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InventoryRef 9574418/04/2018

TRIHYDROXYDIHYDROCHALCONE

Davidigenin,Dihydrotrihydroxychalcone,1-Propanone, 1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-

TRIHYDROXYDIHYDROCHALCONE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Chemical identity and properties

PubChem 2D chemical structure for CAS 23130-26-9
CAS 23130-26-9PubChem CID 442342

Davidigenin

Davidigenin is a member of the class of dihydrochalcones that is dihydrochalcone substituted by hydroxy groups at positions 4, 2', and 4' respectively. It has a role as an antioxidant, a metabolite, an anti-allergic agent and an anti-asthmatic agent. It is a polyphenol and a member of dihydrochalcones. It is functionally related to a dihydrochalcone. ChEBI

IUPAC name
1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)propan-1-one
Molecular formula
C15H14O4
Molecular weight
258.27 g/mol
Exact mass
258.08920892 Da
XLogP3
3.0
Topological polar surface area
77.8 Ų
Hydrogen-bond donors
3
Hydrogen-bond acceptors
4
Covalent units
1
Defined stereocentres
0

Also known as

2',4,4'-TrihydroxydihydrochalconeIsoliquiritigenin metabolite M5OML9B432G44,2',4'-Trihydroxydihydrochalcone1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-1-propanone1-Propanone, 1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-CHEBI:27655RefChem:131023
7 more reported names
2',4'-Dihydroxy-3-(p-hydroxyphenyl)-propiophenoneCompound NP-007307UNII-OML9B432G4UDGKKUWYNITJRX-UHFFFAOYSA-NHY-W983015DB-0813461- (2,4-Dihydroxyphenyl) -3- (4-hydroxyphenyl) -1-propanone
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for TRIHYDROXYDIHYDROCHALCONE

INCI name

TRIHYDROXYDIHYDROCHALCONE

Description

Davidigenin,Dihydrotrihydroxychalcone,1-Propanone, 1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-

Record provenance

Inventory reference
95744
Imported identity
TRIHYDROXYDIHYDROCHALCONE
Source update
18/04/2018
European Commission CosIng source notes

Key data

EC
Restriction
Function
SKIN CONDITIONING
Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How TRIHYDROXYDIHYDROCHALCONE appears in the CosIng inventory

The CosIng inventory lists TRIHYDROXYDIHYDROCHALCONE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

TRIHYDROXYDIHYDROCHALCONE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

TRIHYDROXYDIHYDROCHALCONE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, TRIHYDROXYDIHYDROCHALCONE carries the following function designation(s):

CAS 23130-26-9 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for TRIHYDROXYDIHYDROCHALCONE

This page reproduces the CosIng inventory entry for TRIHYDROXYDIHYDROCHALCONE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research TRIHYDROXYDIHYDROCHALCONE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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