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Permitted list with conditionsBinding ruleUSOriginal is EnglishOfficial-source import checked

Dihydroxyacetone

Dihydroxyacetone. (a) Identity and specifications. The color additive dihydroxyacetone shall conform in identity and specifications to the requirements of § 73.1150 (a)(1) and (b). (b) Uses and restrictions. Dihydroxyacetone may be safely used in amounts consistent with good manufacturing practice in externally applied cosmetics intended solely or in part to impart a color to the human body. (c) Labeling requirements. The labeling of the color additive and any mixtures prepared therefrom intended solely or in part for coloring purposes shall conform to the requirements of § 70.25 of this chapter. (d) Exemption from certification. Certification of this color additive is not necessary for the protection of the public health and therefore batches thereof are exempt from the requirements of section 721(c) of the act.

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Regulatory decision and full conditions

Status
Permitted list with conditions
Legal role
Binding rule
Regulatory summary
Dihydroxyacetone. (a) Identity and specifications. The color additive dihydroxyacetone shall conform in identity and specifications to the requirements of § 73.1150 (a)(1) and (b). (b) Uses and restrictions. Dihydroxyacetone may be safely used in amounts consistent with good manufacturing practice in externally applied cosmetics intended solely or in part to impart a color to the human body. (c) Labeling requirements. The labeling of the color additive and any mixtures prepared therefrom intended solely or in part for coloring purposes shall conform to the requirements of § 70.25 of this chapter. (d) Exemption from certification. Certification of this color additive is not necessary for the protection of the public health and therefore batches thereof are exempt from the requirements of section 721(c) of the act.
Conditions and restrictions
Dihydroxyacetone. (a) Identity and specifications. The color additive dihydroxyacetone shall conform in identity and specifications to the requirements of § 73.1150 (a)(1) and (b). (b) Uses and restrictions. Dihydroxyacetone may be safely used in amounts consistent with good manufacturing practice in externally applied cosmetics intended solely or in part to impart a color to the human body. (c) Labeling requirements. The labeling of the color additive and any mixtures prepared therefrom intended solely or in part for coloring purposes shall conform to the requirements of § 70.25 of this chapter. (d) Exemption from certification. Certification of this color additive is not necessary for the protection of the public health and therefore batches thereof are exempt from the requirements of section 721(c) of the act.

Substance identity

Official source name
Dihydroxyacetone
CAS
96-26-4
EC
202-494-5
Identity mapping
name
Linked ingredient
DIHYDROXYACETONE
Search this identity across the siteCAS 96-26-4EC 202-494-5

Linked CosIng identity data

Names and aliases

DIHYDROXYACETONE

CosIng description: 1,3-Dihydroxyacetone

Recorded cosmetic function: HAIR DYEING, SKIN CONDITIONING - MISCELLANEOUS, TANNING

Function pages:HAIR DYEING, SKIN CONDITIONING - MISCELLANEOUS, TANNING

View the complete ingredient profile

Cross-market snapshot for this identity

Exact linked records currently present in this site. An absent market means no imported exact match, not permission to use the substance.

5 market datasets

United States

Current record
Permitted list with conditions

1 linked record · 1 with specific conditions

Open supporting record
PubChem 2D chemical structure for CAS 96-26-4
CAS 96-26-4PubChem CID 670

Verified chemistry for CAS 96-26-4

Dihydroxyacetone

Dihydroxyacetone is a ketotriose consisting of acetone bearing hydroxy substituents at positions 1 and 3. The simplest member of the class of ketoses and the parent of the class of glycerones. It has a role as a metabolite, an antifungal agent, a mouse metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a human metabolite. It is a primary alpha-hydroxy ketone and a ketotriose. — ChEBI

IUPAC name
1,3-dihydroxypropan-2-one
Molecular formula
C3H6O3
Molecular weight
90.08 g/mol
Exact mass
90.031694049 Da
Monoisotopic mass
90.031694049 Da
XLogP3
-1.4
Topological polar surface area
57.5 Ų
Molecular complexity
44.0
Formal charge
0
Hydrogen-bond donors
2
Hydrogen-bond acceptors
3
Rotatable bonds
2
Heavy atoms
6
Covalent units
1

Names and synonyms reported to PubChem

1,3-dihydroxyacetoneglyceroneChromelin1,3-Dihydroxy-2-propanoneOxantinTriuloseViticolorDihyxal
16 more reported names
OxatoneSolealOtan2-Propanone, 1,3-dihydroxy-1,3-Dihydroxypropanone1,3-Dihydroxydimethyl ketoneNSC-24343Dihydroxyacetone (USP)Dihydroxyacetone [USP]FEMA NO. 4033O10DDW6JOOCHEBI:160161,3 Dihydroxy 2 PropanoneGZE Tanning CreamDihydroxyacetone 10%RefChem:5755
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D pharmacophore features
5
3D rings
0
3D hydrophobes
0
3D acceptor features
3
3D donor features
2
3D anionic centres
0
3D cationic centres
0
3D conformers
10
Effective 3D rotors
2.0
Machine-readable structure identifiers
SMILES
C(C(=O)CO)O
InChI
InChI=1S/C3H6O3/c4-1-3(6)2-5/h4-5H,1-2H2
InChIKey
RXKJFZQQPQGTFL-UHFFFAOYSA-N

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Official source and provenance

