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ProhibitedBinding ruleNZOriginal is EnglishOfficial-source import checked

Mesotrione (ISO) (2-[4-(methylsulfonyl)-2-nitrobenzoyl]-1,3-cyclohexanedione)

New Zealand Cosmetic Products Group Standard Schedule 4, reference 1677.

All New Zealand recordsCompare all marketsOpen official source

Regulatory decision and full conditions

Status
Prohibited
Legal role
Binding rule
Regulatory summary
New Zealand Cosmetic Products Group Standard Schedule 4, reference 1677.
Conditions and restrictions
A prohibition entry may contain no separate condition text because the regulatory outcome is the prohibition itself. Open the cited source and apply the market-wide requirements below.

Substance identity

Official source name
Mesotrione (ISO) (2-[4-(methylsulfonyl)-2-nitrobenzoyl]-1,3-cyclohexanedione)
CAS
104206-82-8
EC
Not supplied in this source row
Identity mapping
standalone:official_nz_schedule
Search this identity across the siteCAS 104206-82-8

Cross-market snapshot for this identity

Exact linked records currently present in this site. An absent market means no imported exact match, not permission to use the substance.

5 market datasets
PubChem 2D chemical structure for CAS 104206-82-8
CAS 104206-82-8PubChem CID 175967

Verified chemistry for CAS 104206-82-8

Mesotrione

IUPAC name
2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione
Molecular formula
C14H13NO7S
Molecular weight
339.32 g/mol
Exact mass
339.04127293 Da
Monoisotopic mass
339.04127293 Da
XLogP3
0.7
Topological polar surface area
140.0 Ų
Molecular complexity
627.0
Formal charge
0
Hydrogen-bond donors
0
Hydrogen-bond acceptors
7
Rotatable bonds
3
Heavy atoms
23
Covalent units
1

Names and synonyms reported to PubChem

CHEBI:3832148TR68G21T(2-nitro-4-(methylsullfonyl))benzoylcyclohexane-1,3-dione1,3-Cyclohexanedione, 2-[4-(methylsulfonyl)-2-nitrobenzoyl]-ZA 12962-[4-(methylsulfonyl)-2-nitrobenzoyl]-1,3-cyclohexanedione2-(4-mesyl-2-nitrobenzoyl)cyclohexane-1,3-dione2-[4-(methanesulfonyl)-2-nitrobenzoyl]cyclohexane-1,3-dione
16 more reported names
1,3-Cyclohexanedione, 2-(4-(methylsulfonyl)-2-nitrobenzoyl)-2-(4-(METHYLSULFONYL)-2-NITROBENZOYL)-1,3-CYCLOHEXANEDIONE2-(4-(methanesulfonyl)-2-nitrobenzoyl)cyclohexane-1,3-dioneRefChem:156682mesotrione (ISO); 2-(4-(methylsulfonyl)-2-nitrobenzoyl)-1,3-cyclohexanedione600-533-42-(4-(Methylsulfonyl)-2-nitrobenzoyl)cyclohexane-1,3-dioneMesotrione [ISO]C14H13NO7S2-(4-methylsulphonyl-2-nitrobenzoyl)-1,3-cyclohexanedione2-(2'-nitro-4'-methylsulfonylbenzoyl)cyclohexane-1,3-dioneCallisto herbicideTenacity2-[4-(methylsulfonyl)-2-nitrobenzoyl]cyclohexane-1,3-dioneUNII-48TR68G21THSDB 7250
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D pharmacophore features
11
3D rings
2
3D hydrophobes
0
3D acceptor features
7
3D donor features
0
3D anionic centres
2
3D cationic centres
0
3D conformers
10
Effective 3D rotors
4.8
Machine-readable structure identifiers
SMILES
CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]
InChI
InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3
InChIKey
KPUREKXXPHOJQT-UHFFFAOYSA-N

Evidence from additional scientific databases

EMBL-EBI ChEBI
Exact identifier matchCHEBI:38321

mesotrione

An aromatic ketone that is cyclohexa-1,3-dione in which one of the hydrogens at position 2 is substituted by a 4-(methanesulfonyl)-2-nitrobenzoyl group.

