Cadmium nitrate; cadmium dinitrate (CAS No. 10325-94-7)
IS 4707 Part 2:2025 Annex A lists this ingredient as one that must not form part of a cosmetic product in India.
Regulatory decision and full conditions
- Status
- Prohibited
- Legal role
- Binding rule
- Regulatory summary
- IS 4707 Part 2:2025 Annex A lists this ingredient as one that must not form part of a cosmetic product in India.
- Conditions and restrictions
- Must not form part of the composition of cosmetic products. Apply the general trace and safety notes published after Annex A.
Substance identity
- Official source name
- Cadmium nitrate; cadmium dinitrate (CAS No. 10325-94-7)
- CAS
- 10325-94-7
- EC
- Not supplied in this source row
- Identity mapping
- standalone:official_bis_record
Cross-market snapshot for this identity
Exact linked records currently present in this site. An absent market means no imported exact match, not permission to use the substance.
European Union
1 linked record
Open supporting recordGreat Britain
1 linked record
Open supporting recordNew Zealand
1 linked record
Open supporting recordASEAN
1 linked record
Open supporting recordIndia
Current record1 linked record · 1 with specific conditions
Open supporting recordSaudi Arabia
1 linked record
Open supporting recordVerified chemistry for CAS 10325-94-7
Cadmium Nitrate
- IUPAC name
- cadmium(2+) dinitrate
- Molecular formula
- CdN2O6
- Molecular weight
- 236.42 g/mol
- Exact mass
- 237.879001 Da
- Monoisotopic mass
- 237.879001 Da
- Topological polar surface area
- 126.0 Ų
- Molecular complexity
- 18.0
- Formal charge
- 0
- Hydrogen-bond donors
- 0
- Hydrogen-bond acceptors
- 6
- Rotatable bonds
- 0
- Heavy atoms
- 9
- Covalent units
- 3
Names and synonyms reported to PubChem
14 more reported names
External database identifiers
- ChEBI:CHEBI:77732
Advanced structure statistics
- Defined atom stereocentres
- 0
- Undefined atom stereocentres
- 0
- Defined bond stereocentres
- 0
- Undefined bond stereocentres
- 0
- 3D conformers
- 0
Machine-readable structure identifiers
- SMILES
[N+](=O)([O-])[O-].[N+](=O)([O-])[O-].[Cd+2]- InChI
InChI=1S/Cd.2NO3/c;2*2-1(3)4/q+2;2*-1- InChIKey
XIEPJMXMMWZAAV-UHFFFAOYSA-N
Evidence from additional scientific databases
EMBL-EBI ChEBI
cadmium nitrate
An inorganic nitrate salt having Cd(2+) as the counterion.
- Formula
- Cd.2NO3
- Average mass
- 236.420 g/mol
- Monoisotopic mass
- 237.87899 Da
- Formal charge
- 0
- cadmium salt — is a (CHEBI:50293)
- inorganic nitrate salt — is a (CHEBI:51084)
- carcinogenic agent — has role (CHEBI:50903)
- hepatotoxic agent — has role (CHEBI:50908)
- genotoxin — has role (CHEBI:50902)
- cadmium(2+) — has part (CHEBI:48775)
- carcinogenic agent — has role (CHEBI:50903)
- hepatotoxic agent — has role (CHEBI:50908)
- genotoxin — has role (CHEBI:50902)
- cadmium salt — is a (CHEBI:50293)
- inorganic nitrate salt — is a (CHEBI:51084)
Additional curated names
Cross-references from this source
- CAS: 10325-94-7 — ChemIDplus
- REGISTRY_NUMBER: 8156730 — Reaxys
- MANUAL_X_REF: Cadmium_nitrate — Wikipedia
Mapped by: Exact CAS cross-reference in the ChEBI compound record. Source updated: 2015-06-24. Retrieved: 2026-08-31. Open source record
NIH PubChem PUG-View
Attributed physical-property, hazard, environmental and use annotations.