Registered source
US FDA cosmetic ingredient framework
Source reference
21 CFR 73.2150
Source record ID
73.2150
Source version
2026-08-27
Source language
English
Translation status
Original is English
Source updated
2026-08-27
Snapshot checked
2026-08-30 04:30 UTC
Validation method
eCFR XML subpart/section parse; 99 records
SHA-256
25a55a997379f510077dfb234fe3f366e8a1429cec3d0b20fe4b60e2baf3c36d

Registered dataset notes

Dataset coverage
Federal ingredient framework, prohibited/restricted examples and color-additive rules
Authority note
The US has no EU-style general approved-ingredient catalogue; MoCRA listing is not approval
Inspect the exact official sourceRegulator guidance

How this record fits the market dataset

99
current United States records
90
records marked Permitted list with conditions
99
records from this source version
15
market records with CAS identity

Status distribution

Permitted list with conditions: 90Prohibited: 9

Condition text is present on 90 of 99 current records. An empty condition field is interpreted according to the record type above; it is never converted into an unrestricted-use claim.

United States market context

Complete enumerated federal ingredient rules

Coverage version: eCFR Title 21 issue date 27 August 2026

All cosmetic prohibitions/restrictions in Part 700 Subpart B and cosmetic-use colour additive listings in Parts 73, 74 and 82.

Verification checklist

  1. Search Part 700 and all relevant colour-additive parts.
  2. Confirm colour additive identity, permitted uses, limits and certification status.
  3. Assess safety and adulteration under the FD&C Act.
  4. Complete MoCRA facility/product, adverse-event and label obligations where applicable.

Official market sources

Verification workflow and record completeness

Before using this result in a compliance decision

  1. Confirm that “Dihydroxyacetone” and every CAS/EC identifier refer to the material in your supplier specification.
  2. Search Part 700 and all relevant colour-additive parts.
  3. Confirm colour additive identity, permitted uses, limits and certification status.
  4. Assess safety and adulteration under the FD&C Act.
  5. Complete MoCRA facility/product, adverse-event and label obligations where applicable.
  6. Document the source version and recheck the regulator before manufacture, notification or market placement.

Fields available in this record

  • Official substance nameAvailable
  • CASAvailable
  • ECAvailable
  • Separate condition textAvailable
  • Effective dateNot supplied
  • Snapshot hash and methodAvailable

Questions this page answers

This identity appears on a market positive list for the list function represented by the source record. Confirm that the intended function and product use fall within the list scope and every stated condition.

Positive-list presence is purpose-specific and is not blanket approval for every cosmetic use. FDA has no general approved-cosmetic-ingredient catalogue; absence from these sections is not approval or proof of safety.

The record cites 21 CFR 73.2150, source version 2026-08-27. Open the official source.

No. CAS helps resolve identity, but jurisdictions can classify the same substance differently and can apply different product scopes, limits, warnings and transition dates.

Stable citation

Dihydroxyacetone. 21 CFR 73.2150. United States. Source version 2026-08-27. CosIng Checker regulatory record: https://cosingchecker.com/regulations/us/records/731/

Cite the regulator as the legal authority. This page is a structured evidence index and verification aid, not a substitute for the official text or professional legal assessment.

Interpretation and limits for United States

This identity appears on a market positive list for the list function represented by the source record.

Confirm that the intended function and product use fall within the list scope and every stated condition.

How to interpret the legal role

The cited row forms part of a binding rule or legally incorporated list for this market.

Evidence on this page

  • Recorded outcome: Permitted list with conditions
  • Legal role: Binding rule
  • Source version: 2026-08-27

What it does not prove

FDA has no general approved-cosmetic-ingredient catalogue; absence from these sections is not approval or proof of safety.

Further authoritative substance research

These sources can add identity, safety, exposure or hazard context. A link is not evidence that the database contains this exact substance, and none of these sources overrides the market decision above.

Cosmetic Ingredient Review safety assessments

Expert Panel conclusions, assessed ingredient groups, use conditions, dates and report documents

Independent expert review considered by FDA; not a government approval or binding market rule

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FDA Global Substance Registration System

UNII identifiers, preferred names, substance types, codes and public substance relationships

Identity registry only; UNII availability does not imply FDA review or approval

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ILO/WHO International Chemical Safety Cards

Hazards, symptoms, first aid, storage, incompatibilities and physical properties for covered chemicals

International occupational chemical-safety reference; not cosmetic-use approval

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Japan NITE-CHRIP

Chemical identity, Japanese and foreign legal lists, GHS hazards and exposure-related information

Chemical-management evidence; cosmetic status remains governed by the applicable MHLW standard and market rules

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NIOSH Pocket Guide to Chemical Hazards

REL, PEL, IDLH, properties, exposure routes, symptoms, target organs, first aid and measurement methods for covered workplace chemicals

US occupational-health guidance and limits; not a cosmetic ingredient decision

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OECD eChemPortal

Gateway to authority-owned physical-property, fate, ecotoxicity, toxicity, exposure and GHS records

Discovery gateway; each linked authority remains responsible for its data

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US EPA CompTox CTX APIs

API key required for import

DTXSID identity, experimental and predicted properties, toxicity, bioactivity, exposure and environmental data

Scientific and computational evidence; predictions must remain labelled and do not determine cosmetic legality

Research this identity at the source