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ProhibitedBinding ruleGBOriginal is EnglishOfficial-source import checked

Pentachlorophenol and its alkali salts

The consolidated GB Cosmetics Regulation lists this record in Annex II.

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Regulatory decision and full conditions

Status
Prohibited
Legal role
Binding rule
Regulatory summary
The consolidated GB Cosmetics Regulation lists this record in Annex II.
Conditions and restrictions
A prohibition entry may contain no separate condition text because the regulatory outcome is the prohibition itself. Open the cited source and apply the market-wide requirements below.

Substance identity

Official source name
Pentachlorophenol and its alkali salts
CAS
87-86-5; 131-52-2; 7778-73-6
EC
201-778-6; 205-025-2; 231-911-3
Identity mapping
standalone:official_gb_annex
Search this identity across the siteCAS 87-86-5CAS 131-52-2CAS 7778-73-6EC 201-778-6EC 205-025-2EC 231-911-3

Cross-market snapshot for this identity

Exact linked records currently present in this site. An absent market means no imported exact match, not permission to use the substance.

9 market datasets
PubChem 2D chemical structure for CAS 131-52-2
CAS 131-52-2PubChem CID 23663539

Verified chemistry for CAS 131-52-2

Sodium pentachlorophenolate

IUPAC name
sodium 2,3,4,5,6-pentachlorophenolate
Molecular formula
C6Cl5NaO
Molecular weight
288.3 g/mol
Exact mass
287.825997 Da
Monoisotopic mass
285.828947 Da
Topological polar surface area
23.1 Ų
Molecular complexity
155.0
Formal charge
0
Hydrogen-bond donors
0
Hydrogen-bond acceptors
1
Rotatable bonds
0
Heavy atoms
13
Covalent units
2

Names and synonyms reported to PubChem

Sodium pentachlorophenateSodium pentachlorophenolWeedbeadsPkhfnSodium pentachlorophenoxideSantobrite DDowicide GPreventol PN
16 more reported names
Witophen NMystox DPCP Sodium saltPCP-SodiumSodium PCPPentanot 25SantobriteDow dormant fungicideSapco 25Caswell No. 784Sodium pentachlorphenatePentachlorophenate sodiumPentachlorophenoxy sodiumPENTACHLOROPHENOL, SODIUM SALTPentachlorphenol sodium saltSodium, (pentachlorophenoxy)-
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
C1(=C(C(=C(C(=C1Cl)Cl)Cl)Cl)Cl)[O-].[Na+]
InChI
InChI=1S/C6HCl5O.Na/c7-1-2(8)4(10)6(12)5(11)3(1)9;/h12H;/q;+1/p-1
InChIKey
HCJLVWUMMKIQIM-UHFFFAOYSA-M

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match23663539

Attributed physical-property, hazard, environmental and use annotations.

