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Annex II Entry 1460 30/07/2020

Nickel(II) trifluoroacetate; [1] Nickel(II) propionate; [2] Nickel bis(benzenesulfonate); [3] Nickel(II) hydrogen citrate; [4] Citric acid, ammonium nickel salt; [5] Citric acid, nickel salt; [6] Nickel bis(2-ethylhexanoate); [7] 2-Ethylhexanoic acid, Nickel salt; [8] Dimethylhexanoic acid nickel salt; [9] Nickel(II) isooctanoate; [10] Nickel isooctanoate; [11] Nickel bis(isononanoate); [12] Nickel(II) neononanoate; [13] Nickel(II) isodecanoate; [14] Nickel(II) neodecanoate; [15] Neodecanoic acid, nickel salt; [16] Nickel(II) neoundecanoate; [17] Bis(D-gluconato-O1,O2)nickel; [18] Nickel 3,5-bis(tert-butyl)-4-hydroxybenzoate (1:2); [19] Nickel(II) palmitate; [20] (2-Ethylhexanoato-O)(Isononanoato-O)nickel; [21] (Isononanoato-O)(Isooctanoato-O)nickel; [22] (Isooctanoato-O)(neodecanoato-O)nickel; [23] (2-Ethylhexanoato-O)(Isodecanoato-O)nickel; [24] (2-Ethylhexanoato-O)(Neodecanoato-O)nickel; [25] (Isodecanoato-O)(isooctanoato-O)nickel; [26] (Isodecanoato-O)(isononanoato-O)nickel; [27] (Isononanoato-O)(Neodecanoato-O)nickel; [28] fatty acids, C6-19-branched, nickel salts; [29] fatty acids, C8-18 and C18-unsaturated, nickel salts; [30] 2,7-Naphthalenedisulfonic acid, nickel(II) salt; [31]

Nickel(II) trifluoroacetate; [1] Nickel(II) propionate; [2] Nickel bis(benzenesulfonate); [3] Nickel(II) hydrogen citrate; [4] Citric acid, ammonium nickel salt; [5] Citric acid, nickel salt; [6] Nickel bis(2-ethylhexanoate); [7] 2-Ethylhexanoic acid, Nickel salt; [8] Dimethylhexanoic acid nickel salt; [9] Nickel(II) isooctanoate; [10] Nickel isooctanoate; [11] Nickel bis(isononanoate); [12] Nickel(II) neononanoate; [13] Nickel(II) isodecanoate; [14] Nickel(II) neodecanoate; [15] Neodecanoic acid, nickel salt; [16] Nickel(II) neoundecanoate; [17] Bis(D-gluconato-O1,O2)nickel; [18] Nickel 3,5-bis(tert-butyl)-4-hydroxybenzoate (1:2); [19] Nickel(II) palmitate; [20] (2-Ethylhexanoato-O)(Isononanoato-O)nickel; [21] (Isononanoato-O)(Isooctanoato-O)nickel; [22] (Isooctanoato-O)(neodecanoato-O)nickel; [23] (2-Ethylhexanoato-O)(Isodecanoato-O)nickel; [24] (2-Ethylhexanoato-O)(Neodecanoato-O)nickel; [25] (Isodecanoato-O)(isooctanoato-O)nickel; [26] (Isodecanoato-O)(isononanoato-O)nickel; [27] (Isononanoato-O)(Neodecanoato-O)nickel; [28] fatty acids, C6-19-branched, nickel salts; [29] fatty acids, C8-18 and C18-unsaturated, nickel salts; [30] 2,7-Naphthalenedisulfonic acid, nickel(II) salt; [31] is listed in Annex II as a prohibited substance for cosmetic products placed on the EU market.

Prohibited substance— Annex II, EU Regulation 1223/2009
Entry: 1460

Chemical identity and properties

PubChem 2D chemical structure for CAS 16083-14-0
CAS 16083-14-0PubChem CID 14574678

Nickel(2+) trifluoroacetate

IUPAC name
nickel(2+);bis(2,2,2-trifluoroacetate)
Molecular formula
C4F6NiO4
Molecular weight
284.72 g/mol
Exact mass
283.905419 Da
Topological polar surface area
80.3 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
10
Covalent units
3
Defined stereocentres
0

Also known as

EINECS 240-235-8AI3-26112NICKEL(II) TRIFLUOROACETATEAcetic acid, trifluoro-, nickel(2+) saltRefChem:853929240-235-8nickel(2+);2,2,2-trifluoroacetateNickel(2+) Bis(Trifluoroacetate)
6 more reported names
Nickel(II) 2,2,2-trifluoroacetateC4F6NiO4nickelous;2,2,2-trifluoroacetateVBLNFWKVZVKXPH-UHFFFAOYSA-LDB-221633Acetic acid, 2,2,2-trifluoro-, nickel(2+) salt (2:1)?
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 18283-82-4
CAS 18283-82-4PubChem CID 172101

