Nickel(II) silicate [1]; Dinickel orthosilicate [2]; Nickel silicate (3:4) [3]; Silicic acid, nickel salt [4]; Trihydrogen hydroxybis[orthosilicato(4-)]trinickelate(3-) [5]
Listed by the Saudi Food and Drug Authority as prohibited in cosmetic products.
Regulatory decision and full conditions
- Status
- Prohibited
- Legal role
- Binding rule
- Regulatory summary
- Listed by the Saudi Food and Drug Authority as prohibited in cosmetic products.
- Conditions and restrictions
- A prohibition entry may contain no separate condition text because the regulatory outcome is the prohibition itself. Open the cited source and apply the market-wide requirements below.
Substance identity
- Official source name
- Nickel(II) silicate [1]; Dinickel orthosilicate [2]; Nickel silicate (3:4) [3]; Silicic acid, nickel salt [4]; Trihydrogen hydroxybis[orthosilicato(4-)]trinickelate(3-) [5]
- CAS
- 21784-78-1; 13775-54-7; 31748-25-1; 37321-15-6; 12519-85-6
- EC
- Not supplied in this source row
- Identity mapping
- standalone:official_sfda_record
Cross-market snapshot for this identity
Exact linked records currently present in this site. An absent market means no imported exact match, not permission to use the substance.
European Union
1 linked record
Open supporting recordNew Zealand
5 linked records
Open supporting recordIndia
2 linked records · 2 with specific conditions
Open supporting recordSaudi Arabia
Current record1 linked record
Open supporting recordVerified chemistry for CAS 12519-85-6
Trihydrogen hydroxybis[orthosilicato(4-)]trinickelate(3-)
- IUPAC name
- hydron;tris(nickel(2+));hydroxide;disilicate
- Molecular formula
- H4Ni3O9Si2
- Molecular weight
- 380.28 g/mol
- Exact mass
- 379.740853 Da
- Monoisotopic mass
- 377.74541 Da
- Topological polar surface area
- 185.0 Ų
- Molecular complexity
- 19.0
- Formal charge
- 0
- Hydrogen-bond donors
- 4
- Hydrogen-bond acceptors
- 9
- Rotatable bonds
- 0
- Heavy atoms
- 14
- Covalent units
- 9
Names and synonyms reported to PubChem
External database identifiers
- EPA DTXSID:DTXSID601028875
Advanced structure statistics
- Defined atom stereocentres
- 0
- Undefined atom stereocentres
- 0
- Defined bond stereocentres
- 0
- Undefined bond stereocentres
- 0
- 3D conformers
- 0
Machine-readable structure identifiers
- SMILES
[H+].[H+].[H+].[OH-].[O-][Si]([O-])([O-])[O-].[O-][Si]([O-])([O-])[O-].[Ni+2].[Ni+2].[Ni+2]- InChI
InChI=1S/3Ni.2O4Si.H2O/c;;;2*1-5(2,3)4;/h;;;;;1H2/q3*+2;2*-4;/p+2- InChIKey
BUISLYBGLXDIMJ-UHFFFAOYSA-P
Evidence from additional scientific databases
NIH PubChem PUG-View
Attributed physical-property, hazard, environmental and use annotations.
- Signal: Danger Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
- GHS Hazard Statements: H317: May cause an allergic skin reaction [Warning Sensitization, Skin]; H350i: May cause cancer by inhalation [Danger Carcinogenicity]; H372 **: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]; H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]; H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
- Precautionary Statement Codes: P203, P260, P261, P264, P270, P272, P273, P280, P302+P352, P318, P319, P321, P333+P317, P362+P364, P391, P405, and P501 (click each P-code to see the statement) Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Verified chemistry for CAS 13775-54-7
Dinickel orthosilicate
- IUPAC name
- bis(nickel(2+));silicate
- Molecular formula
- Ni2O4Si
- Molecular weight
- 209.47 g/mol
- Exact mass
- 207.827268 Da
- Monoisotopic mass
- 207.827268 Da
- Topological polar surface area
- 92.2 Ų
- Molecular complexity
- 19.0
- Formal charge
- 0
- Hydrogen-bond donors
- 0
- Hydrogen-bond acceptors
- 4
- Rotatable bonds
- 0
- Heavy atoms
- 7
- Covalent units
- 3
Names and synonyms reported to PubChem
External database identifiers
- EPA DTXSID:DTXSID20929885
Advanced structure statistics
- Defined atom stereocentres
- 0
- Undefined atom stereocentres
- 0
- Defined bond stereocentres
- 0
- Undefined bond stereocentres
- 0
- 3D conformers
- 0
Machine-readable structure identifiers
- SMILES