  • First Aid: Signs and Symptoms of Sodium Pentachlorophenate Exposure: Signs and symptoms of sodium pentachlorophenate exposure include skin irritation, irritation and burning of eyes, numbness and opacity of the cornea, upper respiratory tract irritation, pain in chest, coughing, sneezing, rapid breathing, difficulty in breathing, and bronchitis. Contact dermatitis may be observed after severe exposure. Profuse sweating, headache, weakness, loss of appetite, abdominal pain, nausea, cardiac dilatation, tachycardia (rapid heart beat), and cardiac failure may occur. High fever may be present, and exposed individual may experience an intense thirst, although this may be masked by nausea and vomiting. Declining alertness may progress to stupor, convulsions, and coma. Ingestion may be followed by delayed scar tissue formation, which may later cause problems with swallowing and stomach filling and emptying.; Emergency Life-Support Procedures: Acute exposure to sodium pentachlorophenate may require decontamination and life support for the victims. Emergency personnel should wear protective clothing appropriate to the type and degree of contamination. Air-purifying or supplied-air respiratory equipment Source: CAMEO Chemicals
  • ERG2024, Guide 154 (Sodium pentachlorophenate): General First Aid:; · Call 911 or emergency medical service.; · Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and avoid contamination.; · Move victim to fresh air if it can be done safely.; · Administer oxygen if breathing is difficult.; · If victim is not breathing:; -- DO NOT perform mouth-to-mouth resuscitation; the victim may have ingested or inhaled the substance.; -- If equipped and pulse detected, wash face and mouth, then give artificial respiration using a proper respiratory medical device (bag-valve mask, pocket mask equipped with a one-way valve or other device).; -- If no pulse detected or no respiratory medical device available, provide continuous compressions. Conduct a pulse check every two minutes or monitor for any signs of spontaneous respirations.; · Remove and isolate contaminated clothing and shoes.; · For minor skin contact, avoid spreading material on unaffected skin.; · In case of contact with substance, remove immediately by flushing skin or eyes with running water for at least 20 minutes.; · For severe burns, immediate medical attention is required.; · Effects of exposure (inhalation, ingestion, Source: Emergency Response Guidebook (ERG)
  • Signal: Danger Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • GHS Hazard Statements: H301: Toxic if swallowed [Danger Acute toxicity, oral]; H311: Toxic in contact with skin [Danger Acute toxicity, dermal]; H315: Causes skin irritation [Warning Skin corrosion/irritation]; H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H330: Fatal if inhaled [Danger Acute toxicity, inhalation]; H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]; H351: Suspected of causing cancer [Warning Carcinogenicity]; H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]; H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Precautionary Statement Codes: P203, P260, P261, P262, P264, P264+P265, P270, P271, P273, P280, P284, P301+P316, P302+P352, P304+P340, P305+P351+P338, P316, P318, P319, P320, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement) Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Signal: Danger Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H301+H311 (61.8%): Toxic if swallowed or in contact with skin [Danger Acute toxicity, oral; acute toxicity, dermal]; H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]; H311 (100%): Toxic in contact with skin [Danger Acute toxicity, dermal]; H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]; H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H330 (100%): Fatal if inhaled [Danger Acute toxicity, inhalation]; H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]; H351 (100%): Suspected of causing cancer [Warning Carcinogenicity]; H400 (100%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]; H410 (100%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P203, P260, P261, P262, P264, P264+P265, P270, P271, P273, P280, P284, P301+P316, P302+P352, P304+P340, P305+P351+P338, P316, P318, P319, P320, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 170 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: NITE-CMC
  • GHS Hazard Statements: H301: Toxic if swallowed [Danger Acute toxicity, oral]; H310: Fatal in contact with skin [Danger Acute toxicity, dermal]; H315: Causes skin irritation [Warning Skin corrosion/irritation]; H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]; H330: Fatal if inhaled [Danger Acute toxicity, inhalation]; H350: May cause cancer [Danger Carcinogenicity]; H360: May damage fertility or the unborn child [Danger Reproductive toxicity]; H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]; H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure] Source: NITE-CMC
  • Precautionary Statement Codes: P203, P260, P262, P264, P264+P265, P270, P271, P280, P284, P301+P316, P302+P352, P304+P340, P305+P354+P338, P308+P316, P316, P317, P318, P319, P320, P321, P330, P332+P317, P361+P364, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
  • GHS Hazard Statements: H301: Toxic if swallowed [Danger Acute toxicity, oral]; H310: Fatal in contact with skin [Danger Acute toxicity, dermal]; H315: Causes skin irritation [Warning Skin corrosion/irritation]; H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H330: Fatal if inhaled [Danger Acute toxicity, inhalation]; H351: Suspected of causing cancer [Warning Carcinogenicity]; H361: Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]; H371: May cause damage to organs [Warning Specific target organ toxicity, single exposure]; H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]; H373: May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure] Source: NITE-CMC
  • Precautionary Statement Codes: P203, P260, P262, P264, P264+P265, P270, P271, P280, P284, P301+P316, P302+P352, P304+P340, P305+P351+P338, P308+P316, P316, P318, P319, P320, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
