5,12-Dihydroquino[2,3-b]acridine-7,14-dione (Pigment Violet 19; CI 73900) when used as a substance in hair dye products
5,12-Dihydroquino[2,3-b]acridine-7,14-dione (Pigment Violet 19; CI 73900) when used as a substance in hair dye products is listed in Annex II as a prohibited substance for cosmetic products placed on the EU market.
Chemical identity and properties
Quinacridone
Quinacridone is an organonitrogen heterocyclic compound and an organic heterotetracyclic compound. — ChEBI
- IUPAC name
- 5,12-dihydroquinolino[2,3-b]acridine-7,14-dione
- Molecular formula
- C20H12N2O2
- Molecular weight
- 312.3 g/mol
- Exact mass
- 312.089877630 Da
- XLogP3
- 4.0
- Topological polar surface area
- 58.2 Ų
- Hydrogen-bond donors
- 2
- Hydrogen-bond acceptors
- 4
- Covalent units
- 1
- Defined stereocentres
- 0
Also known as
16 more reported names
External database identifiers
Evidence from additional scientific databases
EMBL-EBI ChEBI
Quinacridone
- Formula
- C20H12N2O2
- Average mass
- 312.328 g/mol
- Monoisotopic mass
- 312.08988 Da
- Formal charge
- 0
- organonitrogen heterocyclic compound — is a (CHEBI:38101)
- organic heterotetracyclic compound — is a (CHEBI:38163)
- organonitrogen heterocyclic compound — is a (CHEBI:38101)
- organic heterotetracyclic compound — is a (CHEBI:38163)
Additional curated names
Cross-references from this source
- CAS: 1047-16-1 — ChemIDplus
- MANUAL_X_REF: 13369 — ChemSpider
- MANUAL_X_REF: HMDB0034058 — HMDB
Mapped by: Exact CAS cross-reference in the ChEBI compound record. Retrieved: 2026-08-31. Open source record
NIH PubChem PUG-View
Attributed physical-property, hazard, environmental and use annotations.
- Color/Form: Red to violet solid with blueish or yellowish tint depending upon crystalline form. Source: Hazardous Substances Data Bank (HSDB)
- Color/Form: particle characteristics: thin plates Source: Hazardous Substances Data Bank (HSDB)
- Density: 1.5 Source: Hazardous Substances Data Bank (HSDB)
- LogP: 1.9 (estimated) Source: Hazardous Substances Data Bank (HSDB)
- Melting Point: 390 °C Source: Human Metabolome Database (HMDB)
- Physical Description: Liquid; Other Solid; Dry Powder; Other Solid; CBI Source: EPA Chemical Data Reporting (CDR)
- Physical Description: Red to violet solid; Bluish or yellowish tint depending of form; [HSDB] Red odorless powder; [MSDSonline] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Physical Description: Solid Source: Human Metabolome Database (HMDB)
- Refractive Index: Refractive index: quinacridine red (gamma), n(Na) Av. 2.04; quinacridine red (beta), Av. 2.02 Source: Hazardous Substances Data Bank (HSDB)
- Solubility: Insoluble in water Source: Hazardous Substances Data Bank (HSDB)
- Solubility: Insoluble in organic solvents and dispersion media. Source: Hazardous Substances Data Bank (HSDB)
- Note: This chemical does not meet GHS hazard criteria for 99.6% (760 of 763) of all reports. Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: Not Classified; Reported as not meeting GHS hazard criteria by 760 of 763 companies (only 0.4% companies provided GHS information). For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 763 reports by companies from 4 notifications to the ECHA C&L Inventory.; Reported as not meeting GHS hazard criteria per 760 of 763 reports by companies.; There are 2 notifications provided by 3 of 763 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- Environmental Bioconcentration: Cinquasia red should not bioconcentrate, since it is insoluble, and therefore, will not be taken up into the body. Source: Hazardous Substances Data Bank (HSDB)
- Environmental Fate: Much of cinquasia red will be bound up in the components of landfills, junkyards, and general dump sites. Source: Hazardous Substances Data Bank (HSDB)
- Environmental Fate: Terrestrial: The insolubility of cinquasia red will cause it to collect in soils and sediments. Source: Hazardous Substances Data Bank (HSDB)
- Environmental Fate: Aquatic: Due to its insolubility, cinquasia red may reside in the water column for a substantial period, long enough to become part of deep sea sediments. Source: Hazardous Substances Data Bank (HSDB)