[O-][Si]([O-])([O-])[O-].[Ni+2].[Ni+2]- InChI
InChI=1S/2Ni.O4Si/c;;1-5(2,3)4/q2*+2;-4- InChIKey
AQQHXPJLFFJBCZ-UHFFFAOYSA-N
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Verified chemistry for CAS 21784-78-1
Nickel(2+) silicate
- IUPAC name
- nickel(2+) silicate
- Molecular formula
- NiO4Si-2
- Formula without charge
- NiO4Si
- Molecular weight
- 150.78 g/mol
- Exact mass
- 149.891927 Da
- Monoisotopic mass
- 149.891927 Da
- Topological polar surface area
- 92.2 Ų
- Molecular complexity
- 19.0
- Formal charge
- -2
- Hydrogen-bond donors
- 0
- Hydrogen-bond acceptors
- 4
- Rotatable bonds
- 0
- Heavy atoms
- 6
- Covalent units
- 2
Names and synonyms reported to PubChem
Advanced structure statistics
- Defined atom stereocentres
- 0
- Undefined atom stereocentres
- 0
- Defined bond stereocentres
- 0
- Undefined bond stereocentres
- 0
- 3D conformers
- 0
Machine-readable structure identifiers
- SMILES
[O-][Si]([O-])([O-])[O-].[Ni+2]- InChI
InChI=1S/Ni.O4Si/c;1-5(2,3)4/q+2;-4- InChIKey
BCDOSBUUKIYWJZ-UHFFFAOYSA-N
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Verified chemistry for CAS 31748-25-1
Silicic acid (H2SiO3), nickel(2+) salt (4:3)
- IUPAC name
- tetrakis(dioxido(oxo)silane);tris(nickel(2+))
- Molecular formula
- Ni3O12Si4-2
- Formula without charge
- Ni3O12Si4
- Molecular weight
- 480.41 g/mol
- Exact mass
- 479.648150 Da
- Monoisotopic mass
- 477.65271 Da
- Topological polar surface area
- 253.0 Ų
- Molecular complexity
- 18.0
- Formal charge
- -2
- Hydrogen-bond donors
- 0
- Hydrogen-bond acceptors
- 12
- Rotatable bonds
- 0
- Heavy atoms
- 19
- Covalent units
- 7
Names and synonyms reported to PubChem
External database identifiers
- EPA DTXSID:DTXSID601029304
Advanced structure statistics
- Defined atom stereocentres
- 0
- Undefined atom stereocentres
- 0
- Defined bond stereocentres
- 0
- Undefined bond stereocentres
- 0
- 3D conformers
- 0
Machine-readable structure identifiers
- SMILES
[O-][Si](=O)[O-].[O-][Si](=O)[O-].[O-][Si](=O)[O-].[O-][Si](=O)[O-].[Ni+2].[Ni+2].[Ni+2]- InChI
InChI=1S/3Ni.4O3Si/c;;;4*1-4(2)3/q3*+2;4*-2- InChIKey
ASXBPHUHJDRIAA-UHFFFAOYSA-N
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Verified chemistry for CAS 37321-15-6
silicic acid, nickel salt
- IUPAC name
- dioxido(oxo)silane;nickel(2+)
- Molecular formula
- NiO3Si
- Molecular weight
- 134.777 g/mol
- Exact mass
- 133.897012 Da
- Monoisotopic mass
- 133.897012 Da
- Topological polar surface area
- 63.2 Ų
- Molecular complexity
- 18.0
- Formal charge
- 0
- Hydrogen-bond donors
- 0
- Hydrogen-bond acceptors
- 3
- Rotatable bonds
- 0
- Heavy atoms
- 5
- Covalent units
- 2
Names and synonyms reported to PubChem
1 more reported name
External database identifiers
- EPA DTXSID:DTXSID701346345
Advanced structure statistics
- Defined atom stereocentres
- 0
- Undefined atom stereocentres
- 0
- Defined bond stereocentres
- 0
- Undefined bond stereocentres
- 0
- 3D conformers
- 0
Machine-readable structure identifiers
- SMILES
[O-][Si](=O)[O-].[Ni+2]- InChI
InChI=1S/Ni.O3Si/c;1-4(2)3/q+2;-2- InChIKey
FMQXRRZIHURSLR-UHFFFAOYSA-N
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Official source and provenance
- Registered source
- Saudi SFDA prohibited and restricted ingredient lists
- Source reference
- SFDA prohibited list, page 144, row 6
- Source record ID
prohibited-143-6- Source version
- live-snapshot-2026-08-30
- Source language
- English
- Translation status
- Original is English
- Snapshot checked
- 2026-08-30 05:18 UTC
- Validation method
- complete SFDA paginated HTML snapshot; strict page/row counts
- SHA-256
ceb6cc636e6b1f4b3013f88ce0297217b49d6194342c6ece5c03b1e04256d71a
Registered dataset notes
- Dataset coverage
- Prohibited and restricted substances with CAS, EC and conditions
- Authority note
- Official SFDA dated lists; version and hash each release
How this record fits the market dataset
Status distribution
Condition text is present on 0 of 2090 current records. An empty condition field is interpreted according to the record type above; it is never converted into an unrestricted-use claim.