  • Health Effects: Acute exposure to cholinesterase inhibitors can cause a cholinergic crisis characterized by severe nausea/vomiting, salivation, sweating, bradycardia, hypotension, collapse, and convulsions. Increasing muscle weakness is a possibility and may result in death if respiratory muscles are involved. Accumulation of ACh at motor nerves causes overstimulation of nicotinic expression at the neuromuscular junction. When this occurs symptoms such as muscle weakness, fatigue, muscle cramps, fasciculation, and paralysis can be seen. When there is an accumulation of ACh at autonomic ganglia this causes overstimulation of nicotinic expression in the sympathetic system. Symptoms associated with this are hypertension, and hypoglycemia. Overstimulation of nicotinic acetylcholine receptors in the central nervous system, due to accumulation of ACh, results in anxiety, headache, convulsions, ataxia, depression of respiration and circulation, tremor, general weakness, and potentially coma. When there is expression of muscarinic overstimulation due to excess acetylcholine at muscarinic acetylcholine receptors symptoms of visual disturbances, tightness in chest, wheezing due to bronchoconstriction, incre Source: Toxin and Toxin Target Database (T3DB)
  • Toxicity Summary: Pentachlorophenol is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinesterase. Because of its essential function, chemicals that interfere with the action of acetylcholinesterase are potent neurotoxins, causing excessive salivation and eye-watering in low doses, followed by muscle spasms and ultimately death. Nerve gases and many substances used in insecticides have been shown to act by binding a serine in the active site of acetylcholine esterase, inhibiting the enzyme completely. Acetylcholine esterase breaks down the neurotransmitter acetylcholine, which is released at nerve and muscle junctions, in order to allow the muscle or organ to relax. The result of acetylcholine esterase inhibition is that acetylcholine builds up and continues to act so that any nerve impulses are continually transmitted and muscle contractions do not stop. Among the most common acetylcholinesterase inhibitors are phosphorus-based compounds, which are designed to bind to the active site of the enzyme. The structural requirements are a phosphorus atom bearing two lipophilic groups, a leaving group (such a Source: Toxin and Toxin Target Database (T3DB)
  • Environmental Bioconcentration: Rainbow trout exposed to waterborne sodium pentachlorophenate averaging 35 and 660 ng/L for about 115 days accumulated levels of pentachlorophenate that were related to the concentration and duration of exposure. Pentachlorophenate levels in organs (liver and gall bladder), the remaining fish, and the percent of total pentachlorophenate in the organs remained relatively uniform among the control fish over the 115 day period. Fish exposed to 35 ng/L contained slightly higher pentachlorophenate levels with a higher percentage found in the organs. The highest levels of pentachlorophenate occurred in fish exposed to 660 ng/L where concentration in the organs averaged 2200 ug/kg after 115 days. Thus, uptake from water is an important pathway for the accumulation of pentachlorophenate by rainbow trout. Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: Pentachlorophenate disappeared from the water of microcosms simulating some of the characteristics of littoral zones during the first 6 wk after exposure to a single application of 41 ug/l (14)C-labeled sodium pentachlorophenate. Concn of inorganic (14)C in water samples increased during this period and subsequently declined. The total (14)C residues in the water declined approx 2% per day throughout the experiment and radioactive residues in macrophytes increased linearly between days 1 and 35, reaching concn greater than 700 times the initial concn in water. Concn of (14)C residues in macrophytes dropped rapidly after the 8th week of the experiment. Some (14)C pentachlorophenate was degraded to (14)C carbon dioxide and photosynthetic fixation of (14)C carbon dioxide occurred. At the end of the experiment, 40-43% of the radioactivity was present in benthic sediments and approx 5% was recovered in scrapings of mineral precipitates and algae from the walls of the microcosms. About 40% of the applied radioactivity was not detected in microcosm components and was presumably lost to the atmosphere during the 180 day exposure period. Source: Hazardous Substances Data Bank (HSDB)
  • Sources/Uses: Used as bactericide, fungicide, and disinfectant (cooling towers, adhesives, construction materials, leather tanning, paints, petroleum drilling muds, photographic solutions, pulp and paper processing, textiles, water treatment, and industrial re-circulating water); [HSDB] Used as herbicide; [Hawley] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Restricted Notes: Not currently registered as pesticide with the EPA for use in the US; [HSDB] Banned in the EU as pesticide for plant protection; Use severely restricted as a biocide; [eChemPortal: ESIS] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Industrial Processes with risk of exposure: Petroleum Production and Refining [Category: Industry]; Pulp and Paper Processing [Category: Industry]; Textiles (Fiber & Fabric Manufacturing) [Category: Industry]; Painting (Pigments, Binders, and Biocides) [Category: Paint]; Working with Glues and Adhesives [Category: Other]; Using Disinfectants or Biocides [Category: Clean]; Farming (Pesticides) [Category: Industry]; Sewer and Wastewater Treatment [Category: Industry]; Leather Tanning and Processing [Category: Industry]; Photographic Processing [Category: Other] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Uses: For pentachlorophenol, sodium salt (USEPA/OPP Pesticide Code: 063003) there are 0 labels match. /SRP: Not registered for current use in the U.S., but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses./ Source: Hazardous Substances Data Bank (HSDB)
  • Uses: The active ingredient is no longer contained in any registered pesticide products ... "cancelled." Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Fungicide /non-USA/ Source: Hazardous Substances Data Bank (HSDB)
  • Uses: PCP or its sodium salt have also been used as a herbicide and dessicant for forage seed crops, a herbicide for non-food vegetation control, a biocide in the post-harvest washing of fruit, and as an insecticide for use in beehives, seed plots, and greenhouses. PCP was formerly used as a herbicide in paddy and upland rice fields, particularly in Japan. /Former/ Source: Hazardous Substances Data Bank (HSDB)
  • Uses: For more Uses (Complete) data for PENTACHLOROPHENOL, SODIUM SALT (8 total), please visit the HSDB record page. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Pentachlorophenol is a restrictively used pesticide and is used industrially as a wood preservative for utility poles, railroad ties, and wharf pilings. (L127) Source: Toxin and Toxin Target Database (T3DB)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 7778-73-6
CAS 7778-73-6PubChem CID 23669628

