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Annex II Entry 1239 21/10/2010

HC Red No 8 and its salts

HC Red No 8 and its salts is listed in Annex II as a prohibited substance for cosmetic products placed on the EU market.

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Prohibited substance— Annex II, EU Regulation 1223/2009
Entry: 1239

Chemical identity and properties

PubChem 2D chemical structure for CAS 13556-29-1
CAS 13556-29-1PubChem CID 10802699

1-((3-Aminopropyl)amino)anthracene-9,10-dione

IUPAC name
1-(3-aminopropylamino)anthracene-9,10-dione
Molecular formula
C17H16N2O2
Molecular weight
280.32 g/mol
Exact mass
280.121177757 Da
XLogP3
3.3
Topological polar surface area
72.2 Ų
Hydrogen-bond donors
2
Hydrogen-bond acceptors
4
Covalent units
1
Defined stereocentres
0

Also known as

1-[(3-AMINOPROPYL)AMINO]ANTHRACENE-9,10-DIONERefChem:222074HC RED NO. 81-[(3-Aminopropyl)amino]anthraquinone1-((3-aminopropyl)amino)-9,10-anthraquinone
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 97404-14-3
CAS 97404-14-3PubChem CID 14320098

1-((3-Aminopropyl)amino)anthraquinone, monohydrochloride

IUPAC name
1-(3-aminopropylamino)anthracene-9,10-dione;hydrochloride
Molecular formula
C17H17ClN2O2
Molecular weight
316.8 g/mol
Exact mass
316.0978555 Da
Topological polar surface area
72.2 Ų
Hydrogen-bond donors
3
Hydrogen-bond acceptors
4
Covalent units
2
Defined stereocentres
0

Also known as

EINECS 306-778-01-[(3-Aminopropyl)amino]anthraquinone, monohydrochlorideRefChem:73842306-778-01-((3-Aminopropyl)amino)anthracene-9,10-dione hydrochloride9,10-Anthracenedione, 1-[(3-aminopropyl)amino]-, hydrochloride (1:1)HCREDNO.8HYDROCHLORIDEMXSLXRJZWUIWCV-UHFFFAOYSA-N
5 more reported names
BS-500971-<(3-aminopropyl)amino>anthraquinone*HCl1-((3-Aminopropyl)amino)anthracene-9,10-dionehydrochloride1-[(3-aminopropyl)amino]anthraquinone, monohydrochloride1-[(3-Aminopropyl)amino]anthracene-9,10-dione--hydrogen chloride (1/1)
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Record details

Chemical name

HC Red No 8 and its salts

Regulatory information

Regulation

(EC) 2009/1223

See every entry this act set

SCCS opinions

Identified ingredients

Key data

CAS
13556-29-1 / 97404-14-3
EC
- / 306-778-0
Annex
II
Entry number
1239

Inventory links for HC Red No 8 and its salts

Inventory Restriction reference
Ref 34210

HC RED NO. 8

CAS: 13556-29-1 / 97404-14-3 / 41959-35-7
EC: - / 306-778-0 / -

Direct matches are limited for this record, so nearby entries from Annex II are shown as well.

Annex II 1238
Nearby record in the same annex

HC Green No 1

CAS: 52136-25-1
EC: 257-687-7

What Annex II means for HC Red No 8 and its salts

HC Red No 8 and its salts is listed as a prohibited substance under Annex II of EU Cosmetics Regulation 1223/2009 and must not be intentionally added. Article 17 separately addresses unintended small quantities that are technically unavoidable under good manufacturing practice and compatible with the Article 3 safety requirement.

Formulators must screen their ingredients and raw materials to ensure none contain this substance. Suppliers should provide documentation confirming absence when requested.

This record is linked to 1 CosIng inventory ingredient for name and identifier cross-reference. The page also surfaces 12 related annex records with overlapping identifiers, annex logic or naming patterns.

Compliance checklist

  • Verify this substance is absent from all raw materials and finished formulations.
  • Request absence confirmation or CoA from raw material suppliers.
  • Document the screening result in the Product Information File (PIF).

Frequently asked questions

Yes. HC Red No 8 and its salts is listed in Annex II of EU Cosmetics Regulation 1223/2009 and is prohibited as an intentionally added cosmetic ingredient. Article 17 provides a narrow exception for unintended small quantities that are technically unavoidable under good manufacturing practice, provided the product remains safe under Article 3.

CAS 13556-29-1 / 97404-14-3 is the unique numerical identifier assigned to HC Red No 8 and its salts by the Chemical Abstracts Service. In cosmetic compliance work, the CAS number is used to cross-reference the substance across regulatory databases, raw material specifications and safety assessment reports. Multiple EU annex entries may share the same CAS number if the same substance appears under different conditions or in different annexes.

Use the INCI Checker tool on this site to paste your full ingredient list (INCI) and scan it against all Annex II–VI entries. The tool highlights any ingredients that match restricted, prohibited or allergen-flagged records. This is useful for rapid compliance screening of finished product formulas or raw material declarations.
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Source note for Annex II record HC Red No 8 and its salts

This page summarizes one Annex II record for HC Red No 8 and its salts from public European Commission cosmetic materials and adds linked inventory or identifier matches when available.

Use this record page to review Annex II conditions for HC Red No 8 and its salts, but confirm any final regulatory decision against the current official annex wording and source files.

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