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InventoryRef 3740715/10/2010

QUATERNIUM-16

Quaternary ammonium compounds, tris(hydroxyethyl)tallow alkyl, chlorides

QUATERNIUM-16 is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

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Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

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Chemical identity and properties

PubChem 2D chemical structure for CAS 35239-12-4
CAS 35239-12-4PubChem CID 18401232

Quaternium-16

IUPAC name
tris(2-hydroxyethyl)-octadecylazanium chloride
Molecular formula
C24H52ClNO3
Molecular weight
438.1 g/mol
Exact mass
437.3635722 Da
Topological polar surface area
60.7 Ų
Hydrogen-bond donors
3
Hydrogen-bond acceptors
4
Covalent units
2
Defined stereocentres
0

Also known as

Quaternium-16 [INCI]K4H0FG9I2TTris(2-hydroxyethyl)(stearyl)ammonium chlorideOctadecanaminium, N,N,N-tris(2-hydroxyethyl)-, chlorideRefChem:871335UNII-K4H0FG9I2Ttris(2-hydroxyethyl)-octadecylazanium;chlorideN,N,N-Tris(2-hydroxyethyl)octadecan-1-aminium chloride
Open full PubChem recordPubChem annotations3D structure image
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for QUATERNIUM-16

INCI name

QUATERNIUM-16

Description

Quaternary ammonium compounds, tris(hydroxyethyl)tallow alkyl, chlorides

Record provenance

Inventory reference
37407
Imported identity
QUATERNIUM-16
Source update
15/10/2010
European Commission CosIng source notes
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Key data

CAS
64425-88-3 / 35239-12-4
EC
264-890-4 / -
Restriction
—
Function
ANTISTATIC
Preventing and/or reducing static electricity by neutralising electrical charge on surfaces.
HAIR CONDITIONING
Enhancing the appearance and feel of hair. Leaving the hair easy to comb, supple, soft and shiny and/or imparting volume, lightness, gloss, texture, etc.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#23837 · QUATERNIUM-16

Ingredients with overlapping formulation functions

PYRIDOXINE DIPALMITATEANTISTATIC, HAIR CONDITIONING, SKIN CONDITIONING
PYRIDOXINE HCLANTISTATIC, HAIR CONDITIONING, SKIN CONDITIONING
PYRIDOXINE TRIPALMITATEANTISTATIC, HAIR CONDITIONING, SKIN CONDITIONING
QUATERNIUM-14ANTIMICROBIAL, ANTISTATIC, HAIR CONDITIONING, SURFACTANT - CLEANSING
QUATERNIUM-18ANTISTATIC, HAIR CONDITIONING, SURFACTANT - CLEANSING
QUATERNIUM-18 METHOSULFATEANTISTATIC
QUATERNIUM-22ANTISTATIC, FILM FORMING, HAIR CONDITIONING
QUATERNIUM-24ANTIMICROBIAL, ANTISTATIC, SURFACTANT - CLEANSING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicalsPubChem PUG RESTEU Safety Gate cosmetic product alertsECHA CHEMUS EPA CompToxCosmetic Ingredient Review safety assessmentsFDA Global Substance Registration SystemILO/WHO International Chemical Safety CardsJapan NITE-CHRIPNIOSH Pocket Guide to Chemical HazardsOECD eChemPortal

How QUATERNIUM-16 appears in the CosIng inventory

The CosIng inventory lists QUATERNIUM-16 as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

QUATERNIUM-16 is also tagged with 2 cosmetic functions in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

QUATERNIUM-16 is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, QUATERNIUM-16 carries the following function designation(s):

CAS 64425-88-3 / 35239-12-4 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Source note for QUATERNIUM-16

This page reproduces the CosIng inventory entry for QUATERNIUM-16 from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research QUATERNIUM-16 and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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