Verified chemistry for CAS 7778-73-6

Potassium pentachlorophenolate

IUPAC name
potassium 2,3,4,5,6-pentachlorophenolate
Molecular formula
C6Cl5KO
Molecular weight
304.4 g/mol
Exact mass
303.799934 Da
Monoisotopic mass
301.802885 Da
Topological polar surface area
23.1 Ų
Molecular complexity
155.0
Formal charge
0
Hydrogen-bond donors
0
Hydrogen-bond acceptors
1
Rotatable bonds
0
Heavy atoms
13
Covalent units
2

Names and synonyms reported to PubChem

Phenol, 2,3,4,5,6-pentachloro-, potassium salt (1:1)RefChem:867959Potassium pentachlorophenatePotassium pentachlorophenoxidePotassium, (pentachlorophenoxy)-Phenol, pentachloro-, potassium saltAC6W3L17DXCaswell No. 641A
6 more reported names
Pentachlorophenol potassium saltEINECS 231-911-3UNII-AC6W3L17DXEPA Pesticide Chemical Code 063002Pentachlorophenol, potassium saltPhenol, pentachloro-, potassium deriv.
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D conformers
0
Machine-readable structure identifiers
SMILES
C1(=C(C(=C(C(=C1Cl)Cl)Cl)Cl)Cl)[O-].[K+]
InChI
InChI=1S/C6HCl5O.K/c7-1-2(8)4(10)6(12)5(11)3(1)9;/h12H;/q;+1/p-1
InChIKey
WYQQGYULUDOPRU-UHFFFAOYSA-M

