Is HUMAN UMBILICAL MESENCHYMAL STEM CELL CONDITIONED MEDIA EXTRACT safe to use in EU cosmetics?

HUMAN UMBILICAL MESENCHYMAL STEM CELL CONDITIONED MEDIA EXTRACT appears in the EU CosIng inventory and has linked annex records. Check the annex records for applicable restrictions, concentration limits and conditions of use. Annex II means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

How do I check if my formula contains HUMAN UMBILICAL MESENCHYMAL STEM CELL CONDITIONED MEDIA EXTRACT?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 9755721/10/2019

HUMAN UMBILICAL MESENCHYMAL STEM CELL CONDITIONED MEDIA EXTRACT

Human Umbilical Mesenchymal Stem Cell Conditioned Media Extract is the extract of the growth media removed from cultures of human umbilical mesenchymal stem cells after several days of growth. The starting media is Dulb…

HUMAN UMBILICAL MESENCHYMAL STEM CELL CONDITIONED MEDIA EXTRACT is linked to 1 EU annex record on this page. Inventory note: II/416.

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Regulatory evidence by market

This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.

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Market	Evidence status	Records	Source language
European Union	Evidence linked Prohibited entry found Open this evidence	1	English and EU languages
Great Britain	Source mapped Official source mapped; ingredient rule not imported	0	English
Canada	Source mapped Official source mapped; ingredient rule not imported	0	English and French
New Zealand	Source mapped Official source mapped; ingredient rule not imported	0	English
ASEAN	Source mapped Official source mapped; ingredient rule not imported	0	English and national languages
China	Source mapped Official source mapped; ingredient rule not imported	0	Chinese with selected English material
Japan	Source mapped Official source mapped; ingredient rule not imported	0	Japanese; official English translation available
South Korea	Source mapped Official source mapped; ingredient rule not imported	0	Korean with some English names
United States	Source mapped Official source mapped; ingredient rule not imported	0	English
Australia	Source mapped Official source mapped; ingredient rule not imported	0	English
Brazil	Source mapped Official source mapped; ingredient rule not imported	0	Portuguese with INCI crosswalks
India	Source mapped Official source mapped; ingredient rule not imported	0	English and Hindi
Saudi Arabia	Source mapped Official source mapped; ingredient rule not imported	0	Arabic and English

What the official INCI name states

The official label identifies a biological source material and its stated preparation or plant part.

Identity type from wording: biological_material
Preparation or form: CONDITIONED MEDIA, EXTRACT
Stated biological parts: STEM, CELL

Scientific-name candidates to verify against the supplier specification

Cell conditioned

This structure is derived only from the official label wording. It does not establish composition, concentration, chemical equivalence, safety or regulatory permission.

Inventory details for HUMAN UMBILICAL MESENCHYMAL STEM CELL CONDITIONED MEDIA EXTRACT

INCI name

HUMAN UMBILICAL MESENCHYMAL STEM CELL CONDITIONED MEDIA EXTRACT

Description

Record provenance

Inventory reference: 97557
Imported identity: HUMAN UMBILICAL MESENCHYMAL STEM CELL CONDITIONED MEDIA EXTRACT
Source update: 21/10/2019

European Commission CosIng source notes

Annex records for HUMAN UMBILICAL MESENCHYMAL STEM CELL CONDITIONED MEDIA EXTRACT

Annex II Restriction reference

Entry 416

Cells, tissues or products of human origin

Key data

CAS

—

No CAS number, and none is expected: this is a botanical or biological preparation rather than a single compound, and CAS numbers identify single substances. Identity rests on the source organism and the supplier specification.

—

Restriction

II/416

Function

ANTIOXIDANT: Inhibiting reactions promoted by oxygen, thus avoiding oxidation and rancidity.
HUMECTANT: Retaining and/or preserving the moisture in a product during use.
SKIN PROTECTING: Helping to avoid harmful effects to the skin from external factors.
SOLVENT: Dissolving other components of cosmetics. Solvents are usually liquids (aqueous and nonaqueous).

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#12288 · HUMAN UMBILICAL MESENCHYMAL STEM CELL CONDITIONED MEDIA EXTRACT

Ingredients with overlapping formulation functions

HEXYLENE GLYCOLPERFUMING, SKIN CONDITIONING, SOLVENT, SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING

HEXYLOXYETHANOLSOLVENT

HIPPOPHAE RHAMNOIDES FRUIT WATERSOLVENT

HUMAN BONE MARROW STEM CELL CONDITIONED MEDIA EXTRACTBLEACHING, HUMECTANT, ORAL CARE, SKIN CONDITIONING, SKIN PROTECTING, SOLVENT

HUMAN UMBILICAL WHARTON'S JELLY MESENCHYMAL STEM CELL CONDITIONED MEDIAANTIOXIDANT; HUMECTANT; SKIN PROTECTING; SOLVENT; SKIN CONDITIONING - HUMECTANT

HUMAN UMBILICAL WHARTON'S JELLY MESENCHYMAL STEM CELL EXOSOMESANTIOXIDANT; HUMECTANT; SKIN PROTECTING; SOLVENT; SKIN CONDITIONING - HUMECTANT

HYDROGENATED FARNESENESKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SOLVENT

HYDROGENATED POLYDECENEFRAGRANCE, HAIR CONDITIONING, PERFUMING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SOLVENT

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How HUMAN UMBILICAL MESENCHYMAL STEM CELL CONDITIONED MEDIA EXTRACT appears in the CosIng inventory

The CosIng inventory lists HUMAN UMBILICAL MESENCHYMAL STEM CELL CONDITIONED MEDIA EXTRACT as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

HUMAN UMBILICAL MESENCHYMAL STEM CELL CONDITIONED MEDIA EXTRACT is also tagged with 4 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

HUMAN UMBILICAL MESENCHYMAL STEM CELL CONDITIONED MEDIA EXTRACT appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for HUMAN UMBILICAL MESENCHYMAL STEM CELL CONDITIONED MEDIA EXTRACT reads: "II/416". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, HUMAN UMBILICAL MESENCHYMAL STEM CELL CONDITIONED MEDIA EXTRACT carries the following function designation(s):

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Source note for HUMAN UMBILICAL MESENCHYMAL STEM CELL CONDITIONED MEDIA EXTRACT

This page combines the CosIng inventory entry for HUMAN UMBILICAL MESENCHYMAL STEM CELL CONDITIONED MEDIA EXTRACT with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research HUMAN UMBILICAL MESENCHYMAL STEM CELL CONDITIONED MEDIA EXTRACT and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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