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ProhibitedBinding ruleSAOriginal is EnglishOfficial-source import checked

1,4-Dihydroxybenzene (Hydroquinone), with the exception of entry 14 in Annex III

Listed by the Saudi Food and Drug Authority as prohibited in cosmetic products.

All Saudi Arabia recordsOpen ingredient profileCompare all marketsOpen official source

Regulatory decision and full conditions

Status
Prohibited
Legal role
Binding rule
Regulatory summary
Listed by the Saudi Food and Drug Authority as prohibited in cosmetic products.
Conditions and restrictions
A prohibition entry may contain no separate condition text because the regulatory outcome is the prohibition itself. Open the cited source and apply the market-wide requirements below.

Substance identity

Official source name
1,4-Dihydroxybenzene (Hydroquinone), with the exception of entry 14 in Annex III
CAS
123-31-9
EC
204-617-8
Identity mapping
cas_number
Linked ingredient
HYDROQUINONE
Search this identity across the siteCAS 123-31-9EC 204-617-8

Linked CosIng identity data

Names and aliases

HYDROQUINONE

CosIng description: Hydroquinone

EU inventory restriction note: II/1339 III/14

Recorded cosmetic function: LIGHT STABILIZER

Function pages:LIGHT STABILIZER

View the complete ingredient profile

Cross-market snapshot for this identity

Exact linked records currently present in this site. An absent market means no imported exact match, not permission to use the substance.

9 market datasets
PubChem 2D chemical structure for CAS 123-31-9
CAS 123-31-9PubChem CID 785

Verified chemistry for CAS 123-31-9

Hydroquinone

Hydroquinone is a benzenediol comprising benzene core carrying two hydroxy substituents para to each other. It has a role as an antioxidant, a cofactor, a carcinogenic agent, a mouse metabolite, a human xenobiotic metabolite, an Escherichia coli metabolite and a skin lightening agent. It is a benzenediol and a member of hydroquinones. — ChEBI

IUPAC name
benzene-1,4-diol
Molecular formula
C6H6O2
Molecular weight
110.11 g/mol
Exact mass
110.036779430 Da
Monoisotopic mass
110.036779430 Da
XLogP3
0.6
Topological polar surface area
40.5 Ų
Molecular complexity
54.0
Formal charge
0
Hydrogen-bond donors
2
Hydrogen-bond acceptors
2
Rotatable bonds
0
Heavy atoms
8
Covalent units
1

Names and synonyms reported to PubChem

1,4-benzenediol1,4-DihydroxybenzeneQuinolp-Hydroquinonep-Hydroxyphenolp-Benzenediolp-Dihydroxybenzene4-Hydroxyphenol
16 more reported names
hydroquinolBenzoquinolEldopaqueEldoquinHydroquinolePhiaquinTecquinolp-DioxybenzeneSolaquin forteIdrochinoneBenzohydroquinoneHidroquinoneArctuvinTequinolDihydroxybenzeneTenox HQ
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D pharmacophore features
3
3D rings
1
3D hydrophobes
0
3D acceptor features
0
3D donor features
2
3D anionic centres
0
3D cationic centres
0
3D conformers
1
Effective 3D rotors
0.0
Machine-readable structure identifiers
SMILES
C1=CC(=CC=C1O)O
InChI
InChI=1S/C6H6O2/c7-5-1-2-6(8)4-3-5/h1-4,7-8H
InChIKey
QIGBRXMKCJKVMJ-UHFFFAOYSA-N

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match785

Attributed physical-property, hazard, environmental and use annotations.

