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CAS 66893-81-0 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 8323715/10/2010

PYRIDYLOXIDE T-BUTYLNITRONE

2-Propanamine, 2-Methyl-N-[(1-Oxido-4-Pyridinyl)Methylene]-, N-Oxide; 1,1-dimethyl-N-(4-pyridylmethylene)ethylamine N,N'-dioxide

PYRIDYLOXIDE T-BUTYLNITRONE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 66893-81-0

CAS 66893-81-0PubChem CID 135532295

alpha-(4-Pyridyl-1-oxide)-N-tert-butylnitrone

IUPAC name: N-tert-butyl-1-(1-oxidopyridin-1-ium-4-yl)methanimine oxide

Molecular formula: C10H14N2O2
Molecular weight: 194.23 g/mol
Exact mass: 194.105527694 Da
XLogP3: -0.2
Topological polar surface area: 54.2 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 2
Covalent units: 1
Defined stereocentres: 0

Also known as

POBN4-POBNPyridyloxide tert-butylnitrone2140SM8Q5ON-TERT-BUTYL-'A-(4-PYRIDL)NITRONE N'-OXIDE4-PyOBN4-pyridyl-1-oxide-T-butylnitroneRefChem:111041

16 more reported names

266-512-3N-tert-Butyl-alpha-(4-pyridyl-1-oxide)nitronealpha-(4-Pyridyl N-oxide)-N-tert-butylnitronetert-butyl-[(1-oxidanidylpyridin-4-ylidene)methyl]-oxidanylidene-azaniumtert-butyl-[(1-oxidopyridin-4-ylidene)methyl]-oxoazaniumPyridyloxide t-butylnitrone(Z)-2-methyl-N-((1-oxidopyridin-4-yl)methylene)propan-2-amine oxideAS-55806DA-66790HY-114713alpha-(4-pyridyl-N-oxide)-N-t-butylnitroneCS-0064148C-(4-PYRIDINYL-N-OXIDE)-N-TERT-BUTYLNITRONEN-tert-Butyl-|A-(4-pyridyl-1-oxide)nitrone(POBN).ALPHA.-(4-PYRIDYL-1-OXIDE)-N-T-BUTYLNITRONE.ALPHA.-(4-PYRIDYL-1-OXIDE)-N-TERT-BUTYLNITRONE

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

EPA DTXSID:DTXSID60217036
PubMed:17210446
PubMed:2022345

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for PYRIDYLOXIDE T-BUTYLNITRONE

INCI name

PYRIDYLOXIDE T-BUTYLNITRONE

Description

2-Propanamine, 2-Methyl-N-[(1-Oxido-4-Pyridinyl)Methylene]-, N-Oxide; 1,1-dimethyl-N-(4-pyridylmethylene)ethylamine N,N'-dioxide

Record provenance

Inventory reference: 83237
Imported identity: PYRIDYLOXIDE T-BUTYLNITRONE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for PYRIDYLOXIDE T-BUTYLNITRONE

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Key data

CAS

66893-81-0

266-512-3

Restriction

—

Function

ANTIOXIDANT: Inhibiting reactions promoted by oxygen, thus avoiding oxidation and rancidity.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#23751 · PYRIDYLOXIDE T-BUTYLNITRONE

Ingredients with overlapping formulation functions

PYRIDOXINE HYDROXYBENZOATEANTIOXIDANT, SKIN CONDITIONING

PYRIDOXINE HYDROXYCITRATEANTIOXIDANT, HAIR CONDITIONING, SKIN CONDITIONING

PYRIDOXINE SALICYLATEANTIOXIDANT, ASTRINGENT, SKIN CONDITIONING

PYRIDOXINE SERINATEANTIOXIDANT

PYRROLOQUINOLINE QUINONEANTIOXIDANT, HUMECTANT, SKIN CONDITIONING, SKIN PROTECTING

PYRROLOQUINOLINE QUINONE ALLYL ESTERANTIOXIDANT

PYRUS MALUS PEEL EXTRACTANTIOXIDANT

PYRUS MALUS POMACE EXTRACTANTIOXIDANT, SKIN CONDITIONING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How PYRIDYLOXIDE T-BUTYLNITRONE appears in the CosIng inventory

The CosIng inventory lists PYRIDYLOXIDE T-BUTYLNITRONE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

PYRIDYLOXIDE T-BUTYLNITRONE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

PYRIDYLOXIDE T-BUTYLNITRONE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, PYRIDYLOXIDE T-BUTYLNITRONE carries the following function designation(s):

ANTIOXIDANT

CAS 66893-81-0 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for PYRIDYLOXIDE T-BUTYLNITRONE

This page reproduces the CosIng inventory entry for PYRIDYLOXIDE T-BUTYLNITRONE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research PYRIDYLOXIDE T-BUTYLNITRONE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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