Methyl salicylate
The consolidated GB Cosmetics Regulation lists this record in Annex III.
Regulatory decision and full conditions
- Status
- Restricted
- Legal role
- Binding rule
- Regulatory summary
- The consolidated GB Cosmetics Regulation lists this record in Annex III.
- Conditions and restrictions
- (a) Rinse-off skin & hair products (except hand wash products) (b) Hand wash products (c) Leave on skin products (except face makeup, spray and aerosol body lotion, spray and aerosol deodorant and hydroalcoholic-based fragrances) and hair products (non-aerosol) (d) Lip products (e) Face makeup products (f) Eye makeup products & makeup remover (g) Toothpaste (h) Mouthwash (i) Mouth spray (j) Hydroalcoholic-based fragrances (k) Deodorant spray and aerosol products (l) Hair products (spray and aerosol) (m) Body Lotion Spray · (a) (1) 0.02% (products intended for children 0.5-1 years) (2) 0.06% (products intended for children above 1 year and adults) (b) (1) 0.02% (products intended for children 0.5-1 years) (2) 0.6% (products intended for children above 1 year and adults) (c) (1) 0.02% (products intended for children 0.5-1 years) (2) 0.06% (products intended for children above 1 year and adults) (d) (1) 0.02% (products intended for children 0.5-1 years) (2) 0.03% (products intended for children above 1 year and adults) (e) 0.05% (f) 0.002% (g) 2.5% (h) (1) 0.1% (products intended for children 6 to 10 years) (2) 0.4% (products intended for children above 10 years and adults) (i) 0.65% (j) 0.6% (k) 0.003% (l) 0.009% (m) 0.04%
Substance identity
- Official source name
- Methyl salicylate
- CAS
- 119-36-8
- EC
- 204-317-7
- Identity mapping
- cas_number
- Linked ingredient
- METHYL SALICYLATE
Linked CosIng identity data
Names and aliases
CosIng description: methyl 2-hydroxybenzoate
Recorded cosmetic function: DENATURANT, FLAVOURING, ORAL CARE, PERFUMING, SOOTHING
Function pages:DENATURANT, FLAVOURING, ORAL CARE, PERFUMING, SOOTHING
View the complete ingredient profileCross-market snapshot for this identity
Exact linked records currently present in this site. An absent market means no imported exact match, not permission to use the substance.
European Union
1 linked record · 1 with specific conditions
Open supporting recordGreat Britain
Current record1 linked record · 1 with specific conditions
Open supporting recordCanada
1 linked record · 1 with specific conditions
Open supporting recordNew Zealand
1 linked record · 1 with specific conditions
Open supporting recordSaudi Arabia
1 linked record
Open supporting recordVerified chemistry for CAS 119-36-8
Methyl Salicylate
- IUPAC name
- methyl 2-hydroxybenzoate
- Molecular formula
- C8H8O3
- Molecular weight
- 152.15 g/mol
- Exact mass
- 152.047344113 Da
- Monoisotopic mass
- 152.047344113 Da
- XLogP3
- 2.3
- Topological polar surface area
- 46.5 Ų
- Molecular complexity
- 144.0
- Formal charge
- 0
- Hydrogen-bond donors
- 1
- Hydrogen-bond acceptors
- 3
- Rotatable bonds
- 2
- Heavy atoms
- 11
- Covalent units
- 1
Names and synonyms reported to PubChem
16 more reported names
External database identifiers
- ChEBI:CHEBI:31832
- ChEMBL:CHEMBL108545
- EPA DTXSID:DTXSID5025659
- PubMed:39159849
- PubMed:36416909
- PubMed:31734321
- PubMed:28826779
- PubMed:27965148
- PubMed:27729775
- PubMed:26973745
- PubMed:26795242
- PubMed:25425092
- PubMed:25411557
- PubMed:24712652
- PubMed:23583298
Advanced structure statistics
- Defined atom stereocentres
- 0
- Undefined atom stereocentres
- 0
- Defined bond stereocentres
- 0
- Undefined bond stereocentres
- 0
- 3D pharmacophore features
- 3
- 3D rings
- 1
- 3D hydrophobes
- 0
- 3D acceptor features
- 1
- 3D donor features
- 1
- 3D anionic centres
- 0
- 3D cationic centres
- 0
- 3D conformers
- 6
- Effective 3D rotors
- 2.0
Machine-readable structure identifiers
- SMILES
COC(=O)C1=CC=CC=C1O- InChI
InChI=1S/C8H8O3/c1-11-8(10)6-4-2-3-5-7(6)9/h2-5,9H,1H3- InChIKey
OSWPMRLSEDHDFF-UHFFFAOYSA-N
Evidence from additional scientific databases
NIH PubChem PUG-View
Attributed physical-property, hazard, environmental and use annotations.
