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CAS 42492-22-8 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 5695215/10/2010

LAUROYL ARGININE

N-Lauroyl-L-Arginine

LAUROYL ARGININE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 42492-22-8

CAS 42492-22-8PubChem CID 6451888

Lauroyl Arginine

The panel concluded that the 115 amino acid alkyl amides listed below are safe in the present practices of use and concentration in cosmetics, when formulated to be non-irritating...Lauroyl Arginine — Cosmetic Ingredient Review (CIR)

IUPAC name: (2S)-5-(diaminomethylideneamino)-2-(dodecanoylamino)pentanoic acid

Molecular formula: C18H36N4O3
Molecular weight: 356.5 g/mol
Exact mass: 356.27874102 Da
XLogP3: 3.5
Topological polar surface area: 131.0 Å²
Hydrogen-bond donors: 4
Hydrogen-bond acceptors: 4
Covalent units: 1
Defined stereocentres: 1

Also known as

N-Lauroyl-L-arginineN2-(1-Oxododecyl)-L-arginineEINECS 255-851-2UNII-65091WP61DAMISAFE AL 01AMISAFE AL-01L-ARGININE, N2-(1-OXODODECYL)-ARGININE, N2-LAUROYL-

16 more reported names

LAUROYL ARGININE [USP-RS]LAUROYL ARGININE (USP-RS)RefChem:152520LAUROYL ARGININE [INCI](S)-2-Dodecanamido-5-guanidinopentanoic acidN(ALPHA)-LAUROYL-L-ARGININE*Lauroyl L-ArginatelauroylarginineNalpha-DodecanoylarginineNalpha-Dodecanoyl-L-argininenalpha-lauroyl-l-argininemono-Na-lauroyl-L-arginineN~2~-dodecanoyl-L-argininemono-Nalpha-lauroyl-L-arginineNalpha-mono-lauroyl-L-arginineN-(1-OXODODECYL)ARGININE

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

EPA DTXSID:DTXSID10195279
PubMed:22938611

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for LAUROYL ARGININE

INCI name

LAUROYL ARGININE

Description

N-Lauroyl-L-Arginine

Record provenance

Inventory reference: 56952
Imported identity: LAUROYL ARGININE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for LAUROYL ARGININE

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Key data

CAS

42492-22-8

255-851-2

Restriction

—

Function

HAIR CONDITIONING: Enhancing the appearance and feel of hair. Leaving the hair easy to comb, supple, soft and shiny and/or imparting volume, lightness, gloss, texture, etc.
SKIN CONDITIONING: Maintaining the skin in good condition.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#15005 · LAUROYL ARGININE

Ingredients with overlapping formulation functions

LAURDIMONIUM HYDROXYPROPYL WHEAT AMINO ACIDSANTISTATIC, HAIR CONDITIONING

LAURETH-12 SUCCINATEHAIR CONDITIONING, SKIN CONDITIONING

LAURIMINODIPROPIONIC ACIDCLEANSING, HAIR CONDITIONING, SURFACTANT - CLEANSING

LAUROAMPHODIPROPIONIC ACIDCLEANSING, HAIR CONDITIONING, SURFACTANT - CLEANSING, SURFACTANT - FOAM BOOSTING, SURFACTANT - HYDR…

LAUROYL COLLAGEN AMINO ACIDSANTISTATIC, CLEANSING, HAIR CONDITIONING

LAUROYL HYDROLYZED COLLAGENANTISTATIC, HAIR CONDITIONING, SKIN CONDITIONING, SURFACTANT - CLEANSING

LAUROYL HYDROLYZED ELASTINHAIR CONDITIONING, SKIN CONDITIONING

LAUROYL LYSINEHAIR CONDITIONING, SKIN CONDITIONING, VISCOSITY CONTROLLING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How LAUROYL ARGININE appears in the CosIng inventory

The CosIng inventory lists LAUROYL ARGININE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

LAUROYL ARGININE is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

LAUROYL ARGININE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, LAUROYL ARGININE carries the following function designation(s):

CAS 42492-22-8 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for LAUROYL ARGININE

This page reproduces the CosIng inventory entry for LAUROYL ARGININE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research LAUROYL ARGININE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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