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ProhibitedBinding ruleKRNo English translationOfficial-source import checked

바륨염(바륨설페이트 및 색소레이크희석제로 사용한 바륨염은 제외)

Listed by the Korean MFDS as a substance that may not be used in cosmetics.

All South Korea recordsOpen ingredient profileCompare all marketsOpen official source

Regulatory decision and full conditions

Status
Prohibited
Legal role
Binding rule
Regulatory summary
Listed by the Korean MFDS as a substance that may not be used in cosmetics.
Conditions and restrictions
바륨클로라이드바륨글루코네이트

Substance identity

Official source name
바륨염(바륨설페이트 및 색소레이크희석제로 사용한 바륨염은 제외)
CAS
10361-37-2; 22561-74-6
EC
233-788-1
Identity mapping
cas_number
Linked ingredient
BARIUM CHLORIDE
Search this identity across the siteCAS 10361-37-2CAS 22561-74-6EC 233-788-1

Linked CosIng identity data

Names and aliases

BARIUM CHLORIDE

EU inventory restriction note: II/46

Recorded cosmetic function: NOT REPORTED

Function pages:NOT REPORTED

View the complete ingredient profile

Cross-market snapshot for this identity

Exact linked records currently present in this site. An absent market means no imported exact match, not permission to use the substance.

2 market datasets
PubChem 2D chemical structure for CAS 10361-37-2
CAS 10361-37-2PubChem CID 25204

Verified chemistry for CAS 10361-37-2

Barium chloride

IUPAC name
barium(2+) dichloride
Molecular formula
BaCl2
Molecular weight
208.23 g/mol
Exact mass
207.842952 Da
Monoisotopic mass
207.842952 Da
Topological polar surface area
0.0 Ų
Molecular complexity
2.0
Formal charge
0
Hydrogen-bond donors
0
Hydrogen-bond acceptors
2
Rotatable bonds
0
Heavy atoms
3
Covalent units
3

Names and synonyms reported to PubChem

Barium chloride (BaCl2)Ba 0108ESBA 0108ENCI-C610740VK51DA1T2NSC-146181DICHLOROBARIUMRefChem:5582
16 more reported names
233-788-1BaCl2Barium dichlorideCHEBI:63317Barium chloride, 99.9% trace metals basisBarium chloride, anhydrousBarium chloride, ultra dryBariumchloridCCRIS 2286HSDB 2633Barium Chloride Dihydrate (8CI); Barium Chloride (BaCl2) Hydrate; Barium Dichloride DihydrateEINECS 233-788-1NSC 146181UNII-0VK51DA1T2WLN: BA G2Ba-0108E
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
[Cl-].[Cl-].[Ba+2]
InChI
InChI=1S/Ba.2ClH/h;2*1H/q+2;;/p-2
InChIKey
WDIHJSXYQDMJHN-UHFFFAOYSA-L

Evidence from additional scientific databases

EMBL-EBI ChEBI
Exact identifier matchCHEBI:63317

barium chloride

The inorganic dichloride salt of barium.

Formula
Ba.2Cl
Average mass
208.234 g/mol
Monoisotopic mass
207.84295 Da
Formal charge
0
  • inorganic chloride — is a (CHEBI:36093)
  • barium salt — is a (CHEBI:63320)
  • potassium channel blocker — has role (CHEBI:50509)
  • NMR chemical shift reference compound — has role (CHEBI:228364)
  • potassium channel blocker — has role (CHEBI:50509)
  • NMR chemical shift reference compound — has role (CHEBI:228364)
  • inorganic chloride — is a (CHEBI:36093)
  • barium salt — is a (CHEBI:63320)
Additional curated names
barium dichlorideBaCl2
Cross-references from this source
  • CAS: 10361-37-2 — ChemIDplus
  • CAS: 10361-37-2 — NIST Chemistry WebBook
  • REGISTRY_NUMBER: 1209229 — Reaxys
  • REGISTRY_NUMBER: 8128158 — Reaxys
  • MANUAL_X_REF: Barium_chloride — Wikipedia
  • MANUAL_X_REF: CPD0-1592 — MetaCyc

Mapped by: Exact CAS cross-reference in the ChEBI compound record. Source updated: 2024-06-06. Retrieved: 2026-08-31. Open source record

NIH PubChem PUG-View
Exact identifier match25204

Attributed physical-property, hazard, environmental and use annotations.