- Boiling Point: 132 °C @760 [mm Hg] Source: PAC Chemical Database, U.S. Department of Energy
- Color/Form: White cubic crystals Source: Hazardous Substances Data Bank (HSDB)
- Color/Form: White, amorphous pieces or hygroscopic needles Source: Hazardous Substances Data Bank (HSDB)
- Color/Form: White, prismatic needles Source: Hazardous Substances Data Bank (HSDB)
- Density: 2.45 at 68 °F (USCG, 1999) - Denser than water; will sink Source: CAMEO Chemicals
- Density: 3.6 g/cu cm Source: Hazardous Substances Data Bank (HSDB)
- Density: 3.6 @25 °C Source: PAC Chemical Database, U.S. Department of Energy
- Melting Point: 138 °F (USCG, 1999) Source: CAMEO Chemicals
- Melting Point: 360 °C Source: Hazardous Substances Data Bank (HSDB)
- Melting Point: 360 °C Source: PAC Chemical Database, U.S. Department of Energy
- Physical Description: Cadmium nitrate is an odorless white solid. Sinks in water. (USCG, 1999) Source: CAMEO Chemicals
- Physical Description: White solid; [HSDB] White odorless crystals; [MSDSonline] There are 3 hydrates that form at temperatures <56 deg C; [Ullmann] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Solubility: Soluble in ammonia, alcohol Source: Hazardous Substances Data Bank (HSDB)
- Solubility: Sol in ethanol Source: Hazardous Substances Data Bank (HSDB)
- Solubility: Soluble in ether, acetone Source: Hazardous Substances Data Bank (HSDB)
- Solubility: In water, 156 g/100 g water at 25 °C Source: Hazardous Substances Data Bank (HSDB)
- Carcinogen Classification: 1, carcinogenic to humans. (L135) Source: Toxin and Toxin Target Database (T3DB)
- Exposure Routes: Oral (L6) ; inhalation (L6) ; dermal (L6) Source: Toxin and Toxin Target Database (T3DB)
- First Aid: INHALATION: remove patient to fresh air; seek medical attention.; INGESTION: give large amounts of water and induce vomiting; give milk or egg whites; seek medical attention.; EYES: flush with copious amounts of water for 15 min.; consult a physician.; SKIN: wash with soap and water. (USCG, 1999) Source: CAMEO Chemicals
- Signal: Danger Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
- GHS Hazard Statements: H302: Harmful if swallowed [Warning Acute toxicity, oral]; H312: Harmful in contact with skin [Warning Acute toxicity, dermal]; H332: Harmful if inhaled [Warning Acute toxicity, inhalation]; H340: May cause genetic defects [Danger Germ cell mutagenicity]; H350: May cause cancer [Danger Carcinogenicity]; H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]; H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]; H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
- Precautionary Statement Codes: P203, P260, P261, P264, P270, P271, P273, P280, P301+P317, P302+P352, P304+P340, P317, P318, P319, P321, P330, P362+P364, P391, P405, and P501 (click each P-code to see the statement) Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
- Signal: Danger Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H301 (90%): Toxic if swallowed [Danger Acute toxicity, oral]; H302+H312+H332 (31.4%): Harmful if swallowed, in contact with skin or if inhaled [Warning Acute toxicity, oral; acute toxicity, dermal; acute toxicity, inhalation]; H302 (10%): Harmful if swallowed [Warning Acute toxicity, oral]; H312 (42.9%): Harmful in contact with skin [Warning Acute toxicity, dermal]; H330 (90%): Fatal if inhaled [Danger Acute toxicity, inhalation]; H332 (10%): Harmful if inhaled [Warning Acute toxicity, inhalation]; H340 (90%): May cause genetic defects [Danger Germ cell mutagenicity]; H350 (92.9%): May cause cancer [Danger Carcinogenicity]; H360 (88.6%): May damage fertility or the unborn child [Danger Reproductive toxicity]; H372 (90%): Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]; H400 (100%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]; H410 (100%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P203, P260, P261, P264, P270, P271, P273, P280, P284, P301+P316, P301+P317, P302+P352, P304+P340, P316, P317, P318, P319, P320, P321, P330, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 70 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- Signal: Danger Source: NITE-CMC
- GHS Hazard Statements: H340: May cause genetic defects [Danger Germ cell mutagenicity] Source: NITE-CMC
- Precautionary Statement Codes: P203, P280, P318, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
- GHS Hazard Statements: H301: Toxic if swallowed [Danger Acute toxicity, oral]; H341: Suspected of causing genetic defects [Warning Germ cell mutagenicity]; H350: May cause cancer [Danger Carcinogenicity]; H361: Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]; H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]; H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure] Source: NITE-CMC
- Precautionary Statement Codes: P203, P260, P264, P270, P280, P301+P316, P308+P316, P318, P319, P321, P330, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
- Health Effects: Chronic exposure to cadmium fumes can cause chemical pneumonitis, pulmonary edema, and lung diseases such as bronchitis and emphysema. Cadmium also accumulates in the kidneys, causing permanent damage. Loss of bone density also occurs. Nitrate and nitrite poisoning causes methemoglobinemia. Nitrites may cause pregnancy complications and developmental effects. They may also be carcinogenic. (L1137, L6) Source: Toxin and Toxin Target Database (T3DB)
