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InventoryRef 9737330/07/2020

AMINOETHYLETHANOLAMINE

Ethanol, 2-[(2-aminoethyl)amino]-,Hydroxyethyl Ethylenediamine

AMINOETHYLETHANOLAMINE is linked to 1 EU annex record on this page. Inventory note: II/1471.

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Regulatory evidence by market

This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.

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MarketEvidence statusRecordsSource language
European UnionEvidence linked
Prohibited entry found
Open this evidence		1English and EU languages
Great BritainEvidence linked
Prohibited
Open this evidence		1English
CanadaSource mapped
Official source mapped; ingredient rule not imported
0English and French
New ZealandEvidence linked
Prohibited
Open this evidence		1English
ASEANEvidence linked
Prohibited
Open this evidence		1English and national languages
ChinaSource mapped
Official source mapped; ingredient rule not imported
0Chinese with selected English material
JapanSource mapped
Official source mapped; ingredient rule not imported
0Japanese; official English translation available
South KoreaSource mapped
Official source mapped; ingredient rule not imported
0Korean with some English names
United StatesSource mapped
Official source mapped; ingredient rule not imported
0English
AustraliaSource mapped
Official source mapped; ingredient rule not imported
0English
BrazilSource mapped
Official source mapped; ingredient rule not imported
0Portuguese with INCI crosswalks
IndiaEvidence linked
Prohibited
Open this evidence		1English and Hindi
Saudi ArabiaEvidence linked
Prohibited
Open this evidence		1Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 111-41-1
CAS 111-41-1PubChem CID 8112

N-(2-Hydroxyethyl)ethylenediamine

Aminoethylethanolamine appears as a clear colorless liquid with an ammonia-like odor. Corrosive to tissue. Combustible, but may be difficult to ignite. Less dense than water. Vapors heavier than air. Toxic oxides of nitrogen produced during combustion. Used to make other chemicals. — CAMEO Chemicals

IUPAC name
2-(2-aminoethylamino)ethanol
Molecular formula
C4H12N2O
Molecular weight
104.15 g/mol
Exact mass
104.094963011 Da
XLogP3
-1.7
Topological polar surface area
58.3 Ų
Hydrogen-bond donors
3
Hydrogen-bond acceptors
3
Covalent units
1
Defined stereocentres
0

Also known as

monoethanol ethylenediamineRefChem:112035Aminoethylethanolamine2-((2-Aminoethyl)amino)ethanolN-(Hydroxyethyl)ethylenediamineN-(2-Aminoethyl)ethanolamineN-(Aminoethyl)ethanolamine(2-Hydroxyethyl)ethylenediamine
16 more reported names
MonoethanolethylenediamineEthanol, 2-[(2-aminoethyl)amino]-(2-Aminoethyl)ethanolamine2-[(2-Aminoethyl)amino]ethanolEthanolethylene diamineN-Hydroxyethyl-1,2-ethanediamineN-Hydroxyethylethylenediamine2-[(2-aminoethyl)amino]ethan-1-olN-(2-Hydroxyethyl)-1,2-ethanediamineNSC 461Ethanol, 2-((2-aminoethyl)amino)-2-((Aminoethyl)amino)ethanol2-[2-Aminoethylamino]ethanolTrimetazidine Impurity PRC78W6NPXT1-(2-(Hydroxyethyl)amino)-2-aminoethane
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Evidence from additional scientific databases

NIH PubChem PUG-View
Exact identifier match8112

Attributed physical-property, hazard, environmental and use annotations.