  • First Aid: EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.; SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.; INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Ap Source: CAMEO Chemicals
  • First Aid: (General first aid procedures); Eye: Irrigate immediately - If this chemical contacts the eyes, immediately wash (irrigate) the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately.; Skin: Water flush immediately - If this chemical contacts the skin, immediately flush the contaminated skin with water. If this chemical penetrates the clothing, immediately remove the clothing and flush the skin with water. Get medical attention promptly.; Breathing: Respiratory support; Swallow: Medical attention immediately - If this chemical has been swallowed, get medical attention immediately. Source: The National Institute for Occupational Safety and Health (NIOSH)
  • Signal: Danger Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • GHS Hazard Statements: H301: Toxic if swallowed [Danger Acute toxicity, oral]; H332: Harmful if inhaled [Warning Acute toxicity, inhalation] Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Precautionary Statement Codes: P261, P264, P270, P271, P301+P316, P304+P340, P317, P321, P330, P405, and P501 (click each P-code to see the statement) Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Note: This chemical does not meet GHS hazard criteria for 0.3% (3 of 881) of reports. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H301 (99.5%): Toxic if swallowed [Danger Acute toxicity, oral]; H319 (75%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H332 (99.7%): Harmful if inhaled [Warning Acute toxicity, inhalation]; H413 (14.2%): May cause long lasting harmful effects to aquatic life [Hazardous to the aquatic environment, long-term hazard] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P261, P264, P264+P265, P270, P271, P273, P280, P301+P316, P304+P340, P305+P351+P338, P317, P321, P330, P337+P317, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 881 reports by companies from 11 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 3 of 881 reports by companies.; There are 10 notifications provided by 878 of 881 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: NITE-CMC
  • GHS Hazard Statements: H301: Toxic if swallowed [Danger Acute toxicity, oral]; H315: Causes skin irritation [Warning Skin corrosion/irritation]; H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]; H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]; H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]; H402: Harmful to aquatic life [Hazardous to the aquatic environment, acute hazard]; H412: Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] Source: NITE-CMC
  • Precautionary Statement Codes: P260, P261, P264, P264+P265, P270, P271, P273, P280, P301+P316, P302+P352, P304+P340, P305+P351+P338, P308+P316, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
  • GHS Hazard Statements: H301: Toxic if swallowed [Danger Acute toxicity, oral]; H315: Causes skin irritation [Warning Skin corrosion/irritation]; H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]; H336: May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure; Narcotic effects]; H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]; H371: May cause damage to organs [Warning Specific target organ toxicity, single exposure]; H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]; H373: May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure] Source: NITE-CMC
  • Health Effects: The health effects of the different barium compounds depend on how well the compound dissolves in water or the stomach contents. At low doses, barium acts as a muscle stimulant, while higher doses affect the nervous system, causing cardiac irregularities, tremors, weakness, anxiety, dyspnea, paralysisand possibly death. Barium may also cause gastrointestinal disturbances, damage the kidneys and cause decreases in body weight. (L214) Source: Toxin and Toxin Target Database (T3DB)
  • Toxicity Summary: Barium is a competitive potassium channel antagonist that blocks the passive efflux of intracellular potassium, resulting in a shift of potassium from extracellular to intracellular compartments. The intracellular translocation of potassium results in a decreased resting membrane potential, making the muscle fibers electrically unexcitable and causing paralysis. Some of these barium's effects may also be due to barium induced neuromuscular blockade and membrane depolarization. (L214) Source: Toxin and Toxin Target Database (T3DB)
  • Sources/Uses: Used to manufacture pigments, color lakes, glass, and mordant for acid dyes; for weighting and dyeing textile fabrics; in aluminum refining; as pesticide; as boiler compound for softening water; for tanning and finishing leather; in treating wool for stuffing mattresses; in lubrication oil additives; as an intermediate for barium salts; as intermediate for steel hardening compounds; in the production of magnesium metal; in chemical analysis; as 5% constituent of material (ternary eutectic salt) effective in extinguishing fires of uranium and plutonium; [HSDB] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Industrial Processes with risk of exposure: Aluminum Producing [Category: Industry]; Steel Producing [Category: Industry]; Metal Preparation and Pouring [Category: Foundry]; Textiles (Fiber & Fabric Manufacturing) [Category: Industry]; Leather Tanning and Processing [Category: Industry]; Glass Manufacturing [Category: Industry] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Uses: Manufacture pigments, color lakes, glass, mordant for acid dyes; weighting and dyeing textile fabrics; in aluminum refining; as pesticide; boiler cmpd for softening water; tanning and finishing leather. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Used in treating wool for stuffing mattresses. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Chemicals (artificial barium sulfate, other barium salts); reagents, lubrication oil additives; boiler compounds, textile dying, pigments, manufacture of white leather. /Barium chloride dihydrate/ Source: Hazardous Substances Data Bank (HSDB)
  • Uses: For chlorine and sodium hydroxide manufacture, as flux for magnesium alloys. /Barium chloride, dihydrate/ Source: Hazardous Substances Data Bank (HSDB)
  • Uses: For more Uses (Complete) data for Barium chloride (7 total), please visit the HSDB record page. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Barium chloride is used in the laboratory as a test for sulfate ion. In industry, barium chloride is mainly used in the purification of brine solution in caustic chlorine plants and also in the manufacture of heat treatment salts, case hardening of steel, in the manufacture of pigments, and in the manufacture of other barium salts. It is also used in fireworks to give a bright green color. (L204) Source: Toxin and Toxin Target Database (T3DB)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
EMBL-EBI ChEBIExact match2026-08-31
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 22561-74-6
CAS 22561-74-6PubChem CID 89753

