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ProhibitedBinding ruleSAOriginal is EnglishOfficial-source import checked

Simazine

Listed by the Saudi Food and Drug Authority as prohibited in cosmetic products.

All Saudi Arabia recordsCompare all marketsOpen official source

Regulatory decision and full conditions

Status
Prohibited
Legal role
Binding rule
Regulatory summary
Listed by the Saudi Food and Drug Authority as prohibited in cosmetic products.
Conditions and restrictions
A prohibition entry may contain no separate condition text because the regulatory outcome is the prohibition itself. Open the cited source and apply the market-wide requirements below.

Substance identity

Official source name
Simazine
CAS
122-34-9
EC
Not supplied in this source row
Identity mapping
standalone:official_sfda_record
Search this identity across the siteCAS 122-34-9

Cross-market snapshot for this identity

Exact linked records currently present in this site. An absent market means no imported exact match, not permission to use the substance.

9 market datasets
PubChem 2D chemical structure for CAS 122-34-9
CAS 122-34-9PubChem CID 5216

Verified chemistry for CAS 122-34-9

Simazine

IUPAC name
6-chloro-2-N,4-N-diethyl-1,3,5-triazine-2,4-diamine
Molecular formula
C7H12ClN5
Molecular weight
201.66 g/mol
Exact mass
201.0781231 Da
Monoisotopic mass
201.0781231 Da
XLogP3
2.2
Topological polar surface area
62.7 Ų
Molecular complexity
131.0
Formal charge
0
Hydrogen-bond donors
2
Hydrogen-bond acceptors
5
Rotatable bonds
4
Heavy atoms
13
Covalent units
1

Names and synonyms reported to PubChem

GesatopPrincepSimanexGesapunPrimatol SAquazineBatazinaHerbazin
16 more reported names
SymazineTafazineTaphazineBitemolHerbexHerboxyPrintopRadoconRadokorSimadexZeapurHerbazin 50Aktinit SHungazin DTPremazineGesaran
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D pharmacophore features
5
3D rings
1
3D hydrophobes
0
3D acceptor features
0
3D donor features
2
3D anionic centres
0
3D cationic centres
2
3D conformers
10
Effective 3D rotors
4.0
Machine-readable structure identifiers
SMILES
CCNC1=NC(=NC(=N1)Cl)NCC
InChI
InChI=1S/C7H12ClN5/c1-3-9-6-11-5(8)12-7(13-6)10-4-2/h3-4H2,1-2H3,(H2,9,10,11,12,13)
InChIKey
ODCWYMIRDDJXKW-UHFFFAOYSA-N

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match5216

Attributed physical-property, hazard, environmental and use annotations.

