Is PIRACETAM safe to use in EU cosmetics?

PIRACETAM is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What other records share CAS 7491-74-9?

CAS 7491-74-9 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains PIRACETAM?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 8379715/10/2010

PIRACETAM

1-Pyrrolidineacetamide, 2-Oxo-

PIRACETAM is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 7491-74-9

CAS 7491-74-9PubChem CID 4843

Piracetam

Piracetam is an organonitrogen compound and an organooxygen compound. It is functionally related to an alpha-amino acid. — ChEBI

IUPAC name: 2-(2-oxopyrrolidin-1-yl)acetamide

Molecular formula: C6H10N2O2
Molecular weight: 142.16 g/mol
Exact mass: 142.074227566 Da
XLogP3: -1.3
Topological polar surface area: 63.4 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 2
Covalent units: 1
Defined stereocentres: 0

Also known as

2-Oxo-1-pyrrolidineacetamideNootropilNootropylNormabrainPyracetamPyramemPirazetamMyocalm

16 more reported names

2-PyrrolidinoneacetamidePiracetamumNootropCl-8711-Acetamido-2-pyrrolidinone2-Ketopyrrolidine-1-ylacetamideNSC-758191ZH516LNZ10Piracetam RPhPiracetam-RPhMemo Puren2-Pyrrolidone-N-AcetamideUCB6215Nootrop 400Nootrop 800Nootrop 1200

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:32010
ChEMBL:CHEMBL36715
EPA DTXSID:DTXSID5044491
PubMed:40226982
PubMed:28441890
PubMed:27717698
PubMed:26434561
PubMed:23066555
PubMed:23045722
PubMed:23033650
PubMed:23025044
PubMed:22988718
PubMed:22988323
PubMed:22972056
PubMed:22972044

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for PIRACETAM

INCI name

PIRACETAM

Description

1-Pyrrolidineacetamide, 2-Oxo-

Record provenance

Inventory reference: 83797
Imported identity: PIRACETAM
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for PIRACETAM

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Key data

CAS

7491-74-9

231-312-7

Restriction

—

Function

SKIN CONDITIONING: Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#21247 · PIRACETAM

Ingredients with overlapping formulation functions

PIPERIDINEPROPIONIC ACIDSKIN CONDITIONING

PIPERLONGUMINEANTIOXIDANT, BLEACHING, SKIN CONDITIONING

PIPERLONGUMININEANTIMICROBIAL, ANTIOXIDANT, SKIN CONDITIONING

PIPERONYLIC ACIDSKIN CONDITIONING, SKIN PROTECTING

PISCES EXTRACTMOISTURISING, SKIN CONDITIONING

PISCUM CARTILAGE EXTRACTSKIN CONDITIONING

PISCUM IECUR OILSKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

PISCUM OVUM EXTRACTSKIN CONDITIONING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How PIRACETAM appears in the CosIng inventory

The CosIng inventory lists PIRACETAM as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

PIRACETAM is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

PIRACETAM is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, PIRACETAM carries the following function designation(s):

SKIN CONDITIONING

CAS 7491-74-9 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for PIRACETAM

This page reproduces the CosIng inventory entry for PIRACETAM from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research PIRACETAM and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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