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InventoryRef 3822615/10/2010

SQUALANE

2,6,10,15,19,23-Hexamethyltetracosane

SQUALANE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Chemical identity and properties

PubChem 2D chemical structure for CAS 111-01-3
CAS 111-01-3PubChem CID 8089

Squalane

squalane has been reported in Murraya paniculata with data available. LOTUS - the natural products occurrence database

IUPAC name
2,6,10,15,19,23-hexamethyltetracosane
Molecular formula
C30H62
Molecular weight
422.8 g/mol
Exact mass
422.485151978 Da
XLogP3
14.7
Topological polar surface area
0.0 Ų
Hydrogen-bond donors
0
Hydrogen-bond acceptors
0
Covalent units
1
Defined stereocentres
0

Also known as

PerhydrosqualeneCosbiolRobaneDodecahydrosqualeneHexamethyltetracosaneSpinacaneVitabiosolTetracosane, 2,6,10,15,19,23-hexamethyl-
16 more reported names
Hexamethyl tetracosanePripure 3759NSC-6851footcreamGZE Sweat StickREAROYAFOOTCREAMPURPLE HAIR MASKRefChem:888882Collagen moisturizing creamLGRAMERRETINOLEYECREAMYOUNGCOME SNOW BLEACHLGRAMER PURPLE HAIR MASKLGRAMERCollagenmoisturizingcreamYOUNGCOMEMOISTURIZINGCREAMHyaluronic acid facial care creamLgramer Hand and Foot Care Cream
External database identifiers

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match8089

Attributed physical-property, hazard, environmental and use annotations.

  • GHS Hazard Statements: Not Classified; Reported as not meeting GHS hazard criteria by 350 of 391 companies Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 391 reports by companies from 6 notifications to the ECHA C&L Inventory.; Reported as not meeting GHS hazard criteria per 350 of 391 reports by companies.; There are 4 notifications provided by 41 of 391 reports by companies with hazard statement code(s).; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • Cosmetic Ingredient Review Finding(s): Safe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org Source: Cosmetic Ingredient Review (CIR)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for SQUALANE

INCI name

SQUALANE

INN name

squalane

Description

2,6,10,15,19,23-Hexamethyltetracosane

Record provenance

Inventory reference
38226
Imported identity
SQUALANE
Source update
15/10/2010
European Commission CosIng source notes

Key data

Restriction
Function
HAIR CONDITIONING
Enhancing the appearance and feel of hair. Leaving the hair easy to comb, supple, soft and shiny and/or imparting volume, lightness, gloss, texture, etc.
REFATTING
Replenishing the lipids of the hair or of the top layers of the skin.
SKIN CONDITIONING
Maintaining the skin in good condition.
SKIN CONDITIONING - EMOLLIENT
Acting as lubricants on the skin surface providing the skin with a soft and smooth appearance.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How SQUALANE appears in the CosIng inventory

The CosIng inventory lists SQUALANE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

SQUALANE is also tagged with 4 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

SQUALANE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, SQUALANE carries the following function designation(s):

CAS 111-01-3 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for SQUALANE

This page reproduces the CosIng inventory entry for SQUALANE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research SQUALANE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

Tools & next steps

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