What other records share CAS 625-08-1?

CAS 625-08-1 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains 3-METHYL-3-HYDROXYBUTYRIC ACID?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef cosing-live-1011042024-07-04

3-METHYL-3-HYDROXYBUTYRIC ACID

3-Methyl-3-Hydroxybutyric Acid is the organic compound that conforms to the formula

3-METHYL-3-HYDROXYBUTYRIC ACID is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

INCI Checker Compare all markets Search similar

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Markets and their official sources Search every market for this name

Chemical identity and properties

PubChem 2D chemical structure for CAS 625-08-1

CAS 625-08-1PubChem CID 69362

3-Hydroxyisovaleric acid

3-hydroxyisovaleric acid is a 3-hydroxy monocarboxylic acid that is isovaleric acid substituted at position 3 by a hydroxy group. Used as indicator of biotin deficiency. It has a role as a human metabolite. It is functionally related to an isovaleric acid and a butyric acid. It is a conjugate acid of a 3-hydroxyisovalerate. — ChEBI

IUPAC name: 3-hydroxy-3-methylbutanoic acid

Molecular formula: C5H10O3
Molecular weight: 118.13 g/mol
Exact mass: 118.062994177 Da
XLogP3: -0.3
Topological polar surface area: 57.5 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 3
Covalent units: 1
Defined stereocentres: 0

Also known as

beta-Hydroxyisovaleric acid3-Hydroxy-3-methylbutyric acid3-OH-isovaleric acid3-hydroxy-3-methyl-butanoic acid3-hydroxy-isovaleric acidHmb-d6beta-Hydroxy-methylbutyratebeta-hydroxy-beta-methylbutyric acid

16 more reported names

3F752311CDCHEBI:37084RefChem:911412beta hydroxy beta methylbutyratebeta-hydroxy beta-methylbutyrate626-699-8B-hydroxyisovaleric acidButanoic acid, 3-hydroxy-3-methyl-Juven3-hydroxy-3-methyl-Butyric acidButyric acid, 3-hydroxy-3-methyl-.beta.-Hydroxyisovaleric acidbeta-Hydroxyisovaleric Acid-d83-hydroxy-3-methyl butyric acidBeta-(Hydroxyisovaleric Acid)B-hydroxy-b-methylbutyric acid

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:37084
ChEMBL:CHEMBL4303793
EPA DTXSID:DTXSID20211535
PubMed:22713677
PubMed:22705301
PubMed:22624806
PubMed:22619618
PubMed:22512917
PubMed:22477519
PubMed:22457589
PubMed:22348079
PubMed:22346620
PubMed:22277694
PubMed:22242972
PubMed:22234536

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Official European Commission record

CosIng substance ID: 101104
Published in the Official Journal: Yes
Recorded by the Commission: 2024-07-04

Open this entry in the official CosIng database

Fields as published by the European Commission. The link opens the entry itself, not a search for it.

Inventory details for 3-METHYL-3-HYDROXYBUTYRIC ACID

INCI name

3-METHYL-3-HYDROXYBUTYRIC ACID

Description

3-Methyl-3-Hydroxybutyric Acid is the organic compound that conforms to the formula

Record provenance

Inventory reference: cosing-live-101104
Imported identity: 3-METHYL-3-HYDROXYBUTYRIC ACID
Source update: 2024-07-04

European Commission CosIng source notes

Annex records for 3-METHYL-3-HYDROXYBUTYRIC ACID

Browse

Browse EU annexes

Explore Annex II–VI to see which substances are prohibited, restricted or permitted under specific conditions.

Search annex entries

Search the annex database for entries matching 3-METHYL-3-HYDROXYBUTYRIC ACID or related substances.

Key data

CAS

625-08-1

—

Restriction

—

Function

ANTIOXIDANT: Inhibiting reactions promoted by oxygen, thus avoiding oxidation and rancidity.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#292 · 3-METHYL-3-HYDROXYBUTYRIC ACID

Ingredients with overlapping formulation functions

3-ETHYLHEXYLGLYCERYL ASCORBATEANTIOXIDANT, HUMECTANT

3-GLYCERYL ASCORBATEANTIOXIDANT, HUMECTANT

3-LAURYL/TRIDECYLGLYCERYL ASCORBATEANTIOXIDANT, HUMECTANT, SKIN CONDITIONING

3-LAURYLGLYCERYL ASCORBATEANTIOXIDANT, HUMECTANT, SKIN CONDITIONING

4'-METHOXYCHALCONEANTIOXIDANT, BLEACHING, SKIN CONDITIONING

4-BUTYLRESORCINOLANTIOXIDANT

4-FURANYLETHYL RESORCINOLANTIOXIDANT, SKIN CONDITIONING

4-ISOBUTYLRESORCINOLANTIOXIDANT

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How 3-METHYL-3-HYDROXYBUTYRIC ACID appears in the CosIng inventory

The CosIng inventory lists 3-METHYL-3-HYDROXYBUTYRIC ACID as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

3-METHYL-3-HYDROXYBUTYRIC ACID is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

3-METHYL-3-HYDROXYBUTYRIC ACID is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, 3-METHYL-3-HYDROXYBUTYRIC ACID carries the following function designation(s):

ANTIOXIDANT

CAS 625-08-1 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

View CAS records

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Open INCI Checker

Source note for 3-METHYL-3-HYDROXYBUTYRIC ACID

This page reproduces the CosIng inventory entry for 3-METHYL-3-HYDROXYBUTYRIC ACID from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research 3-METHYL-3-HYDROXYBUTYRIC ACID and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

View sources View updates

Tools & next steps

Check your formula

Scan a full INCI list to detect 3-METHYL-3-HYDROXYBUTYRIC ACID and any linked EU annex restrictions or allergen flags.

INCI Checker

Search similar ingredients

Find other inventory ingredients and annex entries related to 3-METHYL-3-HYDROXYBUTYRIC ACID, its identifiers or nearby name variants.