1,2,3-Propanetricarboxylic acid, 2-hydroxy-, ammonium nickel(2+) salt (2:2:1)

IUPAC name
azanium;2-hydroxypropane-1,2,3-tricarboxylate;nickel(2+)
Molecular formula
C6H9NNiO7
Molecular weight
265.83 g/mol
Exact mass
264.973243 Da
Topological polar surface area
142.0 Ų
Hydrogen-bond donors
2
Hydrogen-bond acceptors
7
Covalent units
3
Defined stereocentres
0

Also known as

Nickel diammonium dicitrateEINECS 242-161-1EINECS 268-176-3Citric acid, ammonium nickel saltRefChem:410691242-161-1Citric acid , ammonium nickel saltAmmonium nickel(2+) 2-hydroxypropane-1,2,3-tricarboxylate (1/1/1)
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 18721-51-2
CAS 18721-51-2PubChem CID 23615267

Nickel(2+) hydrogen citrate

IUPAC name
2-(carboxymethyl)-2-hydroxybutanedioate;nickel(2+)
Molecular formula
C6H6NiO7
Molecular weight
248.80 g/mol
Exact mass
247.946694 Da
Topological polar surface area
138.0 Ų
Hydrogen-bond donors
2
Hydrogen-bond acceptors
7
Covalent units
2
Defined stereocentres
0

Also known as

EINECS 242-533-3EC 242-533-3RefChem:165688242-533-3
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 22605-92-1
CAS 22605-92-1PubChem CID 14345053

citric acid, nickel salt

IUPAC name
2-hydroxypropane-1,2,3-tricarboxylate;nickel(3+)
Molecular formula
C6H5NiO7
Molecular weight
247.79 g/mol
Exact mass
246.938869 Da
Topological polar surface area
141.0 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
7
Covalent units
2
Defined stereocentres
0

Also known as

EINECS 245-119-0RefChem:577466EC 245-119-0245-119-0Citric acid nickel saltQTZURURAKNSDHT-UHFFFAOYSA-K

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 27637-46-3
CAS 27637-46-3PubChem CID 122361334

Nickel isooctanoate

IUPAC name
6-methylheptanoic acid;nickel(2+)
Molecular formula
C8H16NiO2+2
Molecular weight
202.90 g/mol
Exact mass
202.050371 Da
Topological polar surface area
37.3 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
2
Covalent units
2
Defined stereocentres
0

Also known as

EINECS 248-585-3RefChem:165672248-585-3

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 29317-63-3
CAS 29317-63-3PubChem CID 57376561

Nickel(II) isooctanoate

IUPAC name
bis(6-methylheptanoate);nickel(2+)
Molecular formula
C16H30NiO4
Molecular weight
345.10 g/mol
Exact mass
344.149751 Da
Topological polar surface area
80.3 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
4
Covalent units
3
Defined stereocentres
0

Also known as

EINECS 249-555-2RefChem:165696249-555-2HZDKXMGUAHPVDB-UHFFFAOYSA-LNickel(2+) bis(6-methylheptanoate)
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 3349-08-4
CAS 3349-08-4PubChem CID 13682635

Nickel(2+) propionate

Zinc proprionate is a chemical compound of zinc. Zinc is a metallic element with the atomic number 30. It is found in nature most often as the mineral sphalerite. Though excess zinc in harmful, in smaller amounts it is an essential element for life, as it is a cofactor for over 300 enzymes and is found in just as many transcription factors. (L48, L49) Toxin and Toxin Target Database (T3DB)

IUPAC name
nickel(2+);propanoate
Molecular formula
C6H10NiO4
Molecular weight
204.83 g/mol
Exact mass
203.993250 Da
Topological polar surface area
80.3 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
4
Covalent units
3
Defined stereocentres
0

Also known as

nickel(II) propionatePropanoic acid, nickel(2+) saltEINECS 222-102-6NSC 58969AI3-26111EC 222-102-6RefChem:853927222-102-6
1 more reported name
CIMSFRCJLLCURG-UHFFFAOYSA-L

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 39819-65-3
CAS 39819-65-3PubChem CID 14325094

Nickel bis(benzenesulphonate)

IUPAC name
benzenesulfonate;nickel(2+)
Molecular formula
C12H10NiO6S2
Molecular weight
373.0 g/mol
Exact mass
371.927222 Da
Topological polar surface area
131.0 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
6
Covalent units
3
Defined stereocentres
0

Also known as

EINECS 254-642-3RefChem:853840254-642-3Nickel(II) BenzenesulfonateBenzenesulfonic acid nickel saltnickel(ii) benzenesulfonate hexahydratenickelous;benzenesulfonateC12H10NiO6S2
3 more reported names
IBVWKDVFDAWRFU-UHFFFAOYSA-LBenzenesulfonic Acid Nickel(II) SaltB0034

