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InventoryRef 6024715/10/2010

TETRAMETHYLOLGLYCOLURIL

Imidazo[4,5-d]imidazole-2,5(1H,3H)-dione, tetrahydro-1,3,4,6-tetrakis(hydroxymethyl)-

TETRAMETHYLOLGLYCOLURIL is listed in the EU CosIng inventory, but no direct annex records are linked on this page yet.

Regulatory evidence by market

No rule for this ingredient has been imported for any of the 13 markets tracked here.

That describes this inventory, not the law. No imported rule is not evidence that an ingredient is permitted: a rule may exist under another name or identifier, or in a dataset not yet imported here.

Chemical identity and properties

PubChem 2D chemical structure for CAS 5395-50-6
CAS 5395-50-6PubChem CID 79372

Tetramethylolglycoluril

IUPAC name
1,3,4,6-tetrakis(hydroxymethyl)-3a,6a-dihydroimidazo[4,5-d]imidazole-2,5-dione
Molecular formula
C8H14N4O6
Molecular weight
262.22 g/mol
Exact mass
262.09133418 Da
XLogP3
-2.1
Topological polar surface area
128.0 Ų
Hydrogen-bond donors
4
Hydrogen-bond acceptors
6
Covalent units
1
Defined stereocentres
0

Also known as

Tetramethylol acetylenediureaFixapret 140Tetrakis(hydroxymethyl)glycolurilTetramethylol acetylene diurieneGROTAN TK6NSC 3319NSC-67452Glycoluril, 1,3,4,6-tetrakis(hydroxymethyl)-
16 more reported names
3BH30G5P9HACTICIDE F(N)NSC-3319EINECS 226-408-0NSC 67452N,N',N'',N'''-Tetrakis(hydroxymethyl)glycolurilAI3-22154TETRAMETHYLOLACETYLENEDIUREAImidazo(4,5-d)imidazole-2,5(1H,3H)-dione, tetrahydro-1,3,4,6-tetrakis(hydroxymethyl)-Imidazo[4,5-d]imidazole-2,5(1H,3H)-dione, tetrahydro-1,3,4,6-tetrakis(hydroxymethyl)-TETRAKIS(HYDROXYMETHYL)ACETYLENEUREA2,4,6,8-TETRAKIS(HYDROXYMETHYL)GLYCOLURIL2,5-DIOXO-1,3,4,6-TETRAKIS(HYDROXYMETHYL)HEXAHYDROIMIDAZO(4,5-D)IMIDAZOLETetrahydro-1,3,4,6-tetrakis(hydroxymethyl)imidazo(4,5-d)imidazole-2,5(1H,3H)-dionetetrahydro-1,3,4,6-tetrakis(hydroxymethyl)imidazo[4,5-d]imidazole-2,5(1h,3h)-dioneTETRAHYDRO-1,3,4,6-TETRAKIS(HYDROXYMETHYL)IMIDAZOL(4,5-D)IMIDAZOLE-2,5-(1H,3H)DIONE
External database identifiers

Retrieved from NIH PubChem on 2026-08-31 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for TETRAMETHYLOLGLYCOLURIL

INCI name

TETRAMETHYLOLGLYCOLURIL

Description

Imidazo[4,5-d]imidazole-2,5(1H,3H)-dione, tetrahydro-1,3,4,6-tetrakis(hydroxymethyl)-

Record provenance

Inventory reference
60247
Imported identity
TETRAMETHYLOLGLYCOLURIL
Source update
15/10/2010
European Commission CosIng source notes

Key data

Restriction
Function
ANTIMICROBIAL
Preventing and/or slowing down microbial growth.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

Ingredients with overlapping formulation functions

Additional official and scientific sources

11 external databases to check this identity in

How TETRAMETHYLOLGLYCOLURIL appears in the CosIng inventory

The CosIng inventory lists TETRAMETHYLOLGLYCOLURIL as a cosmetic ingredient and this page links it to 0 annex records. The inventory entry captures names and identifiers, while the annex records show where the substance is prohibited, restricted or positively listed in EU cosmetics law.

TETRAMETHYLOLGLYCOLURIL is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

TETRAMETHYLOLGLYCOLURIL is listed in the EU CosIng ingredient inventory with no direct annex restriction records linked at this time. Absence of an annex link does not guarantee unrestricted use — always verify against the current official CosIng database before formulating.

According to the EU CosIng inventory, TETRAMETHYLOLGLYCOLURIL carries the following function designation(s):

CAS 5395-50-6 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

Source note for TETRAMETHYLOLGLYCOLURIL

This page reproduces the CosIng inventory entry for TETRAMETHYLOLGLYCOLURIL from public European Commission cosmetic ingredient materials and shows linked identifiers even when no direct annex match is currently attached.

Use this inventory page to research TETRAMETHYLOLGLYCOLURIL and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

Tools & next steps

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