Is PUTRESCINE HCL safe to use in EU cosmetics?

PUTRESCINE HCL is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What other records share CAS 333-93-7?

CAS 333-93-7 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains PUTRESCINE HCL?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef cosing-live-1013642024-07-01

PUTRESCINE HCL

Putrescine HCl is the organic compound that conforms to the formula

PUTRESCINE HCL is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 333-93-7

CAS 333-93-7PubChem CID 9532

Putrescine Dihydrochloride

1,4-Diaminobutane dihydrochloride is an alkylamine. — ChEBI

IUPAC name: butane-1,4-diamine;dihydrochloride

Molecular formula: C4H14Cl2N2
Molecular weight: 161.07 g/mol
Exact mass: 160.0534038 Da
Topological polar surface area: 52.0 Å²
Hydrogen-bond donors: 4
Hydrogen-bond acceptors: 2
Covalent units: 3
Defined stereocentres: 0

Also known as

1,4-Diaminobutane dihydrochlorideTetramethylenediamine dihydrochloride1,4-Butanediamine dihydrochloride1,4-BUTANEDIAMINE, DIHYDROCHLORIDEX45SUR7RHY1,4-Butanediamine, hydrochloride1,4-Diaminobutane, dihydrochlorideNSC 5861

16 more reported names

EINECS 206-375-91,4-Butanediamine, hydrochloride (1:2)AI3-18304Tetramethylenediammonium dichlorideNSC-5861PUTRESCINE DIHYDROCHLORIDE [MI]RefChem:8703801,4Butanediamine, hydrochloride1,4Diaminobutane dihydrochloride1,4Butanediamine, dihydrochloride1,4Diaminobutane, dihydrochloride1,4-Diaminobutane 2HClbutane-1,4-diamine dihydrochloride1,4-Diaminobutane (dihydrochloride)HY-Y1781AC-4426

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:201718
ChEMBL:CHEMBL1528028
EPA DTXSID:DTXSID5059824
PubMed:4650

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Official European Commission record

CosIng substance ID: 101364
Published in the Official Journal: Yes
Recorded by the Commission: 2024-07-01

Open this entry in the official CosIng database

Fields as published by the European Commission. The link opens the entry itself, not a search for it.

Inventory details for PUTRESCINE HCL

INCI name

PUTRESCINE HCL

Description

Putrescine HCl is the organic compound that conforms to the formula

Record provenance

Inventory reference: cosing-live-101364
Imported identity: PUTRESCINE HCL
Source update: 2024-07-01

European Commission CosIng source notes

Annex records for PUTRESCINE HCL

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Key data

CAS

333-93-7

206-375-9

Restriction

—

Function

NOT REPORTED: No function currently reported.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#23719 · PUTRESCINE HCl

Ingredients with overlapping formulation functions

POLYURETHANE-67NOT REPORTED

POLYURETHANE-68NOT REPORTED

PPG-66 DIAMINENOT REPORTED

PROPYLENEDIAMINENOT REPORTED

PYRETHRINSNOT REPORTED

PYRUS MALUS PEEL WAXNOT REPORTED

R-(ASPARTYL OLIGOPEPTIDE-162 ASPARTYL RH-POLYPEPTIDE-115)NOT REPORTED

R-(ASPARTYL OLIGOPEPTIDE-162 ASPARTYL RH-POLYPEPTIDE-48)NOT REPORTED

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How PUTRESCINE HCL appears in the CosIng inventory

The CosIng inventory lists PUTRESCINE HCL as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

PUTRESCINE HCL is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

PUTRESCINE HCL is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, PUTRESCINE HCL carries the following function designation(s):

NOT REPORTED

CAS 333-93-7 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for PUTRESCINE HCL

This page reproduces the CosIng inventory entry for PUTRESCINE HCL from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research PUTRESCINE HCL and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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