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Glutaraldehyde (Pentane-1,5-dial) CAS No. 111-30-8

ASEAN Annex VI lists this record among preservatives allowed for cosmetic use. Member-state transition rules and deviations still require local verification.

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Regulatory decision and full conditions

Status
Permitted list with conditions
Legal role
Binding rule
Regulatory summary
ASEAN Annex VI lists this record among preservatives allowed for cosmetic use. Member-state transition rules and deviations still require local verification.
Conditions and restrictions
0.1% · Prohibited in aerosols (sprays) · - Contains glutaraldehyde (where glutaraldehyde concentration in the finished product exceeds 0.05%)

Substance identity

Official source name
Glutaraldehyde (Pentane-1,5-dial) CAS No. 111-30-8
CAS
111-30-8
EC
203-856-5
Identity mapping
cas_number
Linked ingredient
GLUTARAL
Search this identity across the siteCAS 111-30-8EC 203-856-5

Linked CosIng identity data

Names and aliases

GLUTARALglutaral

CosIng description: Pentanedial

EU inventory restriction note: V/48

Recorded cosmetic function: FRAGRANCE, PRESERVATIVE

Function pages:FRAGRANCE, PRESERVATIVE

View the complete ingredient profile

Cross-market snapshot for this identity

Exact linked records currently present in this site. An absent market means no imported exact match, not permission to use the substance.

5 market datasets

European Union

Positive-list entry with conditions

1 linked record · 1 with specific conditions

Open supporting record

Great Britain

Permitted list with conditions

1 linked record · 1 with specific conditions

Open supporting record

ASEAN

Current record
Permitted list with conditions

1 linked record · 1 with specific conditions

Open supporting record
PubChem 2D chemical structure for CAS 111-30-8
CAS 111-30-8PubChem CID 3485

Verified chemistry for CAS 111-30-8

Glutaraldehyde

IUPAC name
pentanedial
Molecular formula
C5H8O2
Molecular weight
100.12 g/mol
Exact mass
100.052429494 Da
Monoisotopic mass
100.052429494 Da
XLogP3
-0.5
Topological polar surface area
34.1 Ų
Molecular complexity
51.0
Formal charge
0
Hydrogen-bond donors
0
Hydrogen-bond acceptors
2
Rotatable bonds
4
Heavy atoms
7
Covalent units
1

Names and synonyms reported to PubChem

GlutaralGlutaric dialdehyde1,5-PentanedialSonacideGlutardialdehydeAlhydexGlutaric acid dialdehydeGlutaric aldehyde
16 more reported names
GlutaraldehydGlutaralumAldesanUcarcideHospex1,5-Pentanedione1,3-DiformylpropaneAldesenSterihyde LSterihydeAldehyd glutarowyCidex 7GlutacleanVerucasepNCI-C55425Relugan GT
Open full PubChem recordSafety and hazards at PubChemPubChem annotationsChemical classifications3D structure image
External database identifiers
Advanced structure statistics
Defined atom stereocentres
0
Undefined atom stereocentres
0
Defined bond stereocentres
0
Undefined bond stereocentres
0
3D pharmacophore features
2
3D rings
0
3D hydrophobes
0
3D acceptor features
2
3D donor features
0
3D anionic centres
0
3D cationic centres
0
3D conformers
10
Effective 3D rotors
4.0
Machine-readable structure identifiers
SMILES
C(CC=O)CC=O
InChI
InChI=1S/C5H8O2/c6-4-2-1-3-5-7/h4-5H,1-3H2
InChIKey
SXRSQZLOMIGNAQ-UHFFFAOYSA-N

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match3485

Attributed physical-property, hazard, environmental and use annotations.