- Autoignition Temperature: 847 °F (USCG, 1999) Source: CAMEO Chemicals
- Autoignition Temperature: 850 °F Source: Hazardous Substances Data Bank (HSDB)
- Autoignition Temperature: 450 °C Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Boiling Point: 432 °F at 760 mmHg (NTP, 1992) Source: CAMEO Chemicals
- Boiling Point: 220-224 Source: DrugBank
- Boiling Point: 220-224 °C Source: Hazardous Substances Data Bank (HSDB)
- Boiling Point: 222.00 to 224.00 °C. @ 760.00 mm Hg Source: Human Metabolome Database (HMDB)
- Boiling Point: 223 °C Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Boiling Point: 222 °C Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Boiling Point: 223.3 °C @760 [mm Hg] Source: PAC Chemical Database, U.S. Department of Energy
- Color/Form: COLORLESS, YELLOWISH OR REDDISH, OILY LIQ Source: Hazardous Substances Data Bank (HSDB)
- Density: 1.174 (USCG, 1999) - Denser than water; will sink Source: CAMEO Chemicals
- Density: 1.184 @ 25 °C/25 °C Source: Hazardous Substances Data Bank (HSDB)
- Density: DENSITY OF NATURAL ESTER IS ABOUT 1.180 Source: Hazardous Substances Data Bank (HSDB)
- Density: Relative density (water = 1): 1.18 Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Density: 1.176-1.185 Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Density: 1.184 @25 °C Source: PAC Chemical Database, U.S. Department of Energy
- Dissociation Constants: pKa = 9.8 Source: Hazardous Substances Data Bank (HSDB)
- Flash Point: 205 °F (NTP, 1992) Source: CAMEO Chemicals
- Flash Point: 205 °F (96 °C) (Closed cup) Source: Hazardous Substances Data Bank (HSDB)
- Flash Point: 101 °C c.c. Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- LogP: 2.5 Source: DrugBank
- LogP: Log Kow = 2.55 Source: Hazardous Substances Data Bank (HSDB)
- LogP: 2.55 Source: Human Metabolome Database (HMDB)
- LogP: 2.55 Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Melting Point: 16.5 °F (NTP, 1992) Source: CAMEO Chemicals
- Melting Point: -8.6 Source: DrugBank
- Melting Point: -8.6 °C Source: Hazardous Substances Data Bank (HSDB)
- Melting Point: -8.6 °C Source: Human Metabolome Database (HMDB)
- Melting Point: -8 °C Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Melting Point: -8.6 °C Source: PAC Chemical Database, U.S. Department of Energy
- Odor: LIQUID HAVING THE CHARACTERISTIC ODOR OF WINTERGREEN Source: Hazardous Substances Data Bank (HSDB)
- Physical Description: Methyl salicylate appears as colorless yellowish or reddish liquid with odor of wintergreen. (USCG, 1999) Source: CAMEO Chemicals
- Physical Description: CBI; Liquid Source: EPA Chemical Data Reporting (CDR)
- Physical Description: Colorless, yellow, or red liquid with a wintergreen odor; [HSDB] Clear slightly yellow-green liquid; [MSDSonline] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Physical Description: Liquid Source: Human Metabolome Database (HMDB)
- Physical Description: COLOURLESS OR YELLOW-TO-RED OILY LIQUID WITH CHARACTERISTIC ODOUR. Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Physical Description: colourless to yellowish liquid with a characteristic wintergreen odour Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Refractive Index: INDEX OF REFRACTION: 1.5369 AT 20 °C/D; MAX ABSORPTION: 306 NM (LOG E= 3.64); SADTLER REFERENCE NUMBER: 2238 (IR, PRISM); MAX ABSORPTION (ALC): 238 NM (LOG E= 3.97) Source: Hazardous Substances Data Bank (HSDB)
- Refractive Index: 1.534-1.538 Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Solubility: less than 1 mg/mL at 66 °F (NTP, 1992) Source: CAMEO Chemicals
- Solubility: Slightly soluble Source: DrugBank
- Solubility: SOL IN CHLOROFORM, ETHER; MISCIBLE WITH ALC, GLACIAL ACETIC ACID Source: Hazardous Substances Data Bank (HSDB)
- Solubility: SOL IN DIETHYL ETHER Source: Hazardous Substances Data Bank (HSDB)
- Solubility: SOLUBLE IN MOST COMMON ORGANIC SOLVENTS Source: Hazardous Substances Data Bank (HSDB)
- Solubility: Sol in water: 0.74%w @ 30 °C Source: Hazardous Substances Data Bank (HSDB)
- Solubility: 0.7 mg/mL at 30 °C Source: Human Metabolome Database (HMDB)
- Solubility: Solubility in water, g/l at 30 °C: 0.74 (very slightly soluble) Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Solubility: slightly soluble in water; soluble in organic solvents, oils Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Solubility: miscible at room temperature (in ethanol) Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
