Skip to main content
CosIng Checker
CosIng Checker
EU cosmetic ingredients, restrictions and safety
Login
CAS 1 record

CAS 122-34-9

CAS 122-34-9 matches 1 EU annex record across Annex II–VI of Regulation 1223/2009.

Check this CAS numberBrowse annexes

Chemical identity and properties

PubChem 2D chemical structure for CAS 122-34-9
CAS 122-34-9PubChem CID 5216

Simazine

Simazine is a diamino-1,3,5-triazine that is N,N'-diethyl-1,3,5-triazine-2,4-diamine substituted by a chloro group at position 6. It has a role as a herbicide, a xenobiotic and an environmental contaminant. It is a chloro-1,3,5-triazine and a diamino-1,3,5-triazine. — ChEBI

IUPAC name
6-chloro-2-N,4-N-diethyl-1,3,5-triazine-2,4-diamine
Molecular formula
C7H12ClN5
Molecular weight
201.66 g/mol
Exact mass
201.0781231 Da
XLogP3
2.2
Topological polar surface area
62.7 Ų
Hydrogen-bond donors
2
Hydrogen-bond acceptors
5
Covalent units
1
Defined stereocentres
0

Also known as

GesatopPrincepSimanexGesapunPrimatol SAquazineBatazinaHerbazin
16 more reported names
SymazineTafazineTaphazineBitemolHerbexHerboxyPrintopRadoconRadokorSimadexZeapurHerbazin 50Aktinit SHungazin DTPremazineGesaran
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match5216

Attributed physical-property, hazard, environmental and use annotations.

  • First Aid: EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.; SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.; INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) shou Source: CAMEO Chemicals
  • Signal: Warning Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • GHS Hazard Statements: H351: Suspected of causing cancer [Warning Carcinogenicity]; H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]; H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Precautionary Statement Codes: P203, P273, P280, P318, P391, P405, and P501 (click each P-code to see the statement) Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Signal: Warning Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H302 (51.7%): Harmful if swallowed [Warning Acute toxicity, oral]; H319 (51.7%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H351 (100%): Suspected of causing cancer [Warning Carcinogenicity]; H400 (100%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]; H410 (100%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P203, P264, P264+P265, P270, P273, P280, P301+P317, P305+P351+P338, P318, P330, P337+P317, P391, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 87 reports by companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: NITE-CMC
  • GHS Hazard Statements: H320: Causes eye irritation [Warning Serious eye damage/eye irritation]; H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]; H336: May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure; Narcotic effects]; H351: Suspected of causing cancer [Warning Carcinogenicity]; H361: Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]; H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]; H373: May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]; H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]; H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Source: NITE-CMC
  • Precautionary Statement Codes: P203, P260, P261, P264, P264+P265, P270, P271, P273, P280, P304+P340, P305+P351+P338, P318, P319, P337+P317, P391, P403+P233, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
  • Signal: Warning Source: NITE-CMC
  • GHS Hazard Statements: H317: May cause an allergic skin reaction [Warning Sensitization, Skin]; H320: Causes eye irritation [Warning Serious eye damage/eye irritation]; H373: May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure] Source: NITE-CMC
  • Environmental Bioconcentration: BCFs of 2.3 to 3.2 and 9.7 to 14.6 were measured in carp at 0.1 and 0.01 mg/L, respectively(1). BCFs up to 55 have been reported in the literature(2). BCFs of 0.76 to 0.95 were measured in green sunfish (Lepomas cyanellus)(3), <1 in bluegill sunfish(4), and 5 and 2, in bluegill sunfish and catfish, respectively(2). According to a classification scheme(5), these BCFs suggest the bioconcentration in aquatic organisms is low to moderate(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: TERRESTRIAL FATE: Based on a classification scheme(1), Koc values ranging from 78 to 3,559(2,3), indicate that simazine is expected to have high to slight mobility in soil(SRC). Increasing sorption has been observed with decreasing pH(4). Volatilization of simazine from moist soil surfaces is not expected to be important(SRC) given an estimated Henry's Law constant of 9.4X10-10 atm-cu m/mole(SRC), derived from its vapor pressure, 2.2X10-8 mm Hg(5) and water solubility of 6.2 mg/L(5). Simazine is not expected to volatilize from dry soil surfaces based on its vapor pressure(5). The half-lives for degradation (purportedly mainly soil-catalyzed hydrolysis) of simazine in Hatzenbuhl soil at pH 4.8 and Neuhofen soil at pH 6.5 are 45 and 100 days, respectively(6). Estimated soil hydrolysis half-lives in Wongan Hills loamy sand at 9, 20, and 28 °C were 144, 37, and 21 days, respectively(7). Humic and fulvic acids have been observed to favor the hydrolysis of triazine molecules(8). Microbial breakdown in soil results in degradation of simazine at very variable rates, half-lives range from 27 to 102 days (median 49 days); temperature and moisture are the main factors affecting the rates(5). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: TERRESTRIAL FATE: It has been reported that simazine and other s-triazines can be utilized by certain soil microorganisms as a source of energy(1). Microbial degradation products of simazine in soil include 2-chloro-4-amino-6-ethylamino-1,3,5-triazine and 2,4-dihydroxy-6-amino-1,3,5-triazine(1). Mineralization of 10.4% of (14)C-labeled simazine in 110 days has been reported in a clay-lime soil; no degradation of simazine was detected in a soil suspension test without the addition of glucose as an energy source suggesting that degradation of simazine in these soil experiments was due to co-metabolism(2). Reported persistence of simazine in soil varies from a half-life of <1 month(3) to no degradation being observed in 3.5 months(4). The amount of organic matter in the soil may have a significant effect on the persistence of simazine(3). Additions of 1%, 5%, and 10% leaf compost to soil gave simazine half-lives of about 140, 60, and 40 days, respectively(3). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: AQUATIC FATE: Based on a classification scheme(1), Koc values ranging from 78 to 3,559(2,3), indicate that some adsorption of simazine to suspended solids and sediment in the water column is expected(SRC). Increasing sorption has been observed with decreasing pH(14). Simazine is not expected to volatilize from water surfaces(4) based on an estimated Henry's Law constant of 9.4X10-10 atm-cu m/mole(SRC), derived from its vapor pressure, 2.2X10-8 mm Hg(5) and water solubility of 6.2 mg/L(5). According to a classification scheme(6), BCFs ranging from <1 to 55(7-9) suggest bioconcentration in aquatic organisms is low to moderate(SRC). Simazine is stable at pH 7 and 9 but the hydrolysis half-life at pH 5 and 25 °C is 70 days(10). The product of simazine hydrolysis is 2-hydroxy-4,6-bis(ethylamino)-1,3,5-triazine(10). Humic and fulvic acids have been observed to favor the hydrolysis of triazine molecules(11). Biodegradation in surface water samples from three ponds in Nagoya City, Japan, ranged from 0 to 30% after four days incubation; after 7 days incubation, biodegradation ranged from 0 to 24%(12). In Po River water, an initial simazine concentration of 5 ug/L was reduced to 3.1 and 2.5 Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: AQUATIC FATE: Dissipation of simazine in pond and lake water was variable, with half-lives ranging from 50 to 700 days. The degradation compound G-28279 /1,3,5-triazine-2,4-diamine, 6-chloro-N-ethyl-; CAS Number 1007-28-9/ was identified in lake water samples. Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: For more Environmental Fate (Complete) data for SIMAZINE (6 total), please visit the HSDB record page. Source: Hazardous Substances Data Bank (HSDB)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Records for CAS 122-34-9

