852-21-8 [3] / 68130-36-9 [4]
EC
231-827-7 [1] / 239-967-0 [2] / 239-974-9 [3] / 268-585-7 [4]
Annex
II
Entry number
1461

Direct matches are limited for this record, so nearby entries from Annex II are shown as well.

Annex II 1460
Nearby record in the same annex

Nickel(II) trifluoroacetate; [1] Nickel(II) propionate; [2] Nickel bis(benzenesulfonate); [3] Nicke…

CAS: 16083-14-0 [1] 3349-08-4 [2] 39819-65-3 [3] 18721-51-2 [4] 18283-82-4 [5] 22605-92-1 [6] 4454-16-4 [7] 7580-31-6 [8] 93983-68-7 [9] 29317-63-3 [10] 27637-46-3 [11] 84852-37-9 [12] 93920-10-6 [13] 85508-43-6 [14] 85508-44-7 [15] 51818-56-5 [16] 93920-
EC: 240-235-8 [1] 222-102-6 [2] 254-642-3 [3] 242-533-3 [4] 242-161-1 [5] 245-119-0 [6] 224-699-9 [7] 231-480-1 [8] 301-323-2 [9] 249-555-2 [10] 248-585-3 [11] 284-349-6 [12] 300-094-6 [13] 287-468-1 [14] 287-469-7 [15] 257-447-1 [16] 300-093-0 [17] 276-
Annex II 1463
Nearby record in the same annex

Dialuminium nickel tetraoxide [1]; Nickel titanium trioxide [2]; Nickel titanium oxide [3]; Nickel …

CAS: 12004-35-2 [1] / 12035-39-1 [2] / 12653-76-8 [3] / 52502-12-2 [4] / 68016-03-5 [5] / 70692-93-2 [6] / 14177-55-0 [7] / 14177-51-6 [8] / 68515-84-4 [9] / 12031-65-1 [10] / 12673-58-4 [11]
EC: 234-454-8 [1] / 234-825-4 [2] / 235-752-0 [3] / 257-970-5 [4] / 268-169-5 [5] / 274-755-1 [6] / 238-034-5 [7] / 238-032-4 [8] / 271-112-7 [9] / - [10] / - [11]
Annex II 1455
Nearby record in the same annex

Nickel selenide

CAS: 1314-05-2
EC: 215-216-2

What Annex II means for Nickel(II) sulfite [1]; Nickel tellurium trioxide [2]; Nickel tellurium tetraoxide [3]; Molybdenum nickel hydroxide oxide phosphate [4]

Nickel(II) sulfite [1]; Nickel tellurium trioxide [2]; Nickel tellurium tetraoxide [3]; Molybdenum nickel hydroxide oxide phosphate [4] is listed as a prohibited substance under Annex II of EU Cosmetics Regulation 1223/2009 and must not be intentionally added. Article 17 separately addresses unintended small quantities that are technically unavoidable under good manufacturing practice and compatible with the Article 3 safety requirement.

Formulators must screen their ingredients and raw materials to ensure none contain this substance. Suppliers should provide documentation confirming absence when requested.

The page also surfaces 12 related annex records with overlapping identifiers, annex logic or naming patterns.

Compliance checklist

  • Verify this substance is absent from all raw materials and finished formulations.
  • Request absence confirmation or CoA from raw material suppliers.
  • Document the screening result in the Product Information File (PIF).
  • This substance has CMR classification. Review the CMR table above and verify current Annex II/III status before use.

Frequently asked questions

Yes. Nickel(II) sulfite [1]; Nickel tellurium trioxide [2]; Nickel tellurium tetraoxide [3]; Molybdenum nickel hydroxide oxide phosphate [4] is listed in Annex II of EU Cosmetics Regulation 1223/2009 and is prohibited as an intentionally added cosmetic ingredient. Article 17 provides a narrow exception for unintended small quantities that are technically unavoidable under good manufacturing practice, provided the product remains safe under Article 3.

CAS 7757-95-1 [1] / 15851-52-2 [2] / 15852-21-8 [3] / 68130-36-9 [4] is the unique numerical identifier assigned to Nickel(II) sulfite [1]; Nickel tellurium trioxide [2]; Nickel tellurium tetraoxide [3]; Molybdenum nickel hydroxide oxide phosphate [4] by the Chemical Abstracts Service. In cosmetic compliance work, the CAS number is used to cross-reference the substance across regulatory databases, raw material specifications and safety assessment reports. Multiple EU annex entries may share the same CAS number if the same substance appears under different conditions or in different annexes.

Nickel(II) sulfite [1]; Nickel tellurium trioxide [2]; Nickel tellurium tetraoxide [3]; Molybdenum nickel hydroxide oxide phosphate [4] has a CMR (carcinogenic, mutagenic or reprotoxic) classification under EU CLP Regulation. Under Article 15 of EU Cosmetics Regulation 1223/2009, CMR substances of category 1A or 1B are prohibited in cosmetics unless specifically permitted. Category 2 CMR substances may be used only if assessed safe by the SCCS. Always verify current annex status and any applicable derogations before use.

Use the INCI Checker tool on this site to paste your full ingredient list (INCI) and scan it against all Annex II–VI entries. The tool highlights any ingredients that match restricted, prohibited or allergen-flagged records. This is useful for rapid compliance screening of finished product formulas or raw material declarations.
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Source note for Annex II record Nickel(II) sulfite [1]; Nickel tellurium trioxide [2]; Nickel tellurium tetraoxide [3]; Molybdenum nickel hydroxide oxide phosphate [4]

This page summarizes one Annex II record for Nickel(II) sulfite [1]; Nickel tellurium trioxide [2]; Nickel tellurium tetraoxide [3]; Molybdenum nickel hydroxide oxide phosphate [4] from public European Commission cosmetic materials and adds linked inventory or identifier matches when available.

Use this record page to review Annex II conditions for Nickel(II) sulfite [1]; Nickel tellurium trioxide [2]; Nickel tellurium tetraoxide [3]; Molybdenum nickel hydroxide oxide phosphate [4], but confirm any final regulatory decision against the current official annex wording and source files.

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