- Vapor Pressure: 0.0975 mmHg at 68 °F ; 1 mmHg at 129 °F (NTP, 1992) Source: CAMEO Chemicals
- Vapor Pressure: 0.03 [mmHg] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Vapor Pressure: Vapor pressure = 0.0343 mm Hg @ 25 °C Source: Hazardous Substances Data Bank (HSDB)
- Vapor Pressure: Vapor pressure, Pa at 20 °C: 13 Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Vapor Pressure: 0.0343 [mm Hg] @25 °C Source: PAC Chemical Database, U.S. Department of Energy
- Viscosity: 1.535 mPa*s at 25 °C Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- Carcinogen Classification: No indication of carcinogenicity to humans (not listed by IARC). Source: Toxin and Toxin Target Database (T3DB)
- Exposure Routes: The substance can be absorbed into the body by inhalation, through the skin and by ingestion. Source: ILO-WHO International Chemical Safety Cards (ICSCs)
- First Aid: EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.; SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.; INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) shou Source: CAMEO Chemicals
- Signal: Warning Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
- GHS Hazard Statements: H302: Harmful if swallowed [Warning Acute toxicity, oral]; H317: May cause an allergic skin reaction [Warning Sensitization, Skin]; H361d: Suspected of damaging the unborn child [Warning Reproductive toxicity]; H412: Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
- Precautionary Statement Codes: P203, P261, P264, P270, P272, P273, P280, P301+P317, P302+P352, P318, P321, P330, P333+P317, P362+P364, P405, and P501 (click each P-code to see the statement) Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
- Note: This chemical does not meet GHS hazard criteria for 0.3% (6 of 2210) of reports. Source: European Chemicals Agency (ECHA)
- Signal: Warning Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H302 (96.9%): Harmful if swallowed [Warning Acute toxicity, oral] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 2210 reports by companies from 32 notifications to the ECHA C&L Inventory.; Reported as not meeting GHS hazard criteria per 6 of 2210 reports by companies.; There are 31 notifications provided by 2204 of 2210 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- Note: This chemical does not meet GHS hazard criteria for 2.4% (37 of 1530) of reports. Source: European Chemicals Agency (ECHA)
- GHS Hazard Statements: H302 (97.5%): Harmful if swallowed [Warning Acute toxicity, oral]; H319 (91.1%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] Source: European Chemicals Agency (ECHA)
- Precautionary Statement Codes: P264, P264+P265, P270, P280, P301+P317, P305+P351+P338, P330, P337+P317, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
- ECHA C&L Notifications Summary: Aggregated GHS information provided per 1530 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 37 of 1530 reports by companies.; There are 9 notifications provided by 1493 of 1530 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
- NFPA Health Rating: 1 - Materials that, under emergency conditions, can cause significant irritation. Source: Hazardous Substances Data Bank (HSDB)
- NFPA Fire Rating: 1 - Materials that must be preheated before ignition can occur. Materials require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur. Source: Hazardous Substances Data Bank (HSDB)
- NFPA Instability Rating: 0 - Materials that in themselves are normally stable, even under fire conditions. Source: Hazardous Substances Data Bank (HSDB)
- Cosmetic Ingredient Review Conclusion: The Panel concluded that the following ingredients are safe in cosmetics in the present practices of use and concentration described in the safety assessment, when formulated to be non-irritating and non-sensitizing, which may be based on a quantitative risk assessment (QRA)...Methyl Salicylate... Source: Cosmetic Ingredient Review (CIR)
- Cosmetic Ingredient Review Finding(s): Safe for use in cosmetics, with qualifications Source: Cosmetic Ingredient Review (CIR)
- Environmental Bioconcentration: The log octanol/water partition coefficient for methyl salicylate is 2.55(1). The BCF estimated from this log Kow using a regression equation is 4 which indicates that the ester will not bioconcentrate in fish(SRC). Source: Hazardous Substances Data Bank (HSDB)