- Toxicity Summary: Cadmium initially binds to metallothionein and is transported to the kidney. Toxic effects are observed once the concentration of cadmium exceeds that of available metallothionein, and it has also been shown that the cadmium-metallothionein complex may be damaging. Accumulation of cadmium in the kidney results in increased excretion of vital low and high weight molecular proteins. Cadmium is a high affinity zinc analog and can interfere in its biological processes. It also binds to and activates the estrogen receptor, likely stimulating the growth of certain types of cancer cells and causing other estrogenic effects, such as reproductive dysfunction. Cadmium causes cell apoptosis by activating mitogen-activated protein kinases. Nitrate's toxicity is a result of it's conversion to nitrite once in the body. Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and methemoglobin. This elevation of methemoglobin levels is a condition known as methemoglobinemia, and is characterized by tissue hypoxia, as methemoglobin cannot bind oxygen. (A2450, L1613, L8, A18, A19, A28) Source: Toxin and Toxin Target Database (T3DB)
- Environmental Bioconcentration: Salvinia natans (fern) exposed to cadmium nitrate for 21 days exhibited a bioconcentration factor of 960. Source: Hazardous Substances Data Bank (HSDB)
- Environmental Bioconcentration: Mya arenaria, (soft shell clam) exposed to cadmium nitrate for 70 days exhibited a bioconcentration factor of 160. Source: Hazardous Substances Data Bank (HSDB)
- Environmental Bioconcentration: Crassostrea virginica, (American oyster) exposed to cadmium nitrate for 98 days exhibited a bioconcentration factor of 1,220. Source: Hazardous Substances Data Bank (HSDB)
- Environmental Bioconcentration: Lemna valdiviana (duck weed) exposed to cadmium nitrate for 21 days exhibited a bioconcentration factor of 603. Source: Hazardous Substances Data Bank (HSDB)
- Sources/Uses: Used in photographic emulsions, nuclear reactors to control rate of nuclear fission, and glass and ceramic colorants; [HSDB] Used in storage batteries and to make red lusters in glass and porcelain; [Ullmann] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Industrial Processes with risk of exposure: Battery Manufacturing [Category: Industry]; Photographic Processing [Category: Other]; Glass Manufacturing [Category: Industry] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Activities with risk of exposure: Ceramics making [Category: Hobbies] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Uses: In making other cadmium salts; in photographic emulsions. Source: Hazardous Substances Data Bank (HSDB)
- Uses: Oxidation of the sulfide or sulfite under carefully controlled oxidizing atmospheres at high temperature. An alternate method involves treatment of powdered cadmium nitrate, halide, oxide, or carbonate with dimethyl sulfate. Source: Hazardous Substances Data Bank (HSDB)
- Uses: The use of cadmium soaps as components of PVC stabilizers is decreasing because of their toxic properties. Solid PVC stabilizers contain cadmium soaps of saturated fatty acids, whereas liquid stabilizers contain soaps of unsaturated or branched, short-chain fatty acids. The soaps act as heat and light stabilizers, and soaps of saturated fatty acids are used as lubricants in the processing of PVC. Unlike other metallic soaps used in the PVC sector, cadmium soaps do not affect transparency and are suitable for hard, transparent PVC products. However, for safety reason their use is nowadays being replaced by mixtures of calcium-zinc stearate plus other stabilizers. /Cadmium metallic soaps/ Source: Hazardous Substances Data Bank (HSDB)
- Uses: Production of red lusters in glass and porcelain and in cadmium-nickel sinter plates of storage batteries. Source: Hazardous Substances Data Bank (HSDB)
- Uses: For more Uses (Complete) data for CADMIUM NITRATE (6 total), please visit the HSDB record page. Source: Hazardous Substances Data Bank (HSDB)
- Uses: Cadmium nitrate is used mainly to prepare other cadmium salts. It is also used for coloring glass and porcelain and as a flash powder in photography. (L450) Source: Toxin and Toxin Target Database (T3DB)
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| EMBL-EBI ChEBI | Exact match | 2026-08-31 |
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Official source and provenance
- Registered source
- India BIS IS 4707 cosmetic ingredient standards
- Source reference
- IS 4707 (Part 2):2025 Annex A, entry 1603
- Source record ID
annex-a:1603- Source version
- IS 4707 (Part 2):2025, fifth revision
- Source language
- English
- Translation status
- Original is English
- Effective date
- 2025-08-09
- Source updated
- 2025-08-09
- Snapshot checked
- 2026-08-31 15:30 UTC
- Validation method
- 206 text layers; Annex A 1-1614 and Annex B 1-313 with seven lettered source rows
- SHA-256
905dd0326361c53da8a354b948331946951ac3ae27d60d8e2474efb051239603
Registered dataset notes
- Dataset coverage
- Complete current Part 2:2025 Annex A prohibited and Annex B restricted rows; Parts 1, 3 and 4 remain linked official checks
- Authority note
- Indian Standards referenced by the cosmetics regulatory framework; use the controlled current editions
How this record fits the market dataset
Status distribution
Condition text is present on 1931 of 1931 current records. An empty condition field is interpreted according to the record type above; it is never converted into an unrestricted-use claim.
