QUATERNIUM-22
3-(D-Gluconoylamino)propyl(2-hydroxyethyl)dimethylammonium chloride
QUATERNIUM-22 is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.
Regulatory evidence by market
No rule for this ingredient has been imported for any of the 13 markets tracked here.
That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.
Chemical identity and properties
Quaternium 22
Quaternium-22 is a quaternary ammonium salt found in numerous cosmetics. Its toxicity is due to its ability to act as a nitrosating agent, releasing potentially carcinogenic nitrosamines. (L1890) — Toxin and Toxin Target Database (T3DB)
- IUPAC name
- 2-hydroxyethyl-dimethyl-[3-[[(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoyl]amino]propyl]azanium chloride
- Molecular formula
- C13H29ClN2O7
- Molecular weight
- 360.83 g/mol
- Exact mass
- 360.1663290 Da
- Topological polar surface area
- 150.0 Ų
- Hydrogen-bond donors
- 7
- Hydrogen-bond acceptors
- 8
- Covalent units
- 2
- Defined stereocentres
- 4
Also known as
14 more reported names
External database identifiers
- EPA DTXSID:DTXSID601014646
Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.
Inventory details for QUATERNIUM-22
INCI name
QUATERNIUM-22
Description
3-(D-Gluconoylamino)propyl(2-hydroxyethyl)dimethylammonium chloride
Record provenance
- Inventory reference
- 79242
- Imported identity
- QUATERNIUM-22
- Source update
- 15/10/2010
Annex records for QUATERNIUM-22
Key data
- ANTISTATIC
- Preventing and/or reducing static electricity by neutralising electrical charge on surfaces.
- FILM FORMING
- Producing (upon application) a continuous film on the skin, hair or nails.
- HAIR CONDITIONING
- Enhancing the appearance and feel of hair. Leaving the hair easy to comb, supple, soft and shiny and/or imparting volume, lightness, gloss, texture, etc.
Official EU ingredient-name evidence
The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.
Related inventory evidence
Ingredients with overlapping formulation functions
Additional official and scientific sources
11 external databases to check this identity in
Each link searches that source for this identity. What each source is, and its legal weight
How QUATERNIUM-22 appears in the CosIng inventory
The CosIng inventory lists QUATERNIUM-22 as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.
QUATERNIUM-22 is also tagged with 3 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.
Frequently asked questions
Source note for QUATERNIUM-22
This page reproduces the CosIng inventory entry for QUATERNIUM-22 from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.
Use this inventory page to research QUATERNIUM-22 and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.
Tools & next steps
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