- Environmental Fate: TERRESTRIAL FATE: If released on soil, methyl salicylate would readily leach. It would also be expected to partially volatilize from dry soil and photolyze on the soil surface. Based on the results of sceening tests, it would be expected to readily biodregrade. Chemical hydrolysis may be important in alkaline soil. (SRC) Source: Hazardous Substances Data Bank (HSDB)
- Environmental Fate: AQUATIC FATE: Methyl salicylate is readily biodegradable in screening tests and may be expected to biodegrade in surface waters. Methyl salicylate is expected to hydrolyze in water, the hydrolysis rate increasing with pH. At pH 7.5, its hydrolysis half-life is estimated to be 14.1 days(1,2,SRC). Methyl salicylate will react with singlet oxygen in natural surface waters resulting in a half-life of about 52 hr(3). Methyl salicylate absorbs UV radiation >290 nm and therefore may undergo direct photolysis under environmental conditions. Based on an estimated Henry's Law constant of 9.3X10-7 atm-cu-m/mol(4,5,SRC), a volatilization half-life of 49 days would be expected in a model river(SRC). Source: Hazardous Substances Data Bank (HSDB)
- Environmental Fate: ATMOSPHERIC FATE: Methyl salicylate reacts with photochemically-produced hydroxyl radicals in the atmosphere resulting in an estimated half-life of 1.4 days(1,SRC). It is fairly soluble in water, 7400 mg/L(2) and may be washed out by rain. Source: Hazardous Substances Data Bank (HSDB)
- Consumer Uses: Fragrance; Not Known or Reasonably Ascertainable; Other Source: EPA Chemical Data Reporting (CDR)
- Industry Uses: Not Known or Reasonably Ascertainable; Fragrance; Flavoring and nutrient; Intermediates Source: EPA Chemical Data Reporting (CDR)
- Cosmetic Ingredient Review Link: CIR ingredient: Methyl Salicylate Source: Cosmetic Ingredient Review (CIR)
- Sources/Uses: Used as food flavor (restricted by FDA); [Hawley] Used as flavor, UV-absorber in sunscreens, fragrance, solvent (insecticides, polishes, and inks), antiseptic in oral hygiene products, dye carrier, UV light stabilizer in acrylic resins, and topical analgesic in human and veterinary medicine; [HSDB] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Industrial Processes with risk of exposure: Using Disinfectants or Biocides [Category: Clean] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
- Uses: OIL: IN FERN AND CYPRESS TYPE PERFUMES & IN TOOTHPASTE Source: Hazardous Substances Data Bank (HSDB)
- Uses: MEDICATION (VET) Source: Hazardous Substances Data Bank (HSDB)
- Uses: MEDICATION Source: Hazardous Substances Data Bank (HSDB)
- Uses: UV-absorber in sunburn lotions; flavor in foods, beverages, pharmaceuticals; odorant Source: Hazardous Substances Data Bank (HSDB)
- Uses: For more Uses (Complete) data for METHYL SALICYLATE (9 total), please visit the HSDB record page. Source: Hazardous Substances Data Bank (HSDB)
Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record
Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.
Additional source coverage and match status
| Source | Result | Checked |
|---|---|---|
| NIH PubChem PUG-View | Exact match | 2026-08-31 |
A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Official source and provenance
- Registered source
- Great Britain Cosmetics Regulation — consolidated Annexes II–VI and amendments
- Source reference
- GB Cosmetics Regulation, Annex III, entry 324
- Source record ID
III-324- Source version
- 2026-08-15
- Source language
- English
- Translation status
- Original is English
- Effective date
- 2026-08-15
- Source updated
- 2026-08-19
- Snapshot checked
- 2026-08-30 04:51 UTC
- Validation method
- legislation.gov.uk XML table parse; {'II': 1758, 'III': 326, 'IV': 154, 'V': 57, 'VI': 34}
- SHA-256
e3a386d950f54c6e7a7f9e784d1bd46e52de725137e89d5630709824475215d8
Registered dataset notes
- Dataset coverage
- Complete consolidated GB Annexes II–VI, with later amendments versioned separately
- Authority note
- Binding GB schedules and versioned amendments to retained Regulation 1223/2009; applies to England, Wales and Scotland, not Northern Ireland
- Source licence
- Open Government Licence v3.0 / Crown copyright
- Attribution
- Contains public sector information licensed under the Open Government Licence v3.0.
