Official EU label nameGlossary entry 292

3-METHYL-3-HYDROXYBUTYRIC ACID

This record confirms an official common ingredient name for EU cosmetic product labelling. It does not by itself confirm that the substance is permitted, unrestricted or safe.

Global evidence snapshot

The resolved identity has matching regulatory evidence in 0 of 13 indexed market datasets: 0 country records and 0 EU Annex records. Every result and evidence gap is listed below.

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Resolved identifiers

Resolved substance identity

CAS:625-08-1

Ingredient index records:

3-METHYL-3-HYDROXYBUTYRIC ACID

Cosmetic functions: ANTIOXIDANT

3-Methyl-3-Hydroxybutyric Acid is the organic compound that conforms to the formula

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1 matched or reported name

3-METHYL-3-HYDROXYBUTYRIC ACID

Regulatory evidence across markets

None of the 13 markets tracked here holds an imported rule under the name 3-METHYL-3-HYDROXYBUTYRIC ACID.

That is a statement about this inventory, not about the law: no imported rule is not evidence that a substance is permitted. A rule may exist under a different name, under a CAS or EC number this glossary entry does not carry, or in a dataset not yet imported.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 625-08-1

CAS 625-08-1PubChem CID 69362

3-Hydroxyisovaleric acid

3-hydroxyisovaleric acid is a 3-hydroxy monocarboxylic acid that is isovaleric acid substituted at position 3 by a hydroxy group. Used as indicator of biotin deficiency. It has a role as a human metabolite. It is functionally related to an isovaleric acid and a butyric acid. It is a conjugate acid of a 3-hydroxyisovalerate. — ChEBI

IUPAC name: 3-hydroxy-3-methylbutanoic acid

Molecular formula: C5H10O3
Molecular weight: 118.13 g/mol
Exact mass: 118.062994177 Da
XLogP3: -0.3
Topological polar surface area: 57.5 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 3
Covalent units: 1
Defined stereocentres: 0

Also known as

beta-Hydroxyisovaleric acid3-Hydroxy-3-methylbutyric acid3-OH-isovaleric acid3-hydroxy-3-methyl-butanoic acid3-hydroxy-isovaleric acidHmb-d6beta-Hydroxy-methylbutyratebeta-hydroxy-beta-methylbutyric acid

16 more reported names

3F752311CDCHEBI:37084RefChem:911412beta hydroxy beta methylbutyratebeta-hydroxy beta-methylbutyrate626-699-8B-hydroxyisovaleric acidButanoic acid, 3-hydroxy-3-methyl-Juven3-hydroxy-3-methyl-Butyric acidButyric acid, 3-hydroxy-3-methyl-.beta.-Hydroxyisovaleric acidbeta-Hydroxyisovaleric Acid-d83-hydroxy-3-methyl butyric acidBeta-(Hydroxyisovaleric Acid)B-hydroxy-b-methylbutyric acid

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External database identifiers

ChEBI:CHEBI:37084
ChEMBL:CHEMBL4303793
EPA DTXSID:DTXSID20211535
PubMed:22713677
PubMed:22705301
PubMed:22624806
PubMed:22619618
PubMed:22512917
PubMed:22477519
PubMed:22457589
PubMed:22348079
PubMed:22346620
PubMed:22277694
PubMed:22242972
PubMed:22234536

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Additional authoritative substance research

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Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal US EPA CompTox CTX APIs

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Official source and scope

Imported from Commission Implementing Decision (EU) 2025/1175 (dataset version EU 2025/1175). The glossary supplies common ingredient names for the ingredient list required by Article 19(1)(g); it is not an approval or safety list.

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