Why does CAS 96-26-4 appear in more than one EU cosmetic annex?

A substance identified by CAS 96-26-4 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts — for example, restricted under Annex III with specific conditions, while also appearing in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

How do I check if my formula contains a substance with CAS 96-26-4?

Use the INCI Checker on CosIng Checker with INCI names, CAS numbers or EC numbers. Paste CAS 96-26-4 to screen it directly, then review every linked annex record and supplier document.

CAS 1 record

CAS 96-26-4

Q: How do I use CAS 96-26-4 for compliance screening?

Cross-reference CAS 96-26-4 against your raw material specification sheets and CoA documents. When it appears in Annex II, verify absence. When it appears in Annex III, verify that concentration limits and product type conditions are met. All annex entries sharing this CAS number are listed on this page.

CAS 96-26-4 matches 1 EU annex record across Annex II–VI of Regulation 1223/2009.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 96-26-4

CAS 96-26-4PubChem CID 670

Dihydroxyacetone

Dihydroxyacetone is a ketotriose consisting of acetone bearing hydroxy substituents at positions 1 and 3. The simplest member of the class of ketoses and the parent of the class of glycerones. It has a role as a metabolite, an antifungal agent, a mouse metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a human metabolite. It is a primary alpha-hydroxy ketone and a ketotriose. — ChEBI

IUPAC name: 1,3-dihydroxypropan-2-one

Molecular formula: C3H6O3
Molecular weight: 90.08 g/mol
Exact mass: 90.031694049 Da
XLogP3: -1.4
Topological polar surface area: 57.5 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 3
Covalent units: 1
Defined stereocentres: 0

Also known as

1,3-dihydroxyacetoneglyceroneChromelin1,3-Dihydroxy-2-propanoneOxantinTriuloseViticolorDihyxal

16 more reported names

OxatoneSolealOtan2-Propanone, 1,3-dihydroxy-1,3-Dihydroxypropanone1,3-Dihydroxydimethyl ketoneNSC-24343Dihydroxyacetone (USP)Dihydroxyacetone [USP]FEMA NO. 4033O10DDW6JOOCHEBI:160161,3 Dihydroxy 2 PropanoneGZE Tanning CreamDihydroxyacetone 10%RefChem:5755

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:16016
ChEMBL:CHEMBL1229937
EPA DTXSID:DTXSID0025072
PubMed:38867704
PubMed:38582340
PubMed:34448514
PubMed:32506039
PubMed:31974165
PubMed:30959092
PubMed:29193605
PubMed:23220003
PubMed:23088097
PubMed:23067124
PubMed:23060553
PubMed:23017393

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Records for CAS 96-26-4

1 total

Annex

III

Entry

322

DIHYDROXYACETONE

1,3-Dihydroxy-2-propanone

(a) Hair dye substance in non-oxidative hair dye products (*) (b) Self-tanning products (*) (*) From 26 January 2022 hair dye and self-tanning products containing that substance and not complying with the restrictions…

202-494-5

Max concentration

How CAS 96-26-4 is used on this site

CAS 96-26-4 is the Chemical Abstracts Service identifier used to pin this page to a specific substance. In the current dataset, 1 EU annex record shares this identifier, which helps you cross-check whether the same substance appears under one regulatory context or several.

Use this page when a supplier specification, SDS or raw-material dossier gives you CAS 96-26-4 and you need to see every linked Annex II–VI record in one place. The entry cards above are the quickest route to concentration limits, warnings, annex placement and product-type conditions.

Frequently asked questions

A substance identified by CAS 96-26-4 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts. For example, a substance might be restricted under Annex III with specific conditions, and the same CAS might also appear in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

Cross-reference the CAS number against your raw material specification sheets and CoA documents. When a CAS appears in Annex II, verify absence. When it appears in Annex III, verify that concentration limits and product type conditions are met in your formulation. All annex entries sharing this CAS number are listed above.

A CAS number is assigned by the Chemical Abstracts Service (USA) and is globally recognised. An EC number is a European Commission identifier from inventories such as EINECS, ELINCS or the NLP list. Both identifiers may appear in EU cosmetic annex entries. Some substances have both, some have only one, and some older entries may have neither.

The INCI Checker accepts ingredient names, CAS numbers and EC numbers. Check this CAS number directly, then verify the result against supplier specification sheets and every linked annex condition.

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