Solvent Red 49:1
Canada Hotlist: Solvent Red 49:1
Health Canada lists this ingredient as prohibited for use in cosmetic products.
Regulatory decision and full conditions
- Status
- Prohibited
- Legal role
- Official guidance
- Regulatory summary
- Health Canada lists this ingredient as prohibited for use in cosmetic products.
- Conditions and restrictions
- Synonyms or related compounds: CI 45170:1; Rhodamine B-Stearate
Substance identity
- Official source name
- Solvent Red 49:1
- CAS
- 6373-07-5
- EC
- 228-908-4
- Identity mapping
- cas_number
- Linked ingredient
- SOLVENT RED 49:1
Linked CosIng identity data
Names and aliases
CosIng description: N-[9-(2-Carboxyphenyl)-6-(Diethylamino)-3H-Xanthen-3-ylidene]-N-Ethylethanaminium octadecanoate
EU inventory restriction note: II/398
Recorded cosmetic function: COLORANT
Function pages:COLORANT
View the complete ingredient profileCross-market snapshot for this identity
Exact linked records currently present in this site. An absent market means no imported exact match, not permission to use the substance.
European Union
1 linked record
Open supporting recordCanada
Current record1 linked record · 1 with specific conditions
Open supporting recordBrazil
1 linked record · 1 with specific conditions
Open supporting recordVerified chemistry for CAS 6373-07-5
Rhodamine B Stearate
- IUPAC name
- [9-(2-carboxyphenyl)-6-(diethylamino)xanthen-3-ylidene]-diethylazanium;octadecanoate
- Molecular formula
- C46H66N2O5
- Molecular weight
- 727.0 g/mol
- Exact mass
- 726.49717321 Da
- Monoisotopic mass
- 726.49717321 Da
- Topological polar surface area
- 92.9 Ų
- Molecular complexity
- 1010.0
- Formal charge
- 0
- Hydrogen-bond donors
- 1
- Hydrogen-bond acceptors
- 6
- Rotatable bonds
- 22
- Heavy atoms
- 53
- Covalent units
- 2
Names and synonyms reported to PubChem
16 more reported names
External database identifiers
- EPA DTXSID:DTXSID2064284
Advanced structure statistics
- Defined atom stereocentres
- 0
- Undefined atom stereocentres
- 0
- Defined bond stereocentres
- 0
- Undefined bond stereocentres
- 0
- 3D conformers
- 0
Machine-readable structure identifiers
- SMILES
CCCCCCCCCCCCCCCCCC(=O)[O-].CCN(CC)C1=CC2=C(C=C1)C(=C3C=CC(=[N+](CC)CC)C=C3O2)C4=CC=CC=C4C(=O)O- InChI
InChI=1S/C28H30N2O3.C18H36O2/c1-5-29(6-2)19-13-15-23-25(17-19)33-26-18-20(30(7-3)8-4)14-16-24(26)27(23)21-11-9-10-12-22(21)28(31)32;1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-18H,5-8H2,1-4H3;2-17H2,1H3,(H,19,20)- InChIKey
CELKVAQKCIJCLK-UHFFFAOYSA-N
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Official source and provenance
- Registered source
- Health Canada Cosmetic Ingredient Hotlist
- Source reference
- Hotlist prohibited entry 418
- Source record ID
prohibited:418- Source version
- Health Canada Hotlist 2025-08-13
- Source language
- English
- Translation status
- Original is English
- Source updated
- 2025-08-13
- Snapshot checked
- 2026-08-30 04:07 UTC
- Validation method
- strict HTML tables t1=490 and t2=90
- SHA-256
8b52ff573d08373ee90121f6a701b3607e4a3d6fc748a7d56171eb53510af91a
Registered dataset notes
- Dataset coverage
- Administrative prohibitions, restrictions, conditions and warning requirements
- Authority note
- Official Health Canada compliance indicator; not a complete safety clearance
How this record fits the market dataset
Status distribution
Condition text is present on 172 of 580 current records. An empty condition field is interpreted according to the record type above; it is never converted into an unrestricted-use claim.