  • First Aid: Signs and Symptoms of Acute Hydroquinone Exposure: Signs and symptoms of acute exposure to hydroquinone may be severe and include dyspnea (shortness of breath), a sense of suffocation, increased respiratory rate, and respiratory failure. Pallor (paleness of the skin), cyanosis (blue tint to skin and mucous membranes), and cardiovascular collapse may occur. Neurologic effects include headache, tinnitus (ringing in the ears), dizziness, delirium, muscle twitching, tremor, and convulsions. Nausea, vomiting, and the production of green to brown-green urine may also occur. Hydroquinone may be irritating and corrosive to the skin, eyes, and mucous membranes. Jaundice (yellow tint to skin) may be noticed.; Emergency Life-Support Procedures: Acute exposure to hydroquinone may require decontamination and life support for the victims. Emergency personnel should wear protective clothing appropriate to the type and degree of contamination. Air-purifying or supplied-air respiratory equipment should also be worn, as necessary. Rescue vehicles should carry supplies such as plastic sheeting and disposable plastic bags to assist in preventing spread of contamination.; Inhalation Exposure:; 1. Move Source: CAMEO Chemicals
  • First Aid: (General first aid procedures); Eye: Irrigate immediately - If this chemical contacts the eyes, immediately wash (irrigate) the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately.; Skin: Water flush - If this chemical contacts the skin, flush the contaminated skin with water. Where there is evidence of skin irritation, get medical attention.; Breathing: Respiratory support; Swallow: Medical attention immediately - If this chemical has been swallowed, get medical attention immediately. Source: The National Institute for Occupational Safety and Health (NIOSH)
  • Signal: Danger Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • GHS Hazard Statements: H302: Harmful if swallowed [Warning Acute toxicity, oral]; H317: May cause an allergic skin reaction [Warning Sensitization, Skin]; H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]; H341: Suspected of causing genetic defects [Warning Germ cell mutagenicity]; H351: Suspected of causing cancer [Warning Carcinogenicity]; H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard] Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Precautionary Statement Codes: P203, P261, P264, P264+P265, P270, P272, P273, P280, P301+P317, P302+P352, P305+P354+P338, P317, P318, P321, P330, P333+P317, P362+P364, P391, P405, and P501 (click each P-code to see the statement) Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Note: This chemical does not meet GHS hazard criteria for < 0.1% (1 of 2485) of reports. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H302+H312 (17.7%): Harmful if swallowed or in contact with skin [Warning Acute toxicity, oral; acute toxicity, dermal]; H302 (99.7%): Harmful if swallowed [Warning Acute toxicity, oral]; H312 (17.7%): Harmful in contact with skin [Warning Acute toxicity, dermal]; H317 (> 99.9%): May cause an allergic skin reaction [Warning Sensitization, Skin]; H318 (99.9%): Causes serious eye damage [Danger Serious eye damage/eye irritation]; H341 (99.9%): Suspected of causing genetic defects [Warning Germ cell mutagenicity]; H351 (> 99.9%): Suspected of causing cancer [Warning Carcinogenicity]; H400 (> 99.9%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]; H410 (21.2%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P203, P261, P264, P264+P265, P270, P272, P273, P280, P301+P317, P302+P352, P305+P354+P338, P317, P318, P321, P330, P333+P317, P362+P364, P391, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 2485 reports by companies from 36 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 1 of 2485 reports by companies.; There are 35 notifications provided by 2484 of 2485 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: NITE-CMC
  • GHS Hazard Statements: H302: Harmful if swallowed [Warning Acute toxicity, oral]; H317: May cause an allergic skin reaction [Warning Sensitization, Skin]; H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]; H340: May cause genetic defects [Danger Germ cell mutagenicity]; H351: Suspected of causing cancer [Warning Carcinogenicity]; H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]; H373: May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]; H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]; H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Source: NITE-CMC
  • Precautionary Statement Codes: P203, P260, P261, P264, P264+P265, P270, P272, P273, P280, P301+P317, P302+P352, P305+P354+P338, P308+P316, P317, P318, P319, P321, P330, P333+P317, P362+P364, P391, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
  • GHS Hazard Statements: H316: Causes mild skin irritation [Warning Skin corrosion/irritation]; H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]; H336: May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure; Narcotic effects]; H341: Suspected of causing genetic defects [Warning Germ cell mutagenicity]; H373: May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure] Source: NITE-CMC
  • NFPA Health Rating: 2 - Materials that, under emergency conditions, can cause temporary incapacitation or residual injury. Source: Hazardous Substances Data Bank (HSDB)
  • NFPA Fire Rating: 1 - Materials that must be preheated before ignition can occur. Materials require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur. Source: Hazardous Substances Data Bank (HSDB)
  • NFPA Instability Rating: 0 - Materials that in themselves are normally stable, even under fire conditions. Source: Hazardous Substances Data Bank (HSDB)
  • Cosmetic Ingredient Review Conclusion: The CIR Expert Panel concluded that hydroquinone is safe at concentrations of less than or equal to 1% for cosmetic formulations designed for discontinuous, brief use followed by rinsing from the skin and hair. Hydroquinone is safe for use in nail adhesives and in artificial nail coatings, as a polymerization inhibitor, that are cured by LED light. Hydroquinone is unsafe for use in other leave-on cosmetic products. Source: Cosmetic Ingredient Review (CIR)
  • Cosmetic Ingredient Review Finding(s): The ingredient is unsafe for use in cosmetics Source: Cosmetic Ingredient Review (CIR)
  • Toxicity Summary: IDENTIFICATION AND USE: Hydroquinone (HQ) is an aromatic compound in the form of light tan to gray crystals. It is a high-volume commodity chemical used as a reducing agent, antioxidant, polymerization inhibitor, chemical stabilizer, chemical intermediate, and photographic reducer and developer. It is also used in skin lighteners, in cosmetics, hair dye, glue, and a medication to treat dyschromias. HUMAN EXPOSURE: A great deal of research has been conducted with HQ because it is a metabolite of benzene. In workers engaged in the manufacture, HQ dust oxidizes to brown benzoquinone. This material causes pigmentation of the eye and, in some cases, permanent corneal damage. There are reported cases of keratitis and discoloration of the conjunctiva among men exposed to concentrations ranging from 10 to 30 mg of vapor or dust of HQ per cubic meter of air. Ingestion of 1 g by an adult has caused dizziness, sense of suffocation, increased rate of respiration, vomiting, pallor, muscular twitching, headache, dyspnea, cyanosis and collapse and eventually death due to respiratory failure. Upon ingestion urine is green or brownish-green in color and continues to darken on standing. Five hundred Source: Hazardous Substances Data Bank (HSDB)
