What other records share CAS 72909-34-3?

CAS 72909-34-3 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains PYRROLOQUINOLINE QUINONE?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 9549530/04/2018

PYRROLOQUINOLINE QUINONE

1H-Pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid, 4,5-dihydro-4,5-dioxo-,PQQ

PYRROLOQUINOLINE QUINONE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

INCI Checker Compare all markets Search similar

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Markets and their official sources Search every market for this name

Chemical identity and properties

PubChem 2D chemical structure for CAS 72909-34-3

CAS 72909-34-3PubChem CID 1024

Pyrroloquinoline Quinone

Pyrroloquinoline quinone is a pyrroloquinoline having oxo groups at the 4- and 5-positions and carboxy groups at the 2-, 7- and 9-positions. It has a role as an antioxidant, a cofactor, a water-soluble vitamin (role) and an anti-inflammatory agent. It is a member of orthoquinones, a pyrroloquinoline cofactor and a tricarboxylic acid. It is a conjugate acid of a pyrroloquinoline quinone(3-). — ChEBI

IUPAC name: 4,5-dioxo-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid

Molecular formula: C14H6N2O8
Molecular weight: 330.21 g/mol
Exact mass: 330.01241515 Da
XLogP3: -0.1
Topological polar surface area: 175.0 Å²
Hydrogen-bond donors: 4
Hydrogen-bond acceptors: 9
Covalent units: 1
Defined stereocentres: 0

Also known as

methoxatinCoenzyme pqqPyrrolo-quinoline quinonePqq coenzymePqq cofactor4,5-dioxo-1H,4H,5H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid2,7,9-Tricarboxypyrroloquinoline quinoneCHEBI:18315

16 more reported names

2,7,9-Tricarboxy-1H-pyrrolo(2,3-f)quinoline-4,5-dionepyrroloquinolinedione tricarboxylic acid1H-Pyrrolo(2,3-f)quinoline-2,7,9-tricarboxylic acid, 4,5-dihydro-4,5-dioxo-2,4,6-tricarboxylic-pyrrolo[2,3-5,6]quinoline 8,9-quinoneCoenzyme, PQQCofactor, PQQPQQ, CoenzymeQuinone, PyrroloquinolinePyrrolo Quinoline QuinoneQuinone, Pyrrolo-Quinoline2,4,6-tricarboxylic-pyrrolo(2,3-5,6)quinoline 8,9-quinone4,5-dioxo-1H-pyrrolo(2,3-f)quinoline-2,7,9-tricarboxylic acid4,5-dioxo-1H,4H,5H-pyrrolo(2,3-f)quinoline-2,7,9-tricarboxylic acid1H-Pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid, 4,5-dihydro-4,5-dioxo-4,5-dihydro-4,5-dioxo-1H-pyrrolo(2,3-5,6)quinoline-2,7,9-tricarboxylic acid4,5-dihydro-4,5-dioxo-1H-pyrrolo[2,3-5,6]quinoline-2,7,9-tricarboxylic acid

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

ChEBI:CHEBI:18315
ChEMBL:CHEMBL1235421
EPA DTXSID:DTXSID3041162
PubMed:32860006
PubMed:32068067
PubMed:31226464
PubMed:30240821
PubMed:28578007
PubMed:28115068
PubMed:27108097
PubMed:26343954
PubMed:26276080
PubMed:25843018
PubMed:24755484
PubMed:23009682

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for PYRROLOQUINOLINE QUINONE

INCI name

PYRROLOQUINOLINE QUINONE

Description

1H-Pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid, 4,5-dihydro-4,5-dioxo-,PQQ

Record provenance

Inventory reference: 95495
Imported identity: PYRROLOQUINOLINE QUINONE
Source update: 30/04/2018

European Commission CosIng source notes

Annex records for PYRROLOQUINOLINE QUINONE

Browse

Browse EU annexes

Explore Annex II–VI to see which substances are prohibited, restricted or permitted under specific conditions.

Search annex entries

Search the annex database for entries matching PYRROLOQUINOLINE QUINONE or related substances.

Key data

CAS

72909-34-3

—

Restriction

—

Function

ANTIOXIDANT: Inhibiting reactions promoted by oxygen, thus avoiding oxidation and rancidity.
HUMECTANT: Retaining and/or preserving the moisture in a product during use.
SKIN CONDITIONING: Maintaining the skin in good condition.
SKIN PROTECTING: Helping to avoid harmful effects to the skin from external factors.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#23766 · PYRROLOQUINOLINE QUINONE

Ingredients with overlapping formulation functions

PURPUROGALLINHUMECTANT, SKIN CONDITIONING

PYRENARIA BUISANENSIS LEAF EXTRACTHUMECTANT, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

PYRIDOXINE DILAURATEANTISTATIC, HAIR CONDITIONING, HUMECTANT, SKIN CONDITIONING

PYRIDOXINE TRIS-HEXYLDECANOATEHUMECTANT

PYRUS SEROTINA CALLUS EXTRACTANTI-SEBUM, ANTIOXIDANT, HAIR CONDITIONING, HUMECTANT, SKIN CONDITIONING, SKIN CONDITIONING - EMOLL…

QUERCUS ACUTISSIMA EXTRACTANTIMICROBIAL, DEODORANT, HUMECTANT, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

QUERCUS ACUTISSIMA WOOD VINEGAR EXTRACTHUMECTANT, SKIN CONDITIONING

QUERCUS GLAUCA WOOD VINEGARHUMECTANT, SKIN CONDITIONING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How PYRROLOQUINOLINE QUINONE appears in the CosIng inventory

The CosIng inventory lists PYRROLOQUINOLINE QUINONE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

PYRROLOQUINOLINE QUINONE is also tagged with 4 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

PYRROLOQUINOLINE QUINONE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, PYRROLOQUINOLINE QUINONE carries the following function designation(s):

CAS 72909-34-3 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

View CAS records

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Open INCI Checker

Source note for PYRROLOQUINOLINE QUINONE

This page reproduces the CosIng inventory entry for PYRROLOQUINOLINE QUINONE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research PYRROLOQUINOLINE QUINONE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

View sources View updates

Tools & next steps

Check your formula

Scan a full INCI list to detect PYRROLOQUINOLINE QUINONE and any linked EU annex restrictions or allergen flags.

INCI Checker

Search similar ingredients

Find other inventory ingredients and annex entries related to PYRROLOQUINOLINE QUINONE, its identifiers or nearby name variants.