Canada market context
Complete Hotlist snapshot
Coverage version: Health Canada Cosmetic Ingredient Hotlist, 13 August 2025
All prohibited and restricted Hotlist entries, including conditions and warning requirements published in the official list.
Verification checklist
- Search English/French names and CAS identifiers.
- Apply every restriction, concentration and label warning.
- Check Food and Drugs Act/Cosmetic Regulations requirements.
- Recheck the current Hotlist before notification or sale.
Official market sources
- Health Canada Cosmetic Ingredient HotlistOfficial Health Canada compliance indicator; not a complete safety clearance
Verification workflow and record completeness
Before using this result in a compliance decision
- Confirm that “Solvent Red 49:1” and every CAS/EC identifier refer to the material in your supplier specification.
- Search English/French names and CAS identifiers.
- Apply every restriction, concentration and label warning.
- Check Food and Drugs Act/Cosmetic Regulations requirements.
- Recheck the current Hotlist before notification or sale.
- Document the source version and recheck the regulator before manufacture, notification or market placement.
Fields available in this record
- Official substance nameAvailable
- CASAvailable
- ECAvailable
- Separate condition textAvailable
- Effective dateNot supplied
- Snapshot hash and methodAvailable
Questions this page answers
Stable citation
Solvent Red 49:1. Hotlist prohibited entry 418. Canada. Source version Health Canada Hotlist 2025-08-13. CosIng Checker regulatory record: https://cosingchecker.com/regulations/ca/records/418/
Cite the regulator as the legal authority. This page is a structured evidence index and verification aid, not a substitute for the official text or professional legal assessment.
Interpretation and limits for Canada
This official record identifies the substance as prohibited for cosmetic use in the stated market scope.
Do not rely on a formulation containing this identity until the cited source, effective date and exact substance match have been verified.
How to interpret the legal role
The authority uses this source as compliance guidance; the underlying legislation remains controlling.
Evidence on this page
- Recorded outcome: Prohibited
- Legal role: Official guidance
- Source version: Health Canada Hotlist 2025-08-13
What it does not prove
The Hotlist is an administrative compliance tool, not an exhaustive safety approval list.
Further authoritative substance research
These sources can add identity, safety, exposure or hazard context. A link is not evidence that the database contains this exact substance, and none of these sources overrides the market decision above.
Cosmetic Ingredient Review safety assessments
Expert Panel conclusions, assessed ingredient groups, use conditions, dates and report documents
Independent expert review considered by FDA; not a government approval or binding market rule
Research this identity at the sourceFDA Global Substance Registration System
UNII identifiers, preferred names, substance types, codes and public substance relationships
Identity registry only; UNII availability does not imply FDA review or approval
Research this identity at the sourceILO/WHO International Chemical Safety Cards
Hazards, symptoms, first aid, storage, incompatibilities and physical properties for covered chemicals
International occupational chemical-safety reference; not cosmetic-use approval
Research this identity at the sourceJapan NITE-CHRIP
Chemical identity, Japanese and foreign legal lists, GHS hazards and exposure-related information
Chemical-management evidence; cosmetic status remains governed by the applicable MHLW standard and market rules
Research this identity at the sourceNIOSH Pocket Guide to Chemical Hazards
REL, PEL, IDLH, properties, exposure routes, symptoms, target organs, first aid and measurement methods for covered workplace chemicals
US occupational-health guidance and limits; not a cosmetic ingredient decision
Research this identity at the sourceOECD eChemPortal
Gateway to authority-owned physical-property, fate, ecotoxicity, toxicity, exposure and GHS records
Discovery gateway; each linked authority remains responsible for its data
Research this identity at the sourceUS EPA CompTox CTX APIs
API key required for importDTXSID identity, experimental and predicted properties, toxicity, bioactivity, exposure and environmental data
Scientific and computational evidence; predictions must remain labelled and do not determine cosmetic legality
Research this identity at the source