  • Toxicity Summary: No significant toxicity has been found with the topical use of the hydroquinone cream.; Some studies report malignancies in animals treated for an extended period with large oral doses.; Hydroquinone in the Environment; In the environment, hydroquinone is a chemical and can be toxic in human and industrial activities by promoting the generation of reactive oxygen species, oxidative stress, and hence the potential for DNA damage. It is a major benzene metabolite and is known to be hepatotoxic and carcinogenic in these settings. Some studies suggest it can promote tumor cell growth and suppress the immune response. It is used in photography and is present in dyes, paints, varnishes oils, and motor fuels. In its oxidized form, it is more toxic and less degradable. It demonstrates high toxicity to aquatic organisms and rodents and may induce leukemia, renal tubular cell tumors, and liver cancer. It has also been found to influence immune cell responses and cause an increase in an allergic reaction by increasing interleukin-4 production and immunoglobulin E levels. Source: StatPearls
  • Environmental Bioconcentration: An estimated BCF of 3 was calculated in fish for hydroquinone(SRC), using a log Kow of 0.59(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC). A bioaccumulation factor of 40 was measured using Golden ide fish (Leuciscus idus melanotus) exposed for 3 days to 0.05 mg/L hydroquinone(4,5). Experimental 24-hour bioaccumulation factors in alga were 40 and 65 for hydroquinone(4-6). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 240(SRC), determined from a strucure estimation method(2), indicates that hydroquinone is expected to have moderate mobility in soil(SRC). Volatilization of hydroquinone from moist soil surfaces is not expected to be an important fate process(SRC) given an estimated Henry's Law constant of 4.7X10-11 atm-cu m/mole(SRC), derived from its vapor pressure, 2.4X10-5 mm Hg(3), and water solubility, 7.2X10+4 mg/L(4). Hydroquinone is not expected to volatilize from dry soil surfaces(SRC) based upon its vapor pressure(3). The compound may be removed from soil by oxidation processes(5,6) or by direct photolysis on the surface(7,8). In a survey of standardized tests, hydroquinone was found to biodegrade in the coupled units test, the Zahn-Wellens test, the MITI test, the Sturm test, the AFNOR test, the OECD screening test and the closed bottle test, although its biodegradation is likely to be strongly concentration-dependent. It may be inhibitory at high concentration(9,10). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 240(SRC), determined from a structure estimation method(2), indicates that hydroquinone is expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is not expected(3) based upon an estimated Henry's Law constant of 4.7X10-11 atm-cu m/mole(SRC), derived from its vapor pressure, 2.4X10-5 mm Hg(4), and water solubility, 7.2X10+4 mg/L(5). According to a classification scheme(6), an estimated BCF of 3(SRC), from its log Kow(7) and a regression-derived equation(2), suggests the potential for bioconcentration in aquatic organisms is low(SRC). In a survey of standardized tests, hydroquinone was found to biodegrade in the coupled units test, the Zahn-Wellens test, the MITI test, the Sturm test, the AFNOR test, the OECD screening test and the closed bottle test, although its biodegradation is likely to be strongly concentration-dependent. It may be inhibitory at high concentration(8,9). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), hydroquinone, which has a vapor pressure of 2.4X10-5 mm Hg at 25 °C(2), will exist in both the vapor and particulate phases in the ambient atmosphere. Vapor-phase hydroquinone is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 17 hrs(SRC), calculated from its rate constant of 2.3X10-11 cu cm/molecule-sec at 25 °C(SRC) that was derived using a structure estimation method(3). Particulate-phase hydroquinone may be removed from the air by wet and dry deposition(SRC). The water solubility of hydroquinone, 72,000 mg/L at 25 °C(4), indicates that it may undergo atmospheric removal by wet deposition processes(SRC). It may also be removed from the atmosphere by a gas-phase reaction with nitrate radicals, an important nighttime oxidant(3). Hydroquinone contains chromophores that absorb at wavelengths >290 nm(5) and, therefore, may be susceptible to direct photolysis by sunlight(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Industry Uses: Polymerization promoter; Solvent; Antioxidant; Not Known or Reasonably Ascertainable; Corrosion inhibitor; Intermediate; Photosensitive agent Source: EPA Chemical Data Reporting (CDR)
  • Cosmetic Ingredient Review Link: CIR ingredient: Hydroquinone Source: Cosmetic Ingredient Review (CIR)
  • Uses: Hydroquinone is used as a developing agent in black-and-white photography, lithography, and x-ray films. It is also used as an intermediate to produce antioxidants for rubber and food. It is added to a number of industrial monomers to inhibit polymerization during shipping, storage, and processing. Source: EPA Hazardous Air Pollutants
  • Sources/Uses: Used as a developer (photographic & lithographic), stabilizer in paints and oils, polymerization inhibitor, and chemical intermediate. [ACGIH] Used as a photo developer, oil and fat antioxidant, chemical intermediate, topical medication, and inhibitor of vinyl acetate and acrylic polymerization; [HSDB] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Industrial Processes with risk of exposure: Plastic Composites Manufacturing [Category: Industry]; Photographic Processing [Category: Other] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Uses: The largest demand for hydroquinone is as a photographic developer, principally for black-and-white film, lithography, photochemical machining, microfilm, and X-ray film. ... The second largest consumer of hydroquinone is the rubber industry, which requires hydroquinone for the production of antioxidants and antiozonants. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: ... Used extensively in the vinyl monomer industry to inhibit free-radical polymerization during both processing and storage ... Used as stabilizers for unsaturated polyester resins. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Hydroquinone is an aromatic compound that functions in cosmetics as an antioxidant, fragrance, reducing agent, or polymerization inhibitor... Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Hydroquinone (U.S.P. grade) ... /is/ used in topical formulations as /a/ skin bleaching and depigmenting agent. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: For more Uses (Complete) data for HYDROQUINONE (12 total), please visit the HSDB record page. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Hydroquinone has a variety of uses principally associated with its action as a reducing agent which is soluble in water. It is a major component in most photographic developers where, with the compound Metol, it reduces silver halides to elemental silver. In human medicine, hydroquinone is used as a topical application in skin whitening to reduce the color of skin. Source: Toxin and Toxin Target Database (T3DB)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Official source and provenance