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 4454-16-4
CAS 4454-16-4PubChem CID 107553

Nickel bis(2-ethylhexanoate)

IUPAC name
bis(2-ethylhexanoate);nickel(2+)
Molecular formula
C16H30NiO4
Molecular weight
345.10 g/mol
Exact mass
344.149751 Da
Topological polar surface area
80.3 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
4
Covalent units
3
Defined stereocentres
0

Also known as

EINECS 224-699-9EC 224-699-9RefChem:165657Hexanoic acid, 2ethyl, nickel(2+) salt224-699-9Nickel(II) 2-ethylhexanoate2-ethylhexanoate;nickel(2+)Hexanoic acid, 2-ethyl-, nickel(2+) salt
6 more reported names
Nickel(II) 2-ethylhexanoate, 78% in 2-ethylhexanoic acid (10-15% Ni)nickelous;2-ethylhexanoatenickel bis(2-ethyl hexanoate)nickel(2+) bis(2-ethylhexanoate)nickel(II) bis (2-ethylhexanoate)Hexanoic acid, 2-ethyl-, nickel(2+) salt (2:1)
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 7580-31-6
CAS 7580-31-6PubChem CID 24231

Hexanoic acid, 2-ethyl-, nickel salt (1:?)

IUPAC name
2-ethylhexanoic acid;nickel
Molecular formula
C8H16NiO2
Molecular weight
202.90 g/mol
Exact mass
202.050371 Da
Topological polar surface area
37.3 Ų
Hydrogen-bond donors
1
Hydrogen-bond acceptors
2
Covalent units
2
Defined stereocentres
0

Also known as

Nickel 2-ethylhexanoateEINECS 231-480-1Hexanoic acid, 2-ethyl-, nickel saltRefChem:1462022-Ethylhexanoic acid, nickel salt2-ethyl hexanoic acid nickel

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 84852-37-9
CAS 84852-37-9PubChem CID 174395

Isononanoic acid, nickel(2+) salt (2:1)

IUPAC name
bis(7-methyloctanoate);nickel(2+)
Molecular formula
C18H34NiO4
Molecular weight
373.2 g/mol
Exact mass
372.181051 Da
Topological polar surface area
80.3 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
4
Covalent units
3
Defined stereocentres
0

Also known as

EINECS 284-349-6Isononanoic acid, nickel(2+) saltRefChem:149601Nickel bis(isononanoate)

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 85508-43-6
CAS 85508-43-6PubChem CID 56842394

Nickel(II) isodecanoate

IUPAC name
bis(8-methylnonanoate);nickel(2+)
Molecular formula
C20H38NiO4
Molecular weight
401.2 g/mol
Exact mass
400.212351 Da
Topological polar surface area
80.3 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
4
Covalent units
3
Defined stereocentres
0

Also known as

EINECS 287-468-1RefChem:165695287-468-1RSWNZKSBWZHYGH-UHFFFAOYSA-LNickel(2+) bis(8-methylnonanoate)
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 85508-44-7
CAS 85508-44-7PubChem CID 171072

Neodecanoic acid, nickel salt (1:?)

IUPAC name
bis(7,7-dimethyloctanoate);nickel(2+)
Molecular formula
C20H38NiO4
Molecular weight
401.2 g/mol
Exact mass
400.212351 Da
Topological polar surface area
80.3 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
4
Covalent units
3
Defined stereocentres
0

Also known as

Nickel(2+) neodecanoateEINECS 287-469-7EINECS 257-447-1RefChem:832239287-469-7VNBCIRBFLBYHCW-UHFFFAOYSA-LNickel(2+) bis(7,7-dimethyloctanoate)
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 93920-10-6
CAS 93920-10-6PubChem CID 44146403

Nickel(2+) neononanoate

IUPAC name
bis(6,6-dimethylheptanoate);nickel(2+)
Molecular formula
C18H34NiO4
Molecular weight
373.2 g/mol
Exact mass
372.181051 Da
Topological polar surface area
80.3 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
4
Covalent units
3
Defined stereocentres
0

Also known as

EINECS 300-094-6KTILMTJXFBTZPK-UHFFFAOYSA-LNickel(2+) bis(6,6-dimethylheptanoate)
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 93983-68-7
CAS 93983-68-7PubChem CID 44145184

dimethylhexanoic acid, nickel salt

IUPAC name
bis(2,2-dimethylhexanoate);nickel(2+)
Molecular formula
C16H30NiO4
Molecular weight
345.10 g/mol
Exact mass
344.149751 Da
Topological polar surface area
80.3 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
4
Covalent units
3
Defined stereocentres
0

Also known as

EINECS 301-323-2RefChem:134355301-323-2FJOSQPRLIXFBGL-UHFFFAOYSA-LNickel(2+) bis(2,2-dimethylhexanoate)
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Record details