Formula
C14H13NO7S
Average mass
339.325 g/mol
Monoisotopic mass
339.04127 Da
Formal charge
0
  • β-triketone — is a (CHEBI:140323)
  • aromatic ketone — is a (CHEBI:76224)
  • sulfone — is a (CHEBI:35850)
  • C-nitro compound — is a (CHEBI:35716)
  • EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor — has role (CHEBI:38317)
  • herbicide — has role (CHEBI:24527)
  • environmental contaminant — has role (CHEBI:78298)
  • xenobiotic — has role (CHEBI:35703)
  • carotenoid biosynthesis inhibitor — has role (CHEBI:138208)
  • benzophenone — has functional parent (CHEBI:41308)
  • EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor — has role (CHEBI:38317)
  • herbicide — has role (CHEBI:24527)
  • environmental contaminant — has role (CHEBI:78298)
  • xenobiotic — has role (CHEBI:35703)
  • carotenoid biosynthesis inhibitor — has role (CHEBI:138208)
  • β-triketone — is a (CHEBI:140323)
  • aromatic ketone — is a (CHEBI:76224)
  • sulfone — is a (CHEBI:35850)
  • C-nitro compound — is a (CHEBI:35716)
Additional curated names
2-[4-(methanesulfonyl)-2-nitrobenzoyl]cyclohexane-1,3-dione2-(2'-nitro-4'-methylsulfonylbenzoyl)cyclohexane-1,3-dione2-[4-(methylsulfonyl)-2-nitrobenzoyl]-1,3-cyclohexanedione2-(4-methylsulphonyl-2-nitrobenzoyl)-1,3-cyclohexanedione(2-nitro-4-(methylsullfonyl))benzoylcyclohexane-1,3-dione
Cross-references from this source

Mapped by: Exact CAS cross-reference in the ChEBI compound record. Source updated: 2018-03-04. Retrieved: 2026-08-31. Open source record

NIH PubChem PUG-View
Exact identifier match175967

Attributed physical-property, hazard, environmental and use annotations.