Registered source
Saudi SFDA prohibited and restricted ingredient lists
Source reference
SFDA prohibited list, page 134, row 5
Source record ID
prohibited-133-5
Source version
live-snapshot-2026-08-30
Source language
English
Translation status
Original is English
Snapshot checked
2026-08-30 05:18 UTC
Validation method
complete SFDA paginated HTML snapshot; strict page/row counts
SHA-256
ceb6cc636e6b1f4b3013f88ce0297217b49d6194342c6ece5c03b1e04256d71a

Registered dataset notes

Dataset coverage
Prohibited and restricted substances with CAS, EC and conditions
Authority note
Official SFDA dated lists; version and hash each release
Inspect the exact official sourceRegulator guidance

How this record fits the market dataset

2090
current Saudi Arabia records
1726
records marked Prohibited
2090
records from this source version
1991
market records with CAS identity

Status distribution

Prohibited: 1726Restricted: 364

Condition text is present on 0 of 2090 current records. An empty condition field is interpreted according to the record type above; it is never converted into an unrestricted-use claim.

Saudi Arabia market context

Complete official list index

Coverage version: SFDA live prohibited/restricted lists, snapshot 30 August 2026

Every page and entry in the public SFDA prohibited and restricted ingredient indexes; restricted detail pages remain the source for conditions.