Chemical name

Nickel(II) trifluoroacetate; [1] Nickel(II) propionate; [2] Nickel bis(benzenesulfonate); [3] Nickel(II) hydrogen citrate; [4] Citric acid, ammonium nickel salt; [5] Citric acid, nickel salt; [6] Nickel bis(2-ethylhexanoate); [7] 2-Ethylhexanoic acid, Nickel salt; [8] Dimethylhexanoic acid nickel salt; [9] Nickel(II) isooctanoate; [10] Nickel isooctanoate; [11] Nickel bis(isononanoate); [12] Nickel(II) neononanoate; [13] Nickel(II) isodecanoate; [14] Nickel(II) neodecanoate; [15] Neodecanoic acid, nickel salt; [16] Nickel(II) neoundecanoate; [17] Bis(D-gluconato-O1,O2)nickel; [18] Nickel 3,5-bis(tert-butyl)-4-hydroxybenzoate (1:2); [19] Nickel(II) palmitate; [20] (2-Ethylhexanoato-O)(Isononanoato-O)nickel; [21] (Isononanoato-O)(Isooctanoato-O)nickel; [22] (Isooctanoato-O)(neodecanoato-O)nickel; [23] (2-Ethylhexanoato-O)(Isodecanoato-O)nickel; [24] (2-Ethylhexanoato-O)(Neodecanoato-O)nickel; [25] (Isodecanoato-O)(isooctanoato-O)nickel; [26] (Isodecanoato-O)(isononanoato-O)nickel; [27] (Isononanoato-O)(Neodecanoato-O)nickel; [28] fatty acids, C6-19-branched, nickel salts; [29] fatty acids, C8-18 and C18-unsaturated, nickel salts; [30] 2,7-Naphthalenedisulfonic acid, nickel(II) salt; [31]

Chemical / IUPAC name

Nickel(II) trifluoroacetate; [1] Nickel(II) propionate; [2] Nickel bis(benzenesulfonate); [3] Nickel(II) hydrogen citrate; [4] Citric acid, ammonium nickel salt; [5] Citric acid, nickel salt; [6] Nickel bis(2-ethylhexanoate); [7] 2-Ethylhexanoic acid, Nickel salt; [8] Dimethylhexanoic acid nickel salt; [9] Nickel(II) isooctanoate; [10] Nickel isooctanoate; [11] Nickel bis(isononanoate); [12] Nickel(II) neononanoate; [13] Nickel(II) isodecanoate; [14] Nickel(II) neodecanoate; [15] Neodecanoic acid, nickel salt; [16] Nickel(II) neoundecanoate; [17] Bis(D-gluconato-O1,O2)nickel; [18] Nickel 3,5-bis(tert-butyl)-4-hydroxybenzoate (1:2); [19] Nickel(II) palmitate; [20] (2-Ethylhexanoato-O)(Isononanoato-O)nickel; [21] (Isononanoato-O)(Isooctanoato-O)nickel; [22] (Isooctanoato-O)(neodecanoato-O)nickel; [23] (2-Ethylhexanoato-O)(Isodecanoato-O)nickel; [24] (2-Ethylhexanoato-O)(Neodecanoato-O)nickel; [25] (Isodecanoato-O)(isooctanoato-O)nickel; [26] (Isodecanoato-O)(isononanoato-O)nickel; [27] (Isononanoato-O)(Neodecanoato-O)nickel; [28] fatty acids, C6-19-branched, nickel salts; [29] fatty acids, C8-18 and C18-unsaturated, nickel salts; [30] 2,7-Naphthalenedisulfonic acid, nickel(II) salt; [31]

Regulatory information

Regulation

(EU) 2019/831

See every entry this act set

Key data

CAS
16083-14-0 [1] 3349-08-4 [2] 39819-65-3 [3] 18721-51-2 [4] 18283-82-4 [5] 22605-92-1 [6] 4454-16-4 [7] 7580-31-6 [8] 93983-68-7 [9] 29317-63-3 [10] 27637-46-3 [11] 84852-37-9 [12] 93920-10-6 [13] 85508-43-6 [14] 85508-44-7 [15] 51818-56-5 [16] 93920-
EC
240-235-8 [1] 222-102-6 [2] 254-642-3 [3] 242-533-3 [4] 242-161-1 [5] 245-119-0 [6] 224-699-9 [7] 231-480-1 [8] 301-323-2 [9] 249-555-2 [10] 248-585-3 [11] 284-349-6 [12] 300-094-6 [13] 287-468-1 [14] 287-469-7 [15] 257-447-1 [16] 300-093-0 [17] 276-
Annex
Entry number
1460

Direct matches are limited for this record, so nearby entries from Annex II are shown as well.

