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Annex II Entry 1459 CMR30/07/2020

Nickel dichlorate [1]; Nickel dibromate [2]; Ethyl hydrogen sulfate, nickel(II) salt [3]

Nickel dichlorate [1]; Nickel dibromate [2]; Ethyl hydrogen sulfate, nickel(II) salt [3] is listed in Annex II as a prohibited substance for cosmetic products placed on the EU market.

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Prohibited substance— Annex II, EU Regulation 1223/2009
Entry: 1459
CMR

Chemical identity and properties

PubChem 2D chemical structure for CAS 14550-87-9
CAS 14550-87-9PubChem CID 167113

Hexaaquanickel(II) bromate

IUPAC name
nickel(2+) dibromate
Molecular formula
Br2NiO6
Molecular weight
314.50 g/mol
Exact mass
313.73946 Da
Topological polar surface area
114.0 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
6
Covalent units
3
Defined stereocentres
0

Also known as

RefChem:145897Nickel dibromateNickel bromatenickel(2+);dibromateEINECS 238-596-1Bromic acid, nickel(2+) saltXCCVZTSVSXTDDO-UHFFFAOYSA-L
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External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 67952-43-6
CAS 67952-43-6PubChem CID 162212

Chloric acid, nickel(2+) salt (2:1)

IUPAC name
nickel(2+) dichlorate
Molecular formula
Cl2NiO6
Molecular weight
225.59 g/mol
Exact mass
223.842535 Da
Topological polar surface area
114.0 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
6
Covalent units
3
Defined stereocentres
0

Also known as

RefChem:125317Nickel chlorateChloric acid, nickel(2+) saltNickel dichlorateHexaaquanickel(II) chlorateEINECS 267-897-0HAN(II)RZLUIDROFNIMHF-UHFFFAOYSA-L
1 more reported name
NSC 74401
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External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 71720-48-4
CAS 71720-48-4PubChem CID 56843838

ethyl hydrogen sulphate, nickel(2+) salt

IUPAC name
ethyl sulfate;nickel(2+)
Molecular formula
C4H10NiO8S2
Molecular weight
308.9 g/mol
Exact mass
307.917051 Da
Topological polar surface area
150.0 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
8
Covalent units
3
Defined stereocentres
0

Also known as

EINECS 275-897-7RefChem:596219275-897-7Nickel(2+) bis(ethyl sulfate)RCTDJXBPXBKJTD-UHFFFAOYSA-L
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External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Record details

Chemical name

Nickel dichlorate [1]; Nickel dibromate [2]; Ethyl hydrogen sulfate, nickel(II) salt [3]

Chemical / IUPAC name

Nickel dichlorate [1]; Nickel dibromate [2]; Ethyl hydrogen sulfate, nickel(II) salt [3]

Regulatory information

Regulation

(EU) 2019/831

See every entry this act set

CMR

CategoryCarcinogenicMutagenicReprotoxic
Cat. 1B✓—✓
Cat. 2—✓—

Key data

CAS
67952-43-6 [1] 14550-87-9 [2] 71720-48-4 [3]
EC
267-897-0 [1] 238-596-1 [2] 275-897-7 [3]
Annex
II
Entry number
1459

Direct matches are limited for this record, so nearby entries from Annex II are shown as well.

Annex II 1460
Nearby record in the same annex

Nickel(II) trifluoroacetate; [1] Nickel(II) propionate; [2] Nickel bis(benzenesulfonate); [3] Nicke…

CAS: 16083-14-0 [1] 3349-08-4 [2] 39819-65-3 [3] 18721-51-2 [4] 18283-82-4 [5] 22605-92-1 [6] 4454-16-4 [7] 7580-31-6 [8] 93983-68-7 [9] 29317-63-3 [10] 27637-46-3 [11] 84852-37-9 [12] 93920-10-6 [13] 85508-43-6 [14] 85508-44-7 [15] 51818-56-5 [16] 93920-
EC: 240-235-8 [1] 222-102-6 [2] 254-642-3 [3] 242-533-3 [4] 242-161-1 [5] 245-119-0 [6] 224-699-9 [7] 231-480-1 [8] 301-323-2 [9] 249-555-2 [10] 248-585-3 [11] 284-349-6 [12] 300-094-6 [13] 287-468-1 [14] 287-469-7 [15] 257-447-1 [16] 300-093-0 [17] 276-
Annex II 1455
Nearby record in the same annex