How this record fits the market dataset
Status distribution
Condition text is present on 517 of 2329 current records. An empty condition field is interpreted according to the record type above; it is never converted into an unrestricted-use claim.
Great Britain market context
Complete consolidated annex dataset
Coverage version: GB retained Regulation 1223/2009 schedules, effective 15 August 2026
Current consolidated Annexes II–VI for England, Scotland and Wales.
Verification checklist
- Confirm INCI/CAS/EC identity.
- Review every current GB Annex II–VI match.
- Check commencement dates and later statutory instruments.
- Verify SCPN, responsible-person, safety-report and labelling duties.
Official market sources
- Great Britain Cosmetics Regulation — consolidated Annexes II–VI and amendmentsBinding GB schedules and versioned amendments to retained Regulation 1223/2009; applies to England, Wales and Scotland, not Northern Ireland
Verification workflow and record completeness
Before using this result in a compliance decision
- Confirm that “Methyl salicylate” and every CAS/EC identifier refer to the material in your supplier specification.
- Confirm INCI/CAS/EC identity.
- Review every current GB Annex II–VI match.
- Check commencement dates and later statutory instruments.
- Verify SCPN, responsible-person, safety-report and labelling duties.
- Document the source version and recheck the regulator before manufacture, notification or market placement.
Fields available in this record
- Official substance nameAvailable
- CASAvailable
- ECAvailable
- Separate condition textAvailable
- Effective dateAvailable
- Snapshot hash and methodAvailable
Questions this page answers
Stable citation
Methyl salicylate. GB Cosmetics Regulation, Annex III, entry 324. Great Britain. Source version 2026-08-15. CosIng Checker regulatory record: https://cosingchecker.com/regulations/gb/records/6440/
Cite the regulator as the legal authority. This page is a structured evidence index and verification aid, not a substitute for the official text or professional legal assessment.
Interpretation and limits for Great Britain
This substance is not unrestricted: cosmetic use is subject to the conditions in the cited official record.
Check product type, body area, concentration, purity and warning requirements before deciding whether a formulation is compliant.
How to interpret the legal role
The cited row forms part of a binding rule or legally incorporated list for this market.
Evidence on this page
- Recorded outcome: Restricted
- Legal role: Binding rule
- Source version: 2026-08-15
- Effective date: 2026-08-15
What it does not prove
No annex match is not approval and does not cover Northern Ireland, which follows the applicable EU framework.
Further authoritative substance research
These sources can add identity, safety, exposure or hazard context. A link is not evidence that the database contains this exact substance, and none of these sources overrides the market decision above.
Cosmetic Ingredient Review safety assessments
Expert Panel conclusions, assessed ingredient groups, use conditions, dates and report documents
Independent expert review considered by FDA; not a government approval or binding market rule
Research this identity at the sourceFDA Global Substance Registration System
UNII identifiers, preferred names, substance types, codes and public substance relationships
Identity registry only; UNII availability does not imply FDA review or approval
Research this identity at the sourceILO/WHO International Chemical Safety Cards
Hazards, symptoms, first aid, storage, incompatibilities and physical properties for covered chemicals
International occupational chemical-safety reference; not cosmetic-use approval
Research this identity at the sourceJapan NITE-CHRIP
Chemical identity, Japanese and foreign legal lists, GHS hazards and exposure-related information
Chemical-management evidence; cosmetic status remains governed by the applicable MHLW standard and market rules
Research this identity at the sourceNIOSH Pocket Guide to Chemical Hazards
REL, PEL, IDLH, properties, exposure routes, symptoms, target organs, first aid and measurement methods for covered workplace chemicals
US occupational-health guidance and limits; not a cosmetic ingredient decision
Research this identity at the sourceOECD eChemPortal
Gateway to authority-owned physical-property, fate, ecotoxicity, toxicity, exposure and GHS records
Discovery gateway; each linked authority remains responsible for its data
Research this identity at the sourceUS EPA CompTox CTX APIs
API key required for importDTXSID identity, experimental and predicted properties, toxicity, bioactivity, exposure and environmental data
Scientific and computational evidence; predictions must remain labelled and do not determine cosmetic legality
Research this identity at the source