What other records share CAS 503-66-2?

CAS 503-66-2 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef cosing-live-1021212024-06-25

3-HYDROXYPROPIONIC ACID

3-Hydroxypropionic Acid is the organic acid that conforms to the formula:

3-HYDROXYPROPIONIC ACID is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 503-66-2

CAS 503-66-2PubChem CID 68152

3-Hydroxypropionic acid

3-hydroxypropionic acid is a 3-hydroxy monocarboxylic acid that is propionic acid in which one of the hydrogens attached to the terminal carbon is replaced by a hydroxy group. It has a role as an Escherichia coli metabolite and a human metabolite. It is an omega-hydroxy-short-chain fatty acid and a 3-hydroxy monocarboxylic acid. It is functionally related to a propionic acid. It is a conjugate acid of a 3-hydroxypropionate. — ChEBI

IUPAC name: 3-hydroxypropanoic acid

Molecular formula: C3H6O3
Molecular weight: 90.08 g/mol
Exact mass: 90.031694049 Da
XLogP3: -1.0
Topological polar surface area: 57.5 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 3
Covalent units: 1
Defined stereocentres: 0

Also known as

Hydracrylic acidbeta-Hydroxypropionic acidhydroxypropionic acidEthylene lactic acidbeta-Lactic acid3-HydroxypropanoateC4ZF6XLD2Xbeta-hydroxypropionate

16 more reported names

CHEBI:33404RefChem:94392207-974-8Propanoic acid, 3-hydroxy-3-HYDROXY-PROPANOIC ACIDEthylenelacticacidGlyceric acid, 2-deoxy-b-HydroxypropionatePropionic acid, 3-hydroxy-3-Hydroxypropionic Acid (contains varying amounts of 3,3-Oxydipropionic Acid)b-Hydroxypropionic acid3-Hydroxypropionic acid, 30% in water.beta.-Hydroxypropionic acid3-Hydroxypropanoic acid30% in waterEthylenelactic acidFamotidine Impurity 13

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:33404
ChEMBL:CHEMBL1205969
EPA DTXSID:DTXSID50198305
PubMed:22923122
PubMed:22886401
PubMed:22803399
PubMed:22715694
PubMed:22710261
PubMed:22684326
PubMed:22675585
PubMed:22675512
PubMed:22666387
PubMed:22649767
PubMed:22649756
PubMed:22615748

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Official European Commission record

CosIng substance ID: 102121
Published in the Official Journal: Yes
Recorded by the Commission: 2024-06-25

Open this entry in the official CosIng database

Fields as published by the European Commission. The link opens the entry itself, not a search for it.

Inventory details for 3-HYDROXYPROPIONIC ACID

INCI name

3-HYDROXYPROPIONIC ACID

Description

3-Hydroxypropionic Acid is the organic acid that conforms to the formula:

Record provenance

Inventory reference: cosing-live-102121
Imported identity: 3-HYDROXYPROPIONIC ACID
Source update: 2024-06-25

European Commission CosIng source notes

Annex records for 3-HYDROXYPROPIONIC ACID

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Key data

CAS

503-66-2

207-974-8

Restriction

—

Function

SKIN CONDITIONING - MISCELLANEOUS: Enhancing the appearance of dry and/or damaged skin by reducing flaking and restoring suppleness.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#287 · 3-HYDROXYPROPIONIC ACID

Ingredients with overlapping formulation functions

2-HYDROXYSTEARIC ACIDHAIR CONDITIONING; SKIN PROTECTING; SURFACTANT - CLEANSING; SKIN CONDITIONING - MISCELLANEOUS

2-MERCAPTONICOTINOYL GLYCINESKIN CONDITIONING - MISCELLANEOUS

2-METHYL-4-HYDROXYPYRROLIDINESKIN CONDITIONING - MISCELLANEOUS

3-ASCORBYLMETHYLCARBONYL GLYCYL TRI-T-BUTYL TRYPTOPHANAMIDEHAIR CONDITIONING; SKIN PROTECTING; SKIN CONDITIONING - MISCELLANEOUS

3-HYDROXYPROPYL SUNFLOWERAMIDESKIN CONDITIONING - EMOLLIENT; SKIN PROTECTING; SKIN CONDITIONING - HUMECTANT; SKIN CONDITIONING - …

4-PCA DIMETHICONEHAIR CONDITIONING; SKIN CONDITIONING - MISCELLANEOUS

4-TOSYLAMIDESKIN CONDITIONING - MISCELLANEOUS

6,8-DIMERCAPTOCAPRYLOYL TRIPEPTIDE-102ANTIOXIDANT; SKIN PROTECTING; SKIN CONDITIONING - MISCELLANEOUS

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How 3-HYDROXYPROPIONIC ACID appears in the CosIng inventory

The CosIng inventory lists 3-HYDROXYPROPIONIC ACID as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

3-HYDROXYPROPIONIC ACID is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

3-HYDROXYPROPIONIC ACID is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, 3-HYDROXYPROPIONIC ACID carries the following function designation(s):

SKIN CONDITIONING - MISCELLANEOUS

CAS 503-66-2 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for 3-HYDROXYPROPIONIC ACID

This page reproduces the CosIng inventory entry for 3-HYDROXYPROPIONIC ACID from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research 3-HYDROXYPROPIONIC ACID and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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