How do I check if my formula contains SR-(METHIONYL HEXAPEPTIDE-40 SACCHAROMYCES POLYPEPTIDE-2 SH-POLYPEPTIDE-134)?

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InventoryRef cosing-live-1001832023-05-23

SR-(METHIONYL HEXAPEPTIDE-40 SACCHAROMYCES POLYPEPTIDE-2 SH-POLYPEPTIDE-134)

SR-(METHIONYL HEXAPEPTIDE-40 SACCHAROMYCES POLYPEPTIDE-2 SH-POLYPEPTIDE-134) is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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What the official INCI name states

The official label identifies a peptide- or protein-related cosmetic material.

Identity type from wording: peptide_or_protein

This structure is derived only from the official label wording. It does not establish composition, concentration, chemical equivalence, safety or regulatory permission.

Official European Commission record

CosIng substance ID: 100183
Entry status: Active
Published in the Official Journal: Yes
Recorded by the Commission: 2023-05-23

Open this entry in the official CosIng database

Fields as published by the European Commission. The link opens the entry itself, not a search for it.

Inventory details for SR-(METHIONYL HEXAPEPTIDE-40 SACCHAROMYCES POLYPEPTIDE-2 SH-POLYPEPTIDE-134)

INCI name

SR-(METHIONYL HEXAPEPTIDE-40 SACCHAROMYCES POLYPEPTIDE-2 SH-POLYPEPTIDE-134)

Description

sr-(Methionyl Hexapeptide-40 Saccharomyces Polypeptide-2 sh-Polypeptide-134) is a single chain recombinant peptide, produced by fermentation in E. coli. The starting gene is synthesized by the fusion of the genes from Hexapeptide-40, r-Saccharomyces Polypeptide-2, and sh-Polypeptide-134 with the initiation codon for methionine. The fusion peptide may contain disulfide bonds and/or glycosylation, and consists of the proper sequence of the 20 standard amino acids

Record provenance

Inventory reference: cosing-live-100183
Imported identity: SR-(METHIONYL HEXAPEPTIDE-40 SACCHAROMYCES POLYPEPTIDE-2 SH-POLYPEPTIDE-134)
Source update: 2023-05-23

European Commission CosIng source notes

Annex records for SR-(METHIONYL HEXAPEPTIDE-40 SACCHAROMYCES POLYPEPTIDE-2 SH-POLYPEPTIDE-134)

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Key data

CAS

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The CosIng inventory records no CAS number for this ingredient. That is the absence of an identifier in the source, not a finding about the substance.

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Restriction

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Function

SKIN CONDITIONING - EMOLLIENT: Acting as lubricants on the skin surface providing the skin with a soft and smooth appearance.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#27493 · sr-(METHIONYL HEXAPEPTIDE-40 SACCHAROMYCES POLYPEPTIDE-2 sh-POLYPEPTIDE-134)

Ingredients with overlapping formulation functions

SPONGESKIN CONDITIONING - EMOLLIENT

SQUALANEHAIR CONDITIONING, REFATTING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

SQUALENEANTISTATIC, HAIR CONDITIONING, REFATTING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

SQUID CARTILAGE EXTRACTSKIN CONDITIONING - EMOLLIENT

SR-(METHIONYL HEXAPEPTIDE-40 SH-POLYPEPTIDE-47 SH-POLYPEPTIDE-158)SKIN CONDITIONING - EMOLLIENT; SKIN PROTECTING; SKIN CONDITIONING - MISCELLANEOUS

SR-(METHIONYL OLIGOPEPTIDE-91 GLUTAMINYL CLOSTRIDIUM BOTULINUM POLYPEPTIDE-1 HE…SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SKIN PROTECTING

SR-(METHIONYL OLIGOPEPTIDE-91 GLUTAMINYL CLOSTRIDIUM BOTULINUM POLYPEPTIDE-1 SH…SKIN CONDITIONING - EMOLLIENT; SKIN PROTECTING

SR-(METHIONYL S-RAINBOW TROUT OLIGOPEPTIDE-1 SH-POLYPEPTIDE-58 HEXAPEPTIDE-40)ANTIOXIDANT; SKIN CONDITIONING - EMOLLIENT; HAIR CONDITIONING; SKIN PROTECTING; SKIN CONDITIONING -…

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How SR-(METHIONYL HEXAPEPTIDE-40 SACCHAROMYCES POLYPEPTIDE-2 SH-POLYPEPTIDE-134) appears in the CosIng inventory

The CosIng inventory lists SR-(METHIONYL HEXAPEPTIDE-40 SACCHAROMYCES POLYPEPTIDE-2 SH-POLYPEPTIDE-134) as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

SR-(METHIONYL HEXAPEPTIDE-40 SACCHAROMYCES POLYPEPTIDE-2 SH-POLYPEPTIDE-134) is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

SR-(METHIONYL HEXAPEPTIDE-40 SACCHAROMYCES POLYPEPTIDE-2 SH-POLYPEPTIDE-134) is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, SR-(METHIONYL HEXAPEPTIDE-40 SACCHAROMYCES POLYPEPTIDE-2 SH-POLYPEPTIDE-134) carries the following function designation(s):

SKIN CONDITIONING - EMOLLIENT

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Source note for SR-(METHIONYL HEXAPEPTIDE-40 SACCHAROMYCES POLYPEPTIDE-2 SH-POLYPEPTIDE-134)

This page reproduces the CosIng inventory entry for SR-(METHIONYL HEXAPEPTIDE-40 SACCHAROMYCES POLYPEPTIDE-2 SH-POLYPEPTIDE-134) from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research SR-(METHIONYL HEXAPEPTIDE-40 SACCHAROMYCES POLYPEPTIDE-2 SH-POLYPEPTIDE-134) and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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