  • First Aid: EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.; SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.; INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) shou Source: CAMEO Chemicals
  • Signal: Danger Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • GHS Hazard Statements: H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]; H317: May cause an allergic skin reaction [Warning Sensitization, Skin]; H360Df: May damage the unborn child; Suspected of damaging fertility [Danger Reproductive toxicity] Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Precautionary Statement Codes: P203, P260, P261, P264, P272, P280, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P318, P321, P333+P317, P362+P364, P363, P405, and P501 (click each P-code to see the statement) Source: Regulation (EC) No 1272/2008 of the European Parliament and of the Council
  • Signal: Danger Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H290 (13.6%): May be corrosive to metals [Warning Corrosive to Metals]; H314 (99.4%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]; H317 (> 99.9%): May cause an allergic skin reaction [Warning Sensitization, Skin]; H318 (19%): Causes serious eye damage [Danger Serious eye damage/eye irritation]; H335 (17.8%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]; H360 (99.8%): May damage fertility or the unborn child [Danger Reproductive toxicity] Source: European Chemicals Agency (ECHA)
  • Precautionary Statement Codes: P203, P234, P260, P261, P264, P264+P265, P271, P272, P280, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P318, P319, P321, P333+P317, P362+P364, P363, P390, P403+P233, P405, P406, and P501 (click each P-code to see the statement) Source: European Chemicals Agency (ECHA)
  • ECHA C&L Notifications Summary: Aggregated GHS information provided per 3278 reports by companies from 41 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.; Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. Source: European Chemicals Agency (ECHA)
  • GHS Hazard Statements: H402: Harmful to aquatic life [Hazardous to the aquatic environment, acute hazard]; H412: Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] Source: NITE-CMC
  • Precautionary Statement Codes: P273, and P501 (click each P-code to see the statement) Source: NITE-CMC
  • Signal: Danger Source: NITE-CMC
  • GHS Hazard Statements: H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]; H317: May cause an allergic skin reaction [Warning Sensitization, Skin]; H318: Causes serious eye damage [Danger Serious eye damage/eye irritation]; H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory]; H360: May damage fertility or the unborn child [Danger Reproductive toxicity]; H373: May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]; H402: Harmful to aquatic life [Hazardous to the aquatic environment, acute hazard]; H412: Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] Source: NITE-CMC
  • Precautionary Statement Codes: P203, P233, P260, P261, P264, P264+P265, P271, P272, P273, P280, P284, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P318, P319, P321, P333+P317, P342+P316, P362+P364, P363, P403, P405, and P501 (click each P-code to see the statement) Source: NITE-CMC
  • NFPA Health Rating: 2 - Materials that, under emergency conditions, can cause temporary incapacitation or residual injury. Source: Hazardous Substances Data Bank (HSDB)
  • NFPA Fire Rating: 1 - Materials that must be preheated before ignition can occur. Materials require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur. Source: Hazardous Substances Data Bank (HSDB)
  • NFPA Instability Rating: 0 - Materials that in themselves are normally stable, even under fire conditions. Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Bioconcentration: Based upon an estimated log Kow of -1.39(1), the BCF for aminoethyl ethanolamine can be estimated to be 0.05 from a recommended regression-derived equation(2,SRC). This estimated BCF value indicates that bioconcentration in aquatic organisms is not important. Aminoethyl ethanolamine is miscible in water(3) which also indicates that bioconcentration is not important(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: TERRESTRIAL FATE: The results of one biodegradation screening study have indicated that aminoethyl ethanolamine biodegrades readily(1); therefore, biodegradation may be an important transformation process in soil(SRC). Aminoethyl ethanolamine has a pKa of 7.21(2) that indicates it can exist in both the protonated and neutral forms in environmental media; neutral aminoethyl ethanolamine is expected to leach readily. However, the mobility of protonated aminoethyl ethanolamine in soil can not be predicted without additional experimental data(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: AQUATIC FATE: The results of one biodegradation screening study have indicated that aminoethyl ethanolamine biodegrades readily(1); therefore, biodegradation may be an important transformation process in water. Aquatic bioconcentration and volatilization are not expected to be important because of the high solubility of aminoethyl ethanolamine(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Environmental Fate: ATMOSPHERIC FATE: Based upon a vapor pressure of 8.19X10-4 mm Hg at 25 °C(1), aminoethyl ethanolamine is expected to exist primarily in the vapor-phase in the ambient atmosphere(2,SRC). It will degrade rapidly in the atmosphere by the vapor-phase reaction with photochemically produced hydroxyl radicals with an estimated half-life of 3.3 hr(3,SRC). Aminoethyl ethanolamine is miscible with water(4), therefore, physical removal from air by wet deposition (dissolution in clouds, rainfall, etc) is possible(SRC). Source: Hazardous Substances Data Bank (HSDB)
  • Sources/Uses: Used as a chemical intermediate, textile finishing compound, and additive to oils in metal cutting; [HSDB] Occupational asthma reported in solderer and cable jointer; [Malo] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Industrial Processes with risk of exposure: Metal Machining [Category: Heat or Machine]; Soldering [Category: Heat or Machine]; Semiconductor Manufacturing [Category: Industry]; Textiles (Printing, Dyeing, or Finishing) [Category: Industry] Source: Haz-Map, Information on Hazardous Chemicals and Occupational Diseases
  • Uses: CHEM INT FOR CHELATING AGENTS, DETERGENTS & EMULSIFIERS, CORROSION INHIBITORS, MINING CHEMICALS, GASOLINE STABILIZERS, DYEING ASSISTANTS, MODIFYING AGENTS (TEXTILES), 2,4-D HERBICIDE SALTS, OILS USED IN TEXTILE PROCESSING, OILS USED IN METAL CUTTING, AND GAS PROCESSING CHEMICALS Source: Hazardous Substances Data Bank (HSDB)
  • Uses: TEXTILE FINISHING CMPD (ANTIFUMING AGENTS, DYESTUFFS, CATIONIC SURFACTANTS); RESINS, RUBBER PRODUCTS; INSECTICIDES, CERTAIN MEDICINALS Source: Hazardous Substances Data Bank (HSDB)

