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CAS 14618-65-6 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

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InventoryRef 8076715/10/2010

THIODIGLYCOLAMIDE

2,2'-thiobisacetamide

THIODIGLYCOLAMIDE is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 14618-65-6

CAS 14618-65-6PubChem CID 26768

Acetamide, 2,2'-thiobis-

IUPAC name: 2-(2-amino-2-oxoethyl)sulfanylacetamide

Molecular formula: C4H8N2O2S
Molecular weight: 148.19 g/mol
Exact mass: 148.03064868 Da
XLogP3: -1.2
Topological polar surface area: 111.0 Å²
Hydrogen-bond donors: 2
Hydrogen-bond acceptors: 3
Covalent units: 1
Defined stereocentres: 0

Also known as

2,2'-ThiobisacetamideThiodiglycolamideThiodiacetamideThiobisacetamide2,2'-Thio-bis-acetamideEINECS 238-657-2G4Y5Q1UXX2NSC 82327

16 more reported names

BRN 1764428MEXORYL SANSC-823274-03-00-00625 (Beilstein Handbook Reference)RefChem:551534THIODIGLYCOLAMIDE [INCI]2,2'-Thiodiacetamide2,2/'-THIODIACETAMIDE2-(carbamoylmethylthio)acetamideUNII-G4Y5Q1UXX2monothiodiacetamideAcetamide,2'-thiobis-2,2'-Thiobis(acetamide)WLN: ZV1S1VZ2,2'-Sulfanediyldiacetamide2-Carbamoylmethylsulfanyl-acetamide

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External database identifiers

ChEMBL:CHEMBL171496
EPA DTXSID:DTXSID30163293

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for THIODIGLYCOLAMIDE

INCI name

THIODIGLYCOLAMIDE

Description

2,2'-thiobisacetamide

Record provenance

Inventory reference: 80767
Imported identity: THIODIGLYCOLAMIDE
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for THIODIGLYCOLAMIDE

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Key data

CAS

14618-65-6

238-657-2

Restriction

—

Function

ANTIOXIDANT: Inhibiting reactions promoted by oxygen, thus avoiding oxidation and rancidity.
HAIR CONDITIONING: Enhancing the appearance and feel of hair. Leaving the hair easy to comb, supple, soft and shiny and/or imparting volume, lightness, gloss, texture, etc.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#28760 · THIODIGLYCOLAMIDE

Ingredients with overlapping formulation functions

THIOCTOYL TETRAPEPTIDE-3ANTIOXIDANT

THIOCTOYL TRIPEPTIDE-1ANTIOXIDANT, HAIR CONDITIONING, SKIN PROTECTING

THIOCTOYL TRIPEPTIDE-35ANTIOXIDANT, BLEACHING, HAIR CONDITIONING, SKIN PROTECTING

THIODIGLYCOLANTIOXIDANT

THIODIGLYCOLIC ACIDANTIOXIDANT, REDUCING

THIOGLYCOLIC ACIDANTIOXIDANT, DEPILATORY, HAIR WAVING OR STRAIGHTENING, REDUCING

THIOHISTIDINEANTIOXIDANT, BLEACHING, CHELATING

THIOLACTIC ACIDANTIOXIDANT, DEPILATORY, FRAGRANCE, HAIR WAVING OR STRAIGHTENING, REDUCING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How THIODIGLYCOLAMIDE appears in the CosIng inventory

The CosIng inventory lists THIODIGLYCOLAMIDE as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

THIODIGLYCOLAMIDE is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

THIODIGLYCOLAMIDE is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, THIODIGLYCOLAMIDE carries the following function designation(s):

CAS 14618-65-6 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for THIODIGLYCOLAMIDE

This page reproduces the CosIng inventory entry for THIODIGLYCOLAMIDE from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research THIODIGLYCOLAMIDE and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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