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RestrictedBinding ruleAUOriginal is EnglishOfficial-source import checked

TRANEXAMIC ACID

The current Australian Poisons Standard places this cosmetic or personal-care use in Schedule 4.

All Australia recordsOpen ingredient profileCompare all marketsOpen official source

Regulatory decision and full conditions

Status
Restricted
Legal role
Binding rule
Regulatory summary
The current Australian Poisons Standard places this cosmetic or personal-care use in Schedule 4.
Conditions and restrictions
TRANEXAMIC ACID except in preparations containing 3% or less of tranexamic acid for dermal cosmetic use.

Substance identity

Official source name
TRANEXAMIC ACID
CAS
1197-18-8
EC
214-818-2
Identity mapping
exact_name
Linked ingredient
TRANEXAMIC ACID
Search this identity across the siteCAS 1197-18-8EC 214-818-2

Linked CosIng identity data

Names and aliases

TRANEXAMIC ACID

CosIng description: Cyclohexanecarboxylic acid, 4-(aminomethyl)-, trans-

Recorded cosmetic function: ASTRINGENT, SKIN CONDITIONING

Function pages:ASTRINGENT, SKIN CONDITIONING

View the complete ingredient profile

Cross-market snapshot for this identity

Exact linked records currently present in this site. An absent market means no imported exact match, not permission to use the substance.

2 market datasets
PubChem 2D chemical structure for CAS 1197-18-8
CAS 1197-18-8PubChem CID 5526

Verified chemistry for CAS 1197-18-8

4-(Aminomethyl)cyclohexanecarboxylic acid

IUPAC name
4-(aminomethyl)cyclohexane-1-carboxylic acid
Molecular formula
C8H15NO2
Molecular weight
157.21 g/mol
Exact mass
157.110278721 Da
Monoisotopic mass
157.110278721 Da
XLogP3
-2.0
Topological polar surface area
63.3 Ų
Molecular complexity
139.0
Formal charge
0
Hydrogen-bond donors
2
Hydrogen-bond acceptors
3
Rotatable bonds
2
Heavy atoms
11
Covalent units
1

Names and synonyms reported to PubChem

701-54-2Cyclohexanecarboxylic acid, 4-(aminomethyl)-4-(Aminomethyl)-Cyclohexanecarboxylic AcidRefChem:1070026622-133-9tranexamic acid1197-17-7trans-4-(Aminomethyl)cyclohexanecarboxylic acid
16 more reported names
CyklokapronTrans AMCHACyclocapronTransaminAmstatTranhexamic acidTranexamsaeureRikavarintrans-AmchaAmikapronAnvitoffcis-Tranexamic AcidUgurolcis-4-(Aminomethyl)cyclohexanecarboxylic acidFrenolyseTranexan
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D pharmacophore features
6
3D rings
1
3D hydrophobes
0
3D acceptor features
2
3D donor features
1
3D anionic centres
1
3D cationic centres
1
3D conformers
10
Effective 3D rotors
3.2
Machine-readable structure identifiers
SMILES
C1CC(CCC1CN)C(=O)O
InChI
InChI=1S/C8H15NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h6-7H,1-5,9H2,(H,10,11)
InChIKey
GYDJEQRTZSCIOI-UHFFFAOYSA-N

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match5526

Attributed physical-property, hazard, environmental and use annotations.

  • Signal: Warning Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P264+P265, P280, P305+P351+P338, and P337+P317 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 39 reports by companies from 1 notifications to the ECHA C&L Inventory.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Official source and provenance

Registered source
Australia Poisons Standard (SUSMP)
Source reference
Therapeutic Goods (Poisons Standard—June 2026) Instrument 2026, Schedule 4
Source record ID
schedule-4:tranexamic-acid:10
Source version
Therapeutic Goods (Poisons Standard—June 2026) Instrument 2026
Source language
English
Translation status
Original is English
Effective date
2026-06-01
Source updated
2026-05-28
Snapshot checked
2026-08-31 15:26 UTC
Validation method
pdftotext -layout; 674 pages; exact cosmetic-relevant per-schedule counts {2: 4, 4: 12, 5: 15, 6: 62, 10: 32}
SHA-256
38478bdefd4ebaf571ac39001e2ce35026a7edafbaec995e75746ce69a650e11

Registered dataset notes

Dataset coverage
All current Poisons Standard entries whose source wording explicitly covers cosmetics or personal-care uses
Authority note
Binding Commonwealth scheduling instrument; state and territory implementation and AICIS duties still apply
Inspect the exact official sourceRegulator guidance

How this record fits the market dataset

125
current Australia records
93
records marked Restricted
125
records from this source version
41
market records with CAS identity

Status distribution

Prohibited: 32Restricted: 93

Condition text is present on 125 of 125 current records. An empty condition field is interpreted according to the record type above; it is never converted into an unrestricted-use claim.