Verified chemistry for CAS 22561-74-6

Barium gluconate

IUPAC name
barium(2+);bis((2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate)
Molecular formula
C12H22BaO14
Molecular weight
527.62 g/mol
Exact mass
528.006202 Da
Monoisotopic mass
528.006202 Da
Topological polar surface area
283.0 Ų
Molecular complexity
165.0
Formal charge
0
Hydrogen-bond donors
10
Hydrogen-bond acceptors
14
Rotatable bonds
8
Heavy atoms
27
Covalent units
3

Names and synonyms reported to PubChem

D-Gluconic acid, barium saltBarium di-D-gluconateEINECS 245-081-5NSC-1945Barium di(D-gluconate)UNII-C23395US5PTox21_110002CAS-5328-41-6
2 more reported names
D-GLUCONIC ACID, BARIUM SALT (2:1)GLUCONIC ACID, BARIUM SALT (2:1), D-
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
8
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
C([C@H]([C@H]([C@@H]([C@H](C(=O)[O-])O)O)O)O)O.C([C@H]([C@H]([C@@H]([C@H](C(=O)[O-])O)O)O)O)O.[Ba+2]
InChI
InChI=1S/2C6H12O7.Ba/c2*7-1-2(8)3(9)4(10)5(11)6(12)13;/h2*2-5,7-11H,1H2,(H,12,13);/q;;+2/p-2/t2*2-,3-,4+,5-;/m11./s1
InChIKey
PECPTSUHUFWKDG-IYEMJOQQSA-L

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Official source and provenance

Registered source
South Korea MFDS cosmetic ingredient data
Source reference
화장품 안전기준 등에 관한 규정, 별표 1, record 1-378
Source record ID
1-378
Source version
2026-19
Source language
Korean
Translation status
No English translation
Effective date
2026-03-18
Source updated
2026-03-18
Snapshot checked
2026-08-30 04:33 UTC
Validation method
MFDS JSON appendices 1–2 parse; 1077 prohibited, 243 restricted
SHA-256
056de35b843a5e31f709073f9e79d5e6e18f7c9164eb537bb099b185a37ef7d8

Registered dataset notes

Dataset coverage
Ingredient identity and separate restriction/regulation data endpoints
Authority note
Korean source is canonical; English materials alone are not complete enough for certification
Inspect the exact official sourceRegulator guidance

How this record fits the market dataset

1320
current South Korea records
1077
records marked Prohibited
1320
records from this source version
1252
market records with CAS identity

Status distribution

Prohibited: 1077Restricted: 243

Condition text is present on 638 of 1320 current records. An empty condition field is interpreted according to the record type above; it is never converted into an unrestricted-use claim.

South Korea market context

Complete current appendix dataset

Coverage version: MFDS Notice 2026-19, effective 18 March 2026

All rows in official Appendix 1 (prohibited) and Appendix 2 (restricted) of the Safety Standards for Cosmetics.