Saudi Arabia market context
Complete official list index
Coverage version: SFDA live prohibited/restricted lists, snapshot 30 August 2026
Every page and entry in the public SFDA prohibited and restricted ingredient indexes; restricted detail pages remain the source for conditions.
Verification checklist
- Search names and CAS across both SFDA lists.
- Open the cited restricted-entry detail and apply every condition.
- Check current SFDA/GSO technical regulations and updates.
- Complete eCosma notification, label and responsible-party requirements.
Official market sources
- Saudi SFDA prohibited and restricted ingredient listsOfficial SFDA dated lists; version and hash each release
Verification workflow and record completeness
Before using this result in a compliance decision
- Confirm that “Nickel(II) silicate [1]; Dinickel orthosilicate [2]; Nickel silicate (3:4) [3]; Silicic acid, nickel salt [4]; Trihydrogen hydroxybis[orthosilicato(4-)]trinickelate(3-) [5]” and every CAS/EC identifier refer to the material in your supplier specification.
- Search names and CAS across both SFDA lists.
- Open the cited restricted-entry detail and apply every condition.
- Check current SFDA/GSO technical regulations and updates.
- Complete eCosma notification, label and responsible-party requirements.
- Document the source version and recheck the regulator before manufacture, notification or market placement.
Fields available in this record
- Official substance nameAvailable
- CASAvailable
- ECNot supplied
- Separate condition textNot present in source row
- Effective dateNot supplied
- Snapshot hash and methodAvailable
Questions this page answers
Stable citation
Nickel(II) silicate [1]; Dinickel orthosilicate [2]; Nickel silicate (3:4) [3]; Silicic acid, nickel salt [4]; Trihydrogen hydroxybis[orthosilicato(4-)]trinickelate(3-) [5]. SFDA prohibited list, page 144, row 6. Saudi Arabia. Source version live-snapshot-2026-08-30. CosIng Checker regulatory record: https://cosingchecker.com/regulations/sa/records/11015/
Cite the regulator as the legal authority. This page is a structured evidence index and verification aid, not a substitute for the official text or professional legal assessment.
Interpretation and limits for Saudi Arabia
This official record identifies the substance as prohibited for cosmetic use in the stated market scope.
Do not rely on a formulation containing this identity until the cited source, effective date and exact substance match have been verified.
How to interpret the legal role
The cited row forms part of a binding rule or legally incorporated list for this market.
Evidence on this page
- Recorded outcome: Prohibited
- Legal role: Binding rule
- Source version: live-snapshot-2026-08-30
What it does not prove
No list match is not permission; Gulf/SFDA product, claim, notification and technical requirements still apply.
Further authoritative substance research
These sources can add identity, safety, exposure or hazard context. A link is not evidence that the database contains this exact substance, and none of these sources overrides the market decision above.
Cosmetic Ingredient Review safety assessments
Expert Panel conclusions, assessed ingredient groups, use conditions, dates and report documents
Independent expert review considered by FDA; not a government approval or binding market rule
Research this identity at the sourceFDA Global Substance Registration System
UNII identifiers, preferred names, substance types, codes and public substance relationships
Identity registry only; UNII availability does not imply FDA review or approval
Research this identity at the sourceILO/WHO International Chemical Safety Cards
Hazards, symptoms, first aid, storage, incompatibilities and physical properties for covered chemicals
International occupational chemical-safety reference; not cosmetic-use approval
Research this identity at the sourceJapan NITE-CHRIP
Chemical identity, Japanese and foreign legal lists, GHS hazards and exposure-related information
Chemical-management evidence; cosmetic status remains governed by the applicable MHLW standard and market rules
Research this identity at the sourceNIOSH Pocket Guide to Chemical Hazards
REL, PEL, IDLH, properties, exposure routes, symptoms, target organs, first aid and measurement methods for covered workplace chemicals
US occupational-health guidance and limits; not a cosmetic ingredient decision
Research this identity at the sourceOECD eChemPortal
Gateway to authority-owned physical-property, fate, ecotoxicity, toxicity, exposure and GHS records
Discovery gateway; each linked authority remains responsible for its data
Research this identity at the sourceUS EPA CompTox CTX APIs
API key required for importDTXSID identity, experimental and predicted properties, toxicity, bioactivity, exposure and environmental data
Scientific and computational evidence; predictions must remain labelled and do not determine cosmetic legality
Research this identity at the source