Nickel selenide

CAS: 1314-05-2
EC: 215-216-2
Annex II 1463
Nearby record in the same annex

Dialuminium nickel tetraoxide [1]; Nickel titanium trioxide [2]; Nickel titanium oxide [3]; Nickel …

CAS: 12004-35-2 [1] / 12035-39-1 [2] / 12653-76-8 [3] / 52502-12-2 [4] / 68016-03-5 [5] / 70692-93-2 [6] / 14177-55-0 [7] / 14177-51-6 [8] / 68515-84-4 [9] / 12031-65-1 [10] / 12673-58-4 [11]
EC: 234-454-8 [1] / 234-825-4 [2] / 235-752-0 [3] / 257-970-5 [4] / 268-169-5 [5] / 274-755-1 [6] / 238-034-5 [7] / 238-032-4 [8] / 271-112-7 [9] / - [10] / - [11]

What Annex II means for Nickel dichlorate [1]; Nickel dibromate [2]; Ethyl hydrogen sulfate, nickel(II) salt [3]

Nickel dichlorate [1]; Nickel dibromate [2]; Ethyl hydrogen sulfate, nickel(II) salt [3] is listed as a prohibited substance under Annex II of EU Cosmetics Regulation 1223/2009 and must not be intentionally added. Article 17 separately addresses unintended small quantities that are technically unavoidable under good manufacturing practice and compatible with the Article 3 safety requirement.

Formulators must screen their ingredients and raw materials to ensure none contain this substance. Suppliers should provide documentation confirming absence when requested.

The page also surfaces 12 related annex records with overlapping identifiers, annex logic or naming patterns.

Compliance checklist

  • Verify this substance is absent from all raw materials and finished formulations.
  • Request absence confirmation or CoA from raw material suppliers.
  • Document the screening result in the Product Information File (PIF).
  • This substance has CMR classification. Review the CMR table above and verify current Annex II/III status before use.

Frequently asked questions

Yes. Nickel dichlorate [1]; Nickel dibromate [2]; Ethyl hydrogen sulfate, nickel(II) salt [3] is listed in Annex II of EU Cosmetics Regulation 1223/2009 and is prohibited as an intentionally added cosmetic ingredient. Article 17 provides a narrow exception for unintended small quantities that are technically unavoidable under good manufacturing practice, provided the product remains safe under Article 3.

CAS 67952-43-6 [1] 14550-87-9 [2] 71720-48-4 [3] is the unique numerical identifier assigned to Nickel dichlorate [1]; Nickel dibromate [2]; Ethyl hydrogen sulfate, nickel(II) salt [3] by the Chemical Abstracts Service. In cosmetic compliance work, the CAS number is used to cross-reference the substance across regulatory databases, raw material specifications and safety assessment reports. Multiple EU annex entries may share the same CAS number if the same substance appears under different conditions or in different annexes.

Nickel dichlorate [1]; Nickel dibromate [2]; Ethyl hydrogen sulfate, nickel(II) salt [3] has a CMR (carcinogenic, mutagenic or reprotoxic) classification under EU CLP Regulation. Under Article 15 of EU Cosmetics Regulation 1223/2009, CMR substances of category 1A or 1B are prohibited in cosmetics unless specifically permitted. Category 2 CMR substances may be used only if assessed safe by the SCCS. Always verify current annex status and any applicable derogations before use.

Use the INCI Checker tool on this site to paste your full ingredient list (INCI) and scan it against all Annex II–VI entries. The tool highlights any ingredients that match restricted, prohibited or allergen-flagged records. This is useful for rapid compliance screening of finished product formulas or raw material declarations.
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Source note for Annex II record Nickel dichlorate [1]; Nickel dibromate [2]; Ethyl hydrogen sulfate, nickel(II) salt [3]

This page summarizes one Annex II record for Nickel dichlorate [1]; Nickel dibromate [2]; Ethyl hydrogen sulfate, nickel(II) salt [3] from public European Commission cosmetic materials and adds linked inventory or identifier matches when available.

Use this record page to review Annex II conditions for Nickel dichlorate [1]; Nickel dibromate [2]; Ethyl hydrogen sulfate, nickel(II) salt [3], but confirm any final regulatory decision against the current official annex wording and source files.

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