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Annex II Entry 1073 CMR15/10/2010

Chlordane, pur

Chlordane, pur is listed in Annex II as a prohibited substance for cosmetic products placed on the EU market.

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Prohibited substance— Annex II, EU Regulation 1223/2009
Entry: 1073
CMR

Chemical identity and properties

PubChem 2D chemical structure for CAS 57-74-9
CAS 57-74-9PubChem CID 11954021

Chlordane

Chlordane is a manufactured chemical that was used as a pesticide in the United States from 1948 to 1988. Technical chlordane is not a single chemical, but is actually a mixture of pure chlordane mixed with many related chemicals. It doesn't occur naturally in the environment. It is a thick liquid whose color ranges from colorless to amber. Chlordane has a mild, irritating smell. Some of its trade names are Octachlor and Velsicol 1068. Until 1983, chlordane was used as a pesticide on crops like corn and citrus and on home lawns and gardens. Because of concern about damage to the environment and harm to human health, the Environmental Protection Agency (EPA) banned all uses of chlordane in 1983 except to control termites. In 1988, EPA banned all uses. — Agency for Toxic Substances and Disease Registry (ATSDR)

IUPAC name
(1R,7S)-1,3,4,7,8,9,10,10-octachlorotricyclo[5.2.1.02,6]dec-8-ene
Molecular formula
C10H6Cl8
Molecular weight
409.8 g/mol
Exact mass
409.791872 Da
XLogP3
4.9
Topological polar surface area
0.0 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
0
Covalent units
1
Defined stereocentres
2

Also known as

ChloordaanClordanClordanoDowchlorOktaterrSynklorTopiclorAspon-chlordane
16 more reported names
Cortilan-neuKilex lindaneDichlorochlordeneTermi-dedOcta-KlorTopichlor 20Chlordane [ISO]Clordan [Italian]Topiclor 20Intox 8Chloordaan [Dutch]Tat Chlor 4Velsicol 1068ChlorindanCaswell No. 174Shell sd-5532
Open full PubChem recordPubChem annotations3D structure image

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Record details

Chemical name

Chlordane, pur

Chemical / IUPAC name

1,2,4,5,6,7,8,8-octachloro-3a,4,7,7a-tetrahydro-4,7-methanoindan

Regulatory information

Regulation

(EC) 2009/1223

See every entry this act set

SCCS opinions

CMR

CategoryCarcinogenicMutagenicReprotoxic
Cat. 2✓——

Key data

CAS
57-74-9
EC
200-349-0
Annex
II
Entry number
1073

Direct matches are limited for this record, so nearby entries from Annex II are shown as well.

Annex II 1072
Nearby record in the same annex

Fenthion (ISO)

CAS: 55-38-9
EC: 200-231-9
Annex II 1075
Nearby record in the same annex

Fenarimol (ISO)

CAS: 60168-88-9
EC: 262-095-7
Annex II 1076
Nearby record in the same annex

Acetamide

CAS: 60-35-5
EC: 200-473-5
Annex II 1068
Nearby record in the same annex

DNOC (ISO)

CAS: 534-52-1
EC: 208-601-1
Annex II 1078
Nearby record in the same annex

Dieldrin (ISO)

CAS: 60-57-1
EC: 200-484-5

What Annex II means for Chlordane, pur

Chlordane, pur is listed as a prohibited substance under Annex II of EU Cosmetics Regulation 1223/2009 and must not be intentionally added. Article 17 separately addresses unintended small quantities that are technically unavoidable under good manufacturing practice and compatible with the Article 3 safety requirement.

Formulators must screen their ingredients and raw materials to ensure none contain this substance. Suppliers should provide documentation confirming absence when requested.

The page also surfaces 12 related annex records with overlapping identifiers, annex logic or naming patterns.

Compliance checklist

  • Verify this substance is absent from all raw materials and finished formulations.
  • Request absence confirmation or CoA from raw material suppliers.
  • Document the screening result in the Product Information File (PIF).
  • This substance has CMR classification. Review the CMR table above and verify current Annex II/III status before use.

Frequently asked questions

Yes. Chlordane, pur is listed in Annex II of EU Cosmetics Regulation 1223/2009 and is prohibited as an intentionally added cosmetic ingredient. Article 17 provides a narrow exception for unintended small quantities that are technically unavoidable under good manufacturing practice, provided the product remains safe under Article 3.

CAS 57-74-9 is the unique numerical identifier assigned to Chlordane, pur by the Chemical Abstracts Service. In cosmetic compliance work, the CAS number is used to cross-reference the substance across regulatory databases, raw material specifications and safety assessment reports. Multiple EU annex entries may share the same CAS number if the same substance appears under different conditions or in different annexes.

Chlordane, pur has a CMR (carcinogenic, mutagenic or reprotoxic) classification under EU CLP Regulation. Under Article 15 of EU Cosmetics Regulation 1223/2009, CMR substances of category 1A or 1B are prohibited in cosmetics unless specifically permitted. Category 2 CMR substances may be used only if assessed safe by the SCCS. Always verify current annex status and any applicable derogations before use.

Use the INCI Checker tool on this site to paste your full ingredient list (INCI) and scan it against all Annex II–VI entries. The tool highlights any ingredients that match restricted, prohibited or allergen-flagged records. This is useful for rapid compliance screening of finished product formulas or raw material declarations.
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Source note for Annex II record Chlordane, pur

This page summarizes one Annex II record for Chlordane, pur from public European Commission cosmetic materials and adds linked inventory or identifier matches when available.

Use this record page to review Annex II conditions for Chlordane, pur, but confirm any final regulatory decision against the current official annex wording and source files.

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