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CAS 62218-13-7 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef cosing-live-988842023-05-23

ALPHA-VINIFERIN

Alpha-Viniferin is the organic compound that conforms to the formula:

ALPHA-VINIFERIN is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 62218-13-7

CAS 62218-13-7PubChem CID 196402

Alpha-Viniferin

(+)-alpha-viniferin is a nine-membered macrocycle that incorporates three 6-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-1-benzofuranyl moieties as part of the cyclic skeleton. It is isolated from Caragana chamlague Lamarck and exhibits significant inhibitory effect towards the enzyme acetylcholinesterase (EC 3.1.1.7). It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor, an anti-inflammatory agent and a plant metabolite. It is a polyphenol, a member of 1-benzofurans and a macrocycle. It is functionally related to a resveratrol. — ChEBI

IUPAC name: (2R,3R,10R,11R,18S,19S)-3,11,19-tris(4-hydroxyphenyl)-4,12,20-trioxaheptacyclo[16.6.1.12,5.110,13.021,25.09,27.017,26]heptacosa-1(25),5,7,9(27),13,15,17(26),21,23-nonaene-7,15,23-triol

Molecular formula: C42H30O9
Molecular weight: 678.7 g/mol
Exact mass: 678.18898253 Da
XLogP3: 6.8
Topological polar surface area: 149.0 Å²
Hydrogen-bond donors: 6
Hydrogen-bond acceptors: 9
Covalent units: 1
Defined stereocentres: 6

Also known as

(+)-Alpha-Viniferin53XER6FHLXCHEBI:66359RefChem:1114023,11,19-tris(4-hydroxyphenyl)-4,12,20-trioxaheptacyclo(16.6.1.12,5.110,13.021,25.09,27.017,26)heptacosa-1(25),5,7,9(27),13,15,17(26),21,23-nonaene-7,15,23-triol(+)-.alpha.-Viniferin(+)--ViniferinViniferin-alpha

12 more reported names

+/--Viniferin| cent-ViniferinUNII-53XER6FHLX.ALPHA.-VINIFERINVINIFERIN, ALPHA-(+)-| cent-ViniferinHY-N2854TN1378FS-8889CS-00234323'',4'':7,8,9]cyclonona[1,2,3-cd][1]benzofuran-4,9,14-triol(2R,2aR,7R,7aR,12S,12aS)-2,7,12-tris(4-hydroxyphenyl)-2,2a,7,7a,12,12a-hexahydrobis[1]benzofuro[3',4':4,5,6

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:66359
ChEMBL:CHEMBL443463
EPA DTXSID:DTXSID40211274
PubMed:24859013
PubMed:22584350
PubMed:20424383
PubMed:16827148
PubMed:16158945
PubMed:14531020

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Official European Commission record

CosIng substance ID: 98884
Entry status: Active
Published in the Official Journal: Yes
Recorded by the Commission: 2023-05-23

Open this entry in the official CosIng database

Fields as published by the European Commission. The link opens the entry itself, not a search for it.

Inventory details for ALPHA-VINIFERIN

INCI name

ALPHA-VINIFERIN

Description

Alpha-Viniferin is the organic compound that conforms to the formula:

Record provenance

Inventory reference: cosing-live-98884
Imported identity: ALPHA-VINIFERIN
Source update: 2023-05-23

European Commission CosIng source notes

Annex records for ALPHA-VINIFERIN

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Key data

CAS

62218-13-7

—

Restriction

—

Function

UV FILTER: Exclusively or mainly intended to protect the skin and/or hair against certain UV radiation by absorbing, reflecting or scattering UV radiation. All authorised UV filters are substances in the positive list of Annex VI to the Cosmetics Regulation 1223/2009.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#1480 · ALPHA-VINIFERIN

Ingredients with overlapping formulation functions

4-(2-BETA-GLUCOPYRANOSILOXY) PROPOXY-2HYDROXYBENZOPHENONELIGHT STABILIZER, UV FILTER

4-METHYLBENZYLIDENE CAMPHORLIGHT STABILIZER, UV ABSORBER, UV FILTER

7-DEHYDROCHOLESTERYL PALMITATESKIN PROTECTING, UV FILTER

ASTER YOMENA EXTRACTSKIN CONDITIONING, SOLVENT, SURFACE MODIFIER, UV FILTER

BACILLUS LYSATESKIN PROTECTING, UV FILTER

BENZOPHENONE-3LIGHT STABILIZER, UV ABSORBER, UV FILTER

BENZOPHENONE-4LIGHT STABILIZER, UV ABSORBER, UV FILTER

BENZOPHENONE-5LIGHT STABILIZER, UV ABSORBER, UV FILTER

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How ALPHA-VINIFERIN appears in the CosIng inventory

The CosIng inventory lists ALPHA-VINIFERIN as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

ALPHA-VINIFERIN is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

ALPHA-VINIFERIN is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, ALPHA-VINIFERIN carries the following function designation(s):

UV FILTER

CAS 62218-13-7 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for ALPHA-VINIFERIN

This page reproduces the CosIng inventory entry for ALPHA-VINIFERIN from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research ALPHA-VINIFERIN and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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