Annex II 1463
Nearby record in the same annex

Dialuminium nickel tetraoxide [1]; Nickel titanium trioxide [2]; Nickel titanium oxide [3]; Nickel …

CAS: 12004-35-2 [1] / 12035-39-1 [2] / 12653-76-8 [3] / 52502-12-2 [4] / 68016-03-5 [5] / 70692-93-2 [6] / 14177-55-0 [7] / 14177-51-6 [8] / 68515-84-4 [9] / 12031-65-1 [10] / 12673-58-4 [11]
EC: 234-454-8 [1] / 234-825-4 [2] / 235-752-0 [3] / 257-970-5 [4] / 268-169-5 [5] / 274-755-1 [6] / 238-034-5 [7] / 238-032-4 [8] / 271-112-7 [9] / - [10] / - [11]
Annex II 1455
Nearby record in the same annex

Nickel selenide

CAS: 1314-05-2
EC: 215-216-2

What Annex II means for Nickel(II) trifluoroacetate; [1] Nickel(II) propionate; [2] Nickel bis(benzenesulfonate); [3] Nickel(II) hydrogen citrate; [4] Citric acid, ammonium nickel salt; [5] Citric acid, nickel salt; [6] Nickel bis(2-ethylhexanoate); [7] 2-Ethylhexanoic acid, Nickel salt; [8] Dimethylhexanoic acid nickel salt; [9] Nickel(II) isooctanoate; [10] Nickel isooctanoate; [11] Nickel bis(isononanoate); [12] Nickel(II) neononanoate; [13] Nickel(II) isodecanoate; [14] Nickel(II) neodecanoate; [15] Neodecanoic acid, nickel salt; [16] Nickel(II) neoundecanoate; [17] Bis(D-gluconato-O1,O2)nickel; [18] Nickel 3,5-bis(tert-butyl)-4-hydroxybenzoate (1:2); [19] Nickel(II) palmitate; [20] (2-Ethylhexanoato-O)(Isononanoato-O)nickel; [21] (Isononanoato-O)(Isooctanoato-O)nickel; [22] (Isooctanoato-O)(neodecanoato-O)nickel; [23] (2-Ethylhexanoato-O)(Isodecanoato-O)nickel; [24] (2-Ethylhexanoato-O)(Neodecanoato-O)nickel; [25] (Isodecanoato-O)(isooctanoato-O)nickel; [26] (Isodecanoato-O)(isononanoato-O)nickel; [27] (Isononanoato-O)(Neodecanoato-O)nickel; [28] fatty acids, C6-19-branched, nickel salts; [29] fatty acids, C8-18 and C18-unsaturated, nickel salts; [30] 2,7-Naphthalenedisulfonic acid, nickel(II) salt; [31]

Nickel(II) trifluoroacetate; [1] Nickel(II) propionate; [2] Nickel bis(benzenesulfonate); [3] Nickel(II) hydrogen citrate; [4] Citric acid, ammonium nickel salt; [5] Citric acid, nickel salt; [6] Nickel bis(2-ethylhexanoate); [7] 2-Ethylhexanoic acid, Nickel salt; [8] Dimethylhexanoic acid nickel salt; [9] Nickel(II) isooctanoate; [10] Nickel isooctanoate; [11] Nickel bis(isononanoate); [12] Nickel(II) neononanoate; [13] Nickel(II) isodecanoate; [14] Nickel(II) neodecanoate; [15] Neodecanoic acid, nickel salt; [16] Nickel(II) neoundecanoate; [17] Bis(D-gluconato-O1,O2)nickel; [18] Nickel 3,5-bis(tert-butyl)-4-hydroxybenzoate (1:2); [19] Nickel(II) palmitate; [20] (2-Ethylhexanoato-O)(Isononanoato-O)nickel; [21] (Isononanoato-O)(Isooctanoato-O)nickel; [22] (Isooctanoato-O)(neodecanoato-O)nickel; [23] (2-Ethylhexanoato-O)(Isodecanoato-O)nickel; [24] (2-Ethylhexanoato-O)(Neodecanoato-O)nickel; [25] (Isodecanoato-O)(isooctanoato-O)nickel; [26] (Isodecanoato-O)(isononanoato-O)nickel; [27] (Isononanoato-O)(Neodecanoato-O)nickel; [28] fatty acids, C6-19-branched, nickel salts; [29] fatty acids, C8-18 and C18-unsaturated, nickel salts; [30] 2,7-Naphthalenedisulfonic acid, nickel(II) salt; [31] is listed as a prohibited substance under Annex II of EU Cosmetics Regulation 1223/2009 and must not be intentionally added. Article 17 separately addresses unintended small quantities that are technically unavoidable under good manufacturing practice and compatible with the Article 3 safety requirement.

Formulators must screen their ingredients and raw materials to ensure none contain this substance. Suppliers should provide documentation confirming absence when requested.

