Is LAUROCAPRAM safe to use in EU cosmetics?

LAUROCAPRAM is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Always verify against the current official CosIng database before formulating.

What other records share CAS 59227-89-3?

CAS 59227-89-3 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains LAUROCAPRAM?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 8377315/10/2010

LAUROCAPRAM

2H-Azepin-2-one, 1-dodecylhexahydro-

LAUROCAPRAM is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

INCI Checker Compare all markets Search similar

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Markets and their official sources Search every market for this name

Chemical identity and properties

PubChem 2D chemical structure for CAS 59227-89-3

CAS 59227-89-3PubChem CID 42981

Laurocapram

Laurocapram is a percutaneous enhancer. Upon application to the skin, laurocapram interacts with lipids in the stratum corneum and may enhance the ability of the skin to absorb a hydrophilic chemical. — NCI Thesaurus (NCIt)

IUPAC name: 1-dodecylazepan-2-one

Molecular formula: C18H35NO
Molecular weight: 281.5 g/mol
Exact mass: 281.271864740 Da
XLogP3: 5.9
Topological polar surface area: 20.3 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 1
Covalent units: 1
Defined stereocentres: 0

Also known as

Azone2H-Azepin-2-one, 1-dodecylhexahydro-1-Dodecylazacycloheptan-2-oneTranzone1-Dodecylhexahydro-2H-azepin-2-oneN-Lauryl caprolactamLaurocapramum1-n-Dodecylazacycloheptan-2-One

16 more reported names

1F3X9DRV9XN-0252N-Dodecyl-epsilon-caprolactamRefChem:798570261-668-9N-DodecylcaprolactamC18H35NON-dodecyl-.epsilon.-caprolactamLaurocapramum [Latin]Caswell No. 064ALaurocapram [USAN:INN]USAF ND-72EINECS 261-668-9UNII-1F3X9DRV9XBRN 0167211TraZone

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:230266
ChEMBL:CHEMBL76591
EPA DTXSID:DTXSID0042086
PubMed:22766717
PubMed:22732268
PubMed:21959804
PubMed:21848502
PubMed:21056647
PubMed:20950659
PubMed:20845457
PubMed:20796187
PubMed:20582492
PubMed:20067437
PubMed:19900521
PubMed:19894269

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for LAUROCAPRAM

INCI name

LAUROCAPRAM

INN name

Laurocapram [USAN:INN]

Description

2H-Azepin-2-one, 1-dodecylhexahydro-

Record provenance

Inventory reference: 83773
Imported identity: LAUROCAPRAM
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for LAUROCAPRAM

Browse

Browse EU annexes

Explore Annex II–VI to see which substances are prohibited, restricted or permitted under specific conditions.

Search annex entries

Search the annex database for entries matching LAUROCAPRAM or related substances.

Key data

CAS

59227-89-3

261-668-9

Restriction

—

Function

SKIN CONDITIONING: Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#15002 · LAUROCAPRAM

Ingredients with overlapping formulation functions

LAURETH-2 ACETATESKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

LAURETH-2 ETHYLHEXANOATESKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SURFACTANT - CLEANSING

LAURIC/MYRISTIC/PALMITIC/STEARIC GLYCERIDESSKIN CONDITIONING

LAURIC/PALMITIC/OLEIC TRIGLYCERIDESKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

LAUROYL ARGININEHAIR CONDITIONING, SKIN CONDITIONING

LAUROYL GLUTAMIC ACIDSKIN CONDITIONING

LAUROYL HYDROLYZED COLLAGENANTISTATIC, HAIR CONDITIONING, SKIN CONDITIONING, SURFACTANT - CLEANSING

LAUROYL HYDROLYZED ELASTINHAIR CONDITIONING, SKIN CONDITIONING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How LAUROCAPRAM appears in the CosIng inventory

The CosIng inventory lists LAUROCAPRAM as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

LAUROCAPRAM is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

LAUROCAPRAM is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, LAUROCAPRAM carries the following function designation(s):

SKIN CONDITIONING

CAS 59227-89-3 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

View CAS records

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Open INCI Checker

Source note for LAUROCAPRAM

This page reproduces the CosIng inventory entry for LAUROCAPRAM from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research LAUROCAPRAM and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

View sources View updates

Tools & next steps

Check your formula

Scan a full INCI list to detect LAUROCAPRAM and any linked EU annex restrictions or allergen flags.

INCI Checker

Search similar ingredients

Find other inventory ingredients and annex entries related to LAUROCAPRAM, its identifiers or nearby name variants.