  • Signal: Warning Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • GHS Hazard Statements: H361d: Suspected of damaging the unborn child [Warning Reproductive toxicity]; H373: May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]; H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]; H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Precautionary Statement Codes: P203, P260, P273, P280, P318, P319, P391, P405, and P501 (click each P-code to see the statement) Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Signal: Warning Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H361 (19.3%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]; H361d (46.2%): Suspected of damaging the unborn child [Warning Reproductive toxicity]; H373 (64.5%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]; H400 (100%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]; H410 (100%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P203, P260, P273, P280, P318, P319, P391, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 197 reports by companies from 13 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Signal: Warning Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
  • GHS Hazard Statements: H361d: Suspected of damaging the unborn child [Warning Reproductive toxicity]; H373: May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]; H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
  • Precautionary Statement Codes: P203, P260, P273, P280, P318, P319, P391, P405, and P501 (click each P-code to see the statement) Source: Hazardous Chemical Information System (HCIS), Safe Work Australia
  • Signal: Warning Source: Hazardous Substances Data Bank (HSDB)
  • GHS Hazard Statements: H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]; H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Source: Hazardous Substances Data Bank (HSDB)
  • Toxicity Summary: IDENTIFICATION AND USE: Mesotrione is a pale yellow solid with a faint pleasant odor. Mesotrione is an herbicide used on field corn, seed corn, sweet corn, yellow popcorn, and grain sorghum. Registered for use in the U.S. but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses. HUMAN EXPOSURE AND TOXICITY: Limited information is available on the effects of exposure to mesotrione on humans. Administration of mesotrione to volunteers resulted in an increase in plasma tyrosine concentrations, which reached a maximum of approximately 300 nmol/mL following a dose of 4 mg/kg body weight. Concentrations returned to background levels within 2 days of dosing. Urinary excretion of tyrosine metabolites was increased during the 24 hr immediately following a dose of 4 mg/kg, but returned to background levels during the following 24 hr period. Thus, the minimal and transient effects of mesotrione minimize the likelihood of a clinical effect in the event of systemic exposure occurring during occupational use. Mesotrione is not likely to be carcinogenic to humans. ANIMAL STUDIES: In animals, mesotrione is a mild Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Bioconcentration: An estimated BCF of 3 was calculated for mesotrione(SRC), using a measured log Kow range of 0.90 at pH 5 to <-1.0 at pH 9(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: TERRESTRIAL FATE: Based on a classification scheme(1), Koc values measured in 19 soils from the US and Europe ranging from 15 to 390(2,3), indicate that mesotrione is expected to have very high to moderate mobility in soil(SRC). Mesotrione is a weak acid with a pKa of 3.12(4) which indicates mesotrione will primarily exist in anion form in the environment and anions generally do not adsorb more strongly to organic carbon and clay than their neutral counterparts(5). The anionic form of mesotrione is a resonance enol-tautomer of the undissociated keto-tautomer(2). The Koc is inversely correlated with pH; as the pH increases, the Koc decreases(2,3). Volatilization of mesotrione from moist soil surfaces is not expected to be an important fate process(SRC) given an estimated Henry's Law constant of <1.2X10-10 atm-cu m/mole(SRC) derived from its vapor pressure, <4.27X10-8 mm Hg(6), and water solubility, 160 mg/L(6). Mesotrione is not expected to volatilize from dry soil surfaces(SRC) based upon its vapor pressure. The direct photolysis half-life on soil surfaces has been estimated to be 24 days at a latitude of 37-50 deg north(4). Degradation studies in active versus sterilized soils hav Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: AQUATIC FATE: Based on a classification scheme(1), Koc values measured in 19 soils from the US and Europe ranging from 15 to 390(2,3), indicate that mesotrione is not expected to adsorb to suspended solids and sediment(SRC). In water-sediment distribution tests, mesotrione was predominantly found in the water phase (>82%) with a maximum of 3.8% partitioning to sediment(4). Mesotrione is a weak acid with a pKa of 3.12(4) which indicates mesotrione will primarily exist in anion form in the environment and the anionic form of mesotrione is a resonance enol-tautomer of the undissociated keto-tautomer(2). Volatilization from water surfaces is not expected(5) based upon an estimated Henry's Law constant of <1.2X10-10 atm-cu m/mole(SRC), derived from its vapor pressure, <4.27X10-8 mm Hg(6), and water solubility, 160 mg/L(6). According to a classification scheme(7), an estimated BCF of 3(SRC), from its log Kow of 0.90 at pH 5(4) and a regression-derived equation(8), suggests the potential for bioconcentration in aquatic organisms is low. Mesotrione is stable to hydrolysis at pH 4-9(4). Mesotrione is susceptible to direct photolysis in water with estimated half-lives of 81-97 days under sum Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), mesotrione, which has a vapor pressure of <4.27X10-8 mm Hg at 20 °C(2), is expected to exist solely in the particulate phase in the ambient atmosphere. Particulate-phase mesotrione may be removed from the air by wet and dry deposition(SRC). Mesotrione absorbs at wavelengths >290 nm(3) and, therefore, may be susceptible to direct photolysis by sunlight(SRC). Source: Hazardous Substances Data Bank (HSDB)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
EMBL-EBI ChEBIExact match2026-08-31
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Official source and provenance

Registered source
New Zealand cosmetic product schedules 4–8
Source reference
Schedule 4, reference 1677, source row 2175
Source record ID
S4-2175
Source version
effective-2026-01-01
Source language
English
Translation status
Original is English
Effective date
2026-01-01
Source updated
2024-01-01
Snapshot checked
2026-08-30 04:54 UTC
Validation method
openpyxl extraction; reviewed per-schedule counts
SHA-256
4e62e372fb0aad7ac630af8c41fa50b38b52a793fd51b99697a65f8ecce1ae8a

Registered dataset notes

Dataset coverage
Prohibited and restricted substances, permitted colorants, preservatives and UV filters
Authority note
Official EPA group standard schedules; current market-specific rule source
Inspect the exact official sourceRegulator guidance

How this record fits the market dataset

2913
current New Zealand records
2166
records marked Prohibited
2913
records from this source version
2821
market records with CAS identity

Status distribution

Permitted list with conditions: 357Prohibited: 2166Restricted: 390

Condition text is present on 747 of 2913 current records. An empty condition field is interpreted according to the record type above; it is never converted into an unrestricted-use claim.

New Zealand market context

Complete schedules dataset

Coverage version: Cosmetic Products Group Standard schedules effective 1 January 2026

Schedules 4–8: prohibited, restricted, colourant, preservative and UV-filter entries.

Verification checklist

  1. Search exact identity across Schedules 4–8.
  2. Apply use, concentration and warning conditions.
  3. Check hazardous-substance classification and Group Standard scope.
  4. Confirm the latest legal instrument, not only the spreadsheet.