The page also surfaces 12 related annex records with overlapping identifiers, annex logic or naming patterns.

Compliance checklist

  • Verify this substance is absent from all raw materials and finished formulations.
  • Request absence confirmation or CoA from raw material suppliers.
  • Document the screening result in the Product Information File (PIF).

Frequently asked questions

Yes. Nickel(II) trifluoroacetate; [1] Nickel(II) propionate; [2] Nickel bis(benzenesulfonate); [3] Nickel(II) hydrogen citrate; [4] Citric acid, ammonium nickel salt; [5] Citric acid, nickel salt; [6] Nickel bis(2-ethylhexanoate); [7] 2-Ethylhexanoic acid, Nickel salt; [8] Dimethylhexanoic acid nickel salt; [9] Nickel(II) isooctanoate; [10] Nickel isooctanoate; [11] Nickel bis(isononanoate); [12] Nickel(II) neononanoate; [13] Nickel(II) isodecanoate; [14] Nickel(II) neodecanoate; [15] Neodecanoic acid, nickel salt; [16] Nickel(II) neoundecanoate; [17] Bis(D-gluconato-O1,O2)nickel; [18] Nickel 3,5-bis(tert-butyl)-4-hydroxybenzoate (1:2); [19] Nickel(II) palmitate; [20] (2-Ethylhexanoato-O)(Isononanoato-O)nickel; [21] (Isononanoato-O)(Isooctanoato-O)nickel; [22] (Isooctanoato-O)(neodecanoato-O)nickel; [23] (2-Ethylhexanoato-O)(Isodecanoato-O)nickel; [24] (2-Ethylhexanoato-O)(Neodecanoato-O)nickel; [25] (Isodecanoato-O)(isooctanoato-O)nickel; [26] (Isodecanoato-O)(isononanoato-O)nickel; [27] (Isononanoato-O)(Neodecanoato-O)nickel; [28] fatty acids, C6-19-branched, nickel salts; [29] fatty acids, C8-18 and C18-unsaturated, nickel salts; [30] 2,7-Naphthalenedisulfonic acid, nickel(II) salt; [31] is listed in Annex II of EU Cosmetics Regulation 1223/2009 and is prohibited as an intentionally added cosmetic ingredient. Article 17 provides a narrow exception for unintended small quantities that are technically unavoidable under good manufacturing practice, provided the product remains safe under Article 3.

CAS 16083-14-0 [1] 3349-08-4 [2] 39819-65-3 [3] 18721-51-2 [4] 18283-82-4 [5] 22605-92-1 [6] 4454-16-4 [7] 7580-31-6 [8] 93983-68-7 [9] 29317-63-3 [10] 27637-46-3 [11] 84852-37-9 [12] 93920-10-6 [13] 85508-43-6 [14] 85508-44-7 [15] 51818-56-5 [16] 93920- is the unique numerical identifier assigned to Nickel(II) trifluoroacetate; [1] Nickel(II) propionate; [2] Nickel bis(benzenesulfonate); [3] Nickel(II) hydrogen citrate; [4] Citric acid, ammonium nickel salt; [5] Citric acid, nickel salt; [6] Nickel bis(2-ethylhexanoate); [7] 2-Ethylhexanoic acid, Nickel salt; [8] Dimethylhexanoic acid nickel salt; [9] Nickel(II) isooctanoate; [10] Nickel isooctanoate; [11] Nickel bis(isononanoate); [12] Nickel(II) neononanoate; [13] Nickel(II) isodecanoate; [14] Nickel(II) neodecanoate; [15] Neodecanoic acid, nickel salt; [16] Nickel(II) neoundecanoate; [17] Bis(D-gluconato-O1,O2)nickel; [18] Nickel 3,5-bis(tert-butyl)-4-hydroxybenzoate (1:2); [19] Nickel(II) palmitate; [20] (2-Ethylhexanoato-O)(Isononanoato-O)nickel; [21] (Isononanoato-O)(Isooctanoato-O)nickel; [22] (Isooctanoato-O)(neodecanoato-O)nickel; [23] (2-Ethylhexanoato-O)(Isodecanoato-O)nickel; [24] (2-Ethylhexanoato-O)(Neodecanoato-O)nickel; [25] (Isodecanoato-O)(isooctanoato-O)nickel; [26] (Isodecanoato-O)(isononanoato-O)nickel; [27] (Isononanoato-O)(Neodecanoato-O)nickel; [28] fatty acids, C6-19-branched, nickel salts; [29] fatty acids, C8-18 and C18-unsaturated, nickel salts; [30] 2,7-Naphthalenedisulfonic acid, nickel(II) salt; [31] by the Chemical Abstracts Service. In cosmetic compliance work, the CAS number is used to cross-reference the substance across regulatory databases, raw material specifications and safety assessment reports. Multiple EU annex entries may share the same CAS number if the same substance appears under different conditions or in different annexes.