1 total

How CAS 122-34-9 is used on this site

CAS 122-34-9 is the Chemical Abstracts Service identifier used to pin this page to a specific substance. In the current dataset, 1 EU annex record shares this identifier, which helps you cross-check whether the same substance appears under one regulatory context or several.

Use this page when a supplier specification, SDS or raw-material dossier gives you CAS 122-34-9 and you need to see every linked Annex II–VI record in one place. The entry cards above are the quickest route to concentration limits, warnings, annex placement and product-type conditions.

Frequently asked questions

A substance identified by CAS 122-34-9 may appear in multiple EU cosmetic regulation annexes when it is subject to different conditions in different contexts. For example, a substance might be restricted under Annex III with specific conditions, and the same CAS might also appear in Annex IV as an approved colorant under separate entry conditions. Each entry must be reviewed individually.

Cross-reference the CAS number against your raw material specification sheets and CoA documents. When a CAS appears in Annex II, verify absence. When it appears in Annex III, verify that concentration limits and product type conditions are met in your formulation. All annex entries sharing this CAS number are listed above.

A CAS number is assigned by the Chemical Abstracts Service (USA) and is globally recognised. An EC number is a European Commission identifier from inventories such as EINECS, ELINCS or the NLP list. Both identifiers may appear in EU cosmetic annex entries. Some substances have both, some have only one, and some older entries may have neither.

The INCI Checker accepts ingredient names, CAS numbers and EC numbers. Check this CAS number directly, then verify the result against supplier specification sheets and every linked annex condition.
Check this CAS number

Tools & next steps

Check your formula

Scan a full INCI list, then use CAS 122-34-9 to cross-check any supplier documents behind the matched substances.

INCI Checker

Browse annexes

Browse all EU cosmetic regulation annexes by category.

All annexes

Search by name

Search for INCI names, aliases or related identifiers that sit alongside CAS 122-34-9 in your documentation.

Search