Verification checklist

  1. Match the Korean canonical substance name and identifiers.
  2. Review all Appendix 1 and 2 matches and conditions.
  3. Check functional-cosmetic and positive-list requirements where applicable.
  4. Confirm current MFDS notice, responsible seller and label obligations.

Official market sources

Verification workflow and record completeness

Before using this result in a compliance decision

  1. Confirm that “바륨염(바륨설페이트 및 색소레이크희석제로 사용한 바륨염은 제외)” and every CAS/EC identifier refer to the material in your supplier specification.
  2. Match the Korean canonical substance name and identifiers.
  3. Review all Appendix 1 and 2 matches and conditions.
  4. Check functional-cosmetic and positive-list requirements where applicable.
  5. Confirm current MFDS notice, responsible seller and label obligations.
  6. Document the source version and recheck the regulator before manufacture, notification or market placement.

Fields available in this record

  • Official substance nameAvailable
  • CASAvailable
  • ECAvailable
  • Separate condition textAvailable
  • Effective dateAvailable
  • Snapshot hash and methodAvailable

Questions this page answers

This official record identifies the substance as prohibited for cosmetic use in the stated market scope. Do not rely on a formulation containing this identity until the cited source, effective date and exact substance match have been verified.

A prohibition entry may contain no separate condition text because the regulatory outcome is the prohibition itself. Korean source wording is canonical and other positive lists/notices may still apply to the formulation.

The record cites 화장품 안전기준 등에 관한 규정, 별표 1, record 1-378, source version 2026-19. Open the official source.

No. CAS helps resolve identity, but jurisdictions can classify the same substance differently and can apply different product scopes, limits, warnings and transition dates.

Stable citation

바륨염(바륨설페이트 및 색소레이크희석제로 사용한 바륨염은 제외). 화장품 안전기준 등에 관한 규정, 별표 1, record 1-378. South Korea. Source version 2026-19. CosIng Checker regulatory record: https://cosingchecker.com/regulations/kr/records/1137/

Cite the regulator as the legal authority. This page is a structured evidence index and verification aid, not a substitute for the official text or professional legal assessment.

Interpretation and limits for South Korea

This official record identifies the substance as prohibited for cosmetic use in the stated market scope.

Do not rely on a formulation containing this identity until the cited source, effective date and exact substance match have been verified.

How to interpret the legal role

The cited row forms part of a binding rule or legally incorporated list for this market.

Evidence on this page

  • Recorded outcome: Prohibited
  • Legal role: Binding rule
  • Source version: 2026-19
  • Effective date: 2026-03-18

What it does not prove

Korean source wording is canonical and other positive lists/notices may still apply to the formulation.

Further authoritative substance research

These sources can add identity, safety, exposure or hazard context. A link is not evidence that the database contains this exact substance, and none of these sources overrides the market decision above.

Cosmetic Ingredient Review safety assessments

Expert Panel conclusions, assessed ingredient groups, use conditions, dates and report documents

Independent expert review considered by FDA; not a government approval or binding market rule

Research this identity at the source

FDA Global Substance Registration System

UNII identifiers, preferred names, substance types, codes and public substance relationships

Identity registry only; UNII availability does not imply FDA review or approval

Research this identity at the source

ILO/WHO International Chemical Safety Cards

Hazards, symptoms, first aid, storage, incompatibilities and physical properties for covered chemicals

International occupational chemical-safety reference; not cosmetic-use approval

Research this identity at the source

Japan NITE-CHRIP

Chemical identity, Japanese and foreign legal lists, GHS hazards and exposure-related information

Chemical-management evidence; cosmetic status remains governed by the applicable MHLW standard and market rules

Research this identity at the source

NIOSH Pocket Guide to Chemical Hazards

REL, PEL, IDLH, properties, exposure routes, symptoms, target organs, first aid and measurement methods for covered workplace chemicals

US occupational-health guidance and limits; not a cosmetic ingredient decision

Research this identity at the source

OECD eChemPortal

Gateway to authority-owned physical-property, fate, ecotoxicity, toxicity, exposure and GHS records

Discovery gateway; each linked authority remains responsible for its data

Research this identity at the source

US EPA CompTox CTX APIs

API key required for import

DTXSID identity, experimental and predicted properties, toxicity, bioactivity, exposure and environmental data

Scientific and computational evidence; predictions must remain labelled and do not determine cosmetic legality

Research this identity at the source