Verification checklist

  1. Search names and CAS across both SFDA lists.
  2. Open the cited restricted-entry detail and apply every condition.
  3. Check current SFDA/GSO technical regulations and updates.
  4. Complete eCosma notification, label and responsible-party requirements.

Official market sources

Verification workflow and record completeness

Before using this result in a compliance decision

  1. Confirm that “1,4-Dihydroxybenzene (Hydroquinone), with the exception of entry 14 in Annex III” and every CAS/EC identifier refer to the material in your supplier specification.
  2. Search names and CAS across both SFDA lists.
  3. Open the cited restricted-entry detail and apply every condition.
  4. Check current SFDA/GSO technical regulations and updates.
  5. Complete eCosma notification, label and responsible-party requirements.
  6. Document the source version and recheck the regulator before manufacture, notification or market placement.

Fields available in this record

  • Official substance nameAvailable
  • CASAvailable
  • ECAvailable
  • Separate condition textNot present in source row
  • Effective dateNot supplied
  • Snapshot hash and methodAvailable

Questions this page answers

This official record identifies the substance as prohibited for cosmetic use in the stated market scope. Do not rely on a formulation containing this identity until the cited source, effective date and exact substance match have been verified.

A prohibition entry may contain no separate condition text because the regulatory outcome is the prohibition itself. No list match is not permission; Gulf/SFDA product, claim, notification and technical requirements still apply.

The record cites SFDA prohibited list, page 134, row 5, source version live-snapshot-2026-08-30. Open the official source.

No. CAS helps resolve identity, but jurisdictions can classify the same substance differently and can apply different product scopes, limits, warnings and transition dates.

Stable citation

1,4-Dihydroxybenzene (Hydroquinone), with the exception of entry 14 in Annex III. SFDA prohibited list, page 134, row 5. Saudi Arabia. Source version live-snapshot-2026-08-30. CosIng Checker regulatory record: https://cosingchecker.com/regulations/sa/records/10914/

Cite the regulator as the legal authority. This page is a structured evidence index and verification aid, not a substitute for the official text or professional legal assessment.

Interpretation and limits for Saudi Arabia

This official record identifies the substance as prohibited for cosmetic use in the stated market scope.

Do not rely on a formulation containing this identity until the cited source, effective date and exact substance match have been verified.

How to interpret the legal role

The cited row forms part of a binding rule or legally incorporated list for this market.

Evidence on this page

  • Recorded outcome: Prohibited
  • Legal role: Binding rule
  • Source version: live-snapshot-2026-08-30

What it does not prove

No list match is not permission; Gulf/SFDA product, claim, notification and technical requirements still apply.

Further authoritative substance research

These sources can add identity, safety, exposure or hazard context. A link is not evidence that the database contains this exact substance, and none of these sources overrides the market decision above.

Cosmetic Ingredient Review safety assessments

Expert Panel conclusions, assessed ingredient groups, use conditions, dates and report documents

Independent expert review considered by FDA; not a government approval or binding market rule

Research this identity at the source

FDA Global Substance Registration System

UNII identifiers, preferred names, substance types, codes and public substance relationships

Identity registry only; UNII availability does not imply FDA review or approval

Research this identity at the source

ILO/WHO International Chemical Safety Cards

Hazards, symptoms, first aid, storage, incompatibilities and physical properties for covered chemicals

International occupational chemical-safety reference; not cosmetic-use approval

Research this identity at the source

Japan NITE-CHRIP

Chemical identity, Japanese and foreign legal lists, GHS hazards and exposure-related information

Chemical-management evidence; cosmetic status remains governed by the applicable MHLW standard and market rules

Research this identity at the source

NIOSH Pocket Guide to Chemical Hazards

REL, PEL, IDLH, properties, exposure routes, symptoms, target organs, first aid and measurement methods for covered workplace chemicals

US occupational-health guidance and limits; not a cosmetic ingredient decision

Research this identity at the source

OECD eChemPortal

Gateway to authority-owned physical-property, fate, ecotoxicity, toxicity, exposure and GHS records

Discovery gateway; each linked authority remains responsible for its data

Research this identity at the source

US EPA CompTox CTX APIs

API key required for import

DTXSID identity, experimental and predicted properties, toxicity, bioactivity, exposure and environmental data

Scientific and computational evidence; predictions must remain labelled and do not determine cosmetic legality

Research this identity at the source