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 87-86-5
CAS 87-86-5PubChem CID 992

Verified chemistry for CAS 87-86-5

Pentachlorophenol

Pentachlorophenol is a chlorophenol that is phenol substituted by 5 chloro groups. It has a role as a human xenobiotic metabolite. It is a chlorophenol, an organochlorine pesticide, a member of pentachlorobenzenes and an aromatic fungicide. It is functionally related to a pentachlorobenzene. It is a conjugate acid of a pentachlorophenolate. — ChEBI

IUPAC name
2,3,4,5,6-pentachlorophenol
Molecular formula
C6HCl5O
Molecular weight
266.3 g/mol
Exact mass
265.844053 Da
Monoisotopic mass
263.847003 Da
XLogP3
5.1
Topological polar surface area
20.2 Ų
Molecular complexity
150.0
Formal charge
0
Hydrogen-bond donors
1
Hydrogen-bond acceptors
1
Rotatable bonds
0
Heavy atoms
12
Covalent units
1

Names and synonyms reported to PubChem

ChlorophenLauxtolPenchlorolPermitePeratoxPentachlorophenatePermacidePermagard
16 more reported names
SantophenDowicide 7DurotoxFungifenLiropremPentaconPermasanSinituhoPenwarPhenol, pentachloro-Santophen 20Glazd pentaGrundier arbezolPenta-KilChem-TolTerm-i-trol
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D pharmacophore features
2
3D rings
1
3D hydrophobes
0
3D acceptor features
0
3D donor features
1
3D anionic centres
0
3D cationic centres
0
3D conformers
1
Effective 3D rotors
0.0
Machine-readable structure identifiers
SMILES
C1(=C(C(=C(C(=C1Cl)Cl)Cl)Cl)Cl)O
InChI
InChI=1S/C6HCl5O/c7-1-2(8)4(10)6(12)5(11)3(1)9/h12H
InChIKey
IZUPBVBPLAPZRR-UHFFFAOYSA-N

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Official source and provenance

Registered source
Great Britain Cosmetics Regulation — consolidated Annexes II–VI and amendments
Source reference
GB Cosmetics Regulation, Annex II, entry 1012
Source record ID
II-1012
Source version
2026-08-15
Source language
English
Translation status
Original is English
Effective date
2026-08-15
Source updated
2026-08-19
Snapshot checked
2026-08-30 04:51 UTC
Validation method
legislation.gov.uk XML table parse; {'II': 1758, 'III': 326, 'IV': 154, 'V': 57, 'VI': 34}
SHA-256
e3a386d950f54c6e7a7f9e784d1bd46e52de725137e89d5630709824475215d8

Registered dataset notes

Dataset coverage
Complete consolidated GB Annexes II–VI, with later amendments versioned separately
Authority note
Binding GB schedules and versioned amendments to retained Regulation 1223/2009; applies to England, Wales and Scotland, not Northern Ireland
Source licence
Open Government Licence v3.0 / Crown copyright
Attribution
Contains public sector information licensed under the Open Government Licence v3.0.
Inspect the exact official sourceRegulator guidance

How this record fits the market dataset

2329
current Great Britain records
1758
records marked Prohibited
2329
records from this source version
2015
market records with CAS identity

Status distribution

Permitted list with conditions: 245Prohibited: 1758Restricted: 326

Condition text is present on 517 of 2329 current records. An empty condition field is interpreted according to the record type above; it is never converted into an unrestricted-use claim.

Great Britain market context

Complete consolidated annex dataset

Coverage version: GB retained Regulation 1223/2009 schedules, effective 15 August 2026

Current consolidated Annexes II–VI for England, Scotland and Wales.

Verification checklist

  1. Confirm INCI/CAS/EC identity.
  2. Review every current GB Annex II–VI match.
  3. Check commencement dates and later statutory instruments.
  4. Verify SCPN, responsible-person, safety-report and labelling duties.

