What does the restriction note for CALCIUM THIOGLYCOLATE HYDROXIDE mean?

The restriction field for CALCIUM THIOGLYCOLATE HYDROXIDE reads: III/2a. This is the restriction note from the CosIng inventory. For authoritative conditions and limits, always refer to the linked annex entries.

How do I check if my formula contains CALCIUM THIOGLYCOLATE HYDROXIDE?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 8234515/10/2010

CALCIUM THIOGLYCOLATE HYDROXIDE

Acetic Acid, Mercapto-, Calcium Salt (1:1), Trihydrate; Calcium sulphidoacetate

CALCIUM THIOGLYCOLATE HYDROXIDE is linked to 1 EU annex record on this page. Inventory note: III/2a.

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Regulatory evidence by market

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Market	Evidence status	Records	Source language
European Union	Evidence linked Restricted entry found Open this evidence	1	English and EU languages
Great Britain	Source mapped Official source mapped; ingredient rule not imported	0	English
Canada	Source mapped Official source mapped; ingredient rule not imported	0	English and French
New Zealand	Source mapped Official source mapped; ingredient rule not imported	0	English
ASEAN	Source mapped Official source mapped; ingredient rule not imported	0	English and national languages
China	Source mapped Official source mapped; ingredient rule not imported	0	Chinese with selected English material
Japan	Source mapped Official source mapped; ingredient rule not imported	0	Japanese; official English translation available
South Korea	Source mapped Official source mapped; ingredient rule not imported	0	Korean with some English names
United States	Source mapped Official source mapped; ingredient rule not imported	0	English
Australia	Source mapped Official source mapped; ingredient rule not imported	0	English
Brazil	Source mapped Official source mapped; ingredient rule not imported	0	Portuguese with INCI crosswalks
India	Source mapped Official source mapped; ingredient rule not imported	0	English and Hindi
Saudi Arabia	Source mapped Official source mapped; ingredient rule not imported	0	Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 29820-13-1

CAS 29820-13-1PubChem CID 22039

(2-(Mercapto-kappaS)acetato(2-)-kappaO)calcium

IUPAC name: calcium 2-sulfidoacetate

Molecular formula: C2H2CaO2S
Molecular weight: 130.18 g/mol
Exact mass: 129.9401413 Da
Topological polar surface area: 41.1 Å²
Hydrogen-bond donors: 0
Hydrogen-bond acceptors: 3
Covalent units: 2
Defined stereocentres: 0

Also known as

Calcium, (mercaptoacetato(2-)-O,S)-Calcium, [mercaptoacetato(2-)-O,S]-(Mercaptoacetato(2-)-O,S)calciumMercaptoacetic acid, monocalcium saltCalcium, (2-(mercapto-kappaS)acetato(2-)-kappaO)-RefChem:395121253-511-8Calcium thioglycolate (1:1)

12 more reported names

Calcium sulphidoacetatecalcium;2-sulfidoacetateAcetic acid, mercapto-, calcium salt (1:1)Thioglycolic acid calcium saltAcetic acid, 2-mercapto-, calcium salt (1:1)EINECS 249-881-5calcium sulfidoacetateC2H2CaO2SEC 249-881-5Mercaptoacetic Acid Calcium SaltQVCFQEFEMBCIOI-UHFFFAOYSA-LDB-369920

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

EPA DTXSID:DTXSID00890822

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

PubChem 2D chemical structure for CAS 65208-41-5

CAS 65208-41-5PubChem CID 56840831

Calcium sulfidoacetate--water (1/1/3)

IUPAC name: calcium;2-sulfidoacetate;trihydrate

Molecular formula: C2H8CaO5S
Molecular weight: 184.23 g/mol
Exact mass: 183.9718354 Da
Topological polar surface area: 44.1 Å²
Hydrogen-bond donors: 3
Hydrogen-bond acceptors: 6
Covalent units: 5
Defined stereocentres: 0

Also known as

RefChem:331596C2H8CaO5SUM6R6Q3WPX

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

EPA DTXSID:DTXSID90746900

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for CALCIUM THIOGLYCOLATE HYDROXIDE

INCI name

CALCIUM THIOGLYCOLATE HYDROXIDE

Description

Acetic Acid, Mercapto-, Calcium Salt (1:1), Trihydrate; Calcium sulphidoacetate

Record provenance

Inventory reference: 82345
Imported identity: CALCIUM THIOGLYCOLATE HYDROXIDE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for CALCIUM THIOGLYCOLATE HYDROXIDE

Annex III Restriction reference

Entry 2a

THIOGLYCOLIC ACID

CAS: 68-11-1

EC: 200-677-4

Key data

CAS

65208-41-5 / 29820-13-1

- / 249-881-5

Restriction

III/2a

Function

DEPILATORY: Breaking down the mechanical strength of hair fibers so that they can be removed by mild scraping/rubbing.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#4991 · CALCIUM THIOGLYCOLATE HYDROXIDE

Ingredients with overlapping formulation functions

C4-6 OLEFIN/STYRENE COPOLYMERDEPILATORY, SKIN CONDITIONING

C5-6 OLEFIN/STYRENE COPOLYMERDEPILATORY, SKIN CONDITIONING

CALCIUM SULFIDEDEPILATORY

CALCIUM THIOGLYCOLATEDEPILATORY, KERATOLYTIC, REDUCING

COLOPHONIUMBINDING, DEPILATORY, FILM FORMING, VISCOSITY CONTROLLING

COPERNICIA CERIFERA WAXDEPILATORY

DICYCLOPENTADIENE/ISOPENTENE/ISOPRENE COPOLYMERBINDING, DEPILATORY, PLASTICISER

DICYCLOPENTADIENE/ISOPENTENE/ISOPRENE/STYRENE COPOLYMERBINDING, DEPILATORY, PLASTICISER

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How CALCIUM THIOGLYCOLATE HYDROXIDE appears in the CosIng inventory

The CosIng inventory lists CALCIUM THIOGLYCOLATE HYDROXIDE as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

CALCIUM THIOGLYCOLATE HYDROXIDE is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

CALCIUM THIOGLYCOLATE HYDROXIDE appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for CALCIUM THIOGLYCOLATE HYDROXIDE reads: "III/2a". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, CALCIUM THIOGLYCOLATE HYDROXIDE carries the following function designation(s):

DEPILATORY

CAS 65208-41-5 / 29820-13-1 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for CALCIUM THIOGLYCOLATE HYDROXIDE

This page combines the CosIng inventory entry for CALCIUM THIOGLYCOLATE HYDROXIDE with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research CALCIUM THIOGLYCOLATE HYDROXIDE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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