India market context
Complete current Part 2 dataset plus official workflow for Parts 1, 3 and 4
Coverage version: Cosmetics Rules 2020 plus current BIS IS 4707 parts (1:2020, 2:2025, 3:2025, 4:2022)
All 1,614 prohibited Annex A rows and 317 numbered/lettered restricted Annex B rows from IS 4707 Part 2:2025; official checks remain for colourants, preservatives and UV filters in Parts 1, 3 and 4.
Verification checklist
- Confirm product class and current Cosmetics Rules/gazette amendments.
- Check all applicable parts of IS 4707 by exact identity.
- Apply Schedule S/other finished-product standards where relevant.
- Verify licence/import registration, labelling and testing requirements.
Official market sources
- India Cosmetics Rules 2020Official CDSCO rules and gazette updates; standards may require separate licensed sources
- India BIS IS 4707 cosmetic ingredient standardsIndian Standards referenced by the cosmetics regulatory framework; use the controlled current editions
Verification workflow and record completeness
Before using this result in a compliance decision
- Confirm that “Cadmium nitrate; cadmium dinitrate (CAS No. 10325-94-7)” and every CAS/EC identifier refer to the material in your supplier specification.
- Confirm product class and current Cosmetics Rules/gazette amendments.
- Check all applicable parts of IS 4707 by exact identity.
- Apply Schedule S/other finished-product standards where relevant.
- Verify licence/import registration, labelling and testing requirements.
- Document the source version and recheck the regulator before manufacture, notification or market placement.
Fields available in this record
- Official substance nameAvailable
- CASAvailable
- ECNot supplied
- Separate condition textAvailable
- Effective dateAvailable
- Snapshot hash and methodAvailable
Questions this page answers
Stable citation
Cadmium nitrate; cadmium dinitrate (CAS No. 10325-94-7). IS 4707 (Part 2):2025 Annex A, entry 1603. India. Source version IS 4707 (Part 2):2025, fifth revision. CosIng Checker regulatory record: https://cosingchecker.com/regulations/in/records/16197/
Cite the regulator as the legal authority. This page is a structured evidence index and verification aid, not a substitute for the official text or professional legal assessment.
Interpretation and limits for India
This official record identifies the substance as prohibited for cosmetic use in the stated market scope.
Do not rely on a formulation containing this identity until the cited source, effective date and exact substance match have been verified.
How to interpret the legal role
The cited row forms part of a binding rule or legally incorporated list for this market.
Evidence on this page
- Recorded outcome: Prohibited
- Legal role: Binding rule
- Source version: IS 4707 (Part 2):2025, fifth revision
- Effective date: 2025-08-09
What it does not prove
The standards are separate controlled publications; absence from a locally indexed excerpt is not permission.
Further authoritative substance research
These sources can add identity, safety, exposure or hazard context. A link is not evidence that the database contains this exact substance, and none of these sources overrides the market decision above.
Cosmetic Ingredient Review safety assessments
Expert Panel conclusions, assessed ingredient groups, use conditions, dates and report documents
Independent expert review considered by FDA; not a government approval or binding market rule
Research this identity at the sourceFDA Global Substance Registration System
UNII identifiers, preferred names, substance types, codes and public substance relationships
Identity registry only; UNII availability does not imply FDA review or approval
Research this identity at the sourceILO/WHO International Chemical Safety Cards
Hazards, symptoms, first aid, storage, incompatibilities and physical properties for covered chemicals
International occupational chemical-safety reference; not cosmetic-use approval
Research this identity at the sourceJapan NITE-CHRIP
Chemical identity, Japanese and foreign legal lists, GHS hazards and exposure-related information
Chemical-management evidence; cosmetic status remains governed by the applicable MHLW standard and market rules
Research this identity at the sourceNIOSH Pocket Guide to Chemical Hazards
REL, PEL, IDLH, properties, exposure routes, symptoms, target organs, first aid and measurement methods for covered workplace chemicals
US occupational-health guidance and limits; not a cosmetic ingredient decision
Research this identity at the sourceOECD eChemPortal
Gateway to authority-owned physical-property, fate, ecotoxicity, toxicity, exposure and GHS records
Discovery gateway; each linked authority remains responsible for its data
Research this identity at the sourceUS EPA CompTox CTX APIs
API key required for importDTXSID identity, experimental and predicted properties, toxicity, bioactivity, exposure and environmental data
Scientific and computational evidence; predictions must remain labelled and do not determine cosmetic legality
Research this identity at the source