Official market sources

Verification workflow and record completeness

Before using this result in a compliance decision

  1. Confirm that “Pentachlorophenol and its alkali salts” and every CAS/EC identifier refer to the material in your supplier specification.
  2. Confirm INCI/CAS/EC identity.
  3. Review every current GB Annex II–VI match.
  4. Check commencement dates and later statutory instruments.
  5. Verify SCPN, responsible-person, safety-report and labelling duties.
  6. Document the source version and recheck the regulator before manufacture, notification or market placement.

Fields available in this record

  • Official substance nameAvailable
  • CASAvailable
  • ECAvailable
  • Separate condition textNot present in source row
  • Effective dateAvailable
  • Snapshot hash and methodAvailable

Questions this page answers

This official record identifies the substance as prohibited for cosmetic use in the stated market scope. Do not rely on a formulation containing this identity until the cited source, effective date and exact substance match have been verified.

A prohibition entry may contain no separate condition text because the regulatory outcome is the prohibition itself. No annex match is not approval and does not cover Northern Ireland, which follows the applicable EU framework.

The record cites GB Cosmetics Regulation, Annex II, entry 1012, source version 2026-08-15. Open the official source.

No. CAS helps resolve identity, but jurisdictions can classify the same substance differently and can apply different product scopes, limits, warnings and transition dates.

Stable citation

Pentachlorophenol and its alkali salts. GB Cosmetics Regulation, Annex II, entry 1012. Great Britain. Source version 2026-08-15. CosIng Checker regulatory record: https://cosingchecker.com/regulations/gb/records/5367/

Cite the regulator as the legal authority. This page is a structured evidence index and verification aid, not a substitute for the official text or professional legal assessment.

Interpretation and limits for Great Britain

This official record identifies the substance as prohibited for cosmetic use in the stated market scope.

Do not rely on a formulation containing this identity until the cited source, effective date and exact substance match have been verified.

How to interpret the legal role

The cited row forms part of a binding rule or legally incorporated list for this market.

Evidence on this page

  • Recorded outcome: Prohibited
  • Legal role: Binding rule
  • Source version: 2026-08-15
  • Effective date: 2026-08-15

What it does not prove

No annex match is not approval and does not cover Northern Ireland, which follows the applicable EU framework.

Further authoritative substance research

These sources can add identity, safety, exposure or hazard context. A link is not evidence that the database contains this exact substance, and none of these sources overrides the market decision above.

Cosmetic Ingredient Review safety assessments

Expert Panel conclusions, assessed ingredient groups, use conditions, dates and report documents

Independent expert review considered by FDA; not a government approval or binding market rule

Research this identity at the source

FDA Global Substance Registration System

UNII identifiers, preferred names, substance types, codes and public substance relationships

Identity registry only; UNII availability does not imply FDA review or approval

Research this identity at the source

ILO/WHO International Chemical Safety Cards

Hazards, symptoms, first aid, storage, incompatibilities and physical properties for covered chemicals

International occupational chemical-safety reference; not cosmetic-use approval

Research this identity at the source

Japan NITE-CHRIP

Chemical identity, Japanese and foreign legal lists, GHS hazards and exposure-related information

Chemical-management evidence; cosmetic status remains governed by the applicable MHLW standard and market rules

Research this identity at the source

NIOSH Pocket Guide to Chemical Hazards

REL, PEL, IDLH, properties, exposure routes, symptoms, target organs, first aid and measurement methods for covered workplace chemicals

US occupational-health guidance and limits; not a cosmetic ingredient decision

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OECD eChemPortal

Gateway to authority-owned physical-property, fate, ecotoxicity, toxicity, exposure and GHS records

Discovery gateway; each linked authority remains responsible for its data

Research this identity at the source

US EPA CompTox CTX APIs

API key required for import

DTXSID identity, experimental and predicted properties, toxicity, bioactivity, exposure and environmental data

Scientific and computational evidence; predictions must remain labelled and do not determine cosmetic legality

Research this identity at the source