Use the INCI Checker tool on this site to paste your full ingredient list (INCI) and scan it against all Annex II–VI entries. The tool highlights any ingredients that match restricted, prohibited or allergen-flagged records. This is useful for rapid compliance screening of finished product formulas or raw material declarations.

Source note for Annex II record Nickel(II) trifluoroacetate; [1] Nickel(II) propionate; [2] Nickel bis(benzenesulfonate); [3] Nickel(II) hydrogen citrate; [4] Citric acid, ammonium nickel salt; [5] Citric acid, nickel salt; [6] Nickel bis(2-ethylhexanoate); [7] 2-Ethylhexanoic acid, Nickel salt; [8] Dimethylhexanoic acid nickel salt; [9] Nickel(II) isooctanoate; [10] Nickel isooctanoate; [11] Nickel bis(isononanoate); [12] Nickel(II) neononanoate; [13] Nickel(II) isodecanoate; [14] Nickel(II) neodecanoate; [15] Neodecanoic acid, nickel salt; [16] Nickel(II) neoundecanoate; [17] Bis(D-gluconato-O1,O2)nickel; [18] Nickel 3,5-bis(tert-butyl)-4-hydroxybenzoate (1:2); [19] Nickel(II) palmitate; [20] (2-Ethylhexanoato-O)(Isononanoato-O)nickel; [21] (Isononanoato-O)(Isooctanoato-O)nickel; [22] (Isooctanoato-O)(neodecanoato-O)nickel; [23] (2-Ethylhexanoato-O)(Isodecanoato-O)nickel; [24] (2-Ethylhexanoato-O)(Neodecanoato-O)nickel; [25] (Isodecanoato-O)(isooctanoato-O)nickel; [26] (Isodecanoato-O)(isononanoato-O)nickel; [27] (Isononanoato-O)(Neodecanoato-O)nickel; [28] fatty acids, C6-19-branched, nickel salts; [29] fatty acids, C8-18 and C18-unsaturated, nickel salts; [30] 2,7-Naphthalenedisulfonic acid, nickel(II) salt; [31]

This page summarizes one Annex II record for Nickel(II) trifluoroacetate; [1] Nickel(II) propionate; [2] Nickel bis(benzenesulfonate); [3] Nickel(II) hydrogen citrate; [4] Citric acid, ammonium nickel salt; [5] Citric acid, nickel salt; [6] Nickel bis(2-ethylhexanoate); [7] 2-Ethylhexanoic acid, Nickel salt; [8] Dimethylhexanoic acid nickel salt; [9] Nickel(II) isooctanoate; [10] Nickel isooctanoate; [11] Nickel bis(isononanoate); [12] Nickel(II) neononanoate; [13] Nickel(II) isodecanoate; [14] Nickel(II) neodecanoate; [15] Neodecanoic acid, nickel salt; [16] Nickel(II) neoundecanoate; [17] Bis(D-gluconato-O1,O2)nickel; [18] Nickel 3,5-bis(tert-butyl)-4-hydroxybenzoate (1:2); [19] Nickel(II) palmitate; [20] (2-Ethylhexanoato-O)(Isononanoato-O)nickel; [21] (Isononanoato-O)(Isooctanoato-O)nickel; [22] (Isooctanoato-O)(neodecanoato-O)nickel; [23] (2-Ethylhexanoato-O)(Isodecanoato-O)nickel; [24] (2-Ethylhexanoato-O)(Neodecanoato-O)nickel; [25] (Isodecanoato-O)(isooctanoato-O)nickel; [26] (Isodecanoato-O)(isononanoato-O)nickel; [27] (Isononanoato-O)(Neodecanoato-O)nickel; [28] fatty acids, C6-19-branched, nickel salts; [29] fatty acids, C8-18 and C18-unsaturated, nickel salts; [30] 2,7-Naphthalenedisulfonic acid, nickel(II) salt; [31] from public European Commission cosmetic materials and adds linked inventory or identifier matches when available.