  • First Aid: EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.; SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.; INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) shou Source: CAMEO Chemicals
  • Signal: Warning Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • GHS Hazard Statements: H351: Suspected of causing cancer [Warning Carcinogenicity]; H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]; H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Precautionary Statement Codes: P203, P273, P280, P318, P391, P405, and P501 (click each P-code to see the statement) Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Signal: Warning Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H302 (51.7%): Harmful if swallowed [Warning Acute toxicity, oral]; H319 (51.7%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H351 (100%): Suspected of causing cancer [Warning Carcinogenicity]; H400 (100%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]; H410 (100%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P203, P264, P264+P265, P270, P273, P280, P301+P317, P305+P351+P338, P318, P330, P337+P317, P391, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 87 reports by companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: NITE-CMC
  • GHS Hazard Statements: H320: Causes eye irritation [Warning Serious eye damage/eye irritation]; H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]; H336: May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure; Narcotic effects]; H351: Suspected of causing cancer [Warning Carcinogenicity]; H361: Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]; H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]; H373: May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]; H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]; H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Source: NITE-CMC
  • Precautionary Statement Codes: P203, P260, P261, P264, P264+P265, P270, P271, P273, P280, P304+P340, P305+P351+P338, P318, P319, P337+P317, P391, P403+P233, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
  • Signal: Warning Source: NITE-CMC
  • GHS Hazard Statements: H317: May cause an allergic skin reaction [Warning Sensitization, Skin]; H320: Causes eye irritation [Warning Serious eye damage/eye irritation]; H373: May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure] Source: NITE-CMC
  • Environmental Bioconcentration: BCFs of 2.3 to 3.2 and 9.7 to 14.6 were measured in carp at 0.1 and 0.01 mg/L, respectively(1). BCFs up to 55 have been reported in the literature(2). BCFs of 0.76 to 0.95 were measured in green sunfish (Lepomas cyanellus)(3), <1 in bluegill sunfish(4), and 5 and 2, in bluegill sunfish and catfish, respectively(2). According to a classification scheme(5), these BCFs suggest the bioconcentration in aquatic organisms is low to moderate(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: TERRESTRIAL FATE: Based on a classification scheme(1), Koc values ranging from 78 to 3,559(2,3), indicate that simazine is expected to have high to slight mobility in soil(SRC). Increasing sorption has been observed with decreasing pH(4). Volatilization of simazine from moist soil surfaces is not expected to be important(SRC) given an estimated Henry's Law constant of 9.4X10-10 atm-cu m/mole(SRC), derived from its vapor pressure, 2.2X10-8 mm Hg(5) and water solubility of 6.2 mg/L(5). Simazine is not expected to volatilize from dry soil surfaces based on its vapor pressure(5). The half-lives for degradation (purportedly mainly soil-catalyzed hydrolysis) of simazine in Hatzenbuhl soil at pH 4.8 and Neuhofen soil at pH 6.5 are 45 and 100 days, respectively(6). Estimated soil hydrolysis half-lives in Wongan Hills loamy sand at 9, 20, and 28 °C were 144, 37, and 21 days, respectively(7). Humic and fulvic acids have been observed to favor the hydrolysis of triazine molecules(8). Microbial breakdown in soil results in degradation of simazine at very variable rates, half-lives range from 27 to 102 days (median 49 days); temperature and moisture are the main factors affecting the rates(5). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: TERRESTRIAL FATE: It has been reported that simazine and other s-triazines can be utilized by certain soil microorganisms as a source of energy(1). Microbial degradation products of simazine in soil include 2-chloro-4-amino-6-ethylamino-1,3,5-triazine and 2,4-dihydroxy-6-amino-1,3,5-triazine(1). Mineralization of 10.4% of (14)C-labeled simazine in 110 days has been reported in a clay-lime soil; no degradation of simazine was detected in a soil suspension test without the addition of glucose as an energy source suggesting that degradation of simazine in these soil experiments was due to co-metabolism(2). Reported persistence of simazine in soil varies from a half-life of <1 month(3) to no degradation being observed in 3.5 months(4). The amount of organic matter in the soil may have a significant effect on the persistence of simazine(3). Additions of 1%, 5%, and 10% leaf compost to soil gave simazine half-lives of about 140, 60, and 40 days, respectively(3). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: AQUATIC FATE: Based on a classification scheme(1), Koc values ranging from 78 to 3,559(2,3), indicate that some adsorption of simazine to suspended solids and sediment in the water column is expected(SRC). Increasing sorption has been observed with decreasing pH(14). Simazine is not expected to volatilize from water surfaces(4) based on an estimated Henry's Law constant of 9.4X10-10 atm-cu m/mole(SRC), derived from its vapor pressure, 2.2X10-8 mm Hg(5) and water solubility of 6.2 mg/L(5). According to a classification scheme(6), BCFs ranging from <1 to 55(7-9) suggest bioconcentration in aquatic organisms is low to moderate(SRC). Simazine is stable at pH 7 and 9 but the hydrolysis half-life at pH 5 and 25 °C is 70 days(10). The product of simazine hydrolysis is 2-hydroxy-4,6-bis(ethylamino)-1,3,5-triazine(10). Humic and fulvic acids have been observed to favor the hydrolysis of triazine molecules(11). Biodegradation in surface water samples from three ponds in Nagoya City, Japan, ranged from 0 to 30% after four days incubation; after 7 days incubation, biodegradation ranged from 0 to 24%(12). In Po River water, an initial simazine concentration of 5 ug/L was reduced to 3.1 and 2.5 Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: AQUATIC FATE: Dissipation of simazine in pond and lake water was variable, with half-lives ranging from 50 to 700 days. The degradation compound G-28279 /1,3,5-triazine-2,4-diamine, 6-chloro-N-ethyl-; CAS Number 1007-28-9/ was identified in lake water samples. Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: For more Environmental Fate (Complete) data for SIMAZINE (6 total), please visit the HSDB record page. Source: Hazardous Substances Data Bank (HSDB)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Official source and provenance

Registered source
Saudi SFDA prohibited and restricted ingredient lists
Source reference
SFDA prohibited list, page 101, row 6
Source record ID
prohibited-100-6
Source version
live-snapshot-2026-08-30
Source language
English
Translation status
Original is English
Snapshot checked
2026-08-30 05:18 UTC
Validation method
complete SFDA paginated HTML snapshot; strict page/row counts
SHA-256
ceb6cc636e6b1f4b3013f88ce0297217b49d6194342c6ece5c03b1e04256d71a

Registered dataset notes

Dataset coverage
Prohibited and restricted substances with CAS, EC and conditions
Authority note
Official SFDA dated lists; version and hash each release
Inspect the exact official sourceRegulator guidance

How this record fits the market dataset

2090
current Saudi Arabia records
1726
records marked Prohibited
2090
records from this source version
1991
market records with CAS identity

Status distribution

Prohibited: 1726Restricted: 364

Condition text is present on 0 of 2090 current records. An empty condition field is interpreted according to the record type above; it is never converted into an unrestricted-use claim.

