What does the restriction note for HUMAN BLOOD LYMPHOCYTE CONDITIONED MEDIA mean?

The restriction field for HUMAN BLOOD LYMPHOCYTE CONDITIONED MEDIA reads: II/416. This is the restriction note from the CosIng inventory. For authoritative conditions and limits, always refer to the linked annex entries.

How do I check if my formula contains HUMAN BLOOD LYMPHOCYTE CONDITIONED MEDIA?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 9653805/04/2019

HUMAN BLOOD LYMPHOCYTE CONDITIONED MEDIA

Human Blood Lymphocyte Conditioned Media is the growth media removed from cultures of lymphocytes isolated from human blood after several days of growth.

HUMAN BLOOD LYMPHOCYTE CONDITIONED MEDIA is linked to 1 EU annex record on this page. Inventory note: II/416.

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Regulatory evidence by market

This matrix separates verified ingredient rules from sources that are mapped but not yet imported. No imported rule does not mean the ingredient is permitted.

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Market	Evidence status	Records	Source language
European Union	Evidence linked Prohibited entry found Open this evidence	1	English and EU languages
Great Britain	Source mapped Official source mapped; ingredient rule not imported	0	English
Canada	Source mapped Official source mapped; ingredient rule not imported	0	English and French
New Zealand	Source mapped Official source mapped; ingredient rule not imported	0	English
ASEAN	Source mapped Official source mapped; ingredient rule not imported	0	English and national languages
China	Source mapped Official source mapped; ingredient rule not imported	0	Chinese with selected English material
Japan	Source mapped Official source mapped; ingredient rule not imported	0	Japanese; official English translation available
South Korea	Source mapped Official source mapped; ingredient rule not imported	0	Korean with some English names
United States	Source mapped Official source mapped; ingredient rule not imported	0	English
Australia	Source mapped Official source mapped; ingredient rule not imported	0	English
Brazil	Source mapped Official source mapped; ingredient rule not imported	0	Portuguese with INCI crosswalks
India	Source mapped Official source mapped; ingredient rule not imported	0	English and Hindi
Saudi Arabia	Source mapped Official source mapped; ingredient rule not imported	0	Arabic and English

Exact external identity check

not_found

No complete-name PubChem match was verified. The material may be a mixture, trade-style INCI identity or be indexed under another identifier; this result must not be read as proof that no related chemistry exists.

Exact CosIng INCI name equals a PubChem synonym · Checked 2026-08-31

What the official INCI name states

The official glossary supplies the label identity; no composition is inferred from the name alone.

Identity type from wording: single_or_unspecified_identity
Preparation or form: CONDITIONED MEDIA

This structure is derived only from the official label wording. It does not establish composition, concentration, chemical equivalence, safety or regulatory permission.

Inventory details for HUMAN BLOOD LYMPHOCYTE CONDITIONED MEDIA

INCI name

HUMAN BLOOD LYMPHOCYTE CONDITIONED MEDIA

Description

Human Blood Lymphocyte Conditioned Media is the growth media removed from cultures of lymphocytes isolated from human blood after several days of growth.

Record provenance

Inventory reference: 96538
Imported identity: HUMAN BLOOD LYMPHOCYTE CONDITIONED MEDIA
Source update: 05/04/2019

European Commission CosIng source notes

Annex records for HUMAN BLOOD LYMPHOCYTE CONDITIONED MEDIA

Annex II Restriction reference

Entry 416

Cells, tissues or products of human origin

Key data

CAS

—

The CosIng inventory records no CAS number for this ingredient. That is the absence of an identifier in the source, not a finding about the substance.

—

Restriction

II/416

Function

BLEACHING: Bleaching or lightening the shade of hair and/or skin.
SKIN PROTECTING: Helping to avoid harmful effects to the skin from external factors.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#12201 · HUMAN BLOOD LYMPHOCYTE CONDITIONED MEDIA

Ingredients with overlapping formulation functions

HONOKIOLANTIOXIDANT, BLEACHING, SKIN CONDITIONING

HUMAN ADIPOSE DERIVED STEM CELL CONDITIONED MEDIABLEACHING, SKIN CONDITIONING

HUMAN ADIPOSE-DERIVED STEM CELL CONDITIONED MEDIABLEACHING; SKIN CONDITIONING - MISCELLANEOUS

HUMAN BLOOD CELL-DERIVED INDUCED PLURIPOTENT CELL EXTRACELLULAR VESICLESBLEACHING; SKIN PROTECTING; SKIN CONDITIONING - HUMECTANT; SKIN CONDITIONING - MISCELLANEOUS

HUMAN BONE MARROW STEM CELL CONDITIONED MEDIA EXTRACTBLEACHING, HUMECTANT, ORAL CARE, SKIN CONDITIONING, SKIN PROTECTING, SOLVENT

HUMAN UMBILICAL CORD MESENCHYMAL STEM CELL CONDITIONED MEDIA EXTRACTANTIOXIDANT; ANTI-SEBUM; BLEACHING; BULKING; SKIN PROTECTING

HYDROLYZED ASPERGILLUS/GINSENG EXTRACT FERMENTANTIOXIDANT, BLEACHING

HYDROLYZED BETA MARITIMA EXTRACTBLEACHING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How HUMAN BLOOD LYMPHOCYTE CONDITIONED MEDIA appears in the CosIng inventory

The CosIng inventory lists HUMAN BLOOD LYMPHOCYTE CONDITIONED MEDIA as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

HUMAN BLOOD LYMPHOCYTE CONDITIONED MEDIA is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

HUMAN BLOOD LYMPHOCYTE CONDITIONED MEDIA appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for HUMAN BLOOD LYMPHOCYTE CONDITIONED MEDIA reads: "II/416". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, HUMAN BLOOD LYMPHOCYTE CONDITIONED MEDIA carries the following function designation(s):

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Source note for HUMAN BLOOD LYMPHOCYTE CONDITIONED MEDIA

This page combines the CosIng inventory entry for HUMAN BLOOD LYMPHOCYTE CONDITIONED MEDIA with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research HUMAN BLOOD LYMPHOCYTE CONDITIONED MEDIA and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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