Use this record page to review Annex II conditions for Nickel(II) trifluoroacetate; [1] Nickel(II) propionate; [2] Nickel bis(benzenesulfonate); [3] Nickel(II) hydrogen citrate; [4] Citric acid, ammonium nickel salt; [5] Citric acid, nickel salt; [6] Nickel bis(2-ethylhexanoate); [7] 2-Ethylhexanoic acid, Nickel salt; [8] Dimethylhexanoic acid nickel salt; [9] Nickel(II) isooctanoate; [10] Nickel isooctanoate; [11] Nickel bis(isononanoate); [12] Nickel(II) neononanoate; [13] Nickel(II) isodecanoate; [14] Nickel(II) neodecanoate; [15] Neodecanoic acid, nickel salt; [16] Nickel(II) neoundecanoate; [17] Bis(D-gluconato-O1,O2)nickel; [18] Nickel 3,5-bis(tert-butyl)-4-hydroxybenzoate (1:2); [19] Nickel(II) palmitate; [20] (2-Ethylhexanoato-O)(Isononanoato-O)nickel; [21] (Isononanoato-O)(Isooctanoato-O)nickel; [22] (Isooctanoato-O)(neodecanoato-O)nickel; [23] (2-Ethylhexanoato-O)(Isodecanoato-O)nickel; [24] (2-Ethylhexanoato-O)(Neodecanoato-O)nickel; [25] (Isodecanoato-O)(isooctanoato-O)nickel; [26] (Isodecanoato-O)(isononanoato-O)nickel; [27] (Isononanoato-O)(Neodecanoato-O)nickel; [28] fatty acids, C6-19-branched, nickel salts; [29] fatty acids, C8-18 and C18-unsaturated, nickel salts; [30] 2,7-Naphthalenedisulfonic acid, nickel(II) salt; [31], but confirm any final regulatory decision against the current official annex wording and source files.

Tools & next steps

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Paste a full INCI list to detect Nickel(II) trifluoroacetate; [1] Nickel(II) propionate; [2] Nickel bis(benzenesulfonate); [3] Nickel(II) hydrogen citrate; [4] Citric acid, ammonium nickel salt; [5] Citric acid, nickel salt; [6] Nickel bis(2-ethylhexanoate); [7] 2-Ethylhexanoic acid, Nickel salt; [8] Dimethylhexanoic acid nickel salt; [9] Nickel(II) isooctanoate; [10] Nickel isooctanoate; [11] Nickel bis(isononanoate); [12] Nickel(II) neononanoate; [13] Nickel(II) isodecanoate; [14] Nickel(II) neodecanoate; [15] Neodecanoic acid, nickel salt; [16] Nickel(II) neoundecanoate; [17] Bis(D-gluconato-O1,O2)nickel; [18] Nickel 3,5-bis(tert-butyl)-4-hydroxybenzoate (1:2); [19] Nickel(II) palmitate; [20] (2-Ethylhexanoato-O)(Isononanoato-O)nickel; [21] (Isononanoato-O)(Isooctanoato-O)nickel; [22] (Isooctanoato-O)(neodecanoato-O)nickel; [23] (2-Ethylhexanoato-O)(Isodecanoato-O)nickel; [24] (2-Ethylhexanoato-O)(Neodecanoato-O)nickel; [25] (Isodecanoato-O)(isooctanoato-O)nickel; [26] (Isodecanoato-O)(isononanoato-O)nickel; [27] (Isononanoato-O)(Neodecanoato-O)nickel; [28] fatty acids, C6-19-branched, nickel salts; [29] fatty acids, C8-18 and C18-unsaturated, nickel salts; [30] 2,7-Naphthalenedisulfonic acid, nickel(II) salt; [31] and other flagged EU annex records in one pass.

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Compare Nickel(II) trifluoroacetate; [1] Nickel(II) propionate; [2] Nickel bis(benzenesulfonate); [3] Nickel(II) hydrogen citrate; [4] Citric acid, ammonium nickel salt; [5] Citric acid, nickel salt; [6] Nickel bis(2-ethylhexanoate); [7] 2-Ethylhexanoic acid, Nickel salt; [8] Dimethylhexanoic acid nickel salt; [9] Nickel(II) isooctanoate; [10] Nickel isooctanoate; [11] Nickel bis(isononanoate); [12] Nickel(II) neononanoate; [13] Nickel(II) isodecanoate; [14] Nickel(II) neodecanoate; [15] Neodecanoic acid, nickel salt; [16] Nickel(II) neoundecanoate; [17] Bis(D-gluconato-O1,O2)nickel; [18] Nickel 3,5-bis(tert-butyl)-4-hydroxybenzoate (1:2); [19] Nickel(II) palmitate; [20] (2-Ethylhexanoato-O)(Isononanoato-O)nickel; [21] (Isononanoato-O)(Isooctanoato-O)nickel; [22] (Isooctanoato-O)(neodecanoato-O)nickel; [23] (2-Ethylhexanoato-O)(Isodecanoato-O)nickel; [24] (2-Ethylhexanoato-O)(Neodecanoato-O)nickel; [25] (Isodecanoato-O)(isooctanoato-O)nickel; [26] (Isodecanoato-O)(isononanoato-O)nickel; [27] (Isononanoato-O)(Neodecanoato-O)nickel; [28] fatty acids, C6-19-branched, nickel salts; [29] fatty acids, C8-18 and C18-unsaturated, nickel salts; [30] 2,7-Naphthalenedisulfonic acid, nickel(II) salt; [31] side by side with another annex record to review differences in restrictions, concentrations and annex placement.

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