  • Substance: Glutaraldehyde Source: NTP Technical Reports
  • NTP Technical Report: TR-490: Toxicology and Carcinogenesis Studies of Glutaraldehyde (CASRN 111-30-8) in F344/N Rats and B6C3F1 Mice (Inhalation Studies) (1999 ) Source: NTP Technical Reports
  • Peer Review Date: 10/30/98 Source: NTP Technical Reports
  • Conclusion for Male Rat: No Evidence Source: NTP Technical Reports
  • Conclusion for Female Rat: No Evidence Source: NTP Technical Reports
  • Conclusion for Male Mice: No Evidence Source: NTP Technical Reports
  • Conclusion for Female Mice: No Evidence Source: NTP Technical Reports
  • Summary: Under the conditions of these 2-year inhalation studies, there was no evidence of carcinogenic activity of glutaraldehyde in male or female F344/N rats exposed to 250, 500, or 750 ppb. There was no evidence of carcinogenic activity in male or female B6C3F1 mice exposed to 62.5, 125, or 250 ppb.; Incidences of nonneoplastic lesions of the nose were significantly increased in male and female rats and mice. Source: NTP Technical Reports
  • Carcinogen Classification: No indication of carcinogenicity to humans (not listed by IARC). Source: Toxin and Toxin Target Database (T3DB)
  • First Aid: EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.; SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.; INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) shou Source: CAMEO Chemicals
  • First Aid: (General first aid procedures); Eye: Irrigate immediately - If this chemical contacts the eyes, immediately wash (irrigate) the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately.; Skin: Water flush immediately - If this chemical contacts the skin, immediately flush the contaminated skin with water. If this chemical penetrates the clothing, immediately remove the clothing and flush the skin with water. Get medical attention promptly.; Breathing: Respiratory support; Swallow: Medical attention immediately - If this chemical has been swallowed, get medical attention immediately. Source: The National Institute for Occupational Safety and Health (NIOSH)
  • Signal: Danger Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • GHS Hazard Statements: H301: Toxic if swallowed [Danger Acute toxicity, oral]; H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]; H317: May cause an allergic skin reaction [Warning Sensitization, Skin]; H330: Fatal if inhaled [Danger Acute toxicity, inhalation]; H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory]; H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]; H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]; H411: Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Precautionary Statement Codes: P233, P260, P261, P264, P270, P271, P272, P273, P280, P284, P301+P316, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P319, P320, P321, P330, P333+P317, P342+P316, P362+P364, P363, P391, P403, P403+P233, P405, and P501 (click each P-code to see the statement) Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Note: This chemical does not meet GHS hazard criteria for < 0.1% (1 of 2123) of reports. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H301 (> 99.9%): Toxic if swallowed [Danger Acute toxicity, oral]; H314 (> 99.9%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]; H317 (> 99.9%): May cause an allergic skin reaction [Warning Sensitization, Skin]; H318 (18.7%): Causes serious eye damage [Danger Serious eye damage/eye irritation]; H330 (20.1%): Fatal if inhaled [Danger Acute toxicity, inhalation]; H331 (82.6%): Toxic if inhaled [Danger Acute toxicity, inhalation]; H334 (> 99.9%): May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory]; H335 (19%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]; H400 (99.9%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]; H411 (16.1%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P233, P260, P261, P264, P264+P265, P270, P271, P272, P273, P280, P284, P301+P316, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P319, P320, P321, P330, P333+P317, P342+P316, P362+P364, P363, P391, P403, P403+P233, P405, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 2123 reports by companies from 44 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Reported as not meeting GHS hazard criteria per 1 of 2123 reports by companies.; There are 43 notifications provided by 2122 of 2123 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Signal: Danger Source: NITE-CMC
  • GHS Hazard Statements: H227: Combustible liquid [Warning Flammable liquids]; H301: Toxic if swallowed [Danger Acute toxicity, oral]; H311: Toxic in contact with skin [Danger Acute toxicity, dermal]; H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]; H317: May cause an allergic skin reaction [Warning Sensitization, Skin]; H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]; H330: Fatal if inhaled [Danger Acute toxicity, inhalation]; H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory]; H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]; H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]; H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]; H411: Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] Source: NITE-CMC