- Consumer Uses: Pigment Source: EPA Chemical Data Reporting (CDR)
- Industry Uses: Pigment Source: EPA Chemical Data Reporting (CDR)
- Sources/Uses: Used as pigment (paints, printing inks, plastics, rubber, alkyd resin enamels, textile emulsion inks, textiles, nitrocellulose, vinyl, and acrylic lacquers) and sensitizing dye in color photo electrophoresis; Used to tone and make other pigments; [HSDB] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Industrial Processes with risk of exposure: Painting (Pigments, Binders, and Biocides) [Category: Paint]; Textiles (Printing, Dyeing, or Finishing) [Category: Industry] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Uses: PAINTS, PRINTING INKS, PLASTICS, RUBBER Source: Hazardous Substances Data Bank (HSDB)
- Uses: Cinquasia red is used a sensitizing dye in color photoelectrophoresis. Source: Hazardous Substances Data Bank (HSDB)
- Uses: Pigment in textiles Source: Hazardous Substances Data Bank (HSDB)
- Uses: As colorants for plastics, quinacridone pigments may be used in all resins except nylon-66 and polystyrene./Quinacridone Pigments/ Source: Hazardous Substances Data Bank (HSDB)
- Uses: For more Uses (Complete) data for CINQUASIA RED (9 total), please visit the HSDB record page. Source: Hazardous Substances Data Bank (HSDB)
- Uses: Plastics -> Typical concentration range in plastic materials -> 2% Source: NORMAN Suspect List Exchange
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| EMBL-EBI ChEBI | Exact match | 2026-08-31 |
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Record details
Chemical name
5,12-Dihydroquino[2,3-b]acridine-7,14-dione (Pigment Violet 19; CI 73900) when used as a substance in hair dye products
Regulatory information
Identified ingredients
Key data
Inventory links for 5,12-Dihydroquino[2,3-b]acridine-7,14-dione (Pigment Violet 19; CI 73900) when used as a substance in hair dye products
Related records for 5,12-Dihydroquino[2,3-b]acridine-7,14-dione (Pigment Violet 19; CI 73900) when used as a substance in hair dye products
Direct matches are limited for this record, so nearby entries from Annex II are shown as well.
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What Annex II means for 5,12-Dihydroquino[2,3-b]acridine-7,14-dione (Pigment Violet 19; CI 73900) when used as a substance in hair dye products
5,12-Dihydroquino[2,3-b]acridine-7,14-dione (Pigment Violet 19; CI 73900) when used as a substance in hair dye products is listed as a prohibited substance under Annex II of EU Cosmetics Regulation 1223/2009 and must not be intentionally added. Article 17 separately addresses unintended small quantities that are technically unavoidable under good manufacturing practice and compatible with the Article 3 safety requirement.
Formulators must screen their ingredients and raw materials to ensure none contain this substance. Suppliers should provide documentation confirming absence when requested.
This record is linked to 2 CosIng inventory ingredients for name and identifier cross-reference. The page also surfaces 12 related annex records with overlapping identifiers, annex logic or naming patterns.
Compliance checklist
- Verify this substance is absent from all raw materials and finished formulations.
- Request absence confirmation or CoA from raw material suppliers.
- Document the screening result in the Product Information File (PIF).
Frequently asked questions
Source note for Annex II record 5,12-Dihydroquino[2,3-b]acridine-7,14-dione (Pigment Violet 19; CI 73900) when used as a substance in hair dye products
This page summarizes one Annex II record for 5,12-Dihydroquino[2,3-b]acridine-7,14-dione (Pigment Violet 19; CI 73900) when used as a substance in hair dye products from public European Commission cosmetic materials and adds linked inventory or identifier matches when available.
Use this record page to review Annex II conditions for 5,12-Dihydroquino[2,3-b]acridine-7,14-dione (Pigment Violet 19; CI 73900) when used as a substance in hair dye products, but confirm any final regulatory decision against the current official annex wording and source files.
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