Mapped by: Existing checksum-valid CAS to unique PubChem CID match. Retrieved: 2026-08-31. Open source record

Scientific classifications and hazard annotations provide context and do not replace the market-specific regulatory decision shown above.

Additional source coverage and match status
SourceResultChecked
NIH PubChem PUG-ViewExact match2026-08-31

A recorded no-match is useful evidence that the source was checked; it is not a claim that the substance does not exist elsewhere.

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for AMINOETHYLETHANOLAMINE

INCI name

AMINOETHYLETHANOLAMINE

Description

Ethanol, 2-[(2-aminoethyl)amino]-,Hydroxyethyl Ethylenediamine

Record provenance

Inventory reference
97373
Imported identity
AMINOETHYLETHANOLAMINE
Source update
30/07/2020
European Commission CosIng source notes

Key data

CAS
111-41-1
EC
203-867-5
Restriction
II/1471
Function
NOT REPORTED
No function currently reported.

Ingredients with overlapping formulation functions

ALLYL T-BUTYLIMIDAZO BENZIMIDAZOLENOT REPORTED
ALPINIA ZERUMBET FLOWER EXTRACTNOT REPORTED
AMELANCHIER ARBOREA EXTRACTNOT REPORTED
AMINOETHOXYMETHYL PYRROLOPYRIMIDONENOT REPORTED
AMINOHEXYL GUANINENOT REPORTED
AMINOPENTYL AMINOADENINENOT REPORTED
AMINOPENTYL GUANINENOT REPORTED
AMINOPROPYLTRIISOPROPOXYSILANENOT REPORTED

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicalsPubChem PUG RESTEU Safety Gate cosmetic product alertsECHA CHEMUS EPA CompToxCosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortal

How AMINOETHYLETHANOLAMINE appears in the CosIng inventory

The CosIng inventory lists AMINOETHYLETHANOLAMINE as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

AMINOETHYLETHANOLAMINE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

AMINOETHYLETHANOLAMINE appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for AMINOETHYLETHANOLAMINE reads: "II/1471". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, AMINOETHYLETHANOLAMINE carries the following function designation(s):

CAS 111-41-1 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.
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Source note for AMINOETHYLETHANOLAMINE

This page combines the CosIng inventory entry for AMINOETHYLETHANOLAMINE with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research AMINOETHYLETHANOLAMINE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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