Australia market context

Complete cosmetic-relevant Poisons Standard subset plus official workflow

Coverage version: Therapeutic Goods (Poisons Standard—June 2026) Instrument 2026

All 125 current Schedule 2, 4, 5, 6 and 10 entries whose legal wording explicitly covers cosmetics or personal-care uses, plus AICIS verification links.

Verification checklist

  1. Decide whether the product is a cosmetic or therapeutic good.
  2. Check the current Poisons Standard for every ingredient.
  3. Search AICIS Inventory terms and assessment certificates by exact identity.
  4. Determine introduction category, registration, reporting, records and labelling duties.

Official market sources

Verification workflow and record completeness

Before using this result in a compliance decision

  1. Confirm that “TRANEXAMIC ACID” and every CAS/EC identifier refer to the material in your supplier specification.
  2. Decide whether the product is a cosmetic or therapeutic good.
  3. Check the current Poisons Standard for every ingredient.
  4. Search AICIS Inventory terms and assessment certificates by exact identity.
  5. Determine introduction category, registration, reporting, records and labelling duties.
  6. Document the source version and recheck the regulator before manufacture, notification or market placement.

Fields available in this record

  • Official substance nameAvailable
  • CASAvailable
  • ECAvailable
  • Separate condition textAvailable
  • Effective dateAvailable
  • Snapshot hash and methodAvailable

Questions this page answers

This substance is not unrestricted: cosmetic use is subject to the conditions in the cited official record. Check product type, body area, concentration, purity and warning requirements before deciding whether a formulation is compliant.

If this row does not reproduce conditions, open the cited official detail because omission does not mean unrestricted use. An AICIS Inventory match is not cosmetic approval; no Inventory match can indicate a new, exempted, reported or confidential introduction.

The record cites Therapeutic Goods (Poisons Standard—June 2026) Instrument 2026, Schedule 4, source version Therapeutic Goods (Poisons Standard—June 2026) Instrument 2026. Open the official source.

No. CAS helps resolve identity, but jurisdictions can classify the same substance differently and can apply different product scopes, limits, warnings and transition dates.

Stable citation

TRANEXAMIC ACID. Therapeutic Goods (Poisons Standard—June 2026) Instrument 2026, Schedule 4. Australia. Source version Therapeutic Goods (Poisons Standard—June 2026) Instrument 2026. CosIng Checker regulatory record: https://cosingchecker.com/regulations/au/records/13096/

Cite the regulator as the legal authority. This page is a structured evidence index and verification aid, not a substitute for the official text or professional legal assessment.

Interpretation and limits for Australia

This substance is not unrestricted: cosmetic use is subject to the conditions in the cited official record.

Check product type, body area, concentration, purity and warning requirements before deciding whether a formulation is compliant.

How to interpret the legal role

The cited row forms part of a binding rule or legally incorporated list for this market.

Evidence on this page

  • Recorded outcome: Restricted
  • Legal role: Binding rule
  • Source version: Therapeutic Goods (Poisons Standard—June 2026) Instrument 2026
  • Effective date: 2026-06-01

What it does not prove

An AICIS Inventory match is not cosmetic approval; no Inventory match can indicate a new, exempted, reported or confidential introduction.

Further authoritative substance research

These sources can add identity, safety, exposure or hazard context. A link is not evidence that the database contains this exact substance, and none of these sources overrides the market decision above.

Cosmetic Ingredient Review safety assessments

Expert Panel conclusions, assessed ingredient groups, use conditions, dates and report documents

Independent expert review considered by FDA; not a government approval or binding market rule

Research this identity at the source

FDA Global Substance Registration System

UNII identifiers, preferred names, substance types, codes and public substance relationships

Identity registry only; UNII availability does not imply FDA review or approval

Research this identity at the source

ILO/WHO International Chemical Safety Cards

Hazards, symptoms, first aid, storage, incompatibilities and physical properties for covered chemicals

International occupational chemical-safety reference; not cosmetic-use approval

Research this identity at the source

Japan NITE-CHRIP

Chemical identity, Japanese and foreign legal lists, GHS hazards and exposure-related information

Chemical-management evidence; cosmetic status remains governed by the applicable MHLW standard and market rules

Research this identity at the source

NIOSH Pocket Guide to Chemical Hazards

REL, PEL, IDLH, properties, exposure routes, symptoms, target organs, first aid and measurement methods for covered workplace chemicals

US occupational-health guidance and limits; not a cosmetic ingredient decision

Research this identity at the source

OECD eChemPortal

Gateway to authority-owned physical-property, fate, ecotoxicity, toxicity, exposure and GHS records

Discovery gateway; each linked authority remains responsible for its data

Research this identity at the source

US EPA CompTox CTX APIs

API key required for import

DTXSID identity, experimental and predicted properties, toxicity, bioactivity, exposure and environmental data

Scientific and computational evidence; predictions must remain labelled and do not determine cosmetic legality

Research this identity at the source