What does the restriction note for SOLVENT YELLOW 44 mean?

The restriction field for SOLVENT YELLOW 44 reads: II/1277. This is the restriction note from the CosIng inventory. For authoritative conditions and limits, always refer to the linked annex entries.

What other records share CAS 2478-20-8?

CAS 2478-20-8 may appear across multiple EU annex records. The CAS lookup page shows all Annex II–VI entries sharing this identifier, useful for identifying cross-annex regulatory status of the same chemical substance.

How do I check if my formula contains SOLVENT YELLOW 44?

Use the INCI Checker to screen a full ingredient list across selected markets, or use the substance market comparison to review this identity across all supported market datasets.

InventoryRef 3816215/10/2010

SOLVENT YELLOW 44

6-amino-2-(2,4-dimethylphenyl)-1H-benz[de]isoquinoline-1,3(2H)-dione (CI 56200)

SOLVENT YELLOW 44 is linked to 1 EU annex record on this page. Inventory note: II/1277.

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Regulatory evidence by market

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Market	Evidence status	Records	Source language
European Union	Evidence linked Prohibited entry found Open this evidence	1	English and EU languages
Great Britain	Evidence linked Prohibited Open this evidence	1	English
Canada	Source mapped Official source mapped; ingredient rule not imported	0	English and French
New Zealand	Evidence linked Prohibited Open this evidence	1	English
ASEAN	Evidence linked Prohibited Open this evidence	1	English and national languages
China	Evidence linked Prohibited Open this evidence	1	Chinese with selected English material
Japan	Source mapped Official source mapped; ingredient rule not imported	0	Japanese; official English translation available
South Korea	Evidence linked Prohibited Open this evidence	1	Korean with some English names
United States	Source mapped Official source mapped; ingredient rule not imported	0	English
Australia	Source mapped Official source mapped; ingredient rule not imported	0	English
Brazil	Evidence linked Prohibited Open this evidence	1	Portuguese with INCI crosswalks
India	Evidence linked Prohibited Open this evidence	1	English and Hindi
Saudi Arabia	Evidence linked Prohibited Open this evidence	1	Arabic and English

Chemical identity and properties

PubChem 2D chemical structure for CAS 2478-20-8

CAS 2478-20-8PubChem CID 75589

Solvent Yellow 44

IUPAC name: 6-amino-2-(2,4-dimethylphenyl)benzo[de]isoquinoline-1,3-dione

Molecular formula: C20H16N2O2
Molecular weight: 316.4 g/mol
Exact mass: 316.121177757 Da
XLogP3: 3.8
Topological polar surface area: 63.4 Å²
Hydrogen-bond donors: 1
Hydrogen-bond acceptors: 3
Covalent units: 1
Defined stereocentres: 0

Also known as

Disperse Yellow 111H-Benz[de]isoquinoline-1,3(2H)-dione, 6-amino-2-(2,4-dimethylphenyl)-BM6Y3B8SJYC.I. SOLVENT YELLOW 135Naphthalimide, 4-amino-N-2,4-xylyl-C.I. SOLVENT YELLOW 44C.I. DISPERSE YELLOW 111H-Benz(de)isoquinoline-1,3(2H)-dione, 6-amino-2-(2,4-dimethylphenyl)-

16 more reported names

6-Amino-2-(2,4-dimethylphenyl)-1H-benz(de)isoquinoline-1,3(2H)-dione6-amino-2-(2,4-dimethylphenyl)-1H-benz[de]isoquinoline-1,3(2H)-dioneC.I. 562004-AMINO-1,8-NAPHTHAL-2',4'-DIMETHYLPHENYLIMIDERefChem:888161SOLVENT YELLOW 44 [INCI]1H-Benzdeisoquinoline-1,3(2H)-dione, 6-amino-2-(2,4-dimethylphenyl)-604-404-36-Amino-2-(2,4-dimethylphenyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione4-amino-N-2,4-xylyl-1,8-naphthalimideFD&C Yellow 114-Amino-N-(2,4-dimethylphenyl)naphthalene-1,8-dicarboximideCI 56200Solvent Yellow 135solventyellow44solvent yellow 85

Open full PubChem record PubChem annotations 3D structure image

External database identifiers

EPA DTXSID:DTXSID7062453

Retrieved from NIH PubChem on 2026-09-02 by checksum-valid CAS matching. Chemical properties do not replace the regulatory decision on this page.