Saudi Arabia market context

Complete official list index

Coverage version: SFDA live prohibited/restricted lists, snapshot 30 August 2026

Every page and entry in the public SFDA prohibited and restricted ingredient indexes; restricted detail pages remain the source for conditions.

Verification checklist

  1. Search names and CAS across both SFDA lists.
  2. Open the cited restricted-entry detail and apply every condition.
  3. Check current SFDA/GSO technical regulations and updates.
  4. Complete eCosma notification, label and responsible-party requirements.

Official market sources

Verification workflow and record completeness

Before using this result in a compliance decision

  1. Confirm that “Simazine” and every CAS/EC identifier refer to the material in your supplier specification.
  2. Search names and CAS across both SFDA lists.
  3. Open the cited restricted-entry detail and apply every condition.
  4. Check current SFDA/GSO technical regulations and updates.
  5. Complete eCosma notification, label and responsible-party requirements.
  6. Document the source version and recheck the regulator before manufacture, notification or market placement.

Fields available in this record

  • Official substance nameAvailable
  • CASAvailable
  • ECNot supplied
  • Separate condition textNot present in source row
  • Effective dateNot supplied
  • Snapshot hash and methodAvailable

Questions this page answers

This official record identifies the substance as prohibited for cosmetic use in the stated market scope. Do not rely on a formulation containing this identity until the cited source, effective date and exact substance match have been verified.

A prohibition entry may contain no separate condition text because the regulatory outcome is the prohibition itself. No list match is not permission; Gulf/SFDA product, claim, notification and technical requirements still apply.

The record cites SFDA prohibited list, page 101, row 6, source version live-snapshot-2026-08-30. Open the official source.

No. CAS helps resolve identity, but jurisdictions can classify the same substance differently and can apply different product scopes, limits, warnings and transition dates.

Stable citation

Simazine. SFDA prohibited list, page 101, row 6. Saudi Arabia. Source version live-snapshot-2026-08-30. CosIng Checker regulatory record: https://cosingchecker.com/regulations/sa/records/10605/

Cite the regulator as the legal authority. This page is a structured evidence index and verification aid, not a substitute for the official text or professional legal assessment.

Interpretation and limits for Saudi Arabia

This official record identifies the substance as prohibited for cosmetic use in the stated market scope.

Do not rely on a formulation containing this identity until the cited source, effective date and exact substance match have been verified.

How to interpret the legal role

The cited row forms part of a binding rule or legally incorporated list for this market.

Evidence on this page

  • Recorded outcome: Prohibited
  • Legal role: Binding rule
  • Source version: live-snapshot-2026-08-30

What it does not prove

No list match is not permission; Gulf/SFDA product, claim, notification and technical requirements still apply.

Further authoritative substance research

These sources can add identity, safety, exposure or hazard context. A link is not evidence that the database contains this exact substance, and none of these sources overrides the market decision above.

Cosmetic Ingredient Review safety assessments

Expert Panel conclusions, assessed ingredient groups, use conditions, dates and report documents

Independent expert review considered by FDA; not a government approval or binding market rule

Research this identity at the source

FDA Global Substance Registration System

UNII identifiers, preferred names, substance types, codes and public substance relationships

Identity registry only; UNII availability does not imply FDA review or approval

Research this identity at the source

ILO/WHO International Chemical Safety Cards

Hazards, symptoms, first aid, storage, incompatibilities and physical properties for covered chemicals

International occupational chemical-safety reference; not cosmetic-use approval

Research this identity at the source

Japan NITE-CHRIP

Chemical identity, Japanese and foreign legal lists, GHS hazards and exposure-related information

Chemical-management evidence; cosmetic status remains governed by the applicable MHLW standard and market rules

Research this identity at the source

NIOSH Pocket Guide to Chemical Hazards

REL, PEL, IDLH, properties, exposure routes, symptoms, target organs, first aid and measurement methods for covered workplace chemicals

US occupational-health guidance and limits; not a cosmetic ingredient decision

Research this identity at the source

OECD eChemPortal

Gateway to authority-owned physical-property, fate, ecotoxicity, toxicity, exposure and GHS records

Discovery gateway; each linked authority remains responsible for its data

Research this identity at the source

US EPA CompTox CTX APIs

API key required for import

DTXSID identity, experimental and predicted properties, toxicity, bioactivity, exposure and environmental data

Scientific and computational evidence; predictions must remain labelled and do not determine cosmetic legality

Research this identity at the source