Official market sources

Verification workflow and record completeness

Before using this result in a compliance decision

  1. Confirm that “Mesotrione (ISO) (2-[4-(methylsulfonyl)-2-nitrobenzoyl]-1,3-cyclohexanedione)” and every CAS/EC identifier refer to the material in your supplier specification.
  2. Search exact identity across Schedules 4–8.
  3. Apply use, concentration and warning conditions.
  4. Check hazardous-substance classification and Group Standard scope.
  5. Confirm the latest legal instrument, not only the spreadsheet.
  6. Document the source version and recheck the regulator before manufacture, notification or market placement.

Fields available in this record

  • Official substance nameAvailable
  • CASAvailable
  • ECNot supplied
  • Separate condition textNot present in source row
  • Effective dateAvailable
  • Snapshot hash and methodAvailable

Questions this page answers

This official record identifies the substance as prohibited for cosmetic use in the stated market scope. Do not rely on a formulation containing this identity until the cited source, effective date and exact substance match have been verified.

A prohibition entry may contain no separate condition text because the regulatory outcome is the prohibition itself. The searchable spreadsheet is an aid; the legal Group Standard and incorporated notices remain authoritative.

The record cites Schedule 4, reference 1677, source row 2175, source version effective-2026-01-01. Open the official source.

No. CAS helps resolve identity, but jurisdictions can classify the same substance differently and can apply different product scopes, limits, warnings and transition dates.

Stable citation

Mesotrione (ISO) (2-[4-(methylsulfonyl)-2-nitrobenzoyl]-1,3-cyclohexanedione). Schedule 4, reference 1677, source row 2175. New Zealand. Source version effective-2026-01-01. CosIng Checker regulatory record: https://cosingchecker.com/regulations/nz/records/8833/

Cite the regulator as the legal authority. This page is a structured evidence index and verification aid, not a substitute for the official text or professional legal assessment.

Interpretation and limits for New Zealand

This official record identifies the substance as prohibited for cosmetic use in the stated market scope.

Do not rely on a formulation containing this identity until the cited source, effective date and exact substance match have been verified.

How to interpret the legal role

The cited row forms part of a binding rule or legally incorporated list for this market.

Evidence on this page

  • Recorded outcome: Prohibited
  • Legal role: Binding rule
  • Source version: effective-2026-01-01
  • Effective date: 2026-01-01

What it does not prove

The searchable spreadsheet is an aid; the legal Group Standard and incorporated notices remain authoritative.

Further authoritative substance research

These sources can add identity, safety, exposure or hazard context. A link is not evidence that the database contains this exact substance, and none of these sources overrides the market decision above.

Cosmetic Ingredient Review safety assessments

Expert Panel conclusions, assessed ingredient groups, use conditions, dates and report documents

Independent expert review considered by FDA; not a government approval or binding market rule

Research this identity at the source

FDA Global Substance Registration System

UNII identifiers, preferred names, substance types, codes and public substance relationships

Identity registry only; UNII availability does not imply FDA review or approval

Research this identity at the source

ILO/WHO International Chemical Safety Cards

Hazards, symptoms, first aid, storage, incompatibilities and physical properties for covered chemicals

International occupational chemical-safety reference; not cosmetic-use approval

Research this identity at the source

Japan NITE-CHRIP

Chemical identity, Japanese and foreign legal lists, GHS hazards and exposure-related information

Chemical-management evidence; cosmetic status remains governed by the applicable MHLW standard and market rules

Research this identity at the source

NIOSH Pocket Guide to Chemical Hazards

REL, PEL, IDLH, properties, exposure routes, symptoms, target organs, first aid and measurement methods for covered workplace chemicals

US occupational-health guidance and limits; not a cosmetic ingredient decision

Research this identity at the source

OECD eChemPortal

Gateway to authority-owned physical-property, fate, ecotoxicity, toxicity, exposure and GHS records

Discovery gateway; each linked authority remains responsible for its data

Research this identity at the source

US EPA CompTox CTX APIs

API key required for import

DTXSID identity, experimental and predicted properties, toxicity, bioactivity, exposure and environmental data

Scientific and computational evidence; predictions must remain labelled and do not determine cosmetic legality

Research this identity at the source