Is ZEATIN safe to use in EU cosmetics?

ZEATIN is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What other records share CAS 1637-39-4?

CAS 1637-39-4 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains ZEATIN?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 8390915/10/2010

ZEATIN

2-Buten-1-ol, 2-methyl-4-(1H-purin-6-ylamino)-, (2E)-

ZEATIN is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 1637-39-4

CAS 1637-39-4PubChem CID 449093

Zeatin

Zeatin is a 6-isopentenylaminopurine. It has a role as a cytokinin. — ChEBI

IUPAC name: (E)-2-methyl-4-(7H-purin-6-ylamino)but-2-en-1-ol

Molecular formula: C10H13N5O
Molecular weight: 219.24 g/mol
Exact mass: 219.11201006 Da
XLogP3: 0.7
Topological polar surface area: 86.7 Å²
Hydrogen-bond donors: 3
Hydrogen-bond acceptors: 5
Covalent units: 1
Defined stereocentres: 0

Also known as

trans-Zeatin(E)-ZeatinZeatine(E)-2-methyl-4-(1H-purin-6-ylamino)-2-buten-1-olN6-(4-Hydroxyisopentenyl)adenine2-Buten-1-ol, 2-methyl-4-(1H-purin-6-ylamino)-, (2E)-7I6OOJ9GR62-Buten-1-ol, 2-methyl-4-(1H-purin-6-ylamino)-, (E)-

16 more reported names

(E)-2-Methyl-4-(1H-purin-6-ylamino)but-2-en-1-ol(E)-2-methyl-4-(purin-6-ylamino)-2-buten-1-ol(2E)-2-methyl-4-(1H-purin-6-ylamino)-2-buten-1-olCHEBI:15333CHEBI:165222-BUTEN-1-OL, 2-METHYL-4-(PURIN-6-YLAMINO)-, (E)-(2E)-2-methyl-4-((7H-purin-6-yl)amino)but-2-en-1-ol(2E)-2-methyl-4-[(7H-purin-6-yl)amino]but-2-en-1-olRefChem:898920605-343-5(E/Z)-Zeatin(2E)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol2-buten-1-ol, 2-methyl-4-(9H-purin-6-ylamino)-, (2E)-trans-6-(4-Hydroxy-3-methylbut-2-enyl)amino purine(E)-4-((9H-purin-6-yl)amino)-2-methylbut-2-en-1-ol2-Buten-1-ol, 2-methyl-4-(9H-purin-6-ylamino)-

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:15333
ChEBI:CHEBI:16522
ChEMBL:CHEMBL525239
EPA DTXSID:DTXSID9040631
PubMed:19459726
PubMed:11479373
PubMed:4719

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for ZEATIN

INCI name

ZEATIN

Description

2-Buten-1-ol, 2-methyl-4-(1H-purin-6-ylamino)-, (2E)-

Record provenance

Inventory reference: 83909
Imported identity: ZEATIN
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for ZEATIN

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Key data

CAS

1637-39-4

—

Restriction

—

Function

SKIN CONDITIONING: Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#30273 · ZEATIN

Ingredients with overlapping formulation functions

ZEA MAYS OIL UNSAPONIFIABLESHAIR CONDITIONING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

ZEA MAYS SILK EXTRACTSKIN CONDITIONING

ZEA MAYS STALK EXTRACTSKIN CONDITIONING

ZEA MAYS STIGMA EXTRACTHUMECTANT, SKIN CONDITIONING

ZEDERONESKIN CONDITIONING

ZEINFILM FORMING, HAIR CONDITIONING, SKIN CONDITIONING

ZERUMBONESKIN CONDITIONING

ZINC ACETYLMETHIONATESKIN CONDITIONING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How ZEATIN appears in the CosIng inventory

The CosIng inventory lists ZEATIN as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

ZEATIN is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

ZEATIN is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, ZEATIN carries the following function designation(s):

SKIN CONDITIONING

CAS 1637-39-4 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for ZEATIN

This page reproduces the CosIng inventory entry for ZEATIN from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research ZEATIN and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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