  • Precautionary Statement Codes: P210, P233, P260, P261, P262, P264, P264+P265, P270, P271, P272, P273, P280, P284, P301+P316, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P308+P316, P316, P317, P319, P320, P321, P330, P333+P317, P342+P316, P361+P364, P362+P364, P363, P370+P378, P391, P403, P403+P233, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
  • GHS Hazard Statements: H227: Combustible liquid [Warning Flammable liquids]; H301: Toxic if swallowed [Danger Acute toxicity, oral]; H312: Harmful in contact with skin [Warning Acute toxicity, dermal]; H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]; H317: May cause an allergic skin reaction [Warning Sensitization, Skin]; H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]; H330: Fatal if inhaled [Danger Acute toxicity, inhalation]; H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory]; H335: May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]; H370: Causes damage to organs [Danger Specific target organ toxicity, single exposure]; H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure] Source: NITE-CMC
  • Cosmetic Ingredient Review Conclusion: Based upon the animal and clinical data presented in this report, the CIR Expert Panel concludes that Glutaral is safe for use at concentrations up to 0.5% in rinse-off products. There is insufficient data to determine the safety of Glutaral in leave-on products. Glutaral should not be used in aerosolized products. Source: Cosmetic Ingredient Review (CIR)
  • Cosmetic Ingredient Review Finding(s): Safe for use in cosmetics, with qualifications Source: Cosmetic Ingredient Review (CIR)
  • Toxicity Summary: IDENTIFICATION AND USE: Glutaraldehyde is a colorless liquid. It is registered for pesticide use in the U.S. but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses. It is used as algaecide, bacteriocide and fungicide. Glutaraldehyde is used as a tissue fixative in histology and electron and light microscopy, generally as a 1.5-6% aqueous solution. Glutaraldehyde is used, generally in conjunction with wetting agents, to control viruses and other micro-organisms in fish farming. Glutaraldehyde is allowed as a preservative in cosmetics in Europe at concentrations up to 0.1%. It is not allowed in aerosols and sprays. Glutaraldehyde is a biocide commonly used in a 2% concentration for cold sterilization of surgical and dental equipment. Biocides, such as glutaraldehyde, are added to eliminate bacterial growth in fracturing fluids. HUMAN EXPOSURE AND TOXICITY: Exposure to concentrations < 1 ppm by inhalation or skin contact may cause irritation of the skin and/or mucous membranes. The critical effects of glutaraldehyde exposure are eye, skin, and respiratory irritation, skin sensitization and occupatio Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Bioconcentration: An estimated BCF of 3 was calculated for glutaraldehyde(SRC), using a log Kow of -0.33(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: TERRESTRIAL FATE: Based on a classification scheme(1), measured Koc values ranging from 5.1 to 500(2,3) indicate that glutaraldehyde is expected to have very high to moderate mobility in soil(SRC). Volatilization of glutaraldehyde from moist soil surfaces is not expected to be an important fate process(SRC) given a Henry's Law constant of 3.3X10-8 atm-cu m/mole(2). Glutaraldehyde is expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 0.6 mm Hg at 30 °C(4), and it has been reported that small amounts of glutaraldehyde will volatilize to the atmosphere(4). Results of biodegradation screening tests indicate that glutaraldehyde is readily biodegradable(2,3,5). A soil degradation study using a loamy sand soil and and initial glutaraldehyde concentration of 10 ppm observed a pseudo-first order dissipation half-life of 1.7 days due primarily to soil microorganisms(3). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: AQUATIC FATE: Based on a classification scheme(1), measured Koc values ranging from 5.1 to 500(2,3) indicate that glutaraldehyde is not expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is not expected(4) based upon a Henry's Law constant of 3.3X10-8 atm-cu m/mole(2). According to a classification scheme(5), an estimated BCF of 3(SRC), from its log Kow of -0.33(2) and a regression-derived equation(6), suggests the potential for bioconcentration in aquatic organisms is low(SRC). Results of biodegradation screening tests indicate that glutaraldehyde is readily biodegradable(2,3,7). In a closed bottle test using seawater as inoculum, glutaraldehyde showed 73% degradation in 28 days(2). At 25 °C, glutaraldehyde has measured hydrolysis half-lives of 508-628, 102-394 and 46-63.8 days at pH 5, pH 7 and pH 9 respectively(2,3). The measured half-life for the photolysis of sterile aqueous solutions of glutaraldehyde exposed to natural sunlight was 196 days(2). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), glutaraldehyde, which has a vapor pressure of 0.6 mm Hg at 30 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase glutaraldehyde is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 15 hours(SRC), calculated from its rate constant of 2.52X10-11 cu cm/molecule-sec at 25 °C(3). Aqueous solutions of glutaraldehyde have an observed photolysis half-life of 196 days when exposed to sunlight(4) suggesting that direct photolysis may occur in the ambient atmosphere(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Industry Uses: Other; Tanning agents not otherwise specified; Corrosion inhibitor; Not Known or Reasonably Ascertainable; Embalming agent; Preservative; Intermediate; Processing aids, specific to petroleum production Source: EPA Chemical Data Reporting (CDR)
  • Cosmetic Ingredient Review Link: CIR ingredient: Glutaral Source: Cosmetic Ingredient Review (CIR)
  • Sources/Uses: Glutaraldehyde is used in hospitals and medical and dental offices in solutions for cold sterilization and automatic processing of x-rays. [Marks, p. 146-7] Used as a tissue fixative in histology and microscopy, chemical intermediate, embalming fluid, biocide (cosmetics, water treatment, oilfield, and fish farming applications), disinfectant, cross-linking agent, leather tanning agent, gelatine hardening agent, and keratolytic; [HSDB] Used as an antimicrobial agent in agricultural, food handling, commercial, industrial, residential, public, and medical environments; Also used as materials preservative (cleansers, adhesives, paper, water based coatings, latex paints, inks, dyes, concrete admixtures, and reverse osmosis membranes) and in industrial processes and water systems treatment (recirculating and waste-water water systems, drilling muds, oil and gas storage systems, paper mills, and metalworking fluids); [Reference #1] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Industrial Processes with risk of exposure: Metal Machining [Category: Heat or Machine]; Petroleum Production and Refining [Category: Industry]; Pulp and Paper Processing [Category: Industry]; Painting (Pigments, Binders, and Biocides) [Category: Paint]; Using Disinfectants or Biocides [Category: Clean]; Sterilizing Equipment [Category: Clean]; Sewer and Wastewater Treatment [Category: Industry]; Leather Tanning and Processing [Category: Industry]; Photographic Processing [Category: Other]; Farming (Respiratory Hazards) [Category: Industry] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Uses: For glutaraldehyde (USEPA/OPP Pesticide Code: 043901) ACTIVE products with label matches. /SRP: Registered for use in the U.S. but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses./ Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Microscopy/histology. Glutaraldehyde is used as a tissue fixative in histology and electron and light microscopy, generally as a 1.5-6% aqueous solution. Aquaculture. Glutaraldehyde is used, generally in conjunction with wetting agents, to control viruses and other micro-organisms in fish farming. Cosmetics. Glutaraldehyde is allowed as a preservative in cosmetics in Europe at concentrations up to 0.1%. It is not allowed in aerosols and sprays. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Embalming fluid Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Intermediate; fixative for tissues; cross-linking protein and polyhydroxy materials, tanning of soft leathers. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: For more Uses (Complete) data for Glutaraldehyde (16 total), please visit the HSDB record page. Source: Hazardous Substances Data Bank (HSDB)
  • Uses: Use (kg; approx.) in Germany (2009): >25000; Use (kg; exact) in Germany (2009): 47964; Consumption (g per capita; approx.) in Germany (2009): 0.305; Consumption (g per capita; exact) in Germany (2009): 0.586; Calculated removal (%): 92.1 Source: NORMAN Suspect List Exchange
  • Uses: Glutaral is used as an antimicrobial agent in sugar mills and as a fixing agent in the immobilisation of glucose isomerase enzyme preparations for use in the manufacture of high fructose corn syrup A polymerized isomer of glutaraldehyde known as polycycloglutaracetal is a fertilizer for aquatic plants. Glutaraldehyde is a colorless liquid with a pungent odor used to disinfect medical and dental equipment. It is also used for industrial water treatment and as a chemical preservative. It is used as a tissue fixative in electron microscopy. Glutaraldehyde is frequently used in biochemistry applications as an amine-reactive homobifunctional crosslinker. Source: Toxin and Toxin Target Database (T3DB)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Official source and provenance

Registered source
ASEAN Cosmetic Directive annexes
Source reference
ASEAN Annex VI, reference 48
Source record ID
VI-48
Source version
2026-1
Source language
English
Translation status
Original is English
Source updated
2026-06-22
Snapshot checked
2026-08-30 04:44 UTC
Validation method
pdfplumber ruled-table extraction with per-annex reviewed counts
SHA-256
ffad59f6c01a92c82042c54203ee14969425c2a82bd04c2f4012ff82513e69f1

Registered dataset notes

Dataset coverage
Banned, restricted and positive-list substances under the harmonised ASEAN framework
Authority note
Regional directive; member-state transitions and deviations still require local verification
Inspect the exact official sourceRegulator guidance

How this record fits the market dataset

2224
current ASEAN records
247
records marked Permitted list with conditions
2224
records from this source version
1930
market records with CAS identity

Status distribution

Permitted list with conditions: 247Prohibited: 1728Restricted: 249

Condition text is present on 462 of 2224 current records. An empty condition field is interpreted according to the record type above; it is never converted into an unrestricted-use claim.

ASEAN market context

Complete regional annex dataset

Coverage version: ASEAN Cosmetic Directive annexes 2026-1, 22 June 2026

Annexes II, III, IV, VI and VII covering prohibited, restricted and positive-list substances.

Verification checklist

  1. Search all ACD annexes by name and identifiers.
  2. Apply product type, maximum level and warning conditions.
  3. Confirm the target member state's adoption and transition date.
  4. Complete the local notification and responsible-company requirements.

Official market sources

Verification workflow and record completeness

Before using this result in a compliance decision

  1. Confirm that “Glutaraldehyde (Pentane-1,5-dial) CAS No. 111-30-8” and every CAS/EC identifier refer to the material in your supplier specification.
  2. Search all ACD annexes by name and identifiers.
  3. Apply product type, maximum level and warning conditions.
  4. Confirm the target member state's adoption and transition date.
  5. Complete the local notification and responsible-company requirements.
  6. Document the source version and recheck the regulator before manufacture, notification or market placement.

Fields available in this record

  • Official substance nameAvailable
  • CASAvailable
  • ECAvailable
  • Separate condition textAvailable
  • Effective dateNot supplied
  • Snapshot hash and methodAvailable

Questions this page answers

This identity appears on a market positive list for the list function represented by the source record. Confirm that the intended function and product use fall within the list scope and every stated condition.

Positive-list presence is purpose-specific and is not blanket approval for every cosmetic use. Regional annex coverage does not replace member-state implementation dates, notifications or national deviations.

The record cites ASEAN Annex VI, reference 48, source version 2026-1. Open the official source.

No. CAS helps resolve identity, but jurisdictions can classify the same substance differently and can apply different product scopes, limits, warnings and transition dates.

Stable citation

Glutaraldehyde (Pentane-1,5-dial) CAS No. 111-30-8. ASEAN Annex VI, reference 48. ASEAN. Source version 2026-1. CosIng Checker regulatory record: https://cosingchecker.com/regulations/asean/records/4307/

Cite the regulator as the legal authority. This page is a structured evidence index and verification aid, not a substitute for the official text or professional legal assessment.

Interpretation and limits for ASEAN

This identity appears on a market positive list for the list function represented by the source record.

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How to interpret the legal role

The cited row forms part of a binding rule or legally incorporated list for this market.

Evidence on this page

  • Recorded outcome: Permitted list with conditions
  • Legal role: Binding rule
  • Source version: 2026-1

What it does not prove

Regional annex coverage does not replace member-state implementation dates, notifications or national deviations.

Further authoritative substance research

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Cosmetic Ingredient Review safety assessments

Expert Panel conclusions, assessed ingredient groups, use conditions, dates and report documents

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FDA Global Substance Registration System

UNII identifiers, preferred names, substance types, codes and public substance relationships

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ILO/WHO International Chemical Safety Cards

Hazards, symptoms, first aid, storage, incompatibilities and physical properties for covered chemicals

International occupational chemical-safety reference; not cosmetic-use approval

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Japan NITE-CHRIP

Chemical identity, Japanese and foreign legal lists, GHS hazards and exposure-related information

Chemical-management evidence; cosmetic status remains governed by the applicable MHLW standard and market rules

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NIOSH Pocket Guide to Chemical Hazards

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OECD eChemPortal

Gateway to authority-owned physical-property, fate, ecotoxicity, toxicity, exposure and GHS records

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US EPA CompTox CTX APIs

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DTXSID identity, experimental and predicted properties, toxicity, bioactivity, exposure and environmental data

Scientific and computational evidence; predictions must remain labelled and do not determine cosmetic legality

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