Inventory details for SOLVENT YELLOW 44

INCI name

SOLVENT YELLOW 44

Description

6-amino-2-(2,4-dimethylphenyl)-1H-benz[de]isoquinoline-1,3(2H)-dione (CI 56200)

Record provenance

Inventory reference: 38162
Imported identity: SOLVENT YELLOW 44
Source update: 15/10/2010

European Commission CosIng source notes

Annex records for SOLVENT YELLOW 44

Annex II Restriction reference

Entry 1277

6-Amino-2-((2,4-dimethylphenyl)-1H-benz[de]isoquinoline-1,3(2H)-dione (Solvent Yellow 44) and its s…

CAS: 2478-20-8

EC: 219-607-9

Key data

CAS

2478-20-8

219-607-9

Restriction

II/1277

Function

HAIR DYEING: Imparting color to hair. Hair dyeing preparations may be temporary, semi-permanent, or permanent, depending on the length of time the colorant remains on the hair.

Official EU ingredient-name evidence

The ingredient name exactly matches the official 2025 EU glossary of common ingredient names.

#27223 · SOLVENT YELLOW 44

Ingredients with overlapping formulation functions

SOLVENT YELLOW 172HAIR DYEING

SOLVENT YELLOW 18HAIR DYEING

SOLVENT YELLOW 29HAIR DYEING

SOLVENT YELLOW 33HAIR DYEING

SOLVENT YELLOW 85HAIR DYEING

TAMARIX GALLICA GALL POWDERHAIR CONDITIONING; HAIR DYEING

TETRAAMINOPYRIMIDINE SULFATEHAIR DYEING

TETRABROMOPHENOL BLUEHAIR DYEING

Additional official and scientific sources

11 external databases to check this identity in

Each link searches that source for this identity. What each source is, and its legal weight

ECHA CHEM / Information on chemicals PubChem PUG REST EU Safety Gate cosmetic product alerts ECHA CHEM US EPA CompTox Cosmetic Ingredient Review safety assessments FDA Global Substance Registration System ILO/WHO International Chemical Safety Cards Japan NITE-CHRIP NIOSH Pocket Guide to Chemical Hazards OECD eChemPortal

How SOLVENT YELLOW 44 appears in the CosIng inventory

The CosIng inventory lists SOLVENT YELLOW 44 as a cosmetic ingredient and this page links it to 1 annex record. The inventory entry captures names and identifiers, while the annex record shows where the substance is prohibited, restricted or positively listed in EU cosmetics law.

SOLVENT YELLOW 44 is also tagged with 1 cosmetic function in the official data. Function labels describe intended use, but they do not replace regulatory review of linked annex records before formulation or labelling work.

Frequently asked questions

SOLVENT YELLOW 44 appears in the EU CosIng inventory and has linked annex records. Check the annex records above for applicable restrictions, concentration limits and conditions of use. Annex II listing means prohibited; Annex III means restricted; Annexes IV, V and VI mean permitted under specified conditions.

The restriction field for SOLVENT YELLOW 44 reads: "II/1277". This is the restriction note recorded in the CosIng inventory for this ingredient. For authoritative conditions and limits, always refer to the linked annex entries above.

According to the EU CosIng inventory, SOLVENT YELLOW 44 carries the following function designation(s):

HAIR DYEING

CAS 2478-20-8 may appear across multiple EU annex records. Viewing the CAS lookup page shows all Annex II–VI entries sharing this identifier, which is useful for identifying cross-annex regulatory status of the same chemical substance.

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Use the INCI Checker to screen a full ingredient list across selected markets, or compare this substance across all supported market datasets.

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Source note for SOLVENT YELLOW 44

This page combines the CosIng inventory entry for SOLVENT YELLOW 44 with 1 linked Annex II–VI record from the local dataset built from public European Commission cosmetic ingredient materials.

Use this inventory page to research SOLVENT YELLOW 44 and compare linked records, but verify restrictions and legal status against the current official source text